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Romain Perolat, Adrian Kastler, Benjamin Nicot, Jean-Michel Pellat, Florence Tahon, Arnaud Attye, Olivier Heck, Kamel Boubagra, Sylvie Grand, Alexandre Krainik
Low back pain (LBP) is the most common pain syndrome, and is an enormous burden and cost generator for society. Lumbar facet joints (FJ) constitute a common source of pain, accounting for 15-45% of LBP. Facet joint degenerative osteoarthritis is the most frequent form of facet joint pain. History and physical examination may suggest but not confirm facet joint syndrome. Although imaging (radiographs, MRI, CT, SPECT) for back pain syndrome is very commonly performed, there are no effective correlations between clinical symptoms and degenerative spinal changes...
August 8, 2018: Insights Into Imaging
Suman K Chowdhury, Ryan M Byrne, Yu Zhou, Xudong Zhang
OBJECTIVE: To examine the lumbar facet joint kinematics in vivo during dynamic lifting and the effects of the load lifted. BACKGROUND: Although extensive efforts have been dedicated to investigating the risk factors of low back pain (LBP) associated with load handling in the workplace, the biomechanics of lumbar facet joints during such activities is not well understood. METHOD: Fourteen healthy participants performed a load-lifting task while a dynamic stereo-radiography system captured their lumbar motion continuously...
August 3, 2018: Human Factors
Rui Liu, Huachao Zhao, Xiaoyu Zhao, Zuoliang He, Yujian Lai, Wanyu Shan, Deribachew Bekana, Gang Li, Jing-Fu Liu
Adsorbed atomic H (H* ads ) facilitates indirect pathways play a major role in the electrochemical removal of various priority pollutants. It is crucial to identify the atomic sites responsible for the provision of H* ads . Herein, through a systematic study of the distribution of H* ads on Pd nanocatalysts with different sizes and, more importantly, deliberately controlled relative abundance of surface defects, we uncovered the central role of defects in the provision of H* ads . Specifically, the H* ads generated on Pd in an electrochemical process increased markedly upon introducing defect sites by changing the morphology to ultrathin polycrystalline Pd nanowires (NWs), while dramatically reduced upon decreasing the number of surface defects through an annealing treatment...
August 1, 2018: Environmental Science & Technology
René Mõttus, Jonah Sinick, Antonio Terracciano, Martina Hřebíčková, Christian Kandler, Juko Ando, Erik Lykke Mortensen, Lucía Colodro-Conde, Kerry L Jang
Mõttus and colleagues (2017) reported evidence that the unique variance in specific personality characteristics captured by single descriptive items often displayed trait-like properties of cross-rater agreement, rank-order stability, and heritability. They suggested that the personality hierarchy should be extended below facets to incorporate these specific characteristics, called personality nuances. The present study attempted to replicate these findings, employing data from 6,287 individuals from 6 countries (Australia, Canada, Czech Republic, Denmark, Japan, and United States)...
July 26, 2018: Journal of Personality and Social Psychology
Po-Chou Liliang, Chao-Ming Hung, Kang Lu, Han-Jung Chen
BACKGROUND: A superior hypogastric plexus block is difficult to perform and hampered by bony structures of the iliac crest and transverse process of L5. OBJECTIVE: We report on a fluoroscopically guided posterolateral transdiscal technique for superior hypogastric plexus neurolysis using a single needle. STUDY DESIGN: A technical note describing interventional procedures. SETTING: The neurosurgery department of a cancer hospital...
July 2018: Pain Physician
Jaewon Lee, Sooho Ham, Dayeon Choi, Du-Jeon Jang
ZnS nanostructures of barbell-shaped porous and hollow nanoplates with a controlled amount of S vacancies have been facilely fabricated via the hydrothermal treatment of ZnS(en)0.5 (en = ethylenediamine) nanoplates. The amount of S vacancies as well as the morphologies of ZnS nanostructures have been controlled by adjusting the hydrolysis time; the layered structure of ZnS(en)0.5 nanoplates decomposes to yield discrete ZnS nanoparticles at two end facets of template nanoplates, producing barbell-shaped porous and hollow ZnS nanoplates with abundant S vacancies finally...
August 7, 2018: Nanoscale
Chad M Brummett, J David Clark
No abstract text is available yet for this article.
