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https://www.readbyqxmd.com/read/28087432/stenting-after-coiling-using-a-single-microcatheter-for-treatment-of-ruptured-intracranial-fusiform-aneurysms-with-parent-arteries-less-than-1-5-mm-in-diameter
#1
Jian Liu, Yisen Zhang, Yang Wang, Shiqing Mu, Xinjian Yang
BACKGROUND: Ruptured intracranial fusiform aneurysms involving small-diameter parent arteries are difficult to treat. Parent artery occlusion is a relatively simple and reliable treatment. However, occasionally, the parent arteries have to be retained. The arrival of the low-profile stent (LVIS(TM) Jr.) has made reconstructive endovascular treatment for fusiform aneurysms involving small-diameter parent arteries possible. CASE DESCRIPTION: This report describes an innovative method for stent-assisted coiling (stenting after coiling technique using only one microcatheter), and describes our initial experience and feasibility of this technique...
January 10, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28086905/reduction-of-eddy-current-losses-in-inductive-transmission-systems-with-ferrite-sheets
#2
Matthias Maaß, Andreas Griessner, Viktor Steixner, Clemens Zierhofer
BACKGROUND: Improvements in eddy current suppression are necessary to meet the demand for increasing miniaturization of inductively driven transmission systems in industrial and biomedical applications. The high magnetic permeability and the simultaneously low electrical conductivity of ferrite materials make them ideal candidates for shielding metallic surfaces. For systems like cochlear implants the transmission of data as well as energy over an inductive link is conducted within a well-defined parameter set...
January 5, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28076368/functional-laterality-of-task-evoked-activation-in-sensorimotor-cortex-of-preterm-infants-an-optimized-3-t-fmri-study-employing-a-customized-neonatal-head-coil
#3
Lukas Scheef, Jurek A Nordmeyer-Massner, Adam Pr Smith-Collins, Nicole Müller, Gaby Stegmann-Woessner, Jacob Jankowski, Jürgen Gieseke, Mark Born, Hermann Seitz, Peter Bartmann, Hans H Schild, Klaas P Pruessmann, Axel Heep, Henning Boecker
BACKGROUND: Functional magnetic resonance imaging (fMRI) in neonates has been introduced as a non-invasive method for studying sensorimotor processing in the developing brain. However, previous neonatal studies have delivered conflicting results regarding localization, lateralization, and directionality of blood oxygenation level dependent (BOLD) responses in sensorimotor cortex (SMC). Amongst the confounding factors in interpreting neonatal fMRI studies include the use of standard adult MR-coils providing insufficient signal to noise, and liberal statistical thresholds, compromising clinical interpretation at the single subject level...
2017: PloS One
https://www.readbyqxmd.com/read/28070839/-1-h-and-31-p-myocardial-magnetic-resonance-spectroscopy-in-non-obstructive-hypertrophic-cardiomyopathy-patients-and-competitive-athletes
#4
Francesco Secchi, Giovanni Di Leo, Marcello Petrini, Riccardo Spairani, Marco Alì, Marco Guazzi, Francesco Sardanelli
PURPOSE: The clinical differentiation between athlete's heart and mild forms of non-obstructive hypertrophic cardiomyopathy (HCM) is crucial. We hypothesized that differences do exist between the myocardial metabolism of patients with non-obstructive HCM and competitive athletes (CAs). Our aim was to evaluate myocardial metabolism with (31)P-MRS and (1)H-MRS in HCM patients and CAs. MATERIALS AND METHODS: After Ethics Committee approval, 15 CAs and 7 HCM patients were prospectively enrolled...
January 9, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28068389/cooperative-interactions-between-different-classes-of-disordered-proteins-play-a-functional-role-in-the-nuclear-pore-complex-of-baker-s-yeast
#5
David Ando, Ajay Gopinathan
Nucleocytoplasmic transport is highly selective, efficient, and is regulated by a poorly understood mechanism involving hundreds of disordered FG nucleoporin proteins (FG nups) lining the inside wall of the nuclear pore complex (NPC). Previous research has concluded that FG nups in Baker's yeast (S. cerevisiae) are present in a bimodal distribution, with the "Forest Model" classifying FG nups as either di-block polymer like "trees" or single-block polymer like "shrubs". Using a combination of coarse-grained modeling and polymer brush modeling, the function of the di-block FG nups has previously been hypothesized in the Di-block Copolymer Brush Gate (DCBG) model to form a higher-order polymer brush architecture which can open and close to regulate transport across the NPC...
