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https://www.readbyqxmd.com/read/28927844/reliability-modelling-of-redundant-safety-systems-without-automatic-diagnostics-incorporating-common-cause-failures-and-process-demand
#1
Siamak Alizadeh, Srinivas Sriramula
Redundant safety systems are commonly used in the process industry to respond to hazardous events. In redundant systems composed of identical units, Common Cause Failures (CCFs) can significantly influence system performance with regards to reliability and safety. However, their impact has been overlooked due to the inherent complexity of modelling common cause induced failures. This article develops a reliability model for a redundant safety system using Markov analysis approach. The proposed model incorporates process demands in conjunction with CCF for the first time and evaluates their impacts on the reliability quantification of safety systems without automatic diagnostics...
September 16, 2017: ISA Transactions
https://www.readbyqxmd.com/read/28913991/seasonal-cycle-and-relationship-of-seasonal-rhino-and-influenza-virus-epidemics-with-episodes-of-asthma-exacerbation-in-different-age-groups
#2
Seung Won Lee, Shinhae Lee, Youn Ho Sheen, Eun Kyo Ha, Sun Hee Choi, Min Suk Yang, Sohyun Hwang, Sung Soon Kim, Jang Hoon Choi, Man Yong Han
PURPOSE: Seasonal variations in asthma exacerbation (AE) are associated with respiratory virus outbreaks and the return of children to school after vacation. This study aims to elucidate the period, phase, and amplitude of seasonal cycles of AE in 5 different age groups with regard to rhino- and influenza virus epidemics in Korea. METHODS: The number of daily emergency department (ED) visits for AE in all age groups of Korea and the nationwide weekly incidence of rhino- and influenza virus, were obtained for 2008-2012...
November 2017: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/28899967/circulating-cell-free-dna-for-metastatic-cervical-cancer-detection-genotyping-and-monitoring
#3
Zhigang Kang, Sanja Stevanović, Christian S Hinrichs, Liang Cao
PURPOSE: Circulating cell-free (ccf) human papillomavirus (HPV) DNA may serve as a unique tumor marker for HPV-associated malignancies, including cervical cancer. We developed a method to genotype and quantify circulating HPV DNA in patients with HPV16- or HPV18-positive metastatic cervical cancer for potential disease monitoring and treatment-related decision making. PATIENTS AND METHODS: In this retrospective study, HPV ccfDNA was measured in serum samples from 19 metastatic cervical cancer patients by duplex digital droplet (dd) PCR...
September 12, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28899590/an-investigation-of-co-combustion-municipal-sewage-sludge-with-biomass-in-a-20kw-bfb-combustor-under-air-fired-and-oxygen-enriched-condition
#4
Rajesh Kumar, Ravi Inder Singh
The behavior of municipal sewage sludge (MSS) with biomass (Guar stalks (GS), Mustard Husk (MH), Prosopis Juliflora Wood (PJW)) has been investigated in a 20kW bubbling fluidized bed (BFB) combustor under both air-fired (A-F) and oxygen-enriched (O-E) conditions. The work presented is divided into three parts, first part cover the thermogravimetric analysis (TGA), second part cover the experimental investigation of BFB combustor, and third part covers the ash analysis. TGA was performed with a ratio of 50%MSS/50%biomass (GS, MH, PJW) and results show that 50%MSS/50%GS has highest combustion characteristic factor (CCF)...
September 9, 2017: Waste Management
https://www.readbyqxmd.com/read/28875111/carotid-cavernous-fistula-masquerading-as-delayed-suprachoroidal-hemorrhage-after-trabeculectomy
#5
Mukesh Jain, Md Shahid Alam, Bipasha Mukherjee, Rajiv Raman
Objective: Carotid cavernous fistulae (CCFs) are abnormal communications between the cavernous sinus and the carotid arterial system. Based on the etiology, CCFs can be traumatic, spontaneous and rarely iatrogenic. We report an interesting case of new onset CCF associated with shallow choroidal detachment after trabeculectomy surgery. Method: Observational case report Result: A 69-year-old male patient presented with complain of proptosis, congestion, and gross diminution of vision in the left eye following trabeculectomy elsewhere...
2017: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/28841162/dihydrochalcones-and-diterpenoids-from-pteris-ensiformis-and-their-bioactivities
#6
Yu-Sheng Shi, Yan Zhang, Wen-Zhong Hu, Xiu-Fu Zhang, Xin Fu, Xia Lv
Two new dihydrochalcone enantiomers (+)-1 and (-)-1, along with eight known compounds 3-10, were obtained from Pteris ensiformis. The planar structures were determined on the basis of extensive 1D and 2DNMR and HRESIMS. The resolution of (+)-1 and (-)-1 was achieved by chiral HPLC analysis. The absolute configurations of (+)-1 and (-)-1 were established by the bulkiness rule using Rh₂(O₂CCF₃)₄-induced circular dichroism (ICD) method. Compounds (+)-1, (-)-1, 8, 9 and 10 exhibited the inhibitory assay of NO production in mouse macrophages stimulated by LPS, with IC50 values of 2...
August 25, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28837440/delayed-onset-cranial-nerve-palsies-after-endovascular-coil-embolization-of-direct-carotid-cavernous-fistulas
#7
Alaa Bou Ghannam, Prem S Subramanian
BACKGROUND: Late recurrence of visual symptoms associated with carotid-cavernous fistula (CCF), including diplopia, is uncommon and raises concern for new or recurrent fistula formation. METHODS: We report 2 patients with traumatic CCFs, where cranial nerve paresis resolved after endovascular CCF treatment only to reappear years later. RESULTS: No evidence of recurrent or new fistula formation was found. Both were treated successfully with strabismus surgery...
August 22, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28822095/validation-of-a-calibration-method-using-the-cross-calibration-factor-and-system-planar-sensitivity-in-quantitative-single-photon-emission-computed-tomography-imaging
#8
Norikazu Matsutomo, Saki Matsumoto, Tomoaki Yamamoto, Eisuke Sato
The present study aimed to validate the absolute quantitative accuracy of a calibration method for single-photon emission computed tomography (SPECT) using cross-calibration factor (CCF)- and system sensitivity-based calibration methods. The CCF obtained with different reconstruction parameters was evaluated using a cylindrical phantom (diameter 20 cm, height 20 cm). SPECT images were acquired with a positron emission tomography/computed tomography (CT) phantom. Subsequently, they were reconstructed by using ordered subset expectation maximization with resolution recovery, scatter, and CT-based attenuation correction...
August 18, 2017: Radiological Physics and Technology
https://www.readbyqxmd.com/read/28795225/unintended-activity-in-homologous-muscle-during-intended-unilateral-contractions-increases-with-greater-task-difficulty
#9
Hironori Watanabe, Hiroaki Kanehisa, Yasuhide Yoshitake
PURPOSE: The present study aimed to examine (1) the effect of task difficulty on unintended muscle activation (UIMA) levels in contralateral homologous muscle, (2) the difference between young and old adults in degree of UIMA with respect to task difficulty, and (3) temporal correlations between intended and contralateral unintended muscle activity at low frequency during unilateral intended force-matching tasks. METHODS: Twelve young (21.8 ± 2.4 years) and twelve old (69...
August 9, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28791882/cooperative-co-evolution-with-formula-based-variable-grouping-for-large-scale-global-optimization
#10
Yuping Wang, Haiyan Liu, Fei Wei, Tingting Zong, Xiaodong Li
For a large-scale global optimization (LSGO) problem, divide-and-conquer is usually considered as an effective strategy to decompose the problem into smaller subproblems, each of which can be then solved individually. Among these decomposition methods, variable grouping is shown to be promising in recent years. Existing variable grouping methods usually assume the problem to be black-box (i.e., assuming that an analytical model of the objective function is unknown), and they attempt to learn appropriate variable grouping that would allow for a better decomposition of the problem...
