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Resting state functional MRI

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https://www.readbyqxmd.com/read/29136110/meta-connectomic-analysis-reveals-commonly-disrupted-functional-architectures-in-network-modules-and-connectors-across-brain-disorders
#1
Zhiqiang Sha, Mingrui Xia, Qixiang Lin, Miao Cao, Yanqing Tang, Ke Xu, Haiqing Song, Zhiqun Wang, Fei Wang, Peter T Fox, Alan C Evans, Yong He
Neuropsychiatric disorders are increasingly conceptualized as disconnection syndromes that are associated with abnormal network integrity in the brain. However, whether different neuropsychiatric disorders show commonly dysfunctional connectivity architectures in large-scale brain networks remains largely unknown. Here, we performed a meta-connectomic study to identify disorder-related functional modules and brain regions by combining meta-analyses of 182 published resting-state functional MRI studies in 11 neuropsychiatric disorders and graph-theoretical analyses of 3 independent resting-state functional MRI datasets with healthy and diseased populations (Alzheimer's disease and major depressive disorder [MDD])...
November 9, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/29134288/task-relevant-brain-networks-identified-with-simultaneous-pet-mr-imaging-of-metabolism-and-connectivity
#2
Andreas Hahn, Gregor Gryglewski, Lukas Nics, Lucas Rischka, Sebastian Ganger, Helen Sigurdardottir, Chrysoula Vraka, Leo Silberbauer, Thomas Vanicek, Alexander Kautzky, Wolfgang Wadsak, Markus Mitterhauser, Markus Hartenbach, Marcus Hacker, Siegfried Kasper, Rupert Lanzenberger
Except for task-specific functional MRI, the vast majority of imaging studies assessed human brain function at resting conditions. However, tracking task-specific neuronal activity yields important insight how the brain responds to stimulation. We specifically investigated changes in glucose metabolism, functional connectivity and white matter microstructure during task performance using several recent methodological advancements. Opening the eyes and right finger tapping had elicited an increased glucose metabolism in primary visual and motor cortices, respectively...
November 13, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/29123400/comparison-of-spontaneous-brain-activity-revealed-by-regional-homogeneity-in-aqp4-igg-neuromyelitis-optica-optic-neuritis-versus-mog-igg-optic-neuritis-patients-a-resting-state-functional-mri-study
#3
Junqing Wang, Yuan Tian, Yi Shao, Hui Feng, Limin Qin, Weiwei Xu, Hongjuan Liu, Quangang Xu, Shihui Wei, Lin Ma
Objective: Many previous studies have demonstrated that neuromyelitis optica (NMO) patients have abnormalities of brain anatomy and function. However, differences in spontaneous brain activity between myelin oligodendrocyte glycoprotein (MOG)-IgG ON and aquaporin 4(AQP4)-neuromyelitis optica-optic neuritis (ON) remain unknown. In the current study, we investigated the brain neural homogeneity in MOG-IgG ON versus AQP4-IgG NMO-ON subjects by regional homogeneity (ReHo) method using magnetic resonance imaging (MRI)...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29117709/detecting-perfusion-pattern-based-on-the-background-low-frequency-fluctuation-in-resting-state-functional-mri-data-and-its-influence-on-resting-state-networks-an-iterative-post-processing-approach
#4
Tianyi Qian, Davide Zanchi, Cristelle Rodriguez, Marine Ackermann, Panteleimon Giannakopoulos, Sven Haller
INTRODUCTION: RS-fMRI is based on the assumption that the vascular response and the blood oxygenation level dependent (BOLD) response are homogenous across the entire brain. However, this a priori hypothesis is not consistent with the well-known variability of cerebral vascular territories. In order to explore whether the RS networks are influenced by varied vascular speed in different vascular territories, we assessed the time-shift maps that give an estimate of the local timing of the vascular response and check whether local differences in this timing have an impact on the estimates of RS networks...
November 8, 2017: Brain Connectivity
https://www.readbyqxmd.com/read/29113406/altered-dmn-functional-connectivity-and-regional-homogeneity-in-partial-epilepsy-patients-a-seventy-cases-study
#5
Chong-Yu Hu, Xiaoping Gao, Lili Long, Xiaoyan Long, Chaorong Liu, Yayu Chen, Yuanyuan Xie, Chujuan Liu, Bo Xiao, Zhe-Yu Hu
Purpose: Clinically diagnosed partial epilepsy is hard to be functionally diagnosed by regular electroencephalograph (EEG) and conventional magnetic resonance imaging (MRI). By collecting transient brain regional signals, blood oxygenation level-dependent (BOLD) function MRI (BOLD-fMRI) can provide brain function change information with high accuracy. By using resting state BOLD-fMRI technique, we aim to investigate the changes of brain function in partial epilepsy patients. Methods: BOLD-fMRI scanning was performed in 70 partial epilepsy and 70 healthy people...