2017: PloS One
https://www.readbyqxmd.com/read/28063817/pulse-sequence-considerations-for-simulation-and-postimplant-dosimetry-of-prostate-brachytherapy
#6
Jingfei Ma, Marinus A Moerland, Aradhana M Venkatesan, Tharakeswara K Bathala, Rajat J Kudchadker, Kristy K Brock, Steven J Frank
PURPOSE: The purpose of this work is to present a brief review of MRI physics principles pertinent to prostate brachytherapy, and a summary of our experience in optimizing protocols for prostate brachytherapy applications. METHODS AND MATERIALS: We summarized essential MR imaging characteristics and their interplays that need to be considered for prostate brachytherapy applications. These include spatial resolution, signal-to-noise ratio, image contrast, artifacts, geometric distortion, specific absorption rate, and total scan time...
January 4, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28063106/excitability-of-the-motor-cortex-in-patients-with-migraine-changes-with-the-time-elapsed-from-the-last-attack
#7
Francesca Cortese, Gianluca Coppola, Davide Di Lenola, Mariano Serrao, Cherubino Di Lorenzo, Vincenzo Parisi, Francesco Pierelli
BACKGROUND: Motor-evoked potentials (MEPs) produced by single-pulse transcranial magnetic stimulation (TMS) of the motor cortex can be an objective measure of cortical excitability. Previously, MEP thresholds were found to be normal, increased, or even reduced in patients with migraine. In the present study, we determined whether the level of cortical excitability changes with the time interval from the last migraine attack, thereby accounting for the inconsistencies in previous reports...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28062990/ultrastructural-aspects-and-molecular-phylogeny-of-auerbachia-maamouni-n-sp-myxosporea-bivalvulida-from-the-gallbladder-of-gnathanodon-speciosus-forssk%C3%A3-l-actinopterygii-carangidae-in-the-red-sea
#8
Lamjed Mansour, Carlos Azevedo, Ângela Alves, Saleh Al-Quraishy, Abdel-Azeem S Abdel-Baki
A new myxosporean parasite, Auerbachia maamouni n. sp., infecting the gallbladder of the golden trevally Gnathanodon speciosus Forsskål, is described, based on morphology, ultrastructure, and small subunit (SSU) rRNA gene sequencing. Of 50 fish collected from the Red Sea in Jeddah, Saudi Arabia, five were found heavily infected with mature myxospores floating free in the bile. Mature spores are pyriform to club-shaped with smooth valves, and contain a single polar capsule with an S-shaped polar filament, arranged in 13-16 polar filament coils, oriented longitudinally, with an irregular distribution on the polar capsule matrix...
January 2017: Systematic Parasitology
https://www.readbyqxmd.com/read/28059107/single-cell-time-lapse-analysis-reveals-that-podoplanin-enhances-cell-survival-and-colony-formation-capacity-of-squamous-cell-carcinoma-cells
#9
Tomoyuki Miyashita, Youichi Higuchi, Motohiro Kojima, Atsushi Ochiai, Genichiro Ishii
Tumor initiating cells (TICs) are characterized by high clonal expansion capacity. We previously reported that podoplanin is a TIC-specific marker for the human squamous cell carcinoma cell line A431. The aim of this study is to explore the molecular mechanism underlying the high clonal expansion potential of podoplanin-positive A431cells using Fucci imaging. Single podoplanin-positive cells created large colonies at a significantly higher frequency than single podoplanin-negative cells, whereas no difference was observed between the two types of cells with respect to cell cycle status...
January 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28057589/microsurgical-clipping-of-unruptured-intracranial-aneurysms-a-single-surgeon-s-experience-over-sixteen-years
#10
Anil Nanda, Devi Prasad Patra, Shyamal C Bir, Tanmoy K Maiti, Piyush Kalakoti, Papireddy Bollam
INTRODUCTION: Unruptured intracranial aneurysms (UIA) have become an issue of greater significance as their detection rates have increased over the years. We present the overall experience of microsurgical clipping of unruptured aneurysms by a single surgeon over a period of more than 16 years. METHODS: The clinical and radiological data were retrospectively reviewed. Clinical outcome at follow-up was assessed by Glasgow Outcome Scale (GOS), and angiograms were reviewed for the degree of occlusion...
