keyword
https://read.qxmd.com/read/38693311/global-hyperperfusion-after-successful-endovascular-thrombectomy-is-linked-to-worse-outcome-in-acute-ischemic-stroke
#21
JOURNAL ARTICLE
Wookjin Yang, Jeong-Min Kim, Chul-Ho Sohn, Matthew Chung, Youngjoon Kim, Jiyeon Ha, Dong-Wan Kang, Eung-Joon Lee, Han-Yeong Jeong, Keun-Hwa Jung, Seung-Hoon Lee
Patients with stroke may develop hyperperfusion after a successful endovascular thrombectomy (EVT). However, the relationship between post-EVT hyperperfusion and clinical outcomes remains unclear and requires further clarification. We reviewed consecutive patients with anterior circulation occlusion who were successfully recanalized with EVT. Based on post-EVT arterial spin-labeling images, hyperperfusion was categorized as follows: global hyperperfusion (GHP), increased cerebral blood flow (CBF) in ≥ 50% of the culprit vessel territory; focal hyperperfusion (FHP), increased CBF in < 50% of the culprit vessel territory; no hyperperfusion (NHP), no discernible CBF increase...
May 1, 2024: Scientific Reports
https://read.qxmd.com/read/38693189/a-behavioral-advantage-for-the-face-pareidolia-illusion-in-peripheral-vision
#22
JOURNAL ARTICLE
Blake W Saurels, Natalie Peluso, Jessica Taubert
Investigation of visual illusions helps us understand how we process visual information. For example, face pareidolia, the misperception of illusory faces in objects, could be used to understand how we process real faces. However, it remains unclear whether this illusion emerges from errors in face detection or from slower, cognitive processes. Here, our logic is straightforward; if examples of face pareidolia activate the mechanisms that rapidly detect faces in visual environments, then participants will look at objects more quickly when the objects also contain illusory faces...
May 2, 2024: Scientific Reports
https://read.qxmd.com/read/38693159/performance-of-iri-2016-model-in-predicting-total-electron-content-tec-compared-with-gps-tec-over-east-africa-during-2019-2021
#23
JOURNAL ARTICLE
Emmanuel D Sulungu
This study evaluated the applicability of IRI-2016 model in predicting GPS TEC using the monthly means of the five (5) quiet days for equinoxes and solstices months. GPS-derived TEC data were obtained from the IGS network of ground based dual frequency GPS receivers from three stations [(KYN3 0.53° S, 38.53° E; Geom. Lat. 3.91.63° S), (MBAR 0.60° S, 30.74° E; Geom. Lat. 2.76° S) and HOID 1.45° S, 31.34° E; Geom. Lat. 3.71° S]. All the three options for topside Ne of IRI-2016 model and ABT-2009 for bottomside thickness have been used to compute the IRI TEC...
May 1, 2024: Scientific Reports
https://read.qxmd.com/read/38692734/mutation-of-the-als-ftd-associated-rna-binding-protein-fus-affects-axonal-development
#24
JOURNAL ARTICLE
Francesca W van Tartwijk, Lucia C S Wunderlich, Ioanna Mela, Stanislaw Makarchuk, Maximilian A H Jakobs, Seema Qamar, Kristian Franze, Gabriele S Kaminski Schierle, Peter H St George-Hyslop, Julie Qiaojin Lin, Christine E Holt, Clemens F Kaminski
Aberrant condensation and localisation of the RNA-binding protein (RBP) fused in sarcoma (FUS) occur in variants of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Changes in RBP function are commonly associated with changes in axonal cytoskeletal organisation and branching in neurodevelopmental disorders. Here, we asked whether branching defects also occur in vivo in a model of FUS-associated disease. We use two reported Xenopus models of ALS/FTD (of either sex), the ALS-associated mutant FUS(P525L) and a mimic of hypomethylated FUS, FUS(16R)...
May 1, 2024: Journal of Neuroscience
https://read.qxmd.com/read/38692706/remote-topography-guided-transepithelial-photorefractive-combined-phototherapeutic-keratectomy-telesurgery
#25
JOURNAL ARTICLE
Giovanni Alessio, Pasquale Puzo, Camilla Di Pardo, Alessandra Sborgia, Francesco D'Oria
PURPOSE: The purpose of this study was to report the first remote telesurgery in a case of epithelial basement membrane disease with recurrent corneal erosions. METHODS: Topography-guided transepithelial photorefractive combined phototherapeutic keratectomy (PRK-PTK) is a surgical option that treats corneal irregularities and prevents the recurrences of erosions while treating the refractive error. RESULTS: We performed for the first time a remote transepithelial topography-guided combined PRK-PTK using the iRes®2 excimer laser platform (iVIS Technologies, Taranto, Italy), with the surgeon sitting in his own room and controlling the excimer laser in remote with 5G connection through the Remote Control Station and the patient in the operating room...