October 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/29113386/chemotherapy-induced-changes-of-cerebral-activity-in-resting-state-functional-magnetic-resonance-imaging-and-cerebral-white-matter-in-diffusion-tensor-imaging
#6
Caiqin Mo, Hailong Lin, Fangmeng Fu, Lin Lin, Jie Zhang, Meng Huang, Chuan Wang, Yunjing Xue, Qing Duan, Weiwen Lin, Xiangjin Chen
While chemotherapy related cognitive disorder has been described in many studies, but we still lack relatively reliable and objective diagnostic tools, and there are few similar studies in Asian patients. We recruited Asian breast cancer patients to perform a cohort study to uncover chemotherapy related cognitive disorder by using resting-state functioning magnetic resonance imaging (RS-fMRI) and magnetic resonance diffusion tensor imaging (DTI) combined with neuropsychologic assessments. This is the first prospective study which combines RS-fMRI and DTI to detect chemotherapy related cognitive disorder...
October 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/29105886/altered-structure-and-functional-connection-in-patients-with-classical-trigeminal-neuralgia
#7
Yuan-Hsiung Tsai, Rui Yuan, Dharni Patel, Subhashini Chandrasekaran, Hsu-Huei Weng, Jen-Tsung Yang, Ching-Po Lin, Bharat B Biswal
Classical trigeminal neuralgia (TN) is a specific type of neuropathic orofacial pain of which the plasticity of brain structure and connectivity have remained largely unknown. A total of 62 TN patients were included and referred to MRI scans. Voxel-based morphometry was used to analyze the change of gray matter volume. Resting-state functional imaging was used to analyze the connectivity between brain regions. The results showed gray matter volume reduction in components of the prefrontal cortex, precentral gyrus, cerebellar tonsil, thalamus, hypothalamus, and nucleus accumbens among right TN patient and in the inferior frontal gyrus, precentral gyrus, cerebellum, thalamus, ventral striatum, and putamen among left TN patients...
November 6, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29104740/cerebellum-and-neurodegenerative-diseases-beyond-conventional-magnetic-resonance-imaging
#8
REVIEW
Enricomaria Mormina, Maria Petracca, Giulia Bommarito, Niccolò Piaggio, Sirio Cocozza, Matilde Inglese
The cerebellum plays a key role in movement control and in cognition and cerebellar involvement is described in several neurodegenerative diseases. While conventional magnetic resonance imaging (MRI) is widely used for brain and cerebellar morphologic evaluation, advanced MRI techniques allow the investigation of cerebellar microstructural and functional characteristics. Volumetry, voxel-based morphometry, diffusion MRI based fiber tractography, resting state and task related functional MRI, perfusion, and proton MR spectroscopy are among the most common techniques applied to the study of cerebellum...
October 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/29092081/novel-findings-in-obstetric-brachial-plexus-palsy-a-study-of-corpus-callosum-volumetry-and-resting-state-functional-magnetic-resonance-imaging-of-sensorimotor-network
#9
Kishore Kislay, Bhagavatula Indira Devi, Dhananjaya Ishwar Bhat, Dhaval Prem Shukla, Arun Kumar Gupta, Rajanikant Panda
BACKGROUND: The response of the brain to obstetric brachial plexus palsy (OBPP) is not clearly understood. We propose that even a peripheral insult at the developmental stage may result in changes in the volume of white matter of the brain, which we studied using corpus callosum volumetry and resting-state functional magnetic resonance imaging (rsfMRI) of sensorimotor network. OBJECTIVE: To study the central neural effects in OBPP. METHODS: We performed an MRI study on a cohort of 14 children who had OBPP and 14 healthy controls...
October 28, 2017: Neurosurgery
https://www.readbyqxmd.com/read/29078281/multimodal-mapping-of-the-brain-s-functional-connectivity-and-the-adult-outcome-of-attention-deficit-hyperactivity-disorder
#10
Gustavo Sudre, Eszter Szekely, Wendy Sharp, Steven Kasparek, Philip Shaw
We have a limited understanding of why many children with attention deficit hyperactivity disorder do not outgrow the disorder by adulthood. Around 20-30% retain the full syndrome as young adults, and about 50% show partial, rather than complete, remission. Here, to delineate the neurobiology of this variable outcome, we ask if the persistence of childhood symptoms into adulthood impacts on the brain's functional connectivity. We studied 205 participants followed clinically since childhood. In early adulthood, participants underwent magnetoencephalography (MEG) to measure neuronal activity directly and functional MRI (fMRI) to measure hemodynamic activity during a task-free period (the "resting state")...
