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Thyroid and ultrasound

Antonio Rahal Junior, Priscila Mina Falsarella, Guilherme Falleiros Mendes, Jairo Tabacow Hidal, Danielle Macellaro Andreoni, José Flávio Ferreira Lúcio, Marcos Roberto Gomes de Queiroz, Rodrigo Gobbo Garcia
OBJECTIVE: To evaluate safety and effectiveness of nodule volume reduction and thyroid function after percutaneous laser ablation treatment in patients with benign nonfunctioning thyroid nodules. METHODS: Prospective single-center study, from January 2011 to October 2012, which evaluated 30 euthyroid and thyroid antibodies negative patients with benign solitary or dominant nodule with indication of treatment due to compressive symptoms and aesthetic disturbances...
November 29, 2018: Einstein
Yilai Chen, Weiwei Zhan, Wei Zhou, Yijie Dong
This research investigates the application of high-frequency ultrasound (US) examination and US-guided fine-needle aspiration (US-FNA) in diagnosing low-volume metastatic lateral lymph nodes (LLNs) from papillary thyroid carcinoma patients. This study reviewed the medical records of 996 LLNs from 858 patients with suspicious thyroid nodules or after thyroidectomy from January 2013 to January 2016. All patients took US-FNA. The US characteristics and the malignancy rate of LLNs classified into group A and group B based on size were analyzed and compared (group A, ≥6 mm; group B, <6 mm)...
December 3, 2018: Ultrasound Quarterly
Lavinia Vija Racaru, Erwan Gabiache, Sebastien Fontaine, Dominique DʼAure, Loic Mourey, Frederic Courbon, Slimane Zerdoud
An 85-year-old man with a 2-year history of prostate cancer, treated with radiotherapy and hormonal therapy, presented increased prostatic-specific antigen levels. F-choline PET/CT showed focal prostatic uptake consistent with known local recurrence, increased uptake of 2 hypodense thyroid nodules and of 2 left cervical lymph nodes, suspected as thyroid cancer. Neck ultrasound confirmed the high risk of malignancy, and a guided biopsy (of a thyroid nodule and cervical lymph node) revealed cellular infiltrates thyroid transcription factor-1 (TTF-1) negative and prostatic-specific antigen positive, confirming intrathyroid and cervical lymph node metastases of prostate cancer...
December 3, 2018: Clinical Nuclear Medicine
Fabienne Delay, Vincent Dochez, Florence Biquard, Marie-Thérèse Cheve, Philippe Gillard, Chloe Arthuis, Norbert Winer
INTRODUCTION: The incidence of fetal goiters is reported to be around 1 per 40 000 births. The risk of complications is first of all obstetric, directly related to goiter size, but it may also affect longer term fetal and child development, depending on whether the goiter is due to hypo- or hyperthyroidism. Management is multidisciplinary, but not yet consensual and not always optimal by either endocrinologists or obstetricians. OBJECTIVES: The principal objective of this retrospective study was to analyze the data that enabled the physicians to assess whether the goiter was hypo- or hyperthyroid and then to analyze the obstetric practices used in the Pays de Loire network to describe in detail the tools used to diagnose and characterize the goiters and the management chosen in these cases...
December 4, 2018: Journal of Maternal-fetal & Neonatal Medicine
Jorge Racedo, Matthew W Urban
Shear wave elastography (SWE) is a noninvasive ultrasound imaging modality used in the assessment of the mechanical properties of tissues such as the liver, kidney, skeletal muscle, thyroid and the breast. Among the methods used to perform SWE is the comb-push ultrasound shear elastography (CUSE) method. This method uses multiple focused ultrasound beams to generate push beams with acoustic radiation force. Applying these push beams generates propagating shear waves. The propagation motion is measured with ultrafast ultrasound imaging...
November 30, 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Karuna Dewan, Merry E Sebelik, John D Boughter, Courtney B Shires
Background: Post-thyroidectomy dysphonia can result from recurrent laryngeal nerve (RLN) injury. Confirmation of postoperative recurrent nerve function has prompted many surgeons to advocate laryngoscopic examination. Indirect and flexible laryngoscopy permit visualization of vocal cord motion, but not all thyroid surgeons are skilled in these techniques. Indirect laryngoscopy has a significant failure rate due to gag reflexes or anatomical obstruction. Flexible fiberoptic laryngoscopy, the current gold standard, allows reliable visualization of the cords, but perioperative examination is not always feasible for lack of equipment or training...
October 2018: Gland Surgery
Maaike P Smit, Najma S Abdullahi, Boudewijn Bakker, Annette P M van den Elzen
BACKGROUND: Haemolytic group A streptococci (GAS) are the most common bacterial cause of infection in the Netherlands. These bacteria can cause many different non-invasive infections, including scarlet fever. CASE DESCRIPTION: A two-year-old girl presented with fever, tachycardia, exanthema and swelling in the neck. On suspicion of scarlet fever with neck phlegmon we treated her with antibiotics and supportive therapy. Blood and throat cultures revealed growth of haemolytic GAS...
