keyword
https://read.qxmd.com/read/38706565/untargeted-metabolomics-based-on-ultra-high-performance-liquid-chromatography-mass-spectrometry-ms-reveals-the-lipid-lowering-mechanism-of-taurine-in-hyperlipidemia-mice
#1
JOURNAL ARTICLE
Xinzhe Guo, Tong Ou, Xinyu Yang, Qi Song, Lin Zhu, Shengquan Mi, Jing Zhang, Yanzhen Zhang, Wen Chen, Junxia Guo
INTRODUCTION: Taurine has a prominent lipid-lowering effect on hyperlipidemia. However, a comprehensive analysis of the effects of taurine on endogenous metabolites in hyperlipidemia has not been documented. This study aimed to explore the impact of taurine on multiple metabolites associated with hyperlipidemia. METHODS: The hyperlipidemic mouse model was induced by high-fat diet (HFD). Taurine was administered via oral gavage at doses of 700  mg/kg/day for 14  weeks...
2024: Frontiers in Nutrition
https://read.qxmd.com/read/38706152/lipids-as-biomarkers-to-assess-the-nutritional-and-physiological-status-of-two-diadromous-fish-anguilla-anguilla-and-chelon-auratus-at-early-life-stages-in-a-temperate-macrotidal-estuary
#2
JOURNAL ARTICLE
Elorri Arevalo, Nicolas Mazzella, Henrique N Cabral, Aurélie Moreira, Gwilherm Jan, Bertrand Villeneuve, Carl Possémé, Mario Lepage
Estuaries are considered as key habitats for the early life stages of fish. However, in the face of massive destruction of many estuarine intertidal areas, management and conservation measures are needed. Fish condition indicators may be used as a proxy of habitat quality and provide valuable information for management of coastal areas. In this study, the larvae of golden mullet (Chelon auratus) and European glass eels (Anguilla anguilla) were sampled in three sites of the Gironde Estuary. Different lipid classes and fatty acids were quantified: phospholipids (globally, phosphatidylethanolamine and phosphatidylcholine), triglycerides, omega-3 (particularly docosahexaenoic and eicosapentaenoic acids), omega-6 and C18:1...
May 5, 2024: Journal of Fish Biology
https://read.qxmd.com/read/38704922/the-dynamics-of-nitrous-oxide-and-methane-emissions-from-various-types-of-dairy-manure-at-smallholder-dairy-farms-as-affected-by-storage-periods
#3
JOURNAL ARTICLE
Windi Al Zahra, Mohammad Ikhsan Shiddieqy, Rahma Anisa, Ahmad Yani, Bagus Priyo Purwanto
Storing manure emits greenhouse gas (GHG) emissions, including nitrous oxide (N2 O) and methane (CH4 ). However, the emissions from types of manure stored at smallholder dairy farms remains unknown. Hence, the study aims to analyse the dynamics of N2 O and CH4 from different types of dairy manure as affected by storage periods. We collected samples from fresh manure (FM-DF1), manure from communal ponds in an urban dairy farm (IP-DF1, FP-DF1, MS-DF1), fresh manure from an urban dairy farm (FM-DF2), and fresh (FM-DF3), separated (FS-DF3), and fermented manure (FR-DF3) from a peri-urban dairy farm, and stored them for eight weeks and analyse them using the closed chamber method...
May 4, 2024: Waste Management
https://read.qxmd.com/read/38698458/microbiome-composition-and-presence-of-cultivable-commensal-groups-of-southern-tamanduas-tamandua-tetradactyla-varies-with-captive-conditions
#4
JOURNAL ARTICLE
Ahmad Amin, Chahrazed Mekadim, Nikol Modrackova, Petra Bolechova, Jakub Mrazek, Vera Neuzil-Bunesova
Southern Tamanduas (Tamandua tetradactyla) belong to the specialized placental myrmecophages. There is not much information about their intestinal microbiome. Moreover, due to their food specialization, it is difficult to create an adequate diet under breeding conditions. Therefore, we used 16S rDNA amplicon sequencing to analyze the fecal microbiome of captive Southern Tamanduas from four locations in the Czech Republic and evaluated the impact of the incoming diet and facility conditions on microbiome composition...
