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Thyroid and ultrasound

Rohit Nayak, Viksit Kumar, Jeremy Webb, Adriana Gregory, Mostafa Fatemi, Azra Alizad
Singular value based spatiotemporal clutter filtering (SVD-STF) can significantly improve the sensitivity of blood flow imaging in small vessels without using contrast agents. However, despite effective clutter filtering, large physiological motion in thyroid imaging can impact coherent integration of the Doppler signal and degrade the visualization of the underlying vasculature. In this study, we hypothesize that motion correction of the clutter filtered Doppler ensemble, prior to the power Doppler estimation, can considerably improve the visualization of smalls vessels in suspicious thyroid nodules...
October 17, 2018: Scientific Reports
Hikmat Permana, Guntur Darmawan, Ervita Ritonga, Maya Kusumawati, Miftahurachman Miftahurachman, Nanny Natalia Soetedjo
Adrenocortical carcinoma (ACC) is a rare solid tumor with an incidence of 0.5 to 2 cases per million per year. It affects women more commonly than men with a ratio of 1.5:1. Ectopic ACC are considered to be extremely rare with no exact incidence data yet. We report an interesting case of hepatic ACC in a young woman with clinical signs of virilization.A-21-year old Sundanese woman visited our endocrine clinic with progressive hirsutism over the face, body, and extremities starting 14 years previously. She had irregular, heavy periods when she was 7 years old...
July 2018: Acta Medica Indonesiana
Manolhas Karkada, Andreu F Costa, Syed Ali Imran, Robert D Hart, Martin Bullock, Gabriela Ilie, Murali Rajaraman
OBJECTIVE: The purpose of this study was to determine the completeness of thyroid ultrasound (US) reports, assess for differences in report interpretation by clinicians, and evaluate for implications in patient care. MATERIALS AND METHODS: We retrospectively reviewed thyroid US examinations performed between January and June 2013 in Nova Scotia, Canada. Baseline examinations that identified a nodule were evaluated for 10 reporting elements. Reports that lacked a comment regarding malignancy risk or a recommendation for biopsy were considered unclassified and were graded by three clinical specialists in accordance with the 2015 American Thyroid Association management guidelines...
October 17, 2018: AJR. American Journal of Roentgenology
Megan R Haymart, Mousumi Banerjee, David Reyes-Gastelum, Elaine Caoili, Edward C Norton
Context: Thyroid cancer incidence increased with the greatest change in adults aged ≥ 65. Objective: To determine the relationship between area-level use of imaging and thyroid cancer incidence over time. Design, Setting and Participants: Longitudinal imaging patterns in Medicare patients aged ≥ 65 years residing in Surveillance, Epidemiology, and End Results (SEER) regions were assessed in relationship to differentiated thyroid cancer diagnosis in patients aged ≥ 65 years included in SEER-Medicare...
October 16, 2018: Journal of Clinical Endocrinology and Metabolism
T Rago, V Cantisani, F Ianni, L Chiovato, R Garberoglio, C Durante, A Frasoldati, S Spiezia, R Farina, G Vallone, A Pontecorvi, P Vitti
Thyroid ultrasonography (US) is the gold standard for thyroid imaging and its widespread use is due to an optimal spatial resolution for superficial anatomic structures, a low cost and the lack of health risks. Thyroid US is a pivotal tool for the diagnosis and follow-up of autoimmune thyroid diseases, for assessing nodule size and echostructure and defining the risk of malignancy in thyroid nodules. The main limitation of US is the poor reproducibility, due to the variable experience of the operators and the different performance and settings of the equipments...
