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https://www.readbyqxmd.com/read/29342436/iris-melanoma-outcomes-based-on-the-american-joint-committee-on-cancer-classification-eighth-edition-in-432-patients
#1
Carol L Shields, Maura Di Nicola, Vladislav P Bekerman, Swathi Kaliki, Carolina Alarcon, Enzo Fulco, Jerry A Shields
PURPOSE: The American Joint Committee on Cancer (AJCC) classification was updated to the eighth edition in January 2017, providing staging for iris melanoma. This study evaluated outcomes of iris melanoma per the AJCC classification, eighth edition. DESIGN: Retrospective case series. PARTICIPANTS: Four hundred thirty-two patients with iris melanoma. METHODS: Management including tumor resection, plaque radiotherapy, or enucleation...
January 13, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29342409/development-and-characterization-of-an-allergoid-of-cat-dander-for-immunotherapy
#2
J P Sola, Y Pedreño, A Cerezo, M Peñalver-Mellado
BACKGROUND: Allergy to cats is a frequent cause of sensitization to indoor allergens and currently there are few alternatives to specific immunotherapy with cat native extracts. The objective is to develop and characterize a new allergoid to increase the tools available for use in clinical practice. METHODS: The allergoid cat dander extract (ACD) was developed from a native cat dander extract (NCD) by modification with glutaraldehyde, and the optimal process control was determined by SDS-PAGE, DOT BLOT and determination of free amine groups...
January 13, 2018: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/29342126/tailoring-cu-nanoparticle-catalyst-for-methanol-synthesis-using-the-spinning-disk-reactor
#3
Christian Ahoba-Sam, Kamelia V K Boodhoo, Unni Olsbye, Klaus-Joachim Jens
Cu nanoparticles are known to be very active for methanol (MeOH) synthesis at relatively low temperatures, such that smaller particle sizes yield better MeOH productivity. We aimed to control Cu nanoparticle (NP) size and size distribution for catalysing MeOH synthesis, by using the spinning disk reactor. The spinning disk reactor (SDR), which operates based on shear effect and plug flow in thin films, can be used to rapidly micro-mix reactants in order to control nucleation and particle growth for uniform particle size distribution...
January 17, 2018: Materials
https://www.readbyqxmd.com/read/29341602/polybrominated-diphenyl-ethers-polychlorinated-biphenyls-and-2-2-bis-4-chlorophenyl-1-1-dichloroethene-p-p-dde-in-7-and-9-year-old-children-and-their-mothers-in-the-chamacos-cohort
#4
Andreas Sjodin, Richard S Jones, Robert Gunier, Lee-Yang Wong, Nina T Holland, Brenda Eskenazi, Asa Bradman
We report longitudinal serum concentrations of select persistent organic pollutants in children at age seven and nine years and in their mothers prenatally and again when the children were nine years old. The participating families were enrolled in the Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS), a longitudinal birth cohort study of low income Hispanic families residing in the Salinas Valley, California. We observed decreasing concentrations in the mothers with year of serum collection (2009 vs...
January 17, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29341195/association-between-circulating-25-hydroxyvitamin-d-levels-and-psoriasis-and-correlation-with-disease-severity-a-meta-analysis
#5
Y H Lee, G G Song
BACKGROUND: Psoriasis is a chronic, autoimmune, inflammatory skin disorder. 25-hydroxy vitamin D [25(OH)D] deficiency may contribute to the pathogenesis of psoriasis through reduction in antiproliferative, anti-inflammatory and antiangiogenic activities. AIM: To evaluate the relationship between circulating 25(OH)D levels and psoriasis, and to determine the correlation between serum/plasma 25(OH)D levels and psoriasis severity. METHODS: We performed a meta-analysis to compare serum/plasma 25(OH)D levels between patients with psoriasis and healthy controls (HCs), and to determine the correlation coefficients between circulating 25(OH)D levels and psoriasis severity as assessed by Psoriasis Area and Severity Index (PASI)...
