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Nerve conduction study

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https://www.readbyqxmd.com/read/29775143/testing-the-effectiveness-and-the-contribution-of-experimental-supercharge-reversed-end-to-side-nerve-transfer
#1
Mustafa Nadi, Sudheesh Ramachandran, Abir Islam, Joanne Forden, Gui Fang Guo, Rajiv Midha
OBJECTIVE Supercharge end-to-side (SETS) transfer, also referred to as reverse end-to-side transfer, distal to severe nerve compression neuropathy or in-continuity nerve injury is gaining clinical popularity despite questions about its effectiveness. Here, the authors examined SETS distal to experimental neuroma in-continuity (NIC) injuries for efficacy in enhancing neuronal regeneration and functional outcome, and, for the first time, they definitively evaluated the degree of contribution of the native and donor motor neuron pools...
May 18, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29774175/motor-interconnections-between-superior-and-inferior-laryngeal-nerves
#2
Emin Gurleyik
Introduction Anatomical studies on human cadavers have established anastomoses between laryngeal nerves. However, we need to functionally identify motor communication via these anastomoses between the recurrent laryngeal nerve (RLN) and the external branch of the superior laryngeal nerve (EBSLN) in living bodies. We aim to establish motor interconnections using intraoperative nerve monitoring (IONM). Methods IONM of 112 EBSLNs and RLNs in 62 thyroidectomy cases was used to establish motor functions of laryngeal nerves...
March 16, 2018: Curēus
https://www.readbyqxmd.com/read/29773852/protective-effects-of-intraoperative-nerve-monitoring-ionm-for-recurrent-laryngeal-nerve-injury-in-thyroidectomy-meta-analysis
#3
Binglong Bai, Wuzhen Chen
Recurrent laryngeal nerve (RLN) injury is an intractable complication of thyroidectomy. Intraoperative nerve monitoring (IONM) was designed to prevent RLN injury. However, the results concerning the protective effect of IONM on RLN injury are still controversial. We searched all eligible databases from 1980 to 2017. Meta-analysis was performed to evaluate the effect of IONM on RLN injury. Sensitivity analysis was also conducted to check the stability of our results. There were 34 studies included in the analysis...
May 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29770208/case-report-polyarteritis-nodosa-or-complicated-henoch-schonlein-purpura-a-rare-case
#4
Sajad Hasanzadeh, Seyedeh Maryam Alavi, Elahe Masnavi, Maryam Rohani, Saeid Jokar
Background: Polyarteritis nodosa (PAN) is a vasculitis that affects medium sized arteries. PAN is a rare disease and requires a high vilgilance for diagnosis. For instance, PAN and Henoch-Schonlein purpura (HSP) have narrowing differential diagnosis. Here, we report a case of PAN. Case presentation : Our patient was a 65 year old woman that came to hospital due to abdominal pain and skin lesion on the right upper and right lower extremities. All rheumatologic tests were negative. A biopsy of the skin lesion was reported as mild hyperkeratosis, slight spongiosis with intact basal layer...
2018: F1000Research
https://www.readbyqxmd.com/read/29768985/effects-of-monoclonal-antibodies-against-nerve-growth-factor-on-healthy-bone-and-joint-tissues-in-mice-rats-and-monkeys-histopathologic-biomarker-and-microcomputed-tomographic-assessments
#5
Kathryn E Gropp, Cathy S Carlson, Mark G Evans, Cedo M Bagi, William J Reagan, Susan I Hurst, David L Shelton, Mark A Zorbas
Tanezumab, an anti-nerve growth factor (NGF) antibody, is in development for management of chronic pain. During clinical trials of anti-NGF antibodies, some patients reported unexpected adverse events requiring total joint replacements, resulting in a partial clinical hold on all NGF inhibitors. Three nonclinical toxicology studies were conducted to evaluate the effects of tanezumab or the murine precursor muMab911 on selected bone and joint endpoints and biomarkers in cynomolgus monkeys, Sprague-Dawley rats, and C57BL/6 mice...