May 2, 2024: Animal microbiome
https://read.qxmd.com/read/38698454/lifestyle-management-and-brain-mri-metrics-in-female-australian-adults-living-with-multiple-sclerosis-a-feasibility-and-acceptability-study
#5
JOURNAL ARTICLE
Olivia Wills, Brooklyn Wright, Lisa-Marie Greenwood, Nadia Solowij, Mark Schira, Jerome J Maller, Alok Gupta, John Magnussen, Yasmine Probst
BACKGROUND: Limited studies of multiple sclerosis (MS) exist whereby magnetic resonance imaging (MRI) of the brain with consistent imaging protocols occurs at the same time points as collection of healthy lifestyle measures. The aim of this study was to test the feasibility, acceptability and preliminary efficacy of acquiring MRI data as an objective, diagnostic and prognostic marker of MS, at the same time point as brain-healthy lifestyle measures including diet. METHODS: Participants living with relapsing remitting MS partook in one structural MRI scanning session of the brain, completed two online 24-hour dietary recalls and demographic and self-reported lifestyle questionnaires (e...
May 2, 2024: Pilot and Feasibility Studies
https://read.qxmd.com/read/38694991/the-prevalence-and-its-associated-factors-of-psychological-stress-among-middle-school-students-in-china-pooled-evidence-from-a-systematic-scoping-review
#6
JOURNAL ARTICLE
Li Hao, Arimi Fitri Mat Ludin, Mahadir Ahmad, Xie Meng, He Zhong Lei
UNLABELLED: Psychological issues are of significant concern in present-day society, as poor mental well-being results in depression and suicidal behavior. Understanding the current situation of psychological stress among secondary school students will help policy makers to formulate targeted measures to help them cope with stress, and at the same time evaluate the effectiveness of the existing policies to address the shortcomings and enhance the diversification of interventions. The main purpose of this review was to map the existing evidence on the prevalence and levels of psychological stress among adolescents in China, and to identify the associated risk factors...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38686837/culinary-medicine-experiences-for-medical-students-and-residents-in-the-u-s-and-canada-a-scoping-review
#7
JOURNAL ARTICLE
Caitlin A Hildebrand, Meghana B Patel, Alyssa B Tenney, Julia A Logan, Khanh H Luong, Miranda J Crouch, Amanda E Osta, Courtney DeRoo, Kurt O Gilliland, Timothy S Harlan, Alice S Ammerman
PHENOMENON: Despite the importance of diet in the prevention and management of many common chronic diseases, nutrition training in medicine is largely inadequate in medical school and residency. The emerging field of culinary medicine offers an experiential nutrition learning approach with the potential to address the need for improved nutrition training of physicians. Exploring this innovative nutrition training strategy, this scoping review describes the nature of culinary medicine experiences for medical students and resident physicians, their impact on the medical trainees, and barriers and facilitators to their implementation...
April 30, 2024: Teaching and Learning in Medicine
https://read.qxmd.com/read/38685593/assessing-the-influence-of-micelle-silymarin-on-laying-hens-performance-egg-quality-water-loss-and-blood-profile
#8
JOURNAL ARTICLE
Golam S Ahammad, Yong H Jeon, In H Kim
Micelle silymarin (MS) is known for its various beneficial properties, including antiswelling, antioxidant, hepatoprotective and antidiabetic effects. The primary goal of this research was to investigate how MS impacts the performance, egg quality, water loss and blood profile of laying hens. 288 Hy-Line brown laying hens, 28 weeks in age, were utilized for this experiment. The hens were randomly allocated into three dietary treatment groups, with each group comprising eight replicates of 12 hens, each housed in individual pens with access to feed and water...
April 29, 2024: Journal of Animal Physiology and Animal Nutrition
https://read.qxmd.com/read/38685167/screening-of-the-effective-sites-of-cichorium-glandulosum-against-hyperuricemia-combined-with-hyperlipidemia-and-its-network-pharmacology-analysis
#9
JOURNAL ARTICLE
Zhiguo Yang, Bo Lyu, Bin Ma, Yuefeng Gao, Dongmei Qin
Cichorium glandulosum, a common traditional Chinese medicine used by Uyghur and Mongolian ethnic groups, is recognized for its potential to ameliorate metabolic disorders. However, the specific efficacy and mechanisms of Cichorium glandulosum in treating the comorbidity of hyperuricaemia and hyperlipidaemia remain unexplored. This study aims to explore the pharmacological effects and mechanisms of Cichorium glandulosum on this comorbidity through a combination of animal experiments, network pharmacology, and molecular docking techniques...
April 26, 2024: Computational Biology and Chemistry
https://read.qxmd.com/read/38683505/dietary-supplementation-with-integral-chia-and-flax-flours-ameliorates-systemic-inflammation
#10
JOURNAL ARTICLE
Narella A Colussi, Juan S Todaro, Juan P Rodríguez, Gabriela B Olea, Leandro A Ferrini, Tania R Stoyanoff, María V Aguirre
INTRODUCTION: Chia and flax seeds are rich in alphalinolenic acid (ALA), which is bioconverted into the active derivatives eicosapentaenoic (EPA) and docosahexaenoic (DHA) having multiple beneficial effects. However, there is limited knowledge about the antiinflammatory effects of chia and flax integral flours diets rich in ALA. OBJECTIVE: The study aimed to evaluate the antiinflammatory effect of dietary supplementation with integral chia and flax flours in a murine model of LPSinduced systemic inflammation...
