keyword
MENU ▼
Read by QxMD icon Read
search

Matias

keyword
https://www.readbyqxmd.com/read/28938481/vesicular-glutamate-transporter-1-knockdown-in-infralimbic-prefrontal-cortex-augments-neuroendocrine-responses-to-chronic-stress-in-male-rats
#1
Brent Myers, Jessica M McKlveen, Rachel Morano, Yvonne M Ulrich-Lai, Matia B Solomon, Steven P Wilson, James P Herman
Chronic stress-associated pathologies frequently associate with alterations in the structure and activity of medial prefrontal cortex (mPFC). However, the influence of infralimbic cortex (IL) projection neurons on HPA axis activity is unknown, as is the involvement of these cells in chronic stress-induced endocrine alterations. In the current study, a lentiviral-packaged vector coding for a small interfering RNA (siRNA) targeting vesicular glutamate transporter 1 (vGluT1) mRNA was microinjected into the IL of male rats...
July 25, 2017: Endocrinology
https://www.readbyqxmd.com/read/28935400/adjuvant-sunitinib-in-high-risk-patients-with-uveal-melanoma-comparison-with-institutional-controls
#2
Matias E Valsecchi, Marlana Orloff, Rino Sato, Inna Chervoneva, Carol L Shields, Jerry A Shields, Michael J Mastrangelo, Takami Sato
PURPOSE: To compare overall survival in high-risk patients with primary uveal melanoma who received adjuvant sunitinib with institutional controls. DESIGN: Retrospective cohort. PARTICIPANTS: Selection criteria were (1) monosomy 3 and 8q amplification by cytogenetic or DecisionDx-UM Class 2 and (2) monosomy 3 and large tumor size (T3-4 by American Joint Committee on Cancer classification). Exclusion criteria were date of diagnosis before 2007 or after 2013 and age <18 years...
September 18, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28935399/optical-coherence-tomography-biomarkers-as-functional-outcome-predictors-in-diabetic-macular-edema-treated-with-dexamethasone-implant
#3
Dinah Zur, Matias Iglicki, Catharina Busch, Alessandro Invernizzi, Miriana Mariussi, Anat Loewenstein
PURPOSE: Identification and characterization of patients with diabetic macular edema (DME) are important for individualizing treatment and optimizing outcome. We investigated optical coherence tomography (OCT) biomarkers for DME treated by intravitreal dexamethasone (DEX) implant. DESIGN: Multicenter, retrospective, observational cohort study. PARTICIPANTS: A total of 299 eyes from 284 patients treated with DEX implant for DME (naïve, n = 209; refractory, n = 90)...
September 18, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28933007/erratum-to-recommendations-for-biomarker-testing-in-epithelial-ovarian-cancer-a-national-consensus-statement-by-the-spanish-society-of-pathology-and-the-spanish-society-of-medical-oncology
#4
A Oaknin, R Guarch, P Barretina, D Hardisson, A González-Martín, X Matías-Guiu, A Pérez-Fidalgo, B Vieites, I Romero, J Palacios
No abstract text is available yet for this article.
September 20, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/28929981/the-presence-of-acylated-ghrelin-during-in-vitro-maturation-of-bovine-oocytes-induces-cumulus-cell-dna-damage-and-apoptosis-and-impairs-early-embryo-development
#5
Matias A Sirini, Juan Mateo Anchordoquy, Juan Patricio Anchordoquy, Ana M Pascua, Noelia Nikoloff, Ana Carranza, Alejandro E Relling, Cecilia C Furnus
The aim of this study was to investigate the effects of acylated ghrelin supplementation during in vitro maturation (IVM) of bovine oocytes. IVM medium was supplemented with 20, 40 or 60 pM acylated ghrelin concentrations. Cumulus expansion area and oocyte nuclear maturation were studied as maturation parameters. Cumulus-oocyte complexes (COC) were assessed with the comet, apoptosis and viability assays. The in vitro effects of acylated ghrelin on embryo developmental capacity and embryo quality were also evaluated...
September 20, 2017: Zygote: the Biology of Gametes and Early Embryos
https://www.readbyqxmd.com/read/28929761/the-reaction-of-methyl-fluoroformyl-peroxycarbonate-fc-o-ooc-o-och3-with-cl-atoms-formation-of-hydro-chlorofluoro-peroxides
#6
Matias Berasategui, Gustavo Alejandro Argüello, Maxi Alberto Burgos Paci
The products following Cl atom initiated reactions of FC(O)OOC(O)OCH3 in 50-760 Torr of N2 at 296 K were investigated using FTIR. Reaction of Cl atoms with methyl fluoroformyl peroxycarbonate proceeds mainly via attack at the methyl group, forming FC(O)OOC(O)OCH2˙ radicals. Further reaction of this kind of radicals with Cl2 forms three new compounds: FC(O)OOC(O)OCH2Cl; FC(O)OOC(O)OCHCl2 and FC(O)OOC(O)OCCl3, whose existence was characterized experimentally by FTIR spectroscopy assisted with ab-initio calculations at the B3LYP/6-31++G(d,p) level...