November 26, 2018: Nederlands Tijdschrift Voor Geneeskunde
Ling Zhao, Huixian Yan, Ping Pang, Xiaojing Fan, Xiaomeng Jia, Li Zang, Yukun Luo, Fulin Wang, Guoqing Yang, Weijun Gu, Jin Du, Xianling Wang, Zhaohui Lyu, Jingtao Dou, Yiming Mu
BACKGROUND: Thyroid nodules are very common. Ultrasound (US) and fine needle aspiration (FNA) are both integral in cancer screening. This study investigated the concordance between thyroid nodule sizes measured by US and gross pathologic examination and their relationship with malignancy. METHODS: A retrospective design was used to select consecutive patients with proven carcinoma of the thyroid. The number and maximum diameter of nodules, rates and types of malignancy, as well as predictors of malignancy were determined...
November 29, 2018: Diagnostic Cytopathology
X Chen, Q Zhou, F Wang, F Zhang, H Du, Q Zhang, W Wu, X Gong
BACKGROUND AND PURPOSE: Limitations of ultrasound-guided fine-needle aspiration include nondiagnostic, indeterminate cytology and false-negative results. The BRAF V600E mutation is a specific biomarker for papillary thyroid carcinoma. This study aimed to investigate the additional diagnostic role of the BRAF V600E mutation in high-risk thyroid nodules with benign cytology results. MATERIALS AND METHODS: A total of 787 high-risk nodules in 720 patients underwent ultrasound-fine-needle aspiration...
November 29, 2018: AJNR. American Journal of Neuroradiology
J Chen, Y D Tang, Y S Zhou
Objective: To investigate the association between thyroid nodule diameter measured by ultrasound and thyroid papillocarcinoma. Methods: A total of 389 cases undergoing thyroidectomy because of thyroid nodule between January 2016 and June 2017 in Beijing Anzhen Hospital were retrospectively reviewed. Of these patients, 170 cases had thyroid papillocarcinoma, and 219 cases had benign nodule. The nodules were divided into five groups according to their diameters: ≤1.0 cm, 1.1-2.0 cm, 2.1-3.0 cm, 3.1-4.0 cm, >4...
November 27, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
K Zajíčková, D Zogala, J Kubinyi
(18)F-fluorocholine positron emission tomography/computed tomography (FCH) was performed after inconclusive neck ultrasound and (99)Tc-sestaMIBI SPECT (MIBI) scintigraphy in patients with primary hyperparathyroidism (PHPT) to localize abnormal parathyroid glands before surgery. The results were retrospectively evaluated and compared to postoperative histopathological findings. 13 patients with PHPT were enrolled (mean age 64.3 years, preoperative calcium 2.74 mmol/l and parathyroid hormone 114.6 ng/l). FCH localized hyperfunctioning parathyroid glands in 12 patients of 13 (per patient sensitivity 92 % and positive predictive value (PPV) 100 %)...
November 28, 2018: Physiological Research
Johann Otto Pelz, Elena Belau, Christopher Fricke, Joseph Classen, David Weise
Background: Recent histopathological studies revealed degeneration of the dorsal motor nucleus early in the course of Parkinson's disease (PD). Degeneration of the vagus nerve (VN) axons following neurodegeneration of brainstem vagal nuclei should be detectable by high-resolution ultrasound (HRUS) as a thinning of the VNs. Methods: We measured both VNs cross-sectional area (VN-CSA) of 35 patients with PD and 35 age- and sex-matched healthy controls at the level of the thyroid gland using HRUS. Results: On both sides, the VN-CSA was significantly smaller in PD patients than in controls (right: 2...
2018: Frontiers in Neurology
J Q Zhang, L Yan, H Q Chen, Z Z Wu
Objective: To explore the effect of microwave ablation on thyroid nodules cell activity by the reaction of key enzyme of cell activation. Methods: From November 2017 to February 2018, 104 patients with 120 thyroid nodules underwent ultrasound-guided microwave ablation at Super-minimally Invasive Medicals, Shanghai International Medical Center, aged 14-55 years, 42 males and 62 females.Twice core needle biopsy were performed before and after thermal ablation.The specimen were using hematoxylin and eosin (HE) staining and enzyme histochemical staining with include succinate dehydrogenase (SDH) and nicotinamide adeninedinucleotide phosphate diaphorase (NADPH-d), respectively, and observe under microscope...
November 20, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Davide Ippolito, Stefania Galimberti, Davide Leni, Francesco Vacirca, Ahmed Nasr, Nicola Luigi Bragazzi, Sara Spiga, Valentina Schiavone, Angela Ida Pincelli, Mattia Garancini, Biagio Eugenio Leone, Fabio Pagni
OBJECTIVES: The aim of this study was to evaluate the application of shear wave elastography (SWE) in the routine management of thyroid nodules, as a possible additional tool to the standard sonographic triage. METHODS: A total of 248 consecutive patients scheduled for ultrasound-guided thyroid fine-needle aspiration were included in the study. The presence of a pure colloid lesion was an exclusion criterion. Absolute and relative SWE stiffness measurements on color-coded elastograms, expressed in kilopascals and meters per second, were correlated with radiologic and pathologic features...
November 27, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Margaret Cho, Gabriel Acosta-Gonzalez, Tamar C Brandler, Atreyee Basu, Xiao-Jun Wei, Anthony Simms
Papillary thyroid carcinoma (PTC) is generally associated with an excellent long-term outcome. Distant metastasis is rare with only 5-7% of patients developing distant disease. Metastasis of PTC to the pancreas is an exceedingly rare occurrence. To date, few cases have been reported. We present the case of an 81-year-old man with past medical history of PTC status post total thyroidectomy with local recurrence treated with radioactive iodine and selective neck dissection. Ten years after his initial diagnosis, PET-CT scan revealed a new hypermetabolic 1...
November 27, 2018: Diagnostic Cytopathology
Rui-Na Zhao, Bo Zhang, Yu-Xin Jiang, Xiao Yang, Xing-Jian Lai, Shen-Ling Zhu, Xiao-Yan Zhang
The aim of this study was to identify independent risk factors for thyroid cancer, establish an ultrasonographic multimodality diagnostic model for thyroid nodules, and explore the diagnostic value of the model. From November 2011 to February 2015, 307 patients with a total of 367 thyroid nodules underwent conventional ultrasound, contrast-enhanced ultrasound (CEUS), and ultrasound elastography examinations before surgery. A binary logistic regression analysis was performed to identify independent risk factors for thyroid cancer and to establish a multimodality diagnostic model for thyroid nodules...
November 26, 2018: Ultrasonic Imaging
Ting Xu, Ya Wu, Run-Xin Wu, Yu-Zhi Zhang, Jing-Yu Gu, Xin-Hua Ye, Wei Tang, Shu-Hang Xu, Chao Liu, Xiao-Hong Wu
PURPOSE: To validate and compare diagnostic value of three newly-released Thyroid Imaging Reporting and Data Systems (TIRADS) for cancer risk determination. METHODS: Total 2031 patients with 2465 thyroid nodules were recruited for this study. Ultrasound (US) images were categorized based on three TIRADS editions established by Korean Society of Thyroid Radiology (KSThR), European Thyroid Association (ETA) and American College of Radiology (ACR). ROC curves were established to compare diagnostic value...
November 24, 2018: Endocrine
Danielle Neuman, Russ Kuker, Francesco Vendrame
The coexistence of thyroid functioning nodules and Graves' disease is called Marine-Lenhart syndrome. This condition is estimated to occur in 0.8-2.7% of patients with Graves' disease with few cases reported in the literature. Criteria for the diagnosis are not well defined. Here, we present a case of hyperthyroidism characterized by the presence of stimulating TSH receptor antibodies and severe bilateral exophthalmos. A thyroid uptake and scan revealed an elevated 24-hour iodine-131 uptake and a discrete hot nodule in the upper pole of the right lobe which was also observed with a thyroid ultrasound...
2018: Case Reports in Endocrinology
Zeyad T Sahli, Ashwyn K Sharma, Joseph K Canner, Farah Karipineni, Osama Ali, Satomi Kawamoto, Jen-Fan Hang, Aarti Mathur, Syed Z Ali, Martha A Zeiger, Sheila Sheth
OBJECTIVES: A high proportion of cytologically indeterminate, Afirma Gene Expression Classifier "suspicious" thyroid nodules are benign. The Thyroid Imaging Reporting and Data System (TIRADS), was proposed by the American College of Radiology in 2017 to help classify thyroid nodules based on ultrasound characteristics in a standardized fashion to guide management. We aim to determine the interobserver variability of TIRADS classification among cytologically indeterminate and Afirma suspicious nodules...
November 22, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Hélène Bohec, Ingrid Breuskin, Julien Hadoux, Martin Schlumberger, Sophie Leboulleux, Dana M Hartl
OBJECTIVE: Therapeutic lateral neck dissection (ND) is recommended for N1b papillary thyroid carcinoma (PTC), while prophylactic contralateral lateral ND is not. Given the paucity of data, we investigated the frequency of and risk factors for occult lymph node metastases (LNM) in the contralateral lateral neck for N1b patients. PATIENTS AND METHODS: This is a retrospective study conducted at a cancer center. Inclusion criteria were: unilateral PTC and ipsilateral lateral LNM confirmed by fine-needle aspiration biopsy...
November 21, 2018: World Journal of Surgery
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