October 16, 2018: Journal of Endocrinological Investigation
Ana Creo, Fares Alahdab, Alaa Al Nofal, Kristen Thomas, Amy Kolbe, Siobhan Pittock
INTRODUCTION: Thyroid cancer is the most common pediatric endocrine cancer; accurate diagnosis and prompt management of pediatric thyroid nodules is critical. The McGill Thyroid Nodule Score (MTNS), based upon clinical, ultrasound (US), and cytology criteria has recently been modified and studied in a pilot pediatric group with good results. We aim to describe the diagnostic accuracy of the pediatric modified MTNS (PMTNS) in a large pediatric cohort. METHODS: We utilized an established retrospective cohort between 1996 and 2015 of 99 patients ≤ 21 years old with 131 thyroid nodules...
October 16, 2018: Clinical Endocrinology
Huaqun Zhao, Xueling Liu, Bei Lei, Ping Cheng, Jian Li, Yedong Wu, Zhen Ma, Fang Wei, Hongyue Su
BACKGROUND: The thyroid imaging reporting and data system (TI-RADS), classified and determined the risk of thyroid nodule malignancy with ultrasound scanning. Contrast-enhanced ultrasound (CEUS) is newly developed methods which could measure perfusion features. OBJECTIVE: The aim of the study was to investigate the value of diagnosing thyroid nodules using TI-RADS combined with CEUS and determine whether improvements were made to the diagnostic accuracy. METHODS: The features of conventional ultrasonography (US) and CEUS ion 117 case of thyroid nodules samples, which were confirmed by fine-needle aspiration and/or surgery, were retrospectively analyzed...
October 10, 2018: Journal of Neuromuscular Diseases
Hui-Xiong Xu, Kun Yan, Bo-Ji Liu, Wen-Ying Liu, Li-Na Tang, Qi Zhou, Jin-Yu Wu, En-Sheng Xue, Bin Shen, Qing Tang, Qin Chen, Hong-Yuan Xue, Ying-Jia Li, Jun Guo, Bin Wang, Fang Li, Chun-Yang Yan, Quan-Shui Li, Yan-Qing Wang, Wei Zhang, Chang-Jun Wu, Wen-Hui Yu, Su-Jin Zhou
Ultrasound elastography has been introduced into clinical practice for a decade and arisen continuous increasing attention worldwide. Shear wave elastography (SWE) is a further extension of ultrasound elastography on the basis of strain elastography, providing a two-dimensional distribution map of tissue stiffness and quantitative measurement of the tissue stiffness in Young's modulus (kPa) and/or shear wave speed (m/s). The Society of Ultrasound in Medicine, Chinese Medical Association (CMA) has recently released a series of guidelines for the use of SWE, including the technique and principle of SWE, and use of SWE in liver fibrosis, breast, thyroid, and musculoskeletal system...
October 10, 2018: Journal of Neuromuscular Diseases
Haixia Guan, Danielle Matonis, Gianluca Toraldo, Stephanie L Lee
Objectives: To examine the prevalence of genetic alterations of thyroid-stimulating hormone receptor ( TSHR ) gene and sodium-iodine symporter ( NIS ) in a series of thyroid fine needle biopsy (FNB) specimens with indeterminate cytology, and to assess the correlation of the type of genetic changes with clinical features and follow-up results in the target thyroid nodule. Methods: Between February 2015 and September 2017, 388 consecutive FNBs with indeterminate cytology were evaluated for TSHR mutations and NIS gene overexpression using ThyroSeqV...
2018: Frontiers in Endocrinology
X Q Ji, C H Zhu, H Y Song
Objective: To understand the healthy status of radiation workers on the staff in Nanjing, and to analysis the relationship between abnormal crystalline lens and its influencing factors. Methods: We described physical indicators including blood pressure (BP) 、blood sugar (BG) 、thyroid B ultrasound、crystalline lens、chromosome and so on among 3 349 radiation workers on the staff in the year 2016 from Jan 1 to Dec 31, and the abnormal results of crystalline lens were analyzed statistically. Results: The rate of abnormal BP、BG、WBC、Thyroid B ultrasound、crystalline lens was 19...