April 30, 2024: Cornea
https://read.qxmd.com/read/38692488/continuous-glucose-monitoring-using-the-dexcom-g6-in-cardiac-surgery-during-the-postoperative-period
#26
JOURNAL ARTICLE
Steven R Insler, Brett Wakefield, Andrea Debs, Kelly Brake, Ikenna Nwosu, Diana Isaacs, James Bena, M Cecilia Lansang
UNLABELLED: Cardiac surgery is associated with hyperglycemia, which in turn is associated with adverse post-surgical outcomes such as wound infections, acute renal failure, and mortality. This pilot study seeks to determine if Dexcom G6Pro continuous glucose monitor (Dexcom G6Pro CGM) is accurate during the postoperative cardiac surgery period when fluid shifts, systemic inflammatory response syndrome (SIRS), and vasoactive medications are frequently encountered, compared to standard glucose monitoring techniques...
April 29, 2024: Endocrine Practice
https://read.qxmd.com/read/38691337/continued-care-and-provision-of-glasses-are-necessary-to-improve-visual-and-academic-outcomes-in-children-experience-from-a-cluster-randomized-controlled-trial-of-school-based-vision-screening
#27
JOURNAL ARTICLE
Mayu Nishimura, Agnes Wong, Daphne Maurer
OBJECTIVE: To assess the effectiveness of a kindergarten vision screening program by randomly assigning schools to receive or not receive vision screening, then following up 1.5 years later. METHODS: Fifty high-needs elementary schools were randomly assigned to participate or not in a vision screening program for children in senior kindergarten (SK; age 5‒6 years). When the children were in Grade 2 (age 6‒7 years), vision screening was conducted at all 50 schools...
April 30, 2024: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://read.qxmd.com/read/38691309/inter-fractional-error-and-intra-fractional-motion-of-prostate-and-dosimetry-comparisons-of-patient-position-registrations-with-versus-without-fiducial-markers-during-treatment-with-carbon-ion-radiotherapy
#28
JOURNAL ARTICLE
Yuma Iwai, Shinichiro Mori, Hitoshi Ishikawa, Nobuyuki Kanematsu, Shinnosuke Matsumoto, Taku Nakaji, Noriyuki Okonogi, Kana Kobayashi, Masaru Wakatsuki, Takashi Uno, Shigeru Yamada
A few reports have discussed the influence of inter-fractional position error and intra-fractional motion on dose distribution, particularly regarding a spread-out Bragg peak. We investigated inter-fractional and intra-fractional prostate position error by monitoring fiducial marker positions. In 2020, data from 15 patients with prostate cancer who received carbon-ion beam radiotherapy (CIRT) with gold markers were investigated. We checked marker positions before and during irradiation to calculate the inter-fractional positioning and intra-fractional movement and evaluated the CIRT dose distribution by adjusting the planning beam isocenter and clinical target volume (CTV) position...
May 1, 2024: Radiological Physics and Technology
https://read.qxmd.com/read/38690520/risk-factors-predicting-need-for-the-pediatric-intensive-care-unit-picu-post-hematopoietic-cell-transplant-picu-utilization-and-outcomes-following-hct-a-single-center-retrospective-analysis
#29
JOURNAL ARTICLE
Amanda K Johnson, Sinziana Cornea, Samuel Goldfarb, Qing Cao, Julia A Heneghan, Ashish O Gupta
Hematopoietic cell transplant (HCT) is a curative treatment for multiple malignant and non-malignant disorders. While morbidity and mortality have decreased significantly over the years, some patients still require management in the pediatric intensive care unit (PICU) during their HCT course for additional respiratory, cardiovascular, and/or renal support. We retrospectively reviewed pediatric patients (0-18 years) who underwent HCT from January 2015-December 2020 at our institution to determine risk factors for PICU care and evaluate PICU utilization and outcomes...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38690308/causes-of-medication-administration-errors-and-barriers-to-reporting-as-perceived-by-nurses-in-saudi-arabia-a-qualitative-study
#30
JOURNAL ARTICLE
Jazi Shaydied Alotaibi
BACKGROUND: Medication administration errors significantly impact patient safety, potentially leading to severe harm or fatality. Reporting such errors through active systems improves medication administration, thereby enhancing patient safety and the quality of care. However, in the context of Saudi Arabia, little is understood about the causes of medication administration errors and the obstacles hindering their reporting. OBJECTIVE: This study aimed to explore nurses' perceptions of the causes of medication administration errors and the barriers to reporting them...