September 20, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28926836/percutaneous-biliary-balloon-dilation-impact-of-an-institutional-three-session-protocol-on-patients-with-benign-anastomotic-strictures-of-hepatojejunostomy
#7
Matias E Czerwonko, Pablo Huespe, Oscar Mazza, Martin de Santibanes, Rodrigo Sanchez-Claria, Juan Pekolj, Miguel Ciardullo, Eduardo de Santibanes, Sung Ho Hyon
BACKGROUND: Percutaneous biliary balloon dilation (PBBD) stands as a safe, useful, and inexpensive treatment procedure performed on patients with benign anastomotic stricture of Roux-en-Y hepatojejunostomy (BASH). However, the optimal mode of application is still under discussion. METHODS: A retrospective cohort study was conducted including patients admitted between 2008 and 2015 with diagnosis of BASH. Patients were divided into 2 groups: group I (n = 22), included patients treated after the implementation of an institutional protocol of 3 PBBD sessions within a fixed time interval and group II (n = 24) consisted of our historical control of patients who underwent one or 2 dilation sessions...
September 20, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28926330/-diabetes-socioeconomic-inequalities-in-the-portuguese-population-in-2014
#8
Joana Santos, Irina Kislaya, Liliana Antunes, Ana João Santos, Ana Paula Paula Rodrigues, Mariana Neto, Carlos Matias Dias
INTRODUCTION: Diabetes is a major public health problem and it is related to socioeconomic factors. The aim of this study is to describe socioeconomic inequalities in the distribution of diabetes in the population with 25 years or more, resident in Portugal in 2014. MATERIAL AND METHODS: Data from the Health National Survey 2014 was analysed, n = 16 786. We estimated the prevalence of diabetes in the population and stratified by socioeconomic variables namely educational level and income...
August 31, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28926120/glecaprevir-pibrentasvir-for-hcv-genotype-3-patients-with-cirrhosis-and-or-prior-treatment-experience-a-partially-randomized-phase-iii-clinical-trial
#9
David Wyles, Fred Poordad, Stanley Wang, Laurent Alric, Franco Felizarta, Paul Y Kwo, Benedict Maliakkal, Kosh Agarwal, Tarek Hassanein, Frank Weilert, Samuel S Lee, Jens Kort, Sandra S Lovell, Ran Liu, Chih-Wei Lin, Tami Pilot-Matias, Preethi Krishnan, Federico J Mensa
BACKGROUND: This study assessed the efficacy and safety of ribavirin (RBV)-free coformulated glecaprevir/pibrentasvir (G/P) in patients with hepatitis C virus (HCV) genotype (GT) 3 infection with either prior treatment experience and/or compensated cirrhosis, a patient population with limited treatment options. METHODS: SURVEYOR-II, Part 3 was a partially-randomized, open-label, multicenter, phase 3 study. Treatment-experienced (prior interferon (IFN) or pegIFN ± ribavirin or SOF plus ribavirin ± pegIFN therapy) patients without cirrhosis were randomized 1:1 to receive 12 or 16 weeks of G/P (300 mg/120 mg) once daily...
September 19, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28922535/power-and-coherence-of-cortical-high-frequency-oscillations-during-wakefulness-and-sleep
#10
Matías Cavelli, Daniel Rojas-Líbano, Natalia Schwarzkopf, Santiago Castro-Zaballa, Joaquín Gonzalez, Alejandra Mondino, Noelia Santana, Luciana Benedetto, Atilio Falconi, Pablo Torterolo
Recently, a novel type of fast cortical oscillatory activity that occurs between 110 and 160 Hz (high-frequency oscillations (HFO)) was described. HFO are modulated by the theta rhythm in hippocampus and neocortex during active wakefulness and REM sleep. Since theta-HFO coupling increases during REM, a role for HFO in memory consolidation has been proposed. However, global properties like the cortex-wide topographic distribution, and the cortico-cortical coherence remain unknown. In the present study, we recorded the electroencephalogram during sleep and wakefulness in the rat, and analyzed the spatial extent of the HFO band power and coherence...
September 18, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28916268/prevalence-of-overweight-and-obesity-in-portugal-results-from-the-first-portuguese-health-examination-survey-insef-2015
#11
Vânia Gaio, Liliana Antunes, Sónia Namorado, Marta Barreto, Ana Gil, Irina Kyslaya, Ana Paula Rodrigues, Ana Santos, Linn Bøhler, Emília Castilho, Patrícia Vargas, Isabel do Carmo, Baltazar Nunes, Carlos Matias Dias
Obesity is recognised as a serious public health issue, due to its associated morbidity and mortality. This study aimed at estimating the prevalence of overweight and obesity in the Portuguese population through direct measurements obtained by the 1st National Health Examination Survey (INSEF 2015) and to identify its associated sociodemographic factors. INSEF was a nationally representative cross-sectional prevalence study conducted on 4911 Portuguese adults aged 25-74 years, in 2015. Height and weight were measured according to the European Health Examination Survey procedures...
September 12, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28916247/comparison-of-two-control-groups-for-estimation-of-oral-cholera-vaccine-effectiveness-using-a-case-control-study-design
#12
Molly F Franke, J Gregory Jerome, Wilfredo R Matias, Ralph Ternier, Isabelle J Hilaire, Jason B Harris, Louise C Ivers
BACKGROUND: Case-control studies to quantify oral cholera vaccine effectiveness (VE) often rely on neighbors without diarrhea as community controls. Test-negative controls can be easily recruited and may minimize bias due to differential health-seeking behavior and recall. We compared VE estimates derived from community and test-negative controls and conducted bias-indicator analyses to assess potential bias with community controls. METHODS: From October 2012 through November 2016, patients with acute watery diarrhea were recruited from cholera treatment centers in rural Haiti...
September 12, 2017: Vaccine
https://www.readbyqxmd.com/read/28915867/the-associations-between-workplace-bullying-salivary-cortisol-and-long-term-sickness-absence-a-longitudinal-study
#13
Matias Brødsgaard Grynderup, Kirsten Nabe-Nielsen, Theis Lange, Paul Maurice Conway, Jens Peter Bonde, Anne Helene Garde, Maria Gullander, Linda Kaerlev, Roger Persson, Reiner Rugulies, Marianne Agergaard Vammen, Annie Høgh, Åse Marie Hansen
BACKGROUND: Workplace stressors, such as bullying, are strongly related to subsequent long-term sickness absence, but little is known of the possible physiological mechanisms linking workplace stressors and sickness absence. The primary aim of this study was to investigate to what extent cortisol levels were associated with subsequent sickness absence and if cortisol mediated the association between workplace bullying and sickness absence. We additionally investigated possible bidirectional associations between bullying, cortisol, and long-term sickness absence...
September 16, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28915517/biallelic-mutations-in-slc1a2-an-additional-mode-of-inheritance-for-slc1a2-related-epilepsy
#14
Matias Wagner, Mirjana Gusic, Roman Günthner, Bader Alhaddad, Reka Kovacs-Nagy, Christine Makowski, Friedrich Baumeister, Tim Strom, Thomas Meitinger, Holger Prokisch, Saskia B Wortmann
No abstract text is available yet for this article.
September 15, 2017: Neuropediatrics
https://www.readbyqxmd.com/read/28915449/increased-expression-of-nlrp3-inflammasome-in-placentas-from-pregnant-women-with-severe-preeclampsia
#15
Ingrid C Weel, Mariana Romão-Veiga, Mariana L Matias, Eduardo G Fioratti, Jose C Peraçoli, Vera T Borges, João P Araujo, Maria T Peraçoli
Preeclampsia is a pregnancy disorder characterized by imbalance between pro- and anti-inflammatory cytokines associated with high plasma levels of uric acid and Interleukin-1 beta (IL-1β). The inflammasome is a protein complex that mediates innate immune responses via caspase-1 activation promoting secretion of IL-1β and IL-18 in their active forms, and also release of the high-mobility group box 1 protein (HMGB1). As the placenta seems to play an important role in the pathogenesis of PE, the present study investigated the expression of genes and proteins related to the inflammasome in placentas from pregnant women with severe preeclampsia...
September 6, 2017: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/28905157/landscape-genetics-in-the-subterranean-rodent-ctenomys-chasiquensis-associated-with-highly-disturbed-habitats-from-the-southeastern-pampas-region-argentina
#16
Matías Sebastián Mora, Fernando J Mapelli, Aldana López, María Jimena Gómez Fernández, Patricia M Mirol, Marcelo J Kittlein
Studies of genetic differentiation in fragmented environments help us to identify those landscape features that most affect gene flow and dispersal patterns. Particularly, the assessment of the relative significance of intrinsic biological and environmental factors affecting the genetic structure of populations becomes crucial. In this work, we assess the current dispersal patterns and population structure of Ctenomys "chasiquensis", a vulnerable and endemic subterranean rodent distributed on a small area in Central Argentina, using 9 polymorphic microsatellite loci...