October 16, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29076800/neurodegeneration-of-brain-networks-in-the-amyotrophic-lateral-sclerosis-frontotemporal-lobar-degeneration-als-ftld-continuum-evidence-from-mri-and-meg-studies
#11
Francesca Trojsi, Pierpaolo Sorrentino, Giuseppe Sorrentino, Gioacchino Tedeschi
Brain imaging techniques, especially those based on magnetic resonance imaging (MRI) and magnetoencephalography (MEG), have been increasingly applied to study multiple large-scale distributed brain networks in healthy people and neurological patients. With regard to neurodegenerative disorders, amyotrophic lateral sclerosis (ALS), clinically characterized by the predominant loss of motor neurons and progressive weakness of voluntary muscles, and frontotemporal lobar degeneration (FTLD), the second most common early-onset dementia, have been proven to share several clinical, neuropathological, genetic, and neuroimaging features...
October 27, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/29071979/-effect-of-electroacupuncture-stimulation-of-acupoints-of-heart-meridian-on-brain-connectivity-in-27-healthy-volunteer-subjects
#12
Wen-Ying Shi, Ping Li, Xiao-Rong Chang, Bi-Dan Lou, Jin-Xiang Li, Jie Huang, Lei Fan, Rong Luo, Ding Liu, Wei Zhang
OBJECTIVE: To observe the changes of brain rest-state functional connectivity following electroacupuncture (EA) stimulation of right Xia-Jiquan (HT 1), Shaohai (HT 3), Lingdao (HT 4) and Shenmen (HT 7) of the Heart Meridian and non-acupoints in healthy volunteers so as to provide an imaging basis for clinical treatment of some related disorders. METHODS: A total of 20 healthy volunteers who met the inclusion criteria were randomly divided into HT-acupoint group (n=10 cases) and non-acupoint group (n=10 cases) according to the visiting sequence...
June 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29070666/multiparametric-mri-changes-persist-beyond-recovery-in-concussed-adolescent-hockey-players
#13
Kathryn Y Manning, Amy Schranz, Robert Bartha, Gregory A Dekaban, Christy Barreira, Arthur Brown, Lisa Fischer, Kevin Asem, Timothy J Doherty, Douglas D Fraser, Jeff Holmes, Ravi S Menon
OBJECTIVE: To determine whether multiparametric MRI data can provide insight into the acute and long-lasting neuronal sequelae after a concussion in adolescent athletes. METHODS: Players were recruited from Bantam hockey leagues in which body checking is first introduced (male, age 11-14 years). Clinical measures, diffusion metrics, resting-state network and region-to-region functional connectivity patterns, and magnetic resonance spectroscopy absolute metabolite concentrations were analyzed from an independent, age-matched control group of hockey players (n = 26) and longitudinally in concussed athletes within 24 to 72 hours (n = 17) and 3 months (n = 14) after a diagnosed concussion...
October 25, 2017: Neurology
https://www.readbyqxmd.com/read/29068256/longitudinal-evaluation-of-resting-state-connectivity-white-matter-integrity-and-cortical-thickness-in-stable-hiv-infection-preliminary-results
#14
Diogo G Corrêa, Nicolle Zimmermann, Nina Ventura, Gustavo Tukamoto, Thomas Doring, Sarah Cb Leite, Rochele P Fonseca, Paulo Rv Bahia, Fernanda Cr Lopes, Emerson L Gasparetto
Purpose The objectives of this study were to determine if HIV-infected patients treated with highly active antiretroviral therapy (HAART), without dementia, suffer from longitudinal gray matter (GM) volume loss, changes in white matter (WM) integrity and deterioration in functional connectivity at rest, in an average interval of 30 months. Methods Clinically stable HIV-positive patients (on HAART, CD4 + T lymphocyte > 200 cells/μl, and viral loads <50 copies/μl) were recruited. None of them had HIV-associated dementia...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/29065364/effects-of-behavioral-activation-on-default-mode-network-connectivity-in-subthreshold-depression-a-preliminary-resting-state-fmri-study
#15
Satoshi Yokoyama, Yasumasa Okamoto, Koki Takagaki, Go Okada, Masahiro Takamura, Asako Mori, Syouichi Shiota, Naho Ichikawa, Ran Jinnin, Shigeto Yamawaki
BACKGROUND: Subthreshold depression is a risk factor for major depressive disorder, and it is known to have a negative impact on quality of life (QOL). Although behavioral activation, which is one type of cognitive behavioral therapy, is an effective psychological intervention for subthreshold depression, neural mechanisms of behavioral activation are unclear. Enhanced functional connectivity between default mode network (DMN) and the other regions has been demonstrated in participants with subthreshold depression...