August 9, 2017: Evolutionary Computation
https://www.readbyqxmd.com/read/28773064/a-combined-high-and-low-cycle-fatigue-model-for-life-prediction-of-turbine-blades
#11
Shun-Peng Zhu, Peng Yue, Zheng-Yong Yu, Qingyuan Wang
Combined high and low cycle fatigue (CCF) generally induces the failure of aircraft gas turbine attachments. Based on the aero-engine load spectrum, accurate assessment of fatigue damage due to the interaction of high cycle fatigue (HCF) resulting from high frequency vibrations and low cycle fatigue (LCF) from ground-air-ground engine cycles is of critical importance for ensuring structural integrity of engine components, like turbine blades. In this paper, the influence of combined damage accumulation on the expected CCF life are investigated for turbine blades...
June 26, 2017: Materials
https://www.readbyqxmd.com/read/28725842/understanding-patients-process-to-use-medical-marijuana-a-southern-new-jersey-community-engagement-project
#12
Tara L Crowell
Given the necessity to better understand the process patients need to go through in order to seek treatment via medical marijuana, this study investigates this process to better understand this phenomenon. Specifically, Compassion Care Foundation (CCF) and Stockton University worked together to identify a solution to this problem. Specifically, 240 new patients at CCF were asked to complete a 1-page survey regarding various aspects associated with their experience prior to their use of medicinal marijuana-diagnosis, what prompted them to seek treatment, level of satisfaction with specific stages in the process, total length of time the process took, and patient's level of pain...
September 2016: Journal of patient experience
https://www.readbyqxmd.com/read/28712734/combined-direct-and-indirect-traumatic-carotid-cavernous-fistula-ccf-case-report-and-review-of-the-literature
#13
Isaac Josh Abecassis, Ryan P Morton, Louis J Kim, Basavaraj V Ghodke, Michael R Levitt
BACKGROUND: Within the current Barrow classification system, there are no categorical descriptions or reports in the literature of cavernous carotid fistulas (CCFs) with both a direct component (type A) and separate indirect contribution (type B, C, or D). We report the first definitive case of a combined simultaneous traumatic direct and indirect CCF, and review the literature on the similar existing entity of traumatic indirect CCFs presenting delayed and subsequent to the treatment of traumatic, direct CCFs...
October 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28710960/bioremediation-potential-of-arsenic-by-non-enzymatically-biofabricated-silver-nanoparticles-adhered-to-the-mesoporous-carbonized-fungal-cell-surface-of-aspergillus-foetidus-mtcc8876
#14
Triparna Mukherjee, Shatarupa Chakraborty, Aksar Ali Biswas, Tapan Kumar Das
Our study aiming for the diminution of arsenic concentration in arsenic contaminated aqua environment by using novel adsorbents based on bio-fabricated silver nanoparticles on a fungal cell surface. Bioreduction of silver ion was done in a non-enzymatic manner in presence of the biomass of fungus Aspergillus foetidus MTCC8876. Aspergillus spp. cells were harvested following the bioreduction and made into carbon by carbonization that led to pore formation (pore width of 2.35 nm) on the cell surface. The average size of silver nanoparticles in the sample of SACF (silver nanoparticles adhered to mesoporous carbonized fungal cell) was 35 nm...
July 12, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28664025/traumatic-carotid-cavernous-fistula-with-a-connection-between-the-supraclinoid-internal-carotid-artery-and-cavernous-sinus-via-a-pseudoaneurysm-presenting-with-delayed-life-threatening-epistaxis
#15
Jun Kyeung Ko, Sang Weon Lee, Tae Hong Lee, Chang Hwa Choi
Traumatic carotid cavernous fistula (CCF) presents most commonly as a direct connection between the cavernous segment of internal carotid artery (ICA) and cavernous sinus (CS), and often accompanies basal skull fracture (BSF). The most frequently reported signs and symptoms are proptosis, chemosis, and bruit. Epistaxis is uncommon symptom of CCF. A 63-year-old man with a history of BSF due to blunt head trauma eight months previously was referred to our emergency room for massive epistaxis. Cerebral angiography demonstrated a high-flow CCF with a connection between the supraclinoid portion of left ICA and CS via a pseudoaneurysm, suggesting the life-threatening epistaxis had been caused by high-flow shunting, through the gap created by the BSF...
April 2017: NMC Case Rep J
https://www.readbyqxmd.com/read/28647659/flow-diverters-as-useful-adjunct-to-traditional-endovascular-techniques-in-treatment-of-direct-carotid-cavernous-fistulas
#16
Christopher S Ogilvy, Rouzbeh Motiei-Langroudi, Mohammad Ghorbani, Christoph J Griessenauer, Abdulrahman Y Alturki, Ajith J Thomas
BACKGROUND: Direct carotid-cavernous sinus fistulas (CCFs) are high-flow arteriovenous shunts that are typically the result of a severe head injury. The endovascular treatment of these lesions includes the use of detachable balloons, coils, liquid embolic agents, and covered stents. To minimize the chance of treatment failure and subsequent complications, endoluminal reconstruction using a flow-diverting stent may be added to the treatment construct. METHODS: We present 3 cases and review the existing literature...
September 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28637958/validation-of-cross-calibration-schemes-for-quantitative-bone-spect-ct-using-different-sources-under-various-geometric-conditions
#17
Noriaki Miyaji, Kenta Miwa, Kazuki Motegi, Takuro Umeda, Kei Wagatsuma, Shohei Fukai, Tomohiro Takiguchi, Takashi Terauchi, Mitsuru Koizumi
PURPOSE: Several cross-calibration schemes have been proposed to produce quantitative values in bone SPECT imaging. Differences in the radionuclide sources and geometric conditions can decrease the accuracy of cross-calibration factor (CCF). The present study aimed to validate the effects of calibration schemes using different sources under various geometric conditions. METHODS: Temporal variations as well as variations in acquisition counts and the shapes of (57)Co standard and (99m)Tc point sources and a (99m)Tc disk source were determined...
2017: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/28636421/analysis-of-origins-of-admission-for-solid-tumor-oncology-inpatients-disease-severity-and-outcomes
#18
Christopher E Wee, Lindsey M Goodman, Leticia Varella, Lisa A Rybicki, Alberto J Montero, Bassam N Estfan, Carolyn H Best, James P Stevenson
PURPOSE: Hospital transfers may affect clinical outcomes. Evaluation of admission by source of transfer, time of admission, and provider type may identify opportunities to improve inpatient outcomes. METHODS: We reviewed charts of patients admitted to the solid tumor oncology service between July and December 2014 from the Cleveland Clinic Foundation (CCF) Main Campus emergency department (ED), CCF Regional EDs, outside hospital (OSH) ED, OSH inpatient services, and CCF outpatient clinics...
July 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28634313/-a-case-of-bilateral-traumatic-carotid-cavernous-fistula
#19
Hanae Terashima, Takashi Higa, Koichi Kato, Tadasuke Tominaga, Masanori Nakagawa, Shigeru Kadoyama, Hiroshi Ujiie, Akira Teramoto
Bilateral traumatic carotid-cavernous fistula(CCF)is rare. It is most commonly caused by a direct head or face injury involving the cavernous sinus and develops immediately after trauma. We report a case of bilateral traumatic CCF that occurred as an intracerebral hematoma(ICH)mimicking apoplexy 5 months later. We treated the patient with point occlusion of venous reflux causing an ICH using coil embolization to remove the hematoma. Three days after we performed trans-venous occlusion of the intercavernous connection and right cavernous sinus using coil embolization through the right inferior petrosal vein, it was identified that the left CCF was occluded after first embolization into the left sylvian vein...
June 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28582503/hugin-hi-c-unifying-genomic-interrogator
#20
Joshua S Martin, Zheng Xu, Alex P Reiner, Karen L Mohlke, Patrick Sullivan, Bing Ren, Ming Hu, Yun Li
Motivation: High throughput chromatin conformation capture (3C) technologies, such as Hi-C and ChIA-PET, have the potential to elucidate the functional roles of non-coding variants. However, most of published genome-wide unbiased chromatin organization studies have used cultured cell lines, limiting their generalizability. Results: We developed a web browser, HUGIn, to visualize Hi-C data generated from 21 human primary tissues and cell lines. HUGIn enables assessment of chromatin contacts both constitutive across and specific to tissue(s) and/or cell line(s) at any genomic loci, including GWAS SNPs, eQTLs and cis-regulatory elements, facilitating the understanding of both GWAS and eQTLs results and functional genomics data...
June 5, 2017: Bioinformatics
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