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Nancy M Lee, Cevat Erisken, Thomas Iskratsch, Michael Sheetz, William N Levine, Helen H Lu
Physiologically relevant models of wound healing are essential for understanding the biology of connective tissue repair and healing. They can also be used to identify key cellular processes and matrix characteristics critical for the design of soft tissue grafts. Modeling the various stages of repair post tendon injury, polymer meshes of varying fiber diameter (nano-1 (390 nm) < nano-2 (740 nm) < micro (1420 nm)) were produced. Alignment was also introduced in the nano-2 group to model matrix undergoing biological healing rather than scar formation...
October 12, 2016: Biomaterials
A Wood, E B Haga, V A Costa, M N Rossi
Bruchine beetles are highly host-specific seed feeders during the larval stage. Although some specific parasitoid families have been recorded attacking bruchine beetles, most studies have been done at small spatial scales. Therefore, the current knowledge about the diversity and the geographic distribution of parasitoid species parasitizing bruchines is scarce, especially at a wide geographic area that extends over large distances through a latitudinal cline (i.e. large-scale spatial structure). The present study determined the species richness and evenness of parasitoids attacking the bruchine beetle Acanthoscelides macrophthalmus feeding on Leucaena leucocephala seeds, examined their geographic distribution, and characterized the large-scale spatial structure in parasitoid species composition...
October 21, 2016: Bulletin of Entomological Research
R Sood, C Kuhle, E Kapoor, J Rullo, J Thielen, K Frohmader, K Mara, D Schroeder, S Faubion
OBJECTIVES: To assess the association between the type of symptom and women's self-reported view of menopause. METHODS: The study was conducted at Mayo Clinic, Rochester MN, between January 2006 and October 2014. Women aged 40-64 were included. Data from 1420 women were analyzed in a cross-sectional design. The Menopause Health Questionnaire was used for symptom assessment. Odds ratios (ORs) and population attributable risk (PAR) (OR × percent frequency) were calculated for each symptom...
October 20, 2016: Climacteric: the Journal of the International Menopause Society
Lars Eisen, Nicole E Breuner, Andrias Hojgaard, J Charles Hoxmeier, Mark A Pilgard, Adam J Replogle, Brad J Biggerstaff, Marc C Dolan
Borrelia mayonii, a recently recognized species within the Borrelia burgdorferi sensu lato complex, has been detected in host-seeking Ixodes scapularis Say ticks and found to be associated with Lyme disease in the Upper Midwest. This spirochete has, to date, not been documented from the Northeast, but we previously demonstrated that I. scapularis ticks originating from Connecticut are capable of serving as a vector of B. mayonii In this follow-up study, we compared the vector efficiency for B. mayonii (strain MN14-1420) of I...
September 28, 2016: Journal of Medical Entomology
Yan Choi Lam, Harry B Gray, Jay R Winkler
Intersystem crossing (ISC) in solid [(C4H9)4N]4[Pt2(μ-P2O5(BF2)2)4], abbreviated Pt(pop-BF2), is remarkably slow for a third-row transition metal complex, ranging from τISC ≈ 0.9 ns at 310 K to τISC ≈ 29 ns below 100 K. A classical model based on Boltzmann population of one temperature-independent and two thermally activated pathways was previously employed to account for the ISC rate behavior. An alternative we prefer is to treat Pt(pop-BF2) ISC quantum mechanically, using expressions for multiphonon radiationless transitions...
October 6, 2016: Journal of Physical Chemistry. A
Meng Wu, Jianfang Lou, Shuping Zhang, Xian Chen, Lei Huang, Ruihong Sun, Peijun Huang, Shiyang Pan, Fang Wang
OBJECTIVES: The aim of this study was to investigate a possible mechanism of CD8(+) regulatory T-cell (Treg) production in an ovarian cancer (OC) microenvironment. MATERIALS AND METHODS: Agilent microarray was used to detect changes in gene expression between CD8(+) T cells cultured with and without the SKOV3 ovarian adenocarcinoma cell line. QRT-PCR was performed to determine glycolysis gene expression in CD8(+) T cells from a transwell culturing system and OC patients...
September 19, 2016: Cell Proliferation
Grant Theron, Jonny Peter, Marty Richardson, Rob Warren, Keertan Dheda, Karen R Steingart
BACKGROUND: Genotype® MTBDRsl (MTBDRsl) is a rapid DNA-based test for detecting specific mutations associated with resistance to fluoroquinolones and second-line injectable drugs (SLIDs) in Mycobacterium tuberculosis complex. MTBDRsl version 2.0 (released in 2015) identifies the mutations detected by version 1.0, as well as additional mutations. The test may be performed on a culture isolate or a patient specimen, which eliminates delays associated with culture. Version 1.0 requires a smear-positive specimen, while version 2...