January 16, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29340749/in-pursuit-of-effective-volume-reduction-and-enhanced-aesthetics-for-treatment-of-gigantomastia-using-superior-dermoglandular-pedicle
#6
Betul Gozel Ulusal, Ince Alper
BACKGROUND: Gigantomastia is defined as extreme hypertrophy of the female breast. It is a disabling condition that presents unique challenges to plastic surgeons. Initial breast volume is an important factor affecting the success of the reduction. Usually, it is difficult to achieve small-sized breasts, and long-term results are often unsatisfactory, resulting in complications such as "bottoming-out" deformities. METHODS: This paper presents a case series involving 40 patients (mean age 44...
January 16, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29340321/randomized-clinical-trial-design-to-assess-abatacept-in-resistant-nephrotic-syndrome
#7
Howard Trachtman, Debbie S Gipson, Michael Somers, Cathie Spino, Sharon Adler, Lawrence Holzman, Jeffrey B Kopp, John Sedor, Sandra Overfield, Ayanbola Elegbe, Michael Maldonado, Anna Greka
Introduction: Treatment-resistant nephrotic syndrome is a rare form of glomerular disease that occurs in children and adults. No Food and Drug Administration-approved treatments consistently achieve remission of proteinuria and preservation of kidney function. CD80 (B7-1) can be expressed on injured podocytes, and administration of abatacept (modified CTLA4-Ig based on a natural ligand to CD80) has been associated with sustained normalization of urinary protein excretion and maintenance of glomerular filtration rate in experimental and clinical settings...
January 2018: KI Reports
https://www.readbyqxmd.com/read/29339972/evaluation-of-green-tea-extract-as-a-safe-personal-hygiene-against-viral-infections
#8
Yun Ha Lee, Yo Han Jang, Young-Seok Kim, Jinku Kim, Baik Lin Seong
Background: Viral infections often pose tremendous public health concerns as well as economic burdens. Despite the availability of vaccines or antiviral drugs, personal hygiene is considered as effective means as the first-hand measure against viral infections. The green tea catechins, in particular, epigallocatechin-3-gallate (EGCG), are known to exert potent antiviral activity. In this study, we evaluated the green tea extract as a safe personal hygiene against viral infections. Results: Using the influenza virus A/Puerto Rico/8/34 (H1N1) as a model, we examined the duration of the viral inactivating activity of green tea extract (GTE) under prolonged storage at various temperature conditions...
2018: Journal of Biological Engineering
https://www.readbyqxmd.com/read/29339655/the-impact-of-arterial-clamping-technique-in-robot-assisted-partial-nephrectomy-on-renal-function-and-surgical-outcomes-six-year-experience-at-siriraj-hospital-thailand
#9
Tawatchai Taweemonkongsap, Chalairat Suk-Ouichai, Ekkarin Chotikawanich, Siros Jitpraphai, Varat Woranisarakul, Patkawat Ramart, Kittipong Phinthusophon, Teerapon Amornvesukit, Sunai Leewansangtong, Sittiporn Srinualnad, Chaiyong Nualyong
INTRODUCTION: Robot-assisted partial nephrectomy (RAPN) with different arterial clamping techniques has increasingly been performed to avoid ischemic injury to nephron. However, postoperative renal function remains controversial. We determine the impact of each renal arterial clamping on surgical and renal outcomes after RAPN. MATERIALS AND METHODS: Patients who underwent RAPN at Siriraj Hospital from 2010 to 2016 were retrospectively reviewed and stratified into 3 cohorts: main-clamp (MAC), selective-clamp, and off-clamp...
January 16, 2018: Urologia Internationalis
https://www.readbyqxmd.com/read/29339610/effect-of-precursor-type-on-the-reduction-of-concentrated-nitrate-using-zero-valent-copper-and-sodium-borohydride
#10
Tihitinna Asmellash Belay, C Y Lin, H M Hsiao, M F Chang, J C Liu
In this study, we demonstrated that the choice of precursor has a strong effect on the reduction of nitrate (NO3-) using zero-valent copper (Cu0) synthesized by sodium borohydride (NaBH4). Different precursors: CuSO4, CuO, Cu2O, Cu powder, and Cu mesh were used to reduce NO3- at 677 mg-N/L under the reducing conditions of NaBH4. Compared with the prehydrolyzed samples, those prepared without prehydrolysis exhibited lower reduction rates, longer times and higher concentrations of nitrite (NO2-) intermediate...
January 2018: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/29339306/morphological-changes-of-bacterial-cells-upon-exposure-of-silver-silver-chloride-nanoparticles-synthesized-using-agrimonia-pilosa
#11
Maheshkumar Prakash Patil, Yong Bae Seo, Gun-Do Kim
Facile, eco-friendly synthesis of metal nanoparticles has been proposed as a cost effective method. In the present study, we propose the facile synthesis of silver-silver chloride (Ag-AgCl) nanoparticles (NPs) using the medicinally important Agrimonia pilosa plant extract without addition of capping or stabilizing agents. The Ag-AgCl NPs synthesis was observed at 40 °C after 10 min incubation; the synthesis of Ag-AgCl NPs was indicated by color change and confirmed by UV-vis spectroscopic peak at 454 nm...
January 12, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29338983/dipyridamole-plus-triflusal-versus-triflusal-alone-in-infarct-reduction-after-middle-cerebral-artery-occlusion
#12
Zareen Amtul, Wasimul Haque, David F Cechetto
BACKGROUND AND PURPOSE: The objective of this work is to study the dose-dependent effect of combination therapy with dipyridamole and triflusal over that of triflusal alone on infarct size after middle cerebral artery occlusion (MCAO) ischemia. MATERIALS AND METHODS: Male Wistar rats were subjected to a permanent MCAO in the right hemisphere. Rats received triflusal alone and with dipyridamole via oral route. Three days after surgery, infarct volumes were measured...
January 12, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29338860/learning-curve-of-image-guided-video-assisted-thoracoscopic-surgery-for-small-pulmonary-nodules-a-prospective-analysis-of-30-initial-patients
#13
Ming-Ju Hsieh, Chih-Tsung Wen, Hsin-Yueh Fang, Yu-Wen Wen, Chien-Cheng Lin, Yin-Kai Chao
OBJECTIVES: The use of image-guided video-assisted thoracoscopic surgery for simultaneous localization and removal of small solitary pulmonary nodules in a hybrid operation room using C-arm cone-beam computed tomography is gaining momentum. We sought to assess the effect of the learning curve on procedural parameters and clinical outcomes of image-guided video-assisted thoracoscopic surgery for treating patients with small solitary pulmonary nodules. METHODS: Clinical variables and treatment outcomes of the 30 initial patients with solitary pulmonary nodules who were treated with image-guided video-assisted thoracoscopic surgery at Chang Gung Memorial Hospital (Taiwan) were prospectively analyzed...
December 13, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29338856/parental-health-status-and-infant-outcomes-upstate-kids-study
#14
Germaine M Buck Louis, Erin Bell, Yunlong Xie, Rajeshwari Sundaram, Edwina Yeung
OBJECTIVE: To assess parental health status inclusive of infertility and infant outcomes. DESIGN: Birth cohort with cross-sectional analysis of parental health status and infant outcomes. SETTING: Not applicable. PATIENT(S): Parents (n = 4,886) and infants (n = 5,845) participating in the Upstate KIDS birth cohort. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Infertility was defined as [1] sexually active without contraception for 1+ years without pregnancy, [2] ever requiring ≥12 months to become pregnant, and [3] requiring ≥12 months for index pregnancy...
January 12, 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29338124/conservative-therapy-for-chalazia-is-it-really-effective
#15
Albert Y Wu, Kalla A Gervasio, Kellie N Gergoudis, Chen Wei, James H Oestreicher, John T Harvey
PURPOSE: To assess the within-treatment efficacy of hot compresses (HC), HC plus tobramycin (Tobrex) and HC plus tobramycin/dexamethasone (Tobradex) for chalazia treatment. METHODS: Design: Multicentre, randomized clinical trial (ClinicalTrials.gov identifier, NCT01230593). SETTING: Two clinical sites in New York and two clinical sites in Ontario. STUDY POPULATION: A total of 149 patients with one or more chalazia on separate eyelids randomly assigned to receive HC (n = 50), HC plus tobramycin (n = 50) or HC plus tobramycin/dexamethasone (n = 49)...
January 16, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29337857/low-molecular-weight-chitosan-insulin-complexes-solubilized-in-a-mixture-of-self-assembled-labrosol-and-plurol-oleaque-and-their-glucose-reduction-activity-in-rats
#16
Amani M Elsayed, Aseel H Khaled, Mayyas M Al Remawi, Nidal A Qinna, Hussam Abu Farsakh, Adnan A Badwan
Oral insulin delivery that better mimics physiological pathways is a necessity as it ensures patient comfort and compliance. A system which is based on a vehicle of nano order where positively charged chitosan interacts with negatively charged insulin and forms a polyelectrolyte complex (PEC) solubilizate, which is then solubilized into an oily phase of oleic acid, labrasol, and plurol oleaque-protects insulin against enzymatic gastrointestinal reduction. The use of an anionic fatty acid in the oily phase, such as oleic acid, is thought to allow an interaction with cationic chitosan, hence reducing particle size...
January 16, 2018: Marine Drugs
https://www.readbyqxmd.com/read/29336954/high-voltage-fragmentation-of-composites-from-secondary-raw-materials-potential-and-limitations
#17
T Leißner, D Hamann, L Wuschke, H-G Jäckel, U A Peuker
The comminution of composites for liberation of valuable components is a costly and energy-intensive process within the recycling of spent products. It therefore is continuously studied and optimized. In addition to conventional mechanical comminution innovative new principles for size reduction have been developed. One is the use of high voltage (HV) pulses, which is known to be a technology selectively liberating along phase boundaries. This technology offers the advantage of targeted liberation, preventing overgrinding of the material and thus improving the overall processing as well as product quality...
January 11, 2018: Waste Management
https://www.readbyqxmd.com/read/29336630/ameliorating-role-of-lycopene-tomato-puree-and-spirulina-tomato-puree-on-the-hematology-of-fluoride-exposed-swiss-albino-mice
#18
Shweta Sharma, Puneet Parashar, Subhasini Sharma, Kanta Prasad Sharma
Plant species rich in antioxidants (vitamins, flavonoids, lignans, and carotenoids) have been explored for complementary therapy of chronic diseases (cancers, coronary heart disease) and mitigation of pollutant toxicity. This article investigates their ameliorative role on selective hematological and serum biochemical parameters in fluoride-exposed (190 mg/kg body weight) Swiss albino mice pretreated with the antioxidant-rich diet supplements tomato puree (with and without peels), spirulina (cyanobacteria), and lycopene (present in tomato) for 45 days prior to entry into experimental protocol...
January 16, 2018: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29336352/one-pot-synthesis-of-ptpd-dendritic-nano-cube-cage-superstructure-on-graphenes-as-advanced-catalysts-for-oxygen-reduction
#19
Yuanyuan Zheng, Junhua Qiao, Junhua Yuan, Jianfeng Shen, Ai-Jun Wang, Peijun Gong
How to use of Pt economically and efficiently in the oxygen reduction reaction (ORR) is of theoretical and practical significance for the industrialization of the proton-exchange membrane fuel cells (PEMFCs). In order to minimize Pt consumption and optimize the ORR performance, the ORR catalysts are recommended to be designed as a porous nanostructure. Herein, we report one-pot solvothermal strategy to prepare PtPd dendritic nanocube cages via a galvanic replacement mechanism triggered by I- ion. These PtPd alloy crystals are nanoporous, and uniformly dispersed on the reduced graphene oxides (RGOs)...
January 16, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29336350/mixed-matrix-membranes-with-fast-and-selective-transport-pathways-for-efficient-co2-separation
#20
Jinpeng Hou, Xueqin Li, Ruili Guo, Jianshu Zhang, Zhongming Wang
To improve CO2 separation performance, porous carbon nanosheets (PCNs) as a filler into a Pebax MH 1657 (Pebax) matrix to fabricated mixed matrix membranes (MMMs). The PCNs exhibited a preferential horizontal orientation within the Pebax matrix because of the extremely large 2D plane and nano-scale thickness of the matrix. Therefore, the micropores of the PCNs provided fast CO2 transport pathways, which led to increased CO2 permeability. The reduced pore size of the PCNs was a consequence of the overlapping of PCNs and the polymer chains penetrate into the pores of the PCNs...
January 16, 2018: Nanotechnology
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