August 20, 2018: Chinese Journal of Industrial Hygiene and Occupational Diseases
Ricardo G Pastorello, Camila Destefani, Pedro H Pinto, Caroline H Credidio, Rafael X Reis, Thiago de A Rodrigues, Maryane C de Toledo, Louise De Brot, Felipe de A Costa, Antonio G do Nascimento, Clóvis A L Pinto, Mauro A Saieg
BACKGROUND: The impact of rapid on-site evaluation (ROSE) on thyroid aspirates has been a matter of extensive debate. In the current study, the authors reviewed all thyroid fine-needle aspiration biopsies (FNABs) performed in their service in recent years to evaluate the impact of ROSE on final adequacy and diagnostic rates. METHODS: All ultrasound-guided FNABs of the thyroid performed between July 2015 and July 2017 were included retrospectively. ROSE was performed by experienced cytopathologists, with production of Romanowsky-stained slides for immediate evaluation...
October 14, 2018: Cancer Cytopathology
John S Abele
This review updates a 2008 report on the establishment of a pathologist-directed ultrasound-guided fine needle aspiration (USGFNA) biopsy clinic in a private practice setting. During this time, ultrasound evaluation of the thyroid has evolved from simply sampling a nodule to a reliable cancer risk assessment (CRA). Because of perceived poor reliability in many local radiology thyroid ultrasound reports, first endocrinologists and then pathologists began performing their own ultrasound evaluations, cancer risk assessments, and USGFNAs...
October 14, 2018: Cancer Cytopathology
Veljko Strajina, Benzon M Dy, Travis J McKenzie, Zahraa Al-Hilli, Robert A Lee, Mabel Ryder, David R Farley, Geoffrey B Thompson, Melanie L Lyden
BACKGROUND: There is a paucity of data regarding optimal treatment options and outcomes for recurrent disease after lateral neck dissection in patients with papillary thyroid carcinoma. METHODS: Retrospective review of patients who underwent either percutaneous ethanol injection or surgery for first-time ipsilateral recurrences after ipsilateral lateral neck dissection for papillary thyroid carcinoma was performed. RESULTS: Follow-up data were available for 54 patients with recurrences in 57 lateral necks treated by either percutaneous ethanol injection (n = 32) or surgery (n = 25)...
October 9, 2018: Surgery
Eun Ju Ha, Dong Gyu Na, Won-Jin Moon, Younghen Lee, Nami Choi
PURPOSE: To compare the diagnostic performance of ultrasound (US)-based risk stratification systems for thyroid nodules in the 2015 ATA guidelines with those of the 2016 KTA/KSThR and 2017 ACR guidelines Materials and Methods: From June 2013 to May 2015, a total of 902 consecutive thyroid nodules were enrolled in four institutions and their US features retrospectively reviewed and classified using the categories defined by the three guidelines. We calculated the malignancy risk of each category, as defined by all three risk-stratification systems, and compared the diagnostic performance of the fine-needle aspiration (FNA) indications of the ATA guidelines with those of the KTA/KSThR and ACR guidelines...
October 12, 2018: Thyroid: Official Journal of the American Thyroid Association
Adam Maciejewski, Rafał Czepczyński, Marek Ruchała
Patients affected by differentiated thyroid cancer are treated surgically and by ablative radioiodine therapy. Post-therapy whole body scan allows detecting thyroid remnants or local and distant metastases, although false-positive findings may be observed. We report a case of 75-year-old woman with follicular thyroid cancer, who underwent ablative radioiodine treatment. On post-therapy whole body scan, abnormal uptake in the left upper abdomen was found, although stimulated thyroglobulin level was not suggestive for distant metastases of differentiated thyroid carcinoma...
October 11, 2018: Endokrynologia Polska
Lindsay Brammen, Martin B Niederle, Philipp Riss, Christian Scheuba, Andreas Selberherr, Georgios Karanikas, Gerd Bodner, Oskar Koperek, Bruno Niederle
BACKGROUND: At the time of diagnosis, one-third of medullary thyroid carcinoma (MTC) patients show lymph node (LN) or distant metastasis. A metastasized MTC requires different surgical strategies. OBJECTIVE: This study aimed to determine the value of ultrasound and [18F]fluoro-dihydroxyphenylalanine positron emission tomography with computed tomography (F-DOPA-PET-CT) in localizing MTC, as well as LN and distant metastasis. METHODS: The study included 50 patients (24 males/26 females) with preoperative ultrasound, F-DOPA-PET-CT, and histologically proven MTC...
October 10, 2018: Annals of Surgical Oncology
Krzysztof Kaliszewski, Agnieszka Zubkiewicz-Kucharska, Paweł Kiełb, Jerzy Maksymowicz, Aleksander Krawczyk, Otto Krawiec
BACKGROUND: The incidence of papillary thyroid microcarcinoma (PTMC) is increasing; however, it is not clear whether this reflects an increase in the incidence of incidental or in that of non-incidentally (presurgically) discovered PTMC (IPTMC vs. NIPTMC). We assessed the incidence of IPTMC and NIPTMC over the past 9 years, to discern whether the increase in PTMC incidence is due to improved diagnostics or to a real increase in the incidence. METHODS: We performed a retrospective chart review of 4327 patients who were consecutively admitted to and surgically treated for thyroid pathology at a single institution...
October 10, 2018: World Journal of Surgical Oncology
Taíse Lima de Oliveira Cerqueira, Yanne Rocha Ramos, Giorgia Bruna Strappa, Mariana Souza de Jesus, Jailciele Gonzaga Santos, Camila Sousa, Gildásio Carvalho, Vladimir Fernandes, Ney Boa-Sorte, Tatiana Amorim, Thiago Magalhães Silva, Ana Marice Teixeira Ladeia, Angelina Xavier Acosta, Helton Estrela Ramos
OBJECTIVE: To evaluate the candidate genes PAX-8, NKX2-5, TSH-R and HES-1 in 63 confirmed cases of thyroid dysgenesis. SUBJECTS AND METHODS: Characterization of patients with congenital hypothyroidism into specific subtypes of thyroid dysgenesis with hormone levels (TT4 and TSH), thyroid ultrasound and scintigraphy. DNA was extracted from peripheral blood leukocytes and the genetic analysis was realized by investigating the presence of mutations in the transcription factor genes involved in thyroid development...
August 2018: Archives of Endocrinology and Metabolism
Nathalie Anne de Oliveira E Silva de Morais, Annie Schtscherbyna Almeida de Assis, Carolina Martins Corcino, Débora Ayres Saraiva, Tatiana Martins Benvenuto Louro Berbara, Carolina Donner de Drummond Ventura, Mario Vaisman, Patrícia de Fátima Dos Santos Teixeira
OBJECTIVES: American Thyroid Association (ATA)'s new guidelines recommend use of population-based trimester-specific reference range (RR) for thyrotropin (TSH) in pregnancy. The aim of this study was to determine first trimester TSH RR for a population of pregnant women in Rio de Janeiro State. SUBJECTS AND METHODS: Two hundred and seventy pregnant women without thyroid illness, defined by National Academy of Clinical Biochemistry, and normal iodine status were included in this sectional study...
August 2018: Archives of Endocrinology and Metabolism
Brian H H Lang, Yu-Cho Woo, Keith Wan-Hang Chiu
BACKGROUND: We aimed to describe changes in serum thyroglobulin (Tg) and anti-Tg autoantibody shortly following high-intensity focused ultrasound (HIFU) ablation in patients with positive anti-Tg status by comparing them with patients with negative anti-Tg and to correlate them with 6-month nodule shrinkage and treatment success. METHODS: From 2015 to 2017, patients who underwent HIFU ablation of a benign thyroid nodule were analysed. Serum Tg and anti-Tg were checked on treatment day (baseline) and 4 days after treatment...
October 10, 2018: International Journal of Hyperthermia
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