September 13, 2017: Genetica
https://www.readbyqxmd.com/read/28902894/what-determines-sclerobiont-colonization-on-marine-mollusk-shells
#17
Vanessa Ochi Agostini, Matias do Nascimento Ritter, Alexandre José Macedo, Erik Muxagata, Fernando Erthal
Empty mollusk shells may act as colonization surfaces for sclerobionts depending on the physical, chemical, and biological attributes of the shells. However, the main factors that can affect the establishment of an organism on hard substrates and the colonization patterns on modern and time-averaged shells remain unclear. Using experimental and field approaches, we compared sclerobiont (i.e., bacteria and invertebrate) colonization patterns on the exposed shells (internal and external sides) of three bivalve species (Anadara brasiliana, Mactra isabelleana, and Amarilladesma mactroides) with different external shell textures...
2017: PloS One
https://www.readbyqxmd.com/read/28886858/trends-and-impact-of-door-to-balloon-time-on-clinical-outcomes-in-patients-aged-75-75-to-84-and-%C3%A2-85-years-with-st-elevation-myocardial-infarction
#18
Matias B Yudi, Garry Hamilton, Omar Farouque, Nick Andrianopoulos, Stephen J Duffy, Jeffrey Lefkovits, Angela Brennan, Dharsh Fernando, Chin Hiew, Melanie Freeman, Christopher M Reid, Robynne Dakis, Andrew E Ajani, David J Clark
Guidelines strongly recommend patients with ST-elevation myocardial infarction (STEMI) receive timely mechanical reperfusion, defined as door-to-balloon time (DTBT) ≤90 minutes. The impact of timely reperfusion on clinical outcomes in patients aged 75-84 and ≥85 years is uncertain. We analysed 2,972 consecutive STEMI patients who underwent primary percutaneous coronary intervention from the Melbourne Interventional Group Registry (2005-2014). Patients aged <75 years were included in the younger group, those aged 75-84 years were in the elderly group and those ≥85 years were in the very elderly group...
July 28, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28886341/cdk10-mutations-in-humans-and-mice-cause-severe-growth-retardation-spine-malformations-and-developmental-delays
#19
Christian Windpassinger, Juliette Piard, Carine Bonnard, Majid Alfadhel, Shuhui Lim, Xavier Bisteau, Stéphane Blouin, Nur'Ain B Ali, Alvin Yu Jin Ng, Hao Lu, Sumanty Tohari, S Zakiah A Talib, Noémi van Hul, Matias J Caldez, Lionel Van Maldergem, Gökhan Yigit, Hülya Kayserili, Sameh A Youssef, Vincenzo Coppola, Alain de Bruin, Lino Tessarollo, Hyungwon Choi, Verena Rupp, Katharina Roetzer, Paul Roschger, Klaus Klaushofer, Janine Altmüller, Sudipto Roy, Byrappa Venkatesh, Rudolf Ganger, Franz Grill, Farid Ben Chehida, Bernd Wollnik, Umut Altunoglu, Ali Al Kaissi, Bruno Reversade, Philipp Kaldis
In five separate families, we identified nine individuals affected by a previously unidentified syndrome characterized by growth retardation, spine malformation, facial dysmorphisms, and developmental delays. Using homozygosity mapping, array CGH, and exome sequencing, we uncovered bi-allelic loss-of-function CDK10 mutations segregating with this disease. CDK10 is a protein kinase that partners with cyclin M to phosphorylate substrates such as ETS2 and PKN2 in order to modulate cellular growth. To validate and model the pathogenicity of these CDK10 germline mutations, we generated conditional-knockout mice...
September 7, 2017: American Journal of Human Genetics
https://www.readbyqxmd.com/read/28884495/asymmetrical-size-and-functionality-of-the-pampas-deer-ozotoceros-bezoarticus-testes-right-testis-is-bigger-but-left-testis-is-more-efficient-in-spermatogenesis
#20
Rodolfo Ungerfeld, Matías Villagrán, Lorena Lacuesta, Noelia Vazquez, William Pérez
Information about gonadal asymmetries in ruminants is very scarce. In this work, we performed three complementary studies to compare characteristics of both testes: (i) weight and size of offspring and adult dead males; (ii) the tissue:fluid relationship determined by ultrasound scanning; and (iii) the spermatogenic status using fine needle aspiration cytology. The right testis was heavier than the left one in both offspring and adult animals and had greater width and volume in adult males than the left one...
September 7, 2017: Anatomia, Histologia, Embryologia
keyword
keyword
24894
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"