2024: Belitung nursing journal
https://read.qxmd.com/read/38689854/mathematical-modeling-for-estimating-influenza-vaccine-efficacy-a-case-study-of-the-valencian-community-spain
#31
JOURNAL ARTICLE
Carlos Andreu-Vilarroig, Rafael J Villanueva, Gilberto González-Parra
Vaccine efficacy and its quantification is a crucial concept for the proper design of public health vaccination policies. In this work we proposed a mathematical model to estimate the efficacy of the influenza vaccine in a real-word scenario. In particular, our model is a SEIR-type epidemiological model, which distinguishes vaccinated and unvaccinated populations. Mathematically, its dynamics is governed by a nonlinear system of ordinary differential equations, where the non-linearity arises from the effective contacts between susceptible and infected individuals...
September 2024: Infectious Disease Modelling
https://read.qxmd.com/read/38689737/associations-between-synthetic-phenols-phthalates-and-placental-growth-function-a-longitudinal-cohort-with-exposure-assessment-in-early-pregnancy
#32
JOURNAL ARTICLE
Nicolas Jovanovic, Vicente Mustieles, Marc Althuser, Sarah Lyon-Caen, Nadia Alfaidy, Cathrine Thomsen, Amrit Kaur Sakhi, Azemira Sabaredzovic, Sam Bayat, Anne Couturier-Tarrade, Rémy Slama, Claire Philippat
STUDY QUESTION: Is exposure to environmental chemicals associated with modifications of placental morphology and function? SUMMARY ANSWER: Phthalates, a class of ubiquitous chemicals, showed an association with altered placental weight, placental vascular resistance (PVR), and placental efficiency. WHAT IS KNOWN ALREADY: Only a few epidemiological studies have assessed the effects of phenols and phthalates on placental health. Their results were affected by exposure measurement errors linked to the rapid excretion of these compounds and the reliance on a limited number of spot urine samples to assess exposure...
2024: Human Reproduction Open
https://read.qxmd.com/read/38689619/predictive-performance-of-pharmacokinetic-guided-prophylactic-dosing-of-factor-concentrates-in-hemophilia-a-and-b
#33
JOURNAL ARTICLE
Tine M H J Goedhart, Laura H Bukkems, Anne-Fleur Zwagemaker, Michiel Coppens, Karin Fijnvandraat, Saskia E M Schols, Roger E G Schutgens, Jeroen Eikenboom, Floor C J I Heubel-Moenen, Paula F Ypma, Laurens Nieuwenhuizen, Karina Meijer, Frank W G Leebeek, Ron A A Mathôt, Marjon H Cnossen
BACKGROUND: Pharmacokinetic (PK)-guided dosing is used to individualize factor (F)VIII and FIX replacement therapy. OBJECTIVES: This study investigates the reliability and feasibility of PK-guided prophylactic dosing of factor concentrates in hemophilia A and B. METHODS: In this multicenter, prospective cohort study, people of all ages with hemophilia received prophylactic treatment with factor concentrates based on individual PK parameters...
March 2024: Research and Practice in Thrombosis and Haemostasis
https://read.qxmd.com/read/38689062/vision-language-foundation-model-for-echocardiogram-interpretation
#34
JOURNAL ARTICLE
Matthew Christensen, Milos Vukadinovic, Neal Yuan, David Ouyang
The development of robust artificial intelligence models for echocardiography has been limited by the availability of annotated clinical data. Here, to address this challenge and improve the performance of cardiac imaging models, we developed EchoCLIP, a vision-language foundation model for echocardiography, that learns the relationship between cardiac ultrasound images and the interpretations of expert cardiologists across a wide range of patients and indications for imaging. After training on 1,032,975 cardiac ultrasound videos and corresponding expert text, EchoCLIP performs well on a diverse range of benchmarks for cardiac image interpretation, despite not having been explicitly trained for individual interpretation tasks...
April 30, 2024: Nature Medicine
https://read.qxmd.com/read/38688653/artificial-intelligence-and-chatgpt-in-abdominopelvic-surgery-a-systematic-review-of-applications-and-impact
#35
REVIEW
Marta Goglia, Marco Pace, Marco Yusef, Gaetano Gallo, Matteo Pavone, Niccolò Petrucciani, Paolo Aurello
BACKGROUND/AIM: The integration of AI and natural language processing technologies, such as ChatGPT, into surgical practice has shown promising potential in enhancing various aspects of abdominopelvic surgical procedures. This systematic review aims to comprehensively evaluate the current state of research on the applications and impact of artificial intelligence (AI) and ChatGPT in abdominopelvic surgery summarizing existing literature towards providing a comprehensive overview of the diverse applications, effectiveness, challenges, and future directions of these innovative technologies...