2024: Medicina
https://read.qxmd.com/read/38682838/the-interplay-of-psychosis-and-non-compliance-with-fatal-outcome-in-an-adult-with-msud
#11
Nadia Falah, Surekha Pendyal, Cina Sasannejad, Allison Gibson, Yu Lin Lee, Marie McDonald, Dwight Koeberl
Significant progress has been achieved in enhancing early outcomes for individuals with maple syrup urine disease (MSUD), a rare metabolic disorder that leads to the accumulation of branched-chain amino acids leucine, isoleucine, and valine, where leucine is known as the primary neurotoxic metabolite. Newborn screening is helpful in early diagnosis and implementation of dietary treatment, thus reducing neurological deterioration and complications in young children. However, patients face the life-long challenge of maintaining metabolic control through adherence to a strict low-leucine diet to avoid long-term consequences of chronic hyperleucinemia, which include cognitive deficits, mood disorders, and movement disorders...
April 29, 2024: American Journal of Medical Genetics. Part A
https://read.qxmd.com/read/38682279/the-relationship-between-the-world-index-for-sustainability-and-health-wish-score-and-mental-health-in-women-a-cross-sectional-study
#12
JOURNAL ARTICLE
Alireza Jafari, Keyhan Lotfi, Hadis Mozaffari, Behzad Zamani, Manije Darooghegi Mofrad, Ali Sheikhi, Pamela J Surkan, Leila Azadbakht
Diet quality has been associated with mental health, and recently, there has been growing interest in the association between sustainability of diets and human health. The objective of this cross-sectional study was to explore the relationship between a newly developed dietary index for health and sustainability, and psychological disorders among Iranian women. Participants in this cross-sectional study included 479 women living in Tehran with no history of chronic disease. A validated 168-item food frequency questionnaire was used to assess dietary intake...
April 29, 2024: British Journal of Nutrition
https://read.qxmd.com/read/38681450/evaluating-the-impact-of-the-covid-19-pandemic-on-first-year-medical-student-nutrition
#13
JOURNAL ARTICLE
Chase Yuan, Priya Nair, Christine Jacob, Natalia Lowry
BACKGROUND: Medical school students in high-stress environments have been shown to make poor personal health decisions ranging from less healthy selections of food to lower rates of exercise. With the emergence of the COVID-19 pandemic adding a major social and health challenge, it is important to examine the effect this new stressor has on the health habits of medical school students. METHODS: All first-year students at Albany Medical College completed a self-recorded three-day log of food intake and exercise modality and duration...
March 2024: Curēus
https://read.qxmd.com/read/38681278/prevalence-of-overweight-obesity-associated-with-anemia-among-female-medical-students-at-umm-al-qura-university-in-makkah-saudi-arabia-a-cross-sectional-study
#14
JOURNAL ARTICLE
Munerah Hamed, Amal Zaghloul, Saeed H Halawani, Bushra A Fatani, Bashair Alshareef, Aisha Almalki, Esraa Alsharif, Qamar A ALhothaly, Salma Alhadhrami, Hanan M Abd Elmoneim
Introduction The obesity epidemic has been linked to a wide range of health and nutritional problems, including anemia, which is often caused by impaired iron metabolism. The World Health Organization considers anemia and obesity to be global health issues among adolescent girls and women experiencing menstruation. This study aims to examine the association between iron deficiency anemia and obesity/overweight among female medical students. Methodology This cross-sectional descriptive study conducted as an online self-administered questionnaire...
March 2024: Curēus
https://read.qxmd.com/read/38681075/a-capricious-case-of-staphylococcus-caprae-thoracic-osteomyelitis
#15
Zoheb Irshad Sulaiman, Patrick J Tu, Stephanie L Baer, Peter J Skidmore
Staphylococcus caprae ( S. caprae ) is a gram positive, coagulase-negative Staphylococci (CoNS) that occurs as a commensal pathogen on the human skin. It recently has been recognized in causing nosocomial infections involving the bloodstream, urinary tract, heart, bone, and joints, particularly in immunosuppressed patients or individuals with prosthetic devices. Previously, S. caprae was underreported as it was difficult to identify in the clinical microbiology laboratory; however, due to advances in molecular identification methods and matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS), more clinical cases are being identified in human isolates and appropriately treated...
