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regression to the mean

Gerald Sendlhofer, Gudrun Pregartner, Veronika Gombotz, Karina Leitgeb, Peter Tiefenbacher, Lydia Jantscher, Christian Richter, Magdalena Hoffmann, Lars P Kamolz, Gernot Brunner
AIMS AND OBJECTIVES: The aim of this study was to test the method of self- and external assessment as a feedback system to decrease illegibility and incorrectness of handwritten prescriptions and to reduce additional workload for nursing staff. BACKGROUND: Illegibility and incorrectness of handwritten prescriptions occur very often and are the most crucial factors affecting patient safety. DESIGN: Self- versus external assessment using a 15 items checklist...
December 16, 2018: Journal of Clinical Nursing
Jianbo Li, Weihua Fan, Yu Lu, Dongying Xuan, Ziqiang Liu, Shaohong Huang, Jincai Zhang
BACKGROUND: Erosive tooth wear (ETW) has become a crucial oral health problem over the decades in China. OBJECTIVES: To explore the prevalence and risk indicators of ETW among adolescents in Guangzhou, south China. METHODS: A cross-sectional survey of 720 participants was conducted in Guangzhou, using an equal-sized, stratified, multistage random sampling approach. The participants were from two different age groups(12- and 15-year-olds), 360 per group...
December 16, 2018: Journal of Oral Rehabilitation
Hasan Emre Ünal, Üstüner Birben, Ferhat Bolat
The benefits of the forests are well known and are by their existence alone an amenity. Nonetheless, urbanization as one of the most remarkable features of social development has immense effects on forest resources and land use. In this study, it is hypothesized that there are temporal interactions among the rural population dynamics, urbanization, and forest resources. Data set is based on rural population, total population, and forest areas for the period of 1990-2017. Regression analysis (the ordinary least square, OLS) and dummy variable in regression were used by taking the years into consideration...
December 15, 2018: Environmental Monitoring and Assessment
Patrick Kuhlman, Scott Isom, Timothy S Pardee, Cynthia Burns, Bernard Tawfik, Zanetta S Lamar, Bayard L Powell, Heidi D Klepin
PURPOSE: To investigate the impact of hyperglycemia and glycemic variability during intensive acute myeloid leukemia therapy (AML) on outcomes by age. METHODS: Retrospective study of 262 consecutive patients with newly diagnosed AML hospitalized for intensive induction. Hyperglycemia was assessed by mean blood glucose (BG) (mg/dL) during hospitalization and glycemic variability was determined by the standard deviation (SD) of mean BG. Outcomes were complete remission ± incomplete count recovery (CR + CRi), and overall survival (OS)...
December 15, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
(no author information available yet)
OBJECTIVESeizures are the second-most common presenting symptom in patients with lobar arteriovenous malformations (AVMs). However, few studies have assessed the long-term effect of stereotactic radiosurgery (SRS) on seizure control. The authors of this study assess the outcome of SRS for these patients to identify prognostic factors associated with seizure control.METHODSPatients with AVM who presented with a history of seizure and underwent SRS at the authors' institution between 1987 and 2012 were retrospectively assessed...
December 14, 2018: Journal of Neurosurgery
Heewon Kang, Sung-Il Cho
BACKGROUND: The prevalence of cigarette smoking among South Korean adolescents has decreased markedly over the past decade, which may indicate a norm shift between generations of adolescents. The present study aims to identify the effect of banning smoking in public places and increasing cigarette prices on current adolescent smoking, and to determine whether these policies additionally resulted in cohort effects. METHODS: Repeated cross-sectional survey data, nationally representative of South Korean adolescents, were used...
December 15, 2018: Tobacco Control
David Martinez-Gomez, Irene Esteban-Cornejo, Esther Lopez-Garcia, Esther García-Esquinas, Kabir P Sadarangani, Oscar L Veiga, Fernando Rodriguez-Artalejo
OBJECTIVES: We examined the dose-response relationship between physical activity (PA) and incidence of cardiovascular disease (CVD) risk factors in adults in Taiwan. METHODS: This study included 1 98 919 participants, aged 18-97 years, free of CVD, cancer and diabetes at baseline (1997-2013), who were followed until 2016. At baseline, participants were classified into five PA levels: inactive' (0 metabolic equivalent of task (MET)-h/week), 'lower insufficiently active' (0...
December 15, 2018: British Journal of Sports Medicine
José H Marco, Sandra Alonso
An important goal of mental health specialists is to improve the quality of life and the adaptation of people with common mental disorders on sick leave. Meaning in life is a protective factor for people adjusting to distress and negative events. This study explores the buffering role of meaning in life in the relationship between clinical anxiety or negative affect and maladjustment in participants with common mental disorders on sick leave. The sample was 167 participants with Adjustment, Anxiety and, Depressive Disorders; n = 115 were women and n = 52 men...