September 8, 2016: Cochrane Database of Systematic Reviews
Mitali Khodani, Pooja Bansal, Raja Narayanan, Jay Chhablani
AIM: To assess the anatomical and visual outcome of idiopathic macular holes greater than 1000 µm using the inverted internal limiting membrane flap technique. METHODS: This retrospective case series included 5 eyes of 5 patients with idiopathic macular hole with base diameter greater than 1000 µm who underwent inverted internal limiting membrane flap technique along with standard 23G pars plans vitrectomy with posterior hyaloid detachment and fluid gas exchange with 12%-14% perfluoropropane (C3F8)...
2016: International Journal of Ophthalmology
Olufemi Desalu, Cajetan Onyedum, Emmanuel Sanya, Joseph Fadare, Adekunle Adeoti, Fatai Salawu, Rotimi Oluyombo, Micheal Olamoyegun, Micheal Fawale, Babajide Gbadegesin, Hamzat Bello
BACKGROUND: Obstructive sleep apnoea is the most common form of sleep-disordered breathing in adults and children. It is associated with many adverse health consequences. The objectives this study were to determine the prevalence, awareness and reporting of symptoms of obstructive sleep apnoea among hospitalized adult patients in Nigeria. METHODS: This was a multicenter cross-sectional study involving 1420 adult patients admitted to general medical and surgical wards of selected hospitals from March to April 2013...
July 2016: Ethiopian Journal of Health Sciences
Bobbi S Pritt, Laurel B Respicio-Kingry, Lynne M Sloan, Martin E Schriefer, Adam J Replogle, Jenna Bjork, Gongping Liu, Luke C Kingry, Paul S Mead, David F Neitzel, Elizabeth Schiffman, Diep K Hoang Johnson, Jeffrey P Davis, Susan M Paskewitz, David Boxrud, Alecia Deedon, Xia Lee, Tracy K Miller, Michelle A Feist, Christopher R Steward, Elitza S Theel, Robin Patel, Cole L Irish, Jeannine M Petersen
Lyme borreliosis (LB) is a multisystem disease caused by spirochetes in the Borrelia burgdorferi sensu lato (Bbsl) genospecies complex. We previously described a novel Borrelia species (type strain MN14-1420T) that causes LB among patients with exposures to ticks in the upper midwestern United States. Patients infected with the novel species demonstrated high levels of spirochetemia and differing clinical symptoms as compared to other Bbsl genospecies. The organism was detected from human specimens using polymerase chain reaction, microscopy, serology and culture...
August 24, 2016: International Journal of Systematic and Evolutionary Microbiology
Mame T Bakhoum, Assane G Fall, Moussa Fall, Chiavaroli K Bassene, Thierry Baldet, Momar T Seck, Jérémy Bouyer, Claire Garros, Geoffrey Gimonneau
BACKGROUND: Certain biting midges species of the genus Culicoides (Diptera: Ceratopogonidae) are vectors of virus to livestock worldwide. Culicoides larval ecology has remained overlooked because of difficulties to identify breeding sites, methodological constraints to collect samples and lack of morphological tools to identify field-collected individuals to the species level. After the 2007 unforeseen outbreaks of African horse sickness virus (AHSV) in Senegal (West Africa), there is a need to identify suitable and productive larval habitats in horse farms for the main Culicoides species to evaluate the implementation of vector control measures or preventive actions...
2016: Parasites & Vectors
Doris Hagan, Deliwe R Phethlu
OBJECTIVE: To describe factors that influence parents' decisions on childhood immunisations at Kumasi Metropolis in Ghana. STUDY DESIGN: Quantitative cross-sectional survey. METHODS: A sample of 303 parents was obtained from a monthly accessible population of 1420 individuals from the five district hospitals through convenience sampling of respondents at immunisation sessions in Kumasi. Data obtained from the survey were analysed with SPSS version 21 software...
2016: Curationis
Jonathan R Dillman, Ethan A Smith, Ramon Sanchez, Jeremy Adler, Soudabeh Fazeli, Bin Zhang, Matthew S Davenport
OBJECTIVE: The purpose of this study was to determine prospectively whether bowel wall apparent diffusion coefficient (ADC) measurements can be used to monitor treatment response to infliximab therapy in the setting of pediatric small-bowel Crohn disease. SUBJECTS AND METHODS: Twenty-eight pediatric subjects with newly diagnosed biopsy-proven Crohn disease of the distal or terminal ileum treated with infliximab were enrolled. Subjects underwent MR enterography at baseline, 1 month after therapy, and 6 months after therapy...
November 2016: AJR. American Journal of Roentgenology
Yohan Sahraoui, Céline Clauzel, Jean-Christophe Foltête
The aesthetic potential of landscape has to be modelled to provide tools for land-use planning. This involves identifying landscape attributes and revealing individuals' landscape preferences. Landscape aesthetic judgments of individuals (n = 1420) were studied by means of a photo-based survey. A set of landscape visibility metrics was created to measure landscape composition and configuration in each photograph using spatial data. These metrics were used as explanatory variables in multiple linear regressions to explain aesthetic judgments...
October 1, 2016: Journal of Environmental Management
Anubha Bilgaiyan, Tejendra Dixit, Gaurav Kapil, Shyam S Pandey, Shuji Hayase, Iyamperumal Anand Palani, Vipul Singh
We report the structural and optoelectronic properties of Zinc oxide (ZnO) nanostructures prepared by hydrothermal method. The morphological, structural and optical properties of the grown ZnO nanostructures were investigated using X-ray diffraction (XRD), scanning electron microscope (SEM) and photoluminescence spectroscopy (PL) respectively. Upon addition of relatively small amount of KI during the in-situ hydrothermal growth the nanorods were formed, further increasing the concentration led to increased diameter of these nanorods and finally at relatively higher concentration of KI, ZnO nanosheets were formed...
April 2016: Journal of Nanoscience and Nanotechnology
Marisa Pulcrano, Stephen R T Evans, Michael Sosin
Importance: Establishing strategies to minimize the burden of burnout and poor quality of life (QOL) on surgeons relies on a thorough understanding of QOL and burnout among the various surgical specialties. Objectives: To systematically review the literature across multiple surgical specialties and provide a comprehensive understanding of QOL and burnout among all surgeons, to delineate variation in rates of burnout and poor QOL, and to elucidate factors that are commonly implicated in these outcomes...
July 13, 2016: JAMA Surgery
Fatma Yurt Lambrecht, Mine Ince, Ozge Er, Kasim Ocakoglu, Cagla Kayabasi, Cumhur Gunduz, Fatma Aslıhan Sarı
Pancreatic cancer is very common and difficult to diagnose in early stage. Imaging systems for diagnosing cancer have many disadvantages. However, combining different imaging modalities offer synergistic advantages. Optical imaging is the most multidirectional and widely used imaging modality in both clinical practice and research. In present study, Zinc(II) phthalocyanine [Zn(II)Pc] was synthesized, labeled with iodine-131 and in vitro study was carried out. The intracellular uptake studies of radiolabeled Zn(II)Pc were performed in WI-38 [ATCC CCL-75™, tissue: human fibroblast lung] and MIA PaCa-2 [ATCC CRL-1420™, tissue: human epithelial pancreas carcinoma] cell lines...
June 27, 2016: Current Radiopharmaceuticals
Carolyn Cardona, Nanna Meyer, Margaret Harris, Nancy Di'Marco, Anthony Duplanty, Shawn Hueglin, Emilia Ochoa
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Maria A Spyrou, Rezeda I Tukhbatova, Michal Feldman, Joanna Drath, Sacha Kacki, Julia Beltrán de Heredia, Susanne Arnold, Airat G Sitdikov, Dominique Castex, Joachim Wahl, Ilgizar R Gazimzyanov, Danis K Nurgaliev, Alexander Herbig, Kirsten I Bos, Johannes Krause
Ancient DNA analysis has revealed an involvement of the bacterial pathogen Yersinia pestis in several historical pandemics, including the second plague pandemic (Europe, mid-14(th) century Black Death until the mid-18(th) century AD). Here we present reconstructed Y. pestis genomes from plague victims of the Black Death and two subsequent historical outbreaks spanning Europe and its vicinity, namely Barcelona, Spain (1300-1420 cal AD), Bolgar City, Russia (1362-1400 AD), and Ellwangen, Germany (1485-1627 cal AD)...
June 8, 2016: Cell Host & Microbe
Hongxian Liu, Kai Huang, Shuyuan Liu, Hao Sun, Keqin Lin, Xiaoqin Huang, Jiayou Chu, Zhaoqing Yang
OBJECTIVE: The aim of this study was to determine the distribution and origin of hemoglobin E (HbE) in seven minority groups from various geographical regions of the malaria-endemic Yunnan province, southwestern China, which have similar ethnic origins and geographic relationships with HbE-prevalent populations of Southeast Asian countries. METHODS: By using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) methods, the prevalence of HbE was examined in 1488 individuals from seven native minority groups of Yunnan, and β-globin gene cluster haplotypes were determined on 1420 chromosomes...
June 6, 2016: American Journal of Human Biology: the Official Journal of the Human Biology Council
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