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https://www.readbyqxmd.com/read/28241721/-radiographic-assessment-of-vertebral-artery-injury-in-anterior-cervical-surgery-in-healthy-adults
#1
H L Wang, L Jiang, F Z Lyu, X S Ma, X L Xia, J Y Jiang
Objectives: To study the relationship between the anatomical parameters of transverse foramen and intervertebral discs in the cross-section of the cervical spine in healthy adults, and to evaluate the risk of vertebral artery injury in the anterior cervical spine surgery. Methods: There were 24 healthy adults(12 male, 12 female) underwent neck CT angiography with clear vertebral artery and the adjacent structure imaging from June to December 2014 in Huashan Hospital, Fudan University. The anatomical parameters of vertebral artery V2 segment with lower cervical vertebrae and intervertebral discs were measured by cross-sectional images of C(3-6)...
March 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28241694/-a-association-of-genetic-polymorphisms-of-xrcc1-and-damage-levels-in-workers-exposed-to-coal-tar-pitch
#2
F Zhang, X C Sun, C D Lu, W Zhang, H Shao, Z X Wang
Objective: To study the relationship between XRCC1 gene polymorphism and DNA damage in peripheral blood lymphocytes of workers exposed to coal tar pitch. Methods: 203 coal tar asphalt device operation area workers (exposure group) and 76 logistics management personnel (control group) as the research ob-ject, determination of 1-hydroxypyrene concentrations in the urine as polycyclic aromatic hydrocarbons expo-sure dose, using the alkaline comet assay evaluation a peripheral blood lymphocyte DNA damage degree, using TaqMan MGB real time PCR method to detect XRCC1 gene 3 loci (XRCC1-194, XRCC1-280 and XRCC1-399) single nucleotide polymorphism...
January 20, 2017: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28241679/-association-between-occupational-stress-and-aminotransferase-activity-in-patients-with-metabolic-syndrome
#3
H Zhao, L Song, Y Qiang, H R Liu, F Y Qiu, X Z Li, H Song
Objective: To investigate the association between occupational stress and activity of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in patients with metabolic syndrome. Methods: A case-control study was performed. According to inclusion and exclusion criteria, among the staff members of enterprises and public institutions aged 20~60 years who underwent physical examination in The Affiliated Hospital of Ningxia Medical University and The People's Hospital of Wuzhong from October 2011 to October 2012, 622 patients with metabolic syndrome who did not have a blood relationship with each other were enrolled as case group, and 600 healthy staff members who also did not have a blood relationshipwith each otherwere enrolled as control group...
December 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28241676/-influencing-factors-for-hearing-loss-in-workers-exposed-to-noise-in-a-cement-plant
#4
X M Wang, H Wu, J Jiao, Y H Li, Z R Zhang, W H Zhou, S F Yu
Objective: To investigate the incidence of noise-induced hearing loss (NIHL) and related influencing factors in workers exposed to noise in a cement plant. Methods: In October 2015, cluster sampling was used for questionnaire investigation and health examination of workers exposed to noise in a cement plant in Henan Province, China. The association of demographic features, living habits, cumulative noise exposure (CNE) , hypertension, and hyperlipidemia with NIHL was analyzed. Results: There was mainly medium-or high-frequency noise in the working place of this cement plant...
December 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28241675/-association-between-single-nucleotide-polymorphismsin-human-heat-shock-protein-70-gene-and-susceptibility-to-noise-induced-hearing-loss
#5
Y H Li, G S Chen, J Jiao, W H Zhou, H Wu, G Z Gu, H L Zhang, Y X Zheng, S F Yu
Objective: To investigate the association between the single nucleotide polymorphisms (SNPs) at rs1043618, rs2075800, and rs2763979 in human heat shock protein 70 (HSP70) gene and susceptibility to noise-induced hearing loss (NIHL) . Methods: A case-control study was performed, and 5 934 workers exposed to noise in an iron and steel plant in Henan, China, who underwent physical examination from 2006 to 2015, were enrolled as study subjects. According to the criteria of binaural average high - frequency (3000, 4000, and 6000 Hz) hearing threshold≥40 dB (HL) and monauralaverage speech-frequency (500, 1000, 2000 Hz) hearing threshold≥26 dB (HL) on the basis of binauralhigh frequency loss measured by pure tone audiometry, as well as the exclusion of NIHL, a total of 286 workers were enrolled as hearing loss group; after the adjustment for sex, type of work, age (difference≤5 years) , and working years of noise exposure (difference ≤2 years) , 286 workers were enrolled as control group...
December 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28241674/-association-between-serum-magnesium-ion-level-and-risk-of-noise-induced-hearing-loss
#6
J Jiao, G Z Gu, G S Chen, Y X Zheng, H L Zhang, Q Geng, Y B Cheng, S F Yu
Objective: To investigate the association between serum magnesium ion level and risk of noise-induced hearing loss (NIHL) . Methods: Acohort study was performed for 7 445 workers exposed to noise in the steelmaking and steel rolling workshops of an iron and steel enterprise in Henan Province, China. The follow-up time was from January 1, 2006 to December 31, 2015. The workers with a binaural average high-frequency hearing threshold of ≥40 dB (HL) were enrolled as case group, and those with a binaural average high-frequency hearing threshold of <35 dB (HL) and a binaural average speech frequency of ≤25 dB (HL) were enrolled as control group...
December 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28241506/influencing-factors-of-the-body-mass-index-of-elementary-students-in-southern-taiwan
#7
Li-Na Chou, Min-Li Chen
The body mass index (BMI) of school children in Taiwan is markedly increasing. According to statistical data from the Taiwan Ministry of Education, the prevalence of obesity in school children from the southern part of the country is the highest in Taiwan. Thus, exploring the factors influencing BMI in elementary school children from southern Taiwan is crucial. This study investigated the influencing factors including physical activity levels, sedentary behaviors, dietary habits, and perceived body shape on the BMIs of elementary school children from southern Taiwan...
February 23, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28241504/trends-of-esophageal-cancer-mortality-in-rural-china-from-1989-to-2013-an-age-period-cohort-analysis
#8
Xudong Gao, Zhenkun Wang, Chan Kong, Fen Yang, Ying Wang, Xiaodong Tan
Background: Esophageal cancer is one of the most common cancers in rural China. The aim of this study was to describe the time trends of esophageal cancer mortality in rural China and to better elucidate the causes of these trends. Methods: The mortality data were obtained from the World Health Organization Mortality Database and the China Health Statistical Yearbook Database. The mortality data were analyzed with age-period-cohort (APC) analysis. Results: Our study indicates that the Age-Standardized Mortality Rates (ASMRs) in rural China generally decreased from 1989 to 2003, and thereafter increased until the year 2008 in both sexes...
February 23, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28241485/genes-gender-environment-and-novel-functions-of-estrogen-receptor-beta-in-the-susceptibility-to-neurodevelopmental-disorders
#9
REVIEW
Mukesh Varshney, Ivan Nalvarte
Many neurological disorders affect men and women differently regarding prevalence, progression, and severity. It is clear that many of these disorders may originate from defective signaling during fetal or perinatal brain development, which may affect males and females differently. Such sex-specific differences may originate from chromosomal or sex-hormone specific effects. This short review will focus on the estrogen receptor beta (ERβ) signaling during perinatal brain development and put it in the context of sex-specific differences in neurodevelopmental disorders...
February 23, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28241462/the-relationship-between-maternal-plasma-leptin-and-adiponectin-concentrations-and-newborn-adiposity
#10
Natália P Castro, Verônica V Euclydes, Fernanda A Simões, Lourdes R A Vaz-de-Lima, Cyro A De Brito, Liania A Luzia, Delan Devakumar, Patrícia H C Rondó
Increased maternal blood concentrations of leptin and decreased adiponectin levels, which are common disturbances in obesity, may be involved in offspring adiposity by programming fetal adipose tissue development. The aim of this study was to assess the relationship between maternal leptin and adiponectin concentrations and newborn adiposity. This was a cross-sectional study involving 210 healthy mother-newborn pairs from a public maternity hospital in São Paulo, Brazil. Maternal blood samples were collected after delivery and leptin and adiponectin concentrations were measured by enzyme-linked immunosorbent assay...