December 6, 2018: Psychiatry Research
B L Uhlig, K Hagen, M Engstrøm, M Stjern, G B Gravdahl, T Sand
BACKGROUND: The relationship between insomnia and objectively measured obstructive sleep apnea (OSA) severity has not previously been investigated in both genders in the general population. The main aim of this population-based polysomnography (PSG) study was to evaluate the cross-sectional association between severity of OSA and DSM-V insomnia and insomnia severity. METHODS: A random sample of 1200 participants in the third Nord-Trøndelag Health Study (HUNT3) was invited and 213 (18%) aged between 21 and 82 years underwent an ambulatory PSG, a semi-structured interview, and a sleep-specific questionnaire...
November 17, 2018: Sleep Medicine
Aliai Lanci, Carolina Castagnetti, Saverio Ranciati, Chiara Sergio, Jole Mariella
In the mare, foaling is a critical unpredictable event due to a wide range of gestational length and the absence of clear signs of impending parturition. To predict foaling, pH, inversion sodium potassium and increase of calcium concentration in mammary secretions are used. The aim of this study was to find how many days are left until parturition knowing mare's age (A) and parity (P) combined with ultrasonographic measurements of the fetal orbit in Standardbred mares with normal pregnancy. Eighty healthy Standardbred mares with normal pregnancy were hospitalized for attended delivery...
December 10, 2018: Theriogenology
Lynette Mackey, Melanie J White, Zephanie Tyack, Graham Finlayson, Michelle Dalton, Neil A King
A dual-process model of temperament, incorporating the Behavioural Inhibition System (BIS), Behavioural Activation System (BAS) and effortful control (EC), may help to predict hedonic responses to palatable food and trait disinhibition. PURPOSE: This study aimed to determine if the BIS, BAS and EC predicted liking and wanting for high-fat, sweet foods in adults with overweight and obesity, and if collectively, these variables predicted the eating behaviour trait of Disinhibition. METHODS: 168 adults (104 females, mean BMI = 33...
December 13, 2018: Appetite
Nikoo Soltan, Chantal E Kawalilak, David M Cooper, Saija A Kontulainen, James D Johnston
OBJECTIVE: To determine the agreement between cortical porosity derived from high resolution peripheral quantitative computed tomography (HR-pQCT) (via standard threshold, mean density and density inhomogeneity methods) and synchrotron radiation micro-CT (SR-μCT) derived porosity at the distal radius. METHODS: We scanned 10 cadaveric radii (mean donor age: 79, SD 11 years) at the standard distal region using HR-pQCT and SR-μCT at voxel sizes of 82 μm and 17...
December 13, 2018: Bone
Ilse K Luirink, Jim Determeijer, Barbara A Hutten, Albert Wiegman, Eric Bruckert, Claus P Schmitt, Jaap W Groothoff
BACKGROUND: Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder that may cause life-threatening cardiovascular disease (CVD) at childhood. Marginal effectiveness of statins in reducing low-density lipoprotein cholesterol (LDL-C) is the reason why extracorporeal removal of LDL-C by lipoprotein apheresis (LA) is recommended at the earliest possible age. OBJECTIVE: It is, however, unknown to what extent LA effectively reduces the burden of CVD in children with HoFH...
November 3, 2018: Journal of Clinical Lipidology
Andrea Sitlinger, Rebecca A Shelby, Alyssa N Van Denburg, Heidi White, Sarah N Edmond, Paul K Marcom, Hayden B Bosworth, Francis J Keefe, Gretchen G Kimmick
OBJECTIVE: To explore the impact of symptoms on physical function in women on adjuvant endocrine therapy for breast cancer. METHODS: Eligible women were postmenopausal, had hormone receptor positive, stage I-IIIA breast cancer, completed surgery, chemotherapy, radiation, and on adjuvant endocrine therapy. At a routine follow-up visit, women (N = 107) completed standardized symptom measures: Brief Fatigue Inventory, Brief Pain Inventory, Menopause Specific Quality of Life Questionnaire, Functional Assessment of Cancer Therapy Neurotoxicity scales...