January 2, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28048818/su-f-i-65-fatty-acid-quantification-in-high-fat-diet-induced-abnormal-intrahepatic-triglyceride-storage-using-internal-standard-method-at-3-0-t
#11
K-H Song, C-H Yoo, S-I Lim, B-Y Choe
PURPOSE: The objective of this study was to determine the metabolic changes in a rat model of high-fat-diet-induced non-alcoholic fatty liver disease (NAFLD) by using single-voxel 1H-MRS with a 3.0 T MRI scanner. METHODS: The examination were performed on a 3.0T scanner using a 4-channel animal coil for higher resolution. This method used point-resolved spectroscopy (PRESS) (repetition time (TR)/echo time (TE) = 6000/35 ms; number of signal averages (NSA) = 64)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048807/su-g-iep1-02-automated-snr-analysis-of-mr-images-using-model-based-noise-determination
#12
K Krugh
PURPOSE: To develop a robust automated method of signal-to-noise (SNR) analysis from MR images using a single image acquisition approach and model-based noise determination. METHODS: Three consecutive MRI phantom scans were performed according to the SNR test procedures in the 2015 ACR MRI Quality Control Manual. This was repeated for several different RF coils and on MRI scanners from two different vendors. The three images from each RF coil were analyzed by the single-image (SNR-ACR1) and two-image (SNR-ACR2) SNR analysis methods also described in the ACR QC Manual...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047531/su-g-iep1-15-towards-accurate-cerebral-blood-flow-quantification-with-distortion-corrected-pseudo-continuous-arterial-spin-labeling
#13
M Hoff, S Rane-Levandovsky, J Andre
PURPOSE: Traditional arterial spin labeling (ASL) acquisitions with echo planar imaging (EPI) readouts suffer from image distortion due to susceptibility effects, compromising ASL's ability to accurately quantify cerebral blood flow (CBF) and assess disease-specific patterns associated with CBF abnormalities. Phase labeling for additional coordinate encoding (PLACE) can remove image distortion; our goal is to apply PLACE to improve the quantitative accuracy of ASL CBF in humans. METHODS: Four subjects were imaged on a 3T Philips Ingenia scanner using a 16-channel receive coil with a 21/21/10cm (frequency/phase/slice direction) field-of-view...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045071/magnetic-resonance-microscopy-mrm-of-single-mammalian-myofibers-and-myonuclei
#14
Choong H Lee, Niclas Bengtsson, Stephen M Chrzanowski, Jeremy J Flint, Glenn A Walter, Stephen J Blackband
Recently, the first magnetic resonance microscopy (MRM) images at the cellular level in isolated mammalian brain tissues were obtained using microsurface coils. These methods can elucidate the cellular origins of MR signals and describe how these signals change over the course of disease progression and therapy. In this work, we explore the capability of these microimaging techniques to visualize mouse muscle fibers and their nuclei. Isolated myofibers expressing lacZ were imaged with and without a stain for β-galactosidase activity (S-Gal + ferric ammonium citrate) that produces both optical and MR contrast...
January 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28040909/mri-surface-coil-pair-with-strong-inductive-coupling
#15
Richard R Mett, Jason W Sidabras, James S Hyde
A novel inductively coupled coil pair was used to obtain magnetic resonance phantom images. Rationale for using such a structure is described in R. R. Mett et al. [Rev. Sci. Instrum. 87, 084703 (2016)]. The original rationale was to increase the Q-value of a small diameter surface coil in order to achieve dominant loading by the sample. A significant improvement in the vector reception field (VRF) is also seen. The coil assembly consists of a 3-turn 10 mm tall meta-metallic self-resonant spiral (SRS) of inner diameter 10...
December 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28040784/genetic-analysis-of-the-lambda-spanins-rz-and-rz1-identification-of-functional-domains
#16
Jesse Cahill, Manoj Rajaure, Chandler O'Leary, Jordan Sloan, Armando Marