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https://www.readbyqxmd.com/read/28285865/application-of-the-strengthening-the-reporting-of-observational-studies-in-epidemiology-strobe-statement-to-publications-on-endoscopic-treatment-for-vesicoureteral-reflux
#1
M K Farrugia, A J Kirsch
OBJECTIVE: Following an increasing number of submissions on endoscopic treatment of vesicoureteral reflux (VUR), the Journal of Pediatric Urology sought to establish a quality guideline that would enable reviewers to select the best papers for publication in the journal. The "Strengthening the Reporting of Observational Studies in Epidemiology" (STROBE) Statement, established in 2007, is a 22-item checklist designed to assist with clear reporting of observational studies. This checklist includes a description of methodological items and instructions on how to use them to transparently report observational studies...
February 17, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28277235/variation-in-the-level-of-detail-in-pediatric-voiding-cystourethrogram-reports
#2
Anthony J Schaeffer, Jeanne S Chow, Anastasia Ivanova, Gang Cui, Saul P Greenfield, J Michael Zerin, Alejandro Hoberman, Ranjiv I Mathews, Tej K Mattoo, Myra A Carpenter, Marva Moxey-Mims, Russell W Chesney, Caleb P Nelson
INTRODUCTION: Voiding cystourethrogram (VCUG) provides a wealth of data on urinary tract function and anatomy, but few standards exist for reporting VCUG findings. OBJECTIVE: We aimed to assess variability in VCUG reports and to test our hypothesis that VCUG reports from pediatric facilities and pediatric radiologists are more complete than those performed at other facilities or by non-pediatric radiologists. STUDY DESIGN: We analyzed original VCUG reports from children enrolled in the Randomized Intervention for Children with Vesicoureteral Reflux (RIVUR) trial...
October 8, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28275518/laparoscopic-re-implantation-of-refluxing-ureter-in-children-a-feasibility-study
#3
Haytham E Badawy, Khaled Refaai, Ashraf S Soliman, Samir S Orabi
OBJECTIVE: To report our initial experience in the application of laparoscopy in the management of children with unilateral vesico-ureteric reflux (VUR) using the laparoscopic extravesical transperitoneal approach following the Lich-Gregoir technique, and to evaluate the results and benefits of this technique for such patients. PATIENTS AND METHODS: Between February 2013 and August 2014, 17 children [13 girls and four boys, with a median (range) age of 60 (24-120) months] presented with recurrent febrile urinary tract infections and were diagnosed with unilateral VUR...
March 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/28275513/extending-indications-of-micropercutaneous-nephrolithotomy-it-is-not-just-about-cracking-stones
#4
Arvind P Ganpule, Jaspreet Singh Chhabra, S B Sudharsan, Ankush Jairath, Mohankumar Vijaykumar, Ravindra Sabnis, Mahesh R Desai
OBJECTIVE: To describe our experience and results of using the MicroPerc™ micropercutaneous nephrolithotomy armamentarium (PolyDiagnost, Germany) for unusual indications unexplored using this modality. PATIENTS AND METHODS: We used the MicroPerc™ system for stone clearance in three ureteric calculi, two bladder calculi, one case of urethral calculus, for antegrade biopsy in a case of upper tract urothelial carcinoma, for Deflux® (dextranomer/hyaluronic copolymer, Salix Pharmaceuticals, Uppsala, Sweden) injection in three cases of vesico-ureteric reflux (VUR), and three cases of posterior urethral valve (PUV) fulgurations...
March 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/28270956/voiding-cystourethrogram-how-much-should-we-be-selective
#5
Sibel Yel, Sebahat Tülpar, Ruhan Düşünsel, Hakan Muammer Poyrazoğlu, İsmail Dursun, Ümmühan Abdülrezzak, Zübeyde Gündüz, Kenan Yılmaz, Funda Baştuğ
OBJECTIVE: In this study, we examined the patients' characteristics, who underwent voiding cystourethrography (VCUG), in order to determine any selectivity for indication of this invasive method. MATERIAL AND METHODS: After exclusion of indications of neurogenic bladder or antenatal hydronephrosis and control VCUGs, 159 VCUGs performed in our clinic within one year were evaluated. Patients are divided into three groups accoding to age. Clinical characteristic and findings of renal ultrasonography (US) and renal scintigraphy were examined...
March 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28265323/bladder-and-bowel-dysfunction-in-children-an-update-on-the-diagnosis-and-treatment-of-a-common-but-underdiagnosed-pediatric-problem
#6
REVIEW
Joana Dos Santos, Roberto I Lopes, Martin A Koyle
Bladder and bowel dysfunction (BBD) describes a spectrum of lower urinary symptoms (LUTS) accompanied by fecal elimination issues that manifest primarily by constipation and/or encopresis. This increasingly common entity is a potential cause of significant physical and psychosocial burden for children and families. BBD is commonly associated with vesicoureteral reflux (VUR) and recurrent urinary tract infections (UTIs), which at its extreme may lead to renal scarring and kidney failure. Additionally, BBD is frequently seen in children diagnosed with behavioural and neuropsychiatric disorders such as attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD)...
January 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28265312/antibiotic-prophylaxis-for-patients-with-prenatal-hydronephrosis-and-vesicoureteral-reflux-vur-no-one-recipe-for-all
#7
Julie Franc-Guimond
No abstract text is available yet for this article.
January 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28265311/continuous-antibiotic-prophylaxis-in-the-setting-of-prenatal-hydronephrosis-and-vesicoureteral-reflux
#8
REVIEW
Nathan C Wong, Martin A Koyle, Luis H Braga
Continuous antibiotic prophylaxis (CAP) has traditionally been offered for children with recurrent urinary tract infections (UTIs) or those at risk, including children diagnosed with prenatal hydronephrosis (HN) and vesicoureteral reflux (VUR). However, indications for antibiotic prophylaxis are controversial, data on who should benefit from this therapy is conflicting and, thus, guidelines are unable to provide conclusive recommendations. In the setting of prenatal HN, although randomized trials are currently underway, most evidence is derived from low- to moderate-quality observational studies...
January 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28265309/vesicoureteral-reflux-from-prophylaxis-to-surgery
#9
REVIEW
Anne-Sophie Blais, Stéphane Bolduc, Katherine Moore
Vesicoureteral reflux (VUR) is one of the most common pathologies encountered in pediatric urology. Better understanding of the evolution of VUR and new endoscopic surgical techniques in the last decades have led to major changes in the management of this pathology. However, the treatment algorithm remains complex and is composed of a wide variety of options, from active surveillance to surgical treatment. Herein, we propose to review treatment options for VUR in order to help clinicians make the right treatment decision for the right patient...
January 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28256423/validation-of-the-ureteral-diameter-ratio-for-predicting-early-spontaneous-resolution-of-primary-vesicoureteral-reflux
#10
Angela M Arlen, Andrew J Kirsch, Traci Leong, Christopher S Cooper
INTRODUCTION AND OBJECTIVE: Management of primary vesicoureteral reflux (VUR) remains controversial, and reflux grade currently constitutes an important prognostic factor. Previous reports have demonstrated that distal ureteral diameter ratio (UDR) may be more predictive of outcome than vesicoureteral reflux (VUR) grade. We performed an external validation study in young children, evaluating early spontaneous resolution rates relative to reflux grade and UDR. STUDY DESIGN: Voiding cystourethrograms (VCUGs) were reviewed...
February 14, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28243965/parent-compliance-a-bad-predictor-of-resolution-and-a-problem-in-the-application-of-eau-guidelines-on-vesicoureteral-reflux-in-children
#11
Radu Alexandru Prisca, Horea Gozar, Ana Maria Prisca, Cosmin Moldovan, Angela Borda
Primary vesicoureteral reflux (VUR) is a controversial pathology. Current management of VUR is ruled by EAU guidelines elaborated in 2012. They defined and analyzed the risk factors and enunciated three risk groups, developing the initial treatment indications. Continuous antibiotic prophylaxis (CAP) is recommended as the initial treatment option in patients classified in moderate-risk group without low urinary tract disorder. The compliance with medication use is a concern for using CAP. The aim of the present study is to quantify the compliance of the parents of VUR patients, to analyze its impact on treatment and the applicability of EAU guidelines in our patients...
February 27, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28215835/the-swedish-infant-high-grade-reflux-trial-uti-and-renal-damage
#12
Josefin Nordenström, Sofia Sjöström, Ulla Sillén, Rune Sixt, Per Brandström
INTRODUCTION: High-grade vesicoureteral reflux (VUR) in children is associated with recurrent urinary tract infection (UTI) and renal damage. Breakthrough UTI despite continuous antibiotic prophylaxis (CAP) during the first years of life is a matter of concern and evokes early intervention. We investigated whether early endoscopic treatment (ET) of VUR grade 4-5 can reduce the risk of UTI recurrence and renal scarring. MATERIALS AND METHODS: This prospective, randomized, controlled, multicentre, 1-year follow-up trial comprised 77 infants, <8 months of age with VUR grade 4-5 (Table) randomized to CAP (n = 39) or ET (with prophylaxis until resolution) (n = 38)...
February 2, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28215834/time-to-resolution-a-prospective-evaluation-from-the-society-for-fetal-urology-hydronephrosis-registry
#13
R S Zee, C D Anthony Herndon, C S Cooper, C Kim, P H McKenna, A Khoury, K W Herbst
INTRODUCTION: The resolution rate of prenatal urinary tract dilation (UTD) has been documented in several retrospective studies. The present study analyzed prospective observational registry data, with the aim of determining time to resolution among patients prenatally identified with mild postnatal UTD. MATERIALS AND METHODS: A total of 248 subjects, from four centers, were prospectively enrolled from 2008 to 2015. Exclusion criteria included other anomalies (n = 69), fewer than two ultrasounds, and/or <3 months follow-up (n = 26)...
January 19, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28215830/initial-urological-evaluation-and-management-of-children-with-neurogenic-bladder-due-to-myelomeningocele
#14
Cristian Sager, Carol Burek, Juan Pablo Corbetta, Santiago Weller, Javier Ruiz, Ramiro Perea, Enrique Lago, Yesica Gomez, Victor Durán, Juan Carlos López
INTRODUCTION: The proactive management of children with myelomeningocele (MMC) has contributed to decreasing their progression to end-stage renal disease, thanks to early urological evaluation and timing implementation of treatments. OBJECTIVE: To demonstrate that early urological evaluation of the urinary tract in MMC shows functional alterations in most cases, and that it requires medical intervention, even when in some cases the complementary imaging studies do not show any abnormalities...
January 30, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28195356/efficacy-of-onabotulinum-toxin-a-injection-in-pediatric-patients-with-non-neurogenic-detrusor-overactivity
#15
Omer Bayrak, Erkan Sadioglu, Haluk Sen, Kazim Dogan, Sakip Erturhan, Ilker Seckiner
AIMS: To evaluate the effectiveness and reliability of onabotulinum toxin A (onaBoNT-A) injections in pediatric patients with non-neurogenic detrusor overactivity (NNDO). METHODS: Between January 2010 and February 2016, 39 patients underwent onaBoNT-A injections for NNDO, and were evaluated retrospectively. Three-day voiding diary was filled at baseline, and at the postoperative 9th month. The voiding frequency, incontinence episodes, and the cystometric capacity were noted...
February 14, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28191787/urinary-excretion-of-egf-and-mcp-1-in-children-with-vesicoureteral-reflux
#16
Valentina Pastore, Fabio Bartoli
PURPOSE: The aim of this study was to investigate the urinary concentration of epidermal growth factor (EGF) and monocyte chemotactic protein-1 (MCP-1) as reflux nephropathy (RN) biomarkers before and after endoscopic treatment of moderate to severe vesico-ureteral reflux (VUR). MATERIALS AND METHODS: A prospective study was carried out on 72 children with moderate to severe VUR. All patients underwent endoscopic treatment using Macroplastique ® or Deflux®. Vesico-ureteral reflux resolution was tested by post-operative voiding cystourethrography after 3 months and 2 years...