December 12, 2018: Journal of Geriatric Oncology
Lorenz Räber, Konstantinos C Koskinas, Kyohei Yamaji, Masanori Taniwaki, Marco Roffi, Lene Holmvang, Hector M Garcia Garcia, Thomas Zanchin, Rafaela Maldonado, Aris Moschovitis, Giovanni Pedrazzini, Serge Zaugg, Jouke Dijkstra, Christian M Matter, Patrick W Serruys, Thomas F Lüscher, Henning Kelbaek, Alexios Karagiannis, Maria D Radu, Stephan Windecker
OBJECTIVES: This study assessed changes in optical coherence tomography (OCT)-defined plaque composition in patients with ST-elevation myocardial infarction (STEMI) receiving high-intensity statin treatment. BACKGROUND: OCT is a high-resolution modality capable of measuring plaque characteristics including fibrous cap thickness (FCT) and macrophage infiltration. There is limited in vivo evidence regarding the effects of statins on OCT-defined coronary atheroma composition and no evidence in the context of STEMI...
December 6, 2018: JACC. Cardiovascular Imaging
Nicola Veronese, Ai Koyanagi, Brendon Stubbs, Cyrus Cooper, Giuseppe Guglielmi, Renè Rizzoli, Leonardo Punzi, Domenico Rogoli, Maria Gabriella Caruso, Ornella Rotolo, Maria Notarnicola, Nasser Al-Daghri, Lee Smith, Jean-Yves Reginster, Stefania Maggi
OBJECTIVES: Mediterranean diet has several beneficial effects on health, but data regarding the association between Mediterranean diet and knee osteoarthritis (OA) are limited mainly to cross-sectional studies. We investigated whether higher Mediterranean diet adherence is prospectively associated with lower risk of radiographic OA (ROA), radiographic symptomatic knee OA (SxOA) and pain worsening in North American people at high risk or having knee OA. METHODS: Adherence to the Mediterranean diet was evaluated using a validated Mediterranean diet score (aMED), categorized in five categories (Q1 to Q5, higher values reflecting higher adherence to Mediterranean diet)...
December 4, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
Varun Harish, Zhe Li, Peter K M Maitz
BACKGROUND: Biobrane™ is a skin substitute used for the definitive management of partial thickness burns. No studies have examined the optimal timing of Biobrane™ application in this setting. The purpose of this study was to determine whether there was a clinically significant difference in applying Biobrane to a superficial and mid dermal partial thickness burn within 12h after burn. METHODS: From August 2016-February 2017, 29 consecutive superficial and mid dermal partial thickness burn injuries were prospectively treated with Biobrane™ within 12h of the injury...
December 12, 2018: Burns: Journal of the International Society for Burn Injuries
Martin F Reiner, Daniel Müller, Sara Gobbato, Odile Stalder, Andreas Limacher, Nicole R Bonetti, Lisa Pasterk, Marie Méan, Nicolas Rodondi, Drahomir Aujesky, Anne Angelillo-Scherrer, Christian M Matter, Thomas F Lüscher, Giovanni G Camici, Arnold von Eckardstein, Jürg H Beer
INTRODUCTION: Gut microbiota-dependent trimethylamine-N-oxide (TMAO) correlates with arterial thrombotic events including myocardial infarction and stroke, and mortality. However, the association of TMAO with recurrent venous thromboembolism (VTE) and mortality remains unknown. METHODS: TMAO plasma levels were assessed by high performance liquid chromatography in 859 patients aged ≥65 years with acute VTE and categorized into low (<2.28 μmol/L), medium (2...
December 6, 2018: Thrombosis Research
Juliana N Scherer, Daiane Silvello, Vanessa L Volpato, Vinícius S Roglio, Letícia Fara, Felipe Ornell, Lisia von Diemen, Felix Paim Kessler, Flavio Pechansky
The incidence of driving under the influence of psychoactive substances (DUI) and its recidivism can be curtailed by the proper identification of specific and predictive characteristics among drug users. In this sense, interpersonal violence (IV), psychiatric comorbidity and impulsivity seem to play an important role in DUI engagement according to previous studies. There are, however, limited data originated from low and middle income countries. In the present study, drug-using Brazilian drivers reporting DUI (n = 75) presented a higher prevalence of bipolar disorders (BD; DUI: 8% vs...
December 12, 2018: Accident; Analysis and Prevention
Peter D Maskell, A Wayne Jones, Anne Savage, Michael Scott-Ham
The Widmark equation is commonly used when blood alcohol calculations are required in forensic and legal medicine, such as in road-traffic cases and alcohol-related deaths. An important biological variable in this connection is the volume of distribution (Vd ) of ethanol, which is commonly referred to as the rho-factor. Although a person's Vd can be determined empirically through controlled drinking experiments, this approach is not very practical in reality. For this reason, a number of anthropometric equations have been developed that utilize sex, age, height and weight to estimate the person's total body water (TBW) and hence Vd of ethanol...
November 13, 2018: Forensic Science International
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