2024: IDCases
https://read.qxmd.com/read/38681013/longitudinal-assessment-of-health-related-quality-of-life-in-three-different-hyperphosphatemia-management-groups-of-stage-iii-and-iv-chronic-kidney-disease-patients
#16
JOURNAL ARTICLE
Navjot Kaur, Himansu S Mahapatra, Lalit Pursnani, Muthukumar B, Mansi Singh, Yadunandan P Gupta
INTRODUCTION: Health-related quality of life (HRQoL) has emerged as an important outcome measure inpatients with CKD. The lack of prospective studies on HRQoL and its relation with hyperphosphatemia control measures among pre-dialysis patients necessitated the need for this study. METHODS: This is a prospective, randomized, controlled, open-labelled studythat was conducted for one year on 120 CKD stages III and IV patients divided equally into three groups: Group 1, in which patients under went dietary phosphorus modification; Group 2, in which they were administered calcium-based phosphate binders; and Group 3, in which they were administered non-calcium-based phosphate binders...
2024: Indian Journal of Nephrology
https://read.qxmd.com/read/38680928/association-between-mild-depressive-states-in-polycystic-ovary-syndrome-and-an-unhealthy-lifestyle
#17
JOURNAL ARTICLE
Lingling Li, Zhiyuan Kang, Ping Chen, Baihan Niu, Yaohui Wang, Liping Yang
OBJECTIVE: Polycystic Ovary Syndrome (PCOS) is a prevalent and frequently encountered gynecological disorder. Its high variability and the complexities associated with its management often lead to psychological stress in affected women, manifesting in symptoms of depression. Embracing a healthy lifestyle is fundamental in PCOS treatment. Consistent adherence to a healthy lifestyle not only aids in improving PCOS symptoms but also plays a role in enhancing mental well-being. However, there is currently limited research examining the extent of depression, its prevalence, and its correlation with lifestyle among individuals with PCOS...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38678968/associations-between-diet-and-disease-progression-and-symptomatology-in-multiple-sclerosis-a-systematic-review-of-observational-studies
#18
REVIEW
Eduard Martinez Solsona, Thanasis Tektonidis, Jeanette C Reece, Steve Simpson-Yap, Lucinda J Black, Esmaeil Yousefi Rad, Shelly Coe
BACKGROUND: Although many people with MS (pwMS) modify their diet after diagnosis, there is still no consensus on dietary recommendations for pwMS. A number of observational studies have explored associations of diet and MS progression, but no studies have systematically reviewed the evidence. This systematic review aimed to provide an objective synthesis of the evidence for associations between diet and MS progression, including symptoms and clinical outcomes from observational studies...
April 16, 2024: Multiple Sclerosis and related Disorders
https://read.qxmd.com/read/38678179/does-health-literacy-mediate-the-relationship-between-socioeconomic-status-and-health-related-outcomes-in-the-belgian-adult-population
#19
JOURNAL ARTICLE
Finaba Berete, Lydia Gisle, Stefaan Demarest, Rana Charafeddine, Olivier Bruyère, Stephan Van den Broucke, Johan Van der Heyden
BACKGROUND: Health literacy (HL) has been put forward as a potential mediator through which socioeconomic status (SES) affects health. This study explores whether HL mediates the relation between SES and a selection of health or health-related outcomes. METHODS: Data from the participants of the Belgian health interview survey 2018 aged 18 years or older were individually linked with data from the Belgian compulsory health insurance (n = 8080). HL was assessed with the HLS-EU-Q6...
April 27, 2024: BMC Public Health
https://read.qxmd.com/read/38677612/environmental-concentrations-of-microplastic-induced-gut-microbiota-and-metabolite-disruption-in-silkworm-bombyx-mori
#20
JOURNAL ARTICLE
Xing Zhang, Wenwen Zheng, Wenjing Shao, Wenbin Yu, Yu Yang, Fenju Qin, Wenlin Zhou, Chengliang Gong, Xiaolong Hu
Microplastics (MPs) existing extensively in various ecosystems can be ingested by marine organisms and enter the food chain, resulting the health risks from the presence of MPs in aquatic and terrestrial ecosystems. In the present study, an ideal model for Lepidoptera, the silkworm, Bombyx mori, was exposed to environmental concentrations (0.125 μg, 0.25 μg or 0.5 μg/diet) of MPs for 5 days, and the global changes in gut microbes and metabolites were subsequently examined via 16S rDNA sequencing and GC‒MS-based metabolomics...
April 25, 2024: Chemosphere
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