July 12, 2018: Anesthesiology
Olav Rohof, Chee Kean Chen
Background and aims The evidence for interventional treatment of thoracic facet joint pain remains limited. This is partly due to inconsistency of the path of thoracic medial branches and a lower incidence of thoracic facet pain among spine pain patients. The purpose of this study is to evaluate the efficacy of bipolar radiofrequency (RF) neurotomy of medial branches for treating chronic thoracic facet joint pain. Methods This is a retrospective record review of all patients diagnosed to have thoracic facet pain with diagnostic block and subsequently treated with bipolar RF neurotomy of medial branch between January 2012 and December 2015...
July 12, 2018: Scandinavian Journal of Pain
Alireza Kamali, Maryam Shokrpour, Bijan Yazdi, Atefeh Khalilpour
Pain is a complex and multi-faceted human perception and several factors could dampen the pain. Therefore, we aimed to comparison of addition of neostigmine and tramadol to 1.5 % lidocaine with paracervical block in reduce of post-operative pain in colporrhaphy. This study was a randomized and double-blind clinical trial for 108 patients' as candidate for colporrhaphy. Patients were randomly divided in three groups (Neostigmine, tramadol and control).We recorded pain in 2 and 6 and 12 hours after surgery, duration of analgesia and mean of use narcotic drug in 24 hours after surgery for all patients...
April 24, 2018: European Journal of Translational Myology
Venkatraman Chandra-Mouli, Marina Plesons, Alka Barua, Priyanka Sreenath, Sunil Mehra
BACKGROUND: Although the need for multi-faceted and multi-sectoral approaches to address the multidimensional issue of child marriage is well-acknowledged, there is a dearth of documented experience on the process of implementing and managing such programmes. METHODS: WHO evaluated a district-level, government-led multi-sectoral intervention to address child marriage in Jamui, Bihar and Sawai Madhopur, Rajasthan, implemented by MAMTA Health Institute for Mother and Child (MAMTA)...
June 28, 2018: Reproductive Health
Hania S Zayed, Amr Amin, Samy Alsirafy, Nahla D Elsayed, Soheir Abo Elfadl, Mohamed Nasreldin, Dalia Enaba, Zeinab Nawito
BACKGROUND AND STUDY AIMS: Central nervous system (CNS) involvement in hepatitis C virus (HCV) infection has different facets such as anxiety, depression, cognitive impairment and vasculitis. We were interested in detecting subclinical CNS involvement in chronic HCV infected subjects with and without systemic vasculitis. PATIENTS AND METHODS: Nineteen patients (15 females and 4 males) with chronic HCV infection (mean age 46.5 ± 7 and mean duration since diagnosis of HCV infection 4...
June 2018: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
Johan Hambræus, Hans Westergren
Introduction Patients exposed to whiplash trauma are at risk of developing pain and dysfunction of the neck and shoulder. Although rarely discussed in the literature, some patients also develop autonomic dysfunction. Case presentation A previously healthy 41-year-old woman was involved in a "head-on" car crash. During the following 3 years she developed severe and complex post-traumatic pain syndrome, which consisted of neck pain, lumbar pain, sensory-motor dysfunction, and myoclonic muscular contractions...
October 1, 2012: Scandinavian Journal of Pain
Juan Carlos Gómez Vega, Juan Carlos Acevedo-González
INTRODUCTION: Lumbar pain affects between 60-90% of people. It is a frequent cause of disability in adults. Pain may be generated by different anatomical structures such as the facet joint. However, nowadays pain produced by the facet joint has no clinical diagnosis. Therefore, the purpose of this article is to propose a clinical diagnostic scale for lumbar facet syndrome. MATERIALS AND METHODS: The study was conducted by means of 6 phases as follows, Phase 1, a systematic review of the literature was performed regarding the clinical diagnosis of facet-based lumbar pain based on the PRISMA checklist; Phase 2, a list of signs and symptoms proposed for diagnosis lumbar pain of facet origin was made...
June 14, 2018: Neurocirugía
Sungsin Jo, Sung Eun Wang, Young Lim Lee, Suman Kang, Bitnara Lee, Jinil Han, Il-Hoon Sung, Ye-Soo Park, Sang-Cheol Bae, Tae-Hwan Kim
BACKGROUND: IL-17A has recently emerged as a potential target that regulates the extensive inflammation and abnormal bone formation observed in ankylosing spondylitis (AS). Blocking IL-17A is expected to inhibit bony ankylosis. Here, we investigated the effects of anti IL-17A agents in AS. METHODS: TNFα, IL-17A, and IL-12/23 p40 levels in serum and synovial fluid from patients with ankylosing spondylitis (AS), rheumatoid arthritis (RA), osteoarthritis (OA), or healthy controls (HC) were measured by ELISA...