January 1, 2018: Toxicologic Pathology
https://www.readbyqxmd.com/read/29766936/risk-factors-symptom-severity-and-functional-status-among-patients-with-carpel-tunnel-syndrome
#6
F Sharief, J Kanmani, S Kumar
Background: Carpal tunnel syndrome refers to a constellation of symptoms resulting from compression of the median nerve at the wrist. The characteristic symptoms include pain and numbness in the hands. Aim: To identify the risk factors responsible for carpal tunnel syndrome, to identify the symptom severity as well as functional status of patients with carpal tunnel syndrome, and to determine the relationship between symptom severity and functional status among patients with carpal tunnel syndrome...
May 2018: Neurology India
https://www.readbyqxmd.com/read/29765886/reference-value-for-infrapatellar-branch-of-saphenous-nerve-conduction-study-cadaveric-and-clinical-study
#7
Keon-Tae Kim, Yong-Ki Kim, Jung Ro Yoon, Yundam Ko, Myung Eun Chung
Objective: To determine the optimal stimulation and recording site for infrapatellar branch of saphenous nerve (IPBSN) conduction studies by a cadaveric study, and to confirm that obtained location is practically applicable to healthy adults. Methods: Twelve lower limbs from six cadavers were studied. We defined the optimal stimulation site as the point IPBSN exits the sartorius muscle and the distance or ratio were measured on the X- and Y-axis based on the line connecting the medial and lateral poles of the patella...
April 2018: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29765874/predictive-variables-for-sonographically-guided-corticosteroid-injection-in-mild-to-moderate-carpal-tunnel-syndrome
#8
Seong Yun Chung, Jung Min Kwak, Seok Kang, Seong-Ho Son, Jae Do Kim, Joon Shik Yoon
Objective: To assess the predictive variables after sonographically guided corticosteroid injection in carpal tunnel syndrome. Methods: A prospective, observational study was carried out on 25 wrists of 20 consecutive patients with carpal tunnel syndrome, confirmed by the American Association of Neuromuscular and Electrodiagnostic Medicine criteria, which includes clinical history, symptoms, and evidence of slowing of distal median nerve conduction. Visual analogue scale (VAS) and Boston Carpal Tunnel Questionnaire (BCTQ) were asked to the patients before and 4 weeks after the procedure...
April 2018: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29765578/lipid-lowering-drugs-statins-and-peripheral-neuropathy
#9
Mohammadreza Emad, Hosein Arjmand, Hamid Reza Farpour, Bahareh Kardeh
Background and aim: Peripheral neuropathy is a disorder with often unknown causes. Some drugs, including statins, are proposed to be among the causes of peripheral neuropathy. This study aimed at evaluating this condition by electrodiagnostic study among patients who had received statins. Methods: This case-control study was conducted in Shiraz, Iran in 2015, and included 39 patients aged 35-55 who had received statins for at least 6 months, and 39 healthy matched controls...
March 2018: Electronic Physician
https://www.readbyqxmd.com/read/29765199/the-development-of-a-reference-database-with-the-topcon-3d-oct-1-maestro
#10
Michael Chaglasian, Murray Fingeret, Pinakin Gunvant Davey, Wei-Chieh Huang, Danny Leung, Edmund Ng, Charles A Reisman
Importance: The paper presents the range for measurements taken with a new spectral domain optical coherence tomography (OCT) device to establish a reference database for discrimination purposes. Objective: To report the range of thickness values for the new Topcon Maestro 3D OCT device with 2 scan size settings: the 12×9 mm wide field and 6×6 mm scans. Design: Prospective, multicenter cohort study conducted at 7 clinical sites across the USA...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29761130/spinal-muscular-atrophy-with-respiratory-distress-type-1-a-child-with-atypical-presentation
#11
Annie Ting Gee Chiu, Sophelia Hoi Shan Chan, Shun Ping Wu, Shun Hin Ting, Brian Hon Yin Chung, Angel On Kei Chan, Virginia Chun Nei Wong
The authors report a child with spinal muscular atrophy with respiratory distress type 1 (SMARD1). She presented atypically with hypothyroidism and heart failure due to septal defects that required early heart surgery and microcephaly in association with cerebral atrophy and thin corpus collosum. The subsequent asymmetrical onset of diaphragmatic paralysis, persistent hypotonia, and generalized muscle weakness led to the suspicion of spinal muscular atrophy with respiratory distress type 1. Sanger sequencing confirmed a compound heterozygous mutation in the Immunoglobulin Mu Binding Protein 2 (IGHMBP2) gene, with a known mutation c...