2024: In Vivo
https://read.qxmd.com/read/38688546/reliability-and-validity-of-maximal-respiratory-pressures
#36
REVIEW
Bruna M F Silveira, Hugo L A Pereira, Gabriela Chaves, Daniel G C Ho, Verônica F Parreira
BACKGROUND: Maximal respiratory pressure is used to assess the inspiratory and expiratory muscles strength by using maximal inspiratory pressure (PImax ) and maximal expiratory pressure (PEmax ). This study aimed to summarize and evaluate the reliability and validity of maximal respiratory pressure measurements. METHODS: This systematic review followed the Consensus-based Standards for the Selection of Health Measurement Instruments (COSMIN) recommendations and was reported by using the PRISMA checklist...
April 30, 2024: Respiratory Care
https://read.qxmd.com/read/38688463/relationships-among-baseline-concussion-balance-test-and-gaze-stability-test-scores-in-division-i-collegiate-athletes
#37
JOURNAL ARTICLE
Carolina P Quintana, Anne D Olson, Nicholas R Heebner, Matthew C Hoch
CONTEXT: Sports-related concussions are commonly occurring injuries as a result of sports and recreation that may cause alterations in brain functioning. It is important to be able to evaluate the impact of these injuries on function to manage the injury recovery and ensure recovery. Recent literature suggests the use of objective evaluation strategies in a multifaceted approach to evaluate and manage these injuries. It is important to understand the relationships between the assessments and how best to utilize each assessment...
April 30, 2024: Journal of Sport Rehabilitation
https://read.qxmd.com/read/38687710/the-impact-of-restricted-clinical-experiences-during-a-pandemic-on-newly-graduated-nurses-experiences-a-descriptive-study
#38
MULTICENTER STUDY
Kimberly Nelson, Donna Weyant, Kate Anderson Bogue, Jennifer Parrotte, Carrie Jeffery, Elisabeth George, Robin George, Judith Tinelli, Kimberly Boulanger, Kelly Luckenbaugh, Sarah Ziccardi, Jan Zillman, Connie Henry, Amy Beth Davis, Erin Klinge, Delores McCreary
A multihospital study examined the impact of restricted clinical opportunities during COVID-19 on newly graduated nurses' experiences, self-reported competence, and self-reported errors upon entry into a nurse residency program and at 6 months. Newly graduated nurses' experiences (n = 2,005) were described using comparative data from cohorts before and during restricted experiences across 22 hospitals; minimal differences were observed. Nursing professional development specialists can utilize this information when creating and sustaining transition-to-practice programs...
May 2024: Journal for Nurses in Professional Development
https://read.qxmd.com/read/38687616/local-large-language-models-for-privacy-preserving-accelerated-review-of-historic-echocardiogram-reports
#39
JOURNAL ARTICLE
Akhil Vaid, Son Q Duong, Joshua Lampert, Patricia Kovatch, Robert Freeman, Edgar Argulian, Lori Croft, Stamatios Lerakis, Martin Goldman, Rohan Khera, Girish N Nadkarni
OBJECTIVES: The study developed framework that leverages an open-source Large Language Model (LLM) to enable clinicians to ask plain-language questions about a patient's entire echocardiogram report history. This approach is intended to streamline the extraction of clinical insights from multiple echocardiogram reports, particularly in patients with complex cardiac diseases, thereby enhancing both patient care and research efficiency. MATERIALS AND METHODS: Data from over 10 years were collected, comprising echocardiogram reports from patients with more than 10 echocardiograms on file at the Mount Sinai Health System...
April 30, 2024: Journal of the American Medical Informatics Association: JAMIA
https://read.qxmd.com/read/38687585/african-american-english-speakers-pitch-variation-and-rate-adjustments-for-imagined-technological-and-human-addressees
#40
JOURNAL ARTICLE
Michelle Cohn, Zion Mengesha, Michal Lahav, Courtney Heldreth
This paper examines the adaptations African American English speakers make when imagining talking to a voice assistant, compared to a close friend/family member and to a stranger. Results show that speakers slowed their rate and produced less pitch variation in voice-assistant-"directed speech" (DS), relative to human-DS. These adjustments were not mediated by how often participants reported experiencing errors with automatic speech recognition. Overall, this paper addresses a limitation in the types of language varieties explored when examining technology-DS registers and contributes to our understanding of the dynamics of human-computer interaction...
April 1, 2024: JASA express letters
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