June 7, 2018: Arthritis Research & Therapy
David S Stolzenberg, Ryan Pheifer, Joshua Armstrong, George Young, Jeffrey Gehret, Jeremy Simon, George C Chang-Chien
BACKGROUND: Neural blockade of the cervical medial branches is a validated procedure in the diagnosis and treatment of cervical zygapophyseal joint pain. Fluoroscopic visualization of the lower cervical medial branch target zones (CMBTZs) in lateral view is sometimes challenging or not possible due to the patient's shoulders obscuring the target. Large shoulders and short necks often exacerbate the problem. Clear visualization is critical to accuracy and safety. OBJECTIVE: We aim to describe a method for optimal fluoroscopic visualization of the lower CMBTZs using a modified swimmer's view...
May 2018: Pain Physician
Tim Hahn, Marc-Eric Halatsch, Christian Wirtz, Stephan Klessinger
BACKGROUND: Among the various causes of vertigo, the so-called cervicogenic vertigo (CV) has been the most controversial. However, perturbations of proprioceptive signals and abnormal activity of the cervical afferents can induce vertigo. Medial branch blocks (MBBs) are a diagnostic tool designed to test whether a patient's neck pain is mediated by one or more of the medial branches of the dorsal rami of the spinal nerve. It is unknown whether MBBs are also suitable for testing symptoms other than pain...
May 2018: Pain Physician
Samuel Milham, Dave Stetzer
The epidemiology of cutaneous malignant melanoma (CMM) has a number of facets that do not fit with sunlight and ultraviolet light as the primary etiologic agents. Indoor workers have higher incidence and mortality rates of CMM than outdoor workers; CMM occurs in body locations never exposed to sunlight; CMM incidence is increasing in spite of use of UV blocking agents and small changes in solar radiation. Installation of two new fluorescent lights in the milking parlor holding area of a Minnesota dairy farm in 2015 caused an immediate drop in milk production...
July 2018: Medical Hypotheses
Shaoyun Cheng, Yanxiang Cui, Lin Fan, Xiaofeng Mu, Yuzhong Hua
Understanding the function and molecular relevance of distinct miRNAs in endothelial cells (ECs) paves avenues for possible therapeutic intervention by targeting epigenetic mechanisms in vascular endothelial dysfunction, one of the major complications of type 2 diabetes mellitus (T2DM). MiR-342-3p, an obesity-associated miRNA, has recently been shown to be significantly upregulated in human angiosarcoma compared to benign hemangioma, indicating its potential involvement as a proangiogenic factor. Herein, we show that endothelial miR-342-3p expression was significantly compromised in T2DM organisms and this inhibition powerfully blocked vasculogenesis in vivo by repressing endothelial proliferation and migration...
June 6, 2018: Biochemical and Biophysical Research Communications
Steven P Cohen, Tina L Doshi, Octav C Constantinescu, Zirong Zhao, Connie Kurihara, Thomas M Larkin, Scott R Griffith, Michael B Jacobs, William J Kroski, Timothy C Dawson, Ian M Fowler, Ronald L White, Aubrey J Verdun, David E Jamison, Mirinda Anderson-White, Stephanie E Shank, Paul F Pasquina
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: With facet interventions under scrutiny, the authors' objectives were to determine the effectiveness of different lumbar facet blocks and their ability to predict radiofrequency ablation outcomes. METHODS: A total of 229 participants were randomized in a 2:2:1 ratio to receive intraarticular facet injections with bupivacaine and steroid, medial branch blocks, or saline. Those with a positive 1-month outcome (a 2-point or more reduction in average pain score) and score higher than 3 (positive satisfaction) on a 5-point satisfaction scale were followed up to 6 months...
September 2018: Anesthesiology
Wei Ren, Shihui Wen, Sherif Abdulkader Tawfik, Qian P Su, Gungun Lin, Lining A Ju, Michael J Ford, Harshad Ghodke, Antoine M van Oijen, Dayong Jin
Despite significant advances toward accurate tuning of the size and shape of colloidal nanoparticles, the precise control of the surface chemistry thereof remains a grand challenge. It is desirable to conjugate functional bio-molecules onto the selected facets of nanoparticles owing to the versatile capabilities rendered by the molecules. We report here facet-selective conjugation of DNA molecules onto upconversion nanoparticles via ligand competition reaction. Different binding strengths of phosphodiester bonds and phosphate groups on DNA and the surfactant molecules allow one to create heterogeneous bio-chemistry surface for upconversion nanoparticles...
May 14, 2018: Chemical Science
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