2018: Child Neurology Open
https://www.readbyqxmd.com/read/29761123/zika-virus-and-guillain-barr%C3%A3-syndrome-in-bangladesh
#12
Corine H GeurtsvanKessel, Zhahirul Islam, Md Badrul Islam, Sandra Kamga, Nowshin Papri, David A M C van de Vijver, Chantal Reusken, Ramona Mogling, Astrid P Heikema, Israt Jahan, Florence K Pradel, Rebecca L Pavlicek, Quazi D Mohammad, Marion P G Koopmans, Bart C Jacobs, Hubert P Endtz
Objective: Previous studies have associated Guillain-Barré syndrome (GBS) with Zika virus (ZIKV) outbreaks in South America and Oceania. In Asia, ZIKV is known to circulate widely, but the association with Guillain-Barré syndrome is unclear. We investigated whether endemic ZIKV infection is associated with the development of GBS. Methods: A prospective study was conducted from 2011 to 2015 in Bangladesh. A total of 418 patients and 418 healthy family controls were included in the study...
May 2018: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/29758078/the-provision-of-written-information-and-its-effect-on-levels-of-pain-and-anxiety-during-electrodiagnostic-studies-a-randomised-controlled-trial
#13
Yan Ling Lai, Annemarie Van Heuven, Adeniyi Borire, Tejaswi Kandula, James G Colebatch, Arun V Krishnan, William Huynh
OBJECTIVE: The provision of written information is a low-cost and readily available intervention that has been found to reduce pain and anxiety in a variety of clinical settings. The current study was undertaken to determine if information provision may improve patients' experience during conventional electrodiagnostic studies. METHODS: 128 participants were recruited from a tertiary teaching hospital who were referred for electrodiagnostic studies. They were randomized into 2 groups where the intervention group was provided with written information about the electrodiagnostic testing...
2018: PloS One
https://www.readbyqxmd.com/read/29757410/chronic-kidney-disease-and-peripheral-nerve-function-in-the-health-aging-and-body-composition-study
#14
Ranjani N Moorthi, Simit Doshi, Linda F Fried, Sharon M Moe, Mark J Sarnak, Suzanne Satterfield, Ann V Schwartz, Michael Shlipak, Brittney S Lange-Maia, Tamara B Harris, Anne B Newman, Elsa S Strotmeyer
Background: Chronic kidney disease (CKD) is associated with poor mobility. Peripheral nerve function alterations play a significant role in low mobility. We tested the hypothesis that early CKD is associated with altered sensory, motor and autonomic nerve function. Methods: Participants in the Health, Aging and Body Composition cohort who had kidney function measures in Year 3 (1999-2000) and nerve function measurements at Year 4 (2000-01) were analyzed (n = 2290)...
May 10, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29756608/nerve-and-vein-preserving-neck-dissections-for-oral-cancers-a-prospective-evaluation-of-spinal-accessory-nerve-function-and-internal-jugular-vein-patency-following-treatment
#15
G R Kumar Reddy, N Hulikal, A Y Lakshmi, B Vengamma
Nerve and vein preserving modification of the radical neck dissection is commonly used in the management of oral squamous cell cancers. There is limited literature addressing nerve function and vein patency following treatment. We prospectively analysed 65 patients with nerve conduction study using surface electromyography at baseline, 1 month and 6 months post-surgery and colour Doppler of the internal jugular vein at baseline and 1 month post-surgery. We also studied functional outcomes of nerve sparing with arm abduction test and Neck Dissection Quality of Life questionnaire...