February 23, 2017: Nutrients
https://www.readbyqxmd.com/read/28241426/zinc-status-biomarkers-and-cardiometabolic-risk-factors-in-metabolic-syndrome-a-case-control-study
#11
Erika P S Freitas, Aline T O Cunha, Sephora L S Aquino, Lucia F C Pedrosa, Severina C V C Lima, Josivan G Lima, Maria G Almeida, Karine C M Sena-Evangelista
Metabolic syndrome (MS) involves pathophysiological alterations that might compromise zinc status. The aim of this study was to evaluate zinc status biomarkers and their associations with cardiometabolic factors in patients with MS. Our case control study included 88 patients with MS and 37 controls. We performed clinical and anthropometric assessments and obtained lipid, glycemic, and inflammatory profiles. We also evaluated zinc intake, plasma zinc, erythrocyte zinc, and 24-h urinary zinc excretion. The average zinc intake was significantly lower in the MS group (p < 0...
February 22, 2017: Nutrients
https://www.readbyqxmd.com/read/28241425/heat-shock-factor-1-depletion-sensitizes-a172-glioblastoma-cells-to-temozolomide-via-suppression-of-cancer-stem-cell-like-properties
#12
Chang-Nim Im, Hye Hyeon Yun, Jeong-Hwa Lee
Heat shock factor 1 (HSF1), a transcription factor activated by various stressors, regulates proliferation and apoptosis by inducing expression of target genes, such as heat shock proteins and Bcl-2 (B-cell lymphoma 2) interacting cell death suppressor (BIS). HSF1 also directly interacts with BIS, although it is still unclear whether this interaction is critical in the regulation of glioblastoma stem cells (GSCs). In this study, we examined whether small interfering RNA-mediated BIS knockdown decreased protein levels of HSF1 and subsequent nuclear localization under GSC-like sphere (SP)-forming conditions...
February 22, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28241422/androgen-receptor-signaling-in-bladder-cancer
#13
REVIEW
Peng Li, Jinbo Chen, Hiroshi Miyamoto
Emerging preclinical findings have indicated that steroid hormone receptor signaling plays an important role in bladder cancer outgrowth. In particular, androgen-mediated androgen receptor signals have been shown to correlate with the promotion of tumor development and progression, which may clearly explain some sex-specific differences in bladder cancer. This review summarizes and discusses the available data, suggesting the involvement of androgens and/or the androgen receptor pathways in urothelial carcinogenesis as well as tumor growth...
February 22, 2017: Cancers
https://www.readbyqxmd.com/read/28241390/patterns-of-parental-care-in-neotropical-glassfrogs-fieldwork-alters-hypotheses-of-sex-role-evolution
#14
Jesse Delia, Laura Bravo-Valencia, Karen M Warkentin
Many animals provide parental care to offspring. Parental sex-roles vary extensively across taxa, and such patterns are considered well documented. However, information on amphibians is lacking relative to other vertebrate groups. We combine natural history observations with functional and historical analyses to examine the evolution of egg care in glassfrogs (Centrolenidae). Parental care was considered rare and predominately provided by males. Our field observations of 40 species revealed that care occurs throughout the family, and the caregiving sex changes across lineages...
February 27, 2017: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/28241285/difference-in-differences-analysis-of-the-association-between-state-same-sex-marriage-policies-and-adolescent-suicide-attempts
#15
Julia Raifman, Ellen Moscoe, S Bryn Austin, Margaret McConnell
Importance: Suicide is the second leading cause of death among adolescents between the ages of 15 and 24 years. Adolescents who are sexual minorities experience elevated rates of suicide attempts. Objective: To evaluate the association between state same-sex marriage policies and adolescent suicide attempts. Design, Setting, and Participants: This study used state-level Youth Risk Behavior Surveillance System (YRBSS) data from January 1, 1999, to December 31, 2015, which are weighted to be representative of each state that has participation in the survey greater than 60%...
February 20, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28241220/management-of-severe-pancreatic-fistula-after-pancreatoduodenectomy
#16
F Jasmijn Smits, Hjalmar C van Santvoort, Marc G Besselink, Marilot C T Batenburg, Robbert A E Slooff, Djamila Boerma, Olivier R Busch, Peter P L O Coene, Ronald M van Dam, David P J van Dijk, Casper H J van Eijck, Sebastiaan Festen, Erwin van der Harst, Ignace H J T de Hingh, Koert P de Jong, Johanna A M G Tol, Inne H M Borel Rinkes, I Quintus Molenaar
Importance: Postoperative pancreatic fistula is a potentially life-threatening complication after pancreatoduodenectomy. Evidence for best management is lacking. Objective: To evaluate the clinical outcome of patients undergoing catheter drainage compared with relaparotomy as primary treatment for pancreatic fistula after pancreatoduodenectomy. Design, Setting, and Participants: A multicenter, retrospective, propensity-matched cohort study was conducted in 9 centers of the Dutch Pancreatic Cancer Group from January 1, 2005, to September 30, 2013...
February 22, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28241191/a-large-skin-cancer-screening-quality-initiative-description-and-first-year-outcomes
#17
Laura K Ferris, Melissa I Saul, Yan Lin, Fei Ding, Martin A Weinstock, Alan C Geller, Jian-Min Yuan, Erica Neuren, Spandana Maddukuri, Francis X Solano, John M Kirkwood
Importance: The lack of prospective randomized clinical trials demonstrating that full-body skin examination (FBSE) reduces melanoma morbidity or mortality has prompted an "I" rating from the United States Preventive Services Task Force for population-based skin cancer screening. More data on these screening programs are needed. Objectives: To describe a skin cancer screening quality initiative in a large health care system and to determine if the intervention was associated with screening of a demographically higher-risk population than previous screening programs and if melanoma incidence and thickness differed in screened vs unscreened patients...
February 23, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28241176/predictors-of-obstructive-sleep-apnea-severity-in-adolescents
#18
Mark Baker, Brian Scott, Romaine F Johnson, Ron B Mitchell
Importance: Untreated obstructive sleep apnea has severe health consequences, yet little is known about predictors of sleep apnea severity in the adolescent population. Objective: To evaluate clinical and demographic factors associated with obstructive sleep apnea severity in adolescents. Design, Setting, and Participants: A retrospective case series of 224 children (53% male), ages 12 to 17 years who underwent polysomnography from January 1, 2013, to June 4, 2015...
February 23, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28241168/association-of-depression-and-treated-depression-with-epilepsy-and-seizure-outcomes-a-multicohort-analysis
#19
Colin B Josephson, Mark Lowerison, Isabelle Vallerand, Tolulope T Sajobi, Scott Patten, Nathalie Jette, Samuel Wiebe
Importance: A bidirectional relationship exists between epilepsy and depression. However, any putative biological gradient between depression severity and the risk of epilepsy, and the degree to which depression mediates the influence of independent risk factors for epilepsy, has yet to be examined. Objective: To determine the effect of depression on the risk of epilepsy and seizure outcomes. Design, Setting, and Participants: An observational study of a population-based primary care cohort (all patients free of prevalent depression and epilepsy at 18-90 years of age who were active after the Acceptable Mortality Reporting date in The Health Improvement Network database) and a prospectively collected tertiary care cohort (all patients whose data were prospectively collected from the Calgary Comprehensive Epilepsy Programme)...
February 27, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28241151/outcomes-associated-with-resuming-warfarin-treatment-after-hemorrhagic-stroke-or-traumatic-intracranial-hemorrhage-in-patients-with-atrial-fibrillation
#20
Peter Brønnum Nielsen, Torben Bjerregaard Larsen, Flemming Skjøth, Gregory Y H Lip
Importance: The increase in the risk for bleeding associated with antithrombotic therapy causes a dilemma in patients with atrial fibrillation (AF) who sustain an intracranial hemorrhage (ICH). A thrombotic risk is present; however, a risk for serious harm associated with resumption of anticoagulation therapy also exists. Objective: To investigate the prognosis associated with resuming warfarin treatment stratified by the type of ICH (hemorrhagic stroke or traumatic ICH)...
February 20, 2017: JAMA Internal Medicine
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