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Resting state functional MRI

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https://www.readbyqxmd.com/read/29325327/-resting-state-network-evaluation-of-chronic-smokers-by-functional-magnetic-resonance-imaging
#1
Y Zhang, Y L Li, J L Cheng, A K Dong, K Xu, Y L Li
Objective: To explore the neuromechanism of nicotine smoking, we use independent component analysis (ICA) of resting-state functional magnetic resonance imaging (fMRI) to investigate the differences of functional connectivity of resting-state networks (RSN) in chronic smokers. Methods: Forty-five chronic smokers and thirty-four age and gender matched normal nonsmoking controls experienced resting-state fMRI scanning in 3.0T MRI scanner.Differences of the function connection in each RSN between chronic smokers group and nonsmoking controls group were analyzed by SPM software which was based on Matlab platform...
December 19, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29321969/the-two-year-progression-of-structural-and-functional-cerebral-mri-in-amyotrophic-lateral-sclerosis
#2
R A L Menke, M Proudfoot, K Talbot, M R Turner
MRI has emerged as one of several urgently needed candidate disease progression biomarkers for the neurodegenerative disorder amyotrophic lateral sclerosis (ALS), not least due to its unique ability to non-invasively assess structural and functional cerebral pathology. We sought to identify the extent of detectable change in cerebral MRI metrics over a more prolonged period. Analysis of multi-modal MRI data was performed in a cohort of sixteen patients (13 ALS and 3 with primary lateral sclerosis) in whom it was possible to acquire six-monthly images over two years...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/29320526/temporal-and-spectral-characteristics-of-dynamic-functional-connectivity-between-resting-state-networks-reveal-information-beyond-static-connectivity
#3
Sharon Chiang, Emilian R Vankov, Hsiang J Yeh, Michele Guindani, Marina Vannucci, Zulfi Haneef, John M Stern
Estimation of functional connectivity (FC) has become an increasingly powerful tool for investigating healthy and abnormal brain function. Static connectivity, in particular, has played a large part in guiding conclusions from the majority of resting-state functional MRI studies. However, accumulating evidence points to the presence of temporal fluctuations in FC, leading to increasing interest in estimating FC as a dynamic quantity. One central issue that has arisen in this new view of connectivity is the dramatic increase in complexity caused by dynamic functional connectivity (dFC) estimation...
2018: PloS One
https://www.readbyqxmd.com/read/29315361/networks-of-tau-distribution-in-alzheimer-s-disease
#4
Merle C Hoenig, Gérard N Bischof, Joseph Seemiller, Jochen Hammes, Juraj Kukolja, Özgür A Onur, Frank Jessen, Klaus Fliessbach, Bernd Neumaier, Gereon R Fink, Thilo van Eimeren, Alexander Drzezga
A stereotypical anatomical propagation of tau pathology has been described in Alzheimer's disease. According to recent concepts (network degeneration hypothesis), this propagation is thought to be indicative of misfolded tau proteins possibly spreading along functional networks. If true, tau pathology accumulation should correlate in functionally connected brain regions. Therefore, we examined whether independent components could be identified in the distribution pattern of in vivo tau pathology and whether these components correspond with specific functional connectivity networks...
January 5, 2018: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29309532/no-evidence-for-accelerated-ageing-related-brain-pathology-in-treated-hiv-longitudinal-neuroimaging-results-from-the-comorbidity-in-relation-to-aids-cobra-project
#5
James H Cole, Matthan W A Caan, Jonathan Underwood, Davide De Francesco, Rosan A van Zoest, Ferdinand W N M Wit, Henk J M M Mutsaerts, Rob Leech, Gert J Geurtsen, Peter Portegies, Charles B L M Majoie, Maarten F Schim van der Loeff, Caroline A Sabin, Peter Reiss, Alan Winston, David J Sharp
Background: Despite successful antiretroviral therapy people living with HIV (PLWH) experience higher rates of age-related morbidity, including abnormal brain structure, brain function and cognitive impairment. This has raised concerns that PLWH may experience accelerated ageing-related brain pathology. Methods: We performed a multi-centre longitudinal study of 134 virologically-suppressed PLWH (median age = 56.0 years) and 79 demographically-similar HIV-negative controls (median age = 57...
January 4, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29308987/evidence-for-a-functional-hierarchy-of-association-networks
#6
Eun Young Choi, Garrett K Drayna, David Badre
Patient lesion and neuroimaging studies have identified a rostral-to-caudal functional gradient in the lateral frontal cortex (LFC) corresponding to higher-order (complex or abstract) to lower-order (simple or concrete) cognitive control. At the same time, monkey anatomical and human functional connectivity studies show that frontal regions are reciprocally connected with parietal and temporal regions, forming parallel and distributed association networks. Here, we investigated the link between the functional gradient of LFC regions observed during control tasks and the parallel, distributed organization of association networks...
January 8, 2018: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/29289531/epileptic-seizures-are-reduced-by-autonomic-biofeedback-therapy-through-enhancement-of-fronto-limbic-connectivity-a-controlled-trial-and-neuroimaging-study
#7
Yoko Nagai, Julia Aram, Matthias Koepp, Louis Lemieux, Marco Mula, Hugo Critchley, Sanjay Sisodiya, Mara Cercignani
BACKGROUND: Thirty-percent of patients with epilepsy are drug-resistant, and might benefit from effective noninvasive therapeutic interventions. Evidence is accumulating on the efficacy of autonomic biofeedback therapy using galvanic skin response (GSR; an index of sympathetic arousal) in treating epileptic seizures. This study aimed to extend previous controlled clinical trials of autonomic biofeedback therapy with a larger homogeneous sample of patients with temporal lobe epilepsy. In addition, we used neuroimaging to characterize neural mechanisms of change in seizure frequency following the therapy...
December 13, 2017: EBioMedicine
https://www.readbyqxmd.com/read/29285280/altered-network-efficiency-of-functional-brain-networks-in-patients-with-breast-cancer-after-chemotherapy
#8
Han Xuan, Chen Gan, Wen Li, Zhonglian Huang, Longsheng Wang, Qianqian Jia, Zhendong Chen, Huaidong Cheng
Objective: To investigate the topological organization of functional brain networks in chemotherapy-treated breast cancer (BC) patients with source memory impairment. Methods: Twenty-eight patients with BCfollowingchemotherapyand40age-and education-matched healthy controls (HCs) were recruited in the current study. All participants underwent source memory tests and resting-state functional MRI scans. Individual whole-brain functional brain networks were constructed and analyzed using graph-based network approaches...
December 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/29282320/detection-of-synchronous-brain-activity-in-white-matter-tracts-at-rest-and-under-functional-loading
#9
Zhaohua Ding, Yali Huang, Stephen K Bailey, Yurui Gao, Laurie E Cutting, Baxter P Rogers, Allen T Newton, John C Gore
Functional MRI based on blood oxygenation level-dependent (BOLD) contrast is well established as a neuroimaging technique for detecting neural activity in the cortex of the human brain. While detection and characterization of BOLD signals, as well as their electrophysiological and hemodynamic/metabolic origins, have been extensively studied in gray matter (GM), the detection and interpretation of BOLD signals in white matter (WM) remain controversial. We have previously observed that BOLD signals in a resting state reveal structure-specific anisotropic temporal correlations in WM and that external stimuli alter these correlations and permit visualization of task-specific fiber pathways, suggesting variations in WM BOLD signals are related to neural activity...
December 27, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29278773/an-evaluation-of-the-efficacy-reliability-and-sensitivity-of-motion-correction-strategies-for-resting-state-functional-mri
#10
Linden Parkes, Ben Fulcher, Murat Yu Cel, Alex Fornitod
Estimates of functional connectivity derived from resting-state functional magnetic resonance imaging (rs-fMRI) are sensitive to artefacts caused by in-scanner head motion. This susceptibility has motivated the development of numerous denoising methods designed to mitigate motion-related artefacts. Here, we compare popular retrospective rs-fMRI denoising methods, such as regression of head motion parameters and mean white matter (WM) and cerebrospinal fluid (CSF) (with and without expansion terms), aCompCor, volume censoring (e...
December 23, 2017: NeuroImage
https://www.readbyqxmd.com/read/29277650/macroscale-variation-in-resting-state-neuronal-activity-and-connectivity-assessed-by-simultaneous-calcium-imaging-hemodynamic-imaging-and-electrophysiology
#11
Matthew C Murphy, Kevin C Chan, Seong-Gi Kim, Alberto L Vazquez
Functional imaging of spontaneous activity continues to play an important role in the field of connectomics. The most common imaging signal used for these experiments is the blood-oxygen-level-dependent (BOLD) functional MRI (fMRI) signal, but how this signal relates to spontaneous neuronal activity remains incompletely understood. Genetically encoded calcium indicators represent a promising tool to study this problem, as they can provide brain-wide measurements of neuronal activity compared to point measurements afforded by electrophysiological recordings...
December 22, 2017: NeuroImage
https://www.readbyqxmd.com/read/29275589/-characteristics-of-cognitive-impairment-and-the-resting-state-functional-mri-in-patients-with-leukoaraiosis
#12
Q Li, L Q Zhao, F Y Hu
Objective: To investigate the features of cognitive impairment and potential physiopathologic mechanism using neuropsychological assessment and resting state functional magnetic resonance imaging (rs-fMRI) in patients with leukoaraiosis (LA). Methods: A total of 13 patients with LA (LA group) and 13 healthy controls (NC group) from Shanxi Provincial People's Hospital between January and June 2016 were recruited. The two groups were matched for age, sex, education, and vascular risk factors. All the subjects underwent neuropsychological assessment and the scan of rs-fMRI...
December 5, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29275207/grey-matter-and-functional-connectivity-in-anterior-cingulate-cortex-is-associated-with-the-state-of-mental-silence-during-sahaja-yoga-meditation
#13
Sergio Elías Hernández, Alfonso Barros-Loscertales, Yaqiong Xiao, José Luis González-Mora, Katya Rubia
Some meditation techniques teach the practitioner to achieve the state of mental silence. The aim of this study was to investigate brain regions that are associated in their volume and functional connectivity with the depth of mental silence in long-term practitioners of Sahaja Yoga Meditation. Twenty-three long-term practitioners of this meditation were scanned using Magnetic Resonance Imaging. In order to identify the neural correlates of the depth of mental silence, we tested which grey matter volumes were correlated with the depth of mental silence and which regions these areas were functionally connected to under a meditation condition...
December 21, 2017: Neuroscience
https://www.readbyqxmd.com/read/29274501/using-diffusion-mri-to-discriminate-areas-of-cortical-grey-matter
#14
Tharindu Ganepola, Zoltan Nagy, Aurobrata Ghosh, Theodore Papadopoulo, Daniel C Alexander, Martin I Sereno
Cortical area parcellation is a challenging problem that is often approached by combining structural imaging (e.g., quantitative T1, diffusion-based connectivity) with functional imaging (e.g., task activations, topological mapping, resting state correlations). Diffusion MRI (dMRI) has been widely adopted to analyse white matter microstructure, but scarcely used to distinguish grey matter regions because of the reduced anisotropy there. Nevertheless, differences in the texture of the cortical 'fabric' have long been mapped by histologists to distinguish cortical areas...
December 20, 2017: NeuroImage
https://www.readbyqxmd.com/read/29260367/larger-volume-and-different-functional-connectivity-of-the-amygdala-in-women-with-premenstrual-syndrome
#15
Demao Deng, Yong Pang, Gaoxiong Duan, Huimei Liu, Hai Liao, Peng Liu, Yanfei Liu, Shasha Li, Wenfu Chen, Danhong Wen, Chunmei Xuan, Min Li
OBJECTIVES: To assess structural and functional changes of the amygdala due to premenstrual syndrome (PMS) using magnetic resonance imaging (MRI). METHODS: Twenty PMS patients and 21 healthy control (HC) subjects underwent a 6-min resting-state fMRI scan during the luteal phase as well as scanning high-resolution T1-weighted images. Subcortical amygdala-related volume and functional connectivity (FC) were estimated between the two groups. Each subject completed a daily record of severity of problems (DRSP) to measure the severity of clinical symptoms...