February 2018: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29756164/methods-for-the-determination-of-skeletal-muscle-blood-flow-development-strengths-and-limitations
#16
REVIEW
Lasse Gliemann, Stefan P Mortensen, Ylva Hellsten
Since the first measurements of limb blood flow at rest and during nerve stimulation were conducted in the late 1800s, a number of methods have been developed for the determination of limb and skeletal muscle blood flow in humans. The methods, which have been applied in the study of aspects such as blood flow regulation, oxygen uptake and metabolism, differ in terms of strengths and degree of limitations but most have advantages for specific settings. The purpose of this review is to describe the origin and the basic principles of the methods, important aspects and requirements of the procedures...
May 14, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29750309/knockdown-of-ran-gtpase-expression-inhibits-the-proliferation-and-migration-of-breast-cancer-cells
#17
Chenyi Sheng, Jian Qiu, Yingying Wang, Zhixian He, Hua Wang, Qingqing Wang, Yeqing Huang, Lianxin Zhu, Feng Shi, Yingying Chen, Shiyao Xiong, Zhen Xu, Qichao Ni
Breast cancer is the second leading cause of cancer‑associated mortality in women worldwide. Strong evidence has suggested that Ran, which is a small GTP binding protein involved in the transport of RNA and protein across the nucleus, may be a key cellular protein involved in the metastatic progression of cancer. The present study investigated Ran gene expression in breast cancer tissue samples obtained from 140 patients who had undergone surgical resection for breast cancer. Western blot analysis of Ran in breast cancer tissues and paired adjacent normal tissues showed that expression of Ran was significantly increased in breast cancer tissues...
May 3, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29749662/high-resolution-nerve-ultrasound-and-electrophysiological-findings-in-restless-legs-syndrome
#18
K Pitarokoili, M Fels, A Kerasnoudis, L Toenges, R Gold, M-S Yoon
BACKGROUND AND PURPOSE: Restless legs syndrome (RLS) is a multifactorial network disorder of a sensorimotor system extending from dopaminergic and glutamatergic cerebral structures to the spinal neurons and peripheral nerves. The role of peripheral nerve damage in the causality and severity progression for RLS patients remains unclear. METHODS: We performed a clinical and epidemiological study on a cohort of 34 RLS patients focusing on RLS risk factors and disease severity...
May 11, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29747821/gangliosides-in-axon-stability-and-regeneration
#19
Pablo H H Lopez, Bárbara Beatriz Báez
Gangliosides are a family of sialic acid-containing glycosphingolipids highly expressed in the nervous system of vertebrates. Over the last 25years, research has unmasked several of their neurobiological functions but the role of gangliosides in the nervous system remains not fully elucidated. Genetic disruption of genes for key enzymes involved in ganglioside biosynthesis led to the discovery of their diverse functions and highlighted the exquisite structural specificity required in this processes. In the nervous system, gangliosides regulate axonal caliber and organize ion channels at the nodes of Ranvier, a critical step to ensure fast conduction velocity of myelinated fibers...
2018: Progress in Molecular Biology and Translational Science
https://www.readbyqxmd.com/read/29746515/variations-of-the-origin-of-superior-thyroid-artery-and-its-relationship-with-the-external-branch-of-superior-laryngeal-nerve
#20
Meselech Ambaw Dessie
INTRODUCTION: The superior thyroid artery, the main atrial supply of neck region, is branched from the external carotid artery as a first branch, but it may also arise from the common carotid artery and its bifurcation. The external branch of superior laryngeal nerve runs parallel to it and later crossing the artery either above or below the upper pole of the thyroid gland. OBJECTIVE: This study aimed at evaluating the variations of the origin of superior thyroid artery and its relationship with the external branch of the superior laryngeal nerve...
2018: PloS One
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