October 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29065207/cerebellar-gray-matter-reductions-associate-with-decreased-functional-connectivity-in-nicotine-dependent-individuals
#16
Zhujing Shen, Peiyu Huang, Chao Wang, Wei Qian, Yihong Yang, Minming Zhang
Introduction: Nicotine dependence (ND) is a chronic, relapsing mental disorder characterized by compulsive cigarette seeking and smoking. Although the cerebellum plays an increasingly implicated role in ND, the exact cerebellar alterations in ND remain unclear. Identifying the localization of these cerebellar abnormalities in ND may help to further understand the role of the cerebellum in ND. Thus, we investigated the structural and functional alterations in the cerebellum in a large sample of smokers using the spatially unbiased infratentorial template (SUIT)...
July 27, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29064008/paediatric-population-neuroimaging-and-the-generation-r-study-the-second-wave
#17
Tonya White, Ryan L Muetzel, Hanan El Marroun, Laura M E Blanken, Philip Jansen, Koen Bolhuis, Desana Kocevska, Sabine E Mous, Rosa Mulder, Vincent W V Jaddoe, Aad van der Lugt, Frank C Verhulst, Henning Tiemeier
Paediatric population neuroimaging is an emerging field that falls at the intersection between developmental neuroscience and epidemiology. A key feature of population neuroimaging studies involves large-scale recruitment that is representative of the general population. One successful approach for population neuroimaging is to embed neuroimaging studies within large epidemiological cohorts. The Generation R Study is a large, prospective population-based birth-cohort in which nearly 10,000 pregnant mothers were recruited between 2002 and 2006 with repeated measurements in the children and their parents over time...
October 24, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/29060892/sensorimotor-network-parcellation-for-pre-surgical-patients-using-low-pass-filtered-fmri
#18
Hao Han, Yuxiang Yan, Wenjing Zhou, Bo Hong
Pre-surgical mapping of sensorimotor and language functions is crucial to reduce neurological deficits in epilepsy and tumor resection surgery. As non-invasive mapping, both resting-state and task-evoked functional MRI has been explored in pre-surgical mapping. In lack of standardized test paradigm, the reliability of fMRI mapping is still a concern for clinical use. In this study, to improve the reliability of fMRI based mapping, task fMRI data from all available task paradigms (motor movement, word repeating and picture naming) were low-pass filtered in the band of resting-state fMRI (0...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29057860/resting-state-fmri-findings-in-patients-with-first-episode-idiopathic-epilepsy-before-and-after-treatment
#19
Peng-Fei Qiao, Guang-Ming Niu
OBJECTIVE: To detect resting-state functional MRI (rsfMRI) changes and their relationships with the clinical curative effect of anti-epileptic drugs (AEDs) for complex partial seizures (CPS) in epilepsy patients using the fractional amplitude of low frequency fluctuation (fALFF). METHODS: rfMRI data from 14 CPS patients enrolled between June 2015 and June 2016 in Department of Neurology, Affiliated Hospital of Inner Mongolia Medical University were retrospectively investigated and compared with findings from 14 healthy age-, gender-, handedness-, and education-matched subjects...
October 2017: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/29057631/functional-connectivity-of-the-hippocampus-in-early-and-vs-late-onset-alzheimer-s-disease
#20
Kee Hyung Park, Young Noh, Eun Jung Choi, Hyungsik Kim, Sohyun Chun, Young Don Son
BACKGROUND AND PURPOSE: Early-onset Alzheimer's disease (EOAD) and late-onset Alzheimer's disease (LOAD) have different clinical and neuroimaging characteristics, but memory decline is usually present in both types. However, there have been few functional studies focused on the hippocampus in Alzheimer's disease. We therefore investigated the functional connectivity between the hippocampus and other brain regions using resting-state fMRI and compared the findings between EOAD and LOAD...
October 2017: Journal of Clinical Neurology
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