December 19, 2017: European Radiology
https://www.readbyqxmd.com/read/29249930/effects-of-field-map-distortion-correction-on-resting-state-functional-connectivity-mri
#16
Hiroki Togo, Jaroslav Rokicki, Kenji Yoshinaga, Tatsuhiro Hisatsune, Hiroshi Matsuda, Nobuhiko Haga, Takashi Hanakawa
Magnetic field inhomogeneities cause geometric distortions of echo planar images used for functional magnetic resonance imaging (fMRI). To reduce this problem, distortion correction (DC) with field map is widely used for both task and resting-state fMRI (rs-fMRI). Although DC with field map has been reported to improve the quality of task fMRI, little is known about its effects on rs-fMRI. Here, we tested the influence of field-map DC on rs-fMRI results using two rs-fMRI datasets derived from 40 healthy subjects: one with DC (DC+) and the other without correction (DC-)...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29249338/wavelet-coherence-based-classifier-a-resting-state-functional-mri-study-on-neurodynamics-in-adolescents-with-high-functioning-autism
#17
Antoine Bernas, Albert P Aldenkamp, Svitlana Zinger
BACKGROUND AND OBJECTIVE: The autism spectrum disorder (ASD) diagnosis requires a long and elaborate procedure. Due to the lack of a biomarker, the procedure is subjective and is restricted to evaluating behavior. Several attempts to use functional MRI as an assisting tool (as classifier) have been reported, but they barely reach an accuracy of 80%, and have not usually been replicated or validated with independent datasets. Those attempts have used functional connectivity and structural measurements...
February 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29240648/reliable-new-measures-capturing-low-frequency-fluctuations-from-resting-state-functional-mri
#18
Jae-Chang Kim, Sunghyon Kyeong
Resting-state functional MRI (rsfMRI) is one of the most important neuroimaging modalities for investigating alterations in the resting-state networks of the human brain, given that abnormal neural activity during the resting state is associated with neurological disorders. However, neuroimaging results obtained from rsfMRI have rarely been replicated with repeated measurements. Therefore, we aimed to develop new measures to extract highly reliable and reproducible functional neuroimaging metrics from rsfMRI data...
December 13, 2017: Neuroreport
https://www.readbyqxmd.com/read/29239977/increased-resting-state-brain-entropy-in-alzheimer-s-disease
#19
Shao-Wei Xue, Yonghu Guo
Entropy analysis of resting-state functional MRI (R-fMRI) is a novel approach to characterize brain temporal dynamics and facilitates the identification of abnormal brain activity caused by several disease conditions. However, Alzheimer's disease (AD)-related brain entropy mapping based on R-fMRI has not been assessed. Here, we measured the sample entropy and voxel-wise connectivity of the network degree centrality (DC) of the intrinsic brain activity acquired by R-fMRI in 26 patients with AD and 26 healthy controls...
December 12, 2017: Neuroreport
https://www.readbyqxmd.com/read/29230170/the-dancing-brain-structural-and-functional-signatures-of-expert-dance-training
#20
Agnieszka Z Burzynska, Karolina Finc, Brittany K Taylor, Anya M Knecht, Arthur F Kramer
Dance - as a ritual, therapy, and leisure activity - has been known for thousands of years. Today, dance is increasingly used as therapy for cognitive and neurological disorders such as dementia and Parkinson's disease. Surprisingly, the effects of dance training on the healthy young brain are not well understood despite the necessity of such information for planning successful clinical interventions. Therefore, this study examined actively performing, expert-level trained college students as a model of long-term exposure to dance training...
2017: Frontiers in Human Neuroscience
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