February 10, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28169298/the-value-of-delta-neutrophil-index-in-young-infants-with-febrile-urinary-tract-infection
#17
Jung Won Lee, Seong Heon Kim, Se Jin Park, Keum Hwa Lee, Jae Hyon Park, Andreas Kronbichler, Michael Eisenhut, Ji Hong Kim, Jong Wook Lee, Jae Il Shin
Delta neutrophil index (DNI) is the fraction of circulating immature granulocytes, which reflects severe bacterial infections and septic condition but has not been studied in urinary tract infection (UTI). Here, we evaluated the value of DNI in predicting acute pyelonephritis (APN) or vesicoureteral reflux (VUR) using the data of 288 patients. Conventional inflammatory markers (white blood cell [WBC] count, erythrocyte sedimentation rate [ESR], C-reactive protein [CRP]), and DNI were measured. WBC, CRP, ESR and DNI were higher in APN than in lower UTI (p < 0...
February 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28164035/proximal-ureteral-atresia-a-rare-congenital-anomaly-incidental-finding-a-case-report
#18
Cosimo Bleve, Maria Luisa Conighi, Lorella Fasoli, Valeria Bucci, Francesco Battaglino, Salvatore Fabio Chiarenza
Ureteral atresia is a rare disease usually associated with a non-functioning dysplastic kidney. The condition may be unilateral or bilateral; focal, short or long and may involve any part of the ureter. Association with other urinary anomalies is rare. We report the case of a 10-month-old boy with prenatal diagnosis of multicystic right kidney. This suspicion was confirmed after birth by ultrasound and static scintigraphy; a right vesicoureteral reflux (VUR) was recorded at cystography. The boy presented a regular renal function but was hospitalized twice for suspected pyelonephritis between the 8th and the 10th month of life and were recorded occasional mild changes in blood pressure...
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28161229/-secondary-megaureter-a-rare-complication-of-deflux-%C3%A2-endoscopic-management-of-vesicoureteral-reflux-in-children
#19
N Boudaoud, A Line, M Pons, F Lefebvre, M A Bouche Pillon, C Francois, M L Poli Merol
Endoscopic management is the gold standard for symptomatic low-grade vesicoureteral reflux (VUR) in children. Deflux(®) (hyaluronic acid/dextranomer) injection is highly effective and has very few complications. We report on two cases of secondary megaureter after Deflux(®) injections. In the first case, a boy presented with Grade 4 VUR. He received a bilateral Deflux(®) injection with a total of three syringes. The postoperative ultrasound was normal. However, a check-up ultrasound 3 years later showed a significant ureteropyelocalyceal dilatation, with stasis and decreased renal function on scintigraphy, the reason why antireflux surgery (Cohen procedure) was performed...
February 1, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28159527/cystometrogram-appearance-in-puv-is-reliably-quantified-by-the-shape-wall-reflux-and-diverticuli-swrd-score-and-presages-the-need-for-intervention
#20
A Niyogi, K Lumpkins, A Robb, L McCarthy
OBJECTIVE: Radiological bladder abnormalities in boys with posterior urethral valves (PUV) are well recognised; however, the assessment is subjective. The shape, wall, reflux and diverticuli (SWRD) score objectively assesses shape, wall, reflux and diverticuli in a simple way. This study was undertaken to demonstrate that the SWRD score is reliable, reproducible and correlates with bladder outcome and videourodynamic (VUD) assessment in boys with PUV. MATERIALS AND METHODS: Three blinded assessors determined the SWRD scores of PUV bladders from cystometrograms taken during VUD from September 2012 to October 2013...
January 12, 2017: Journal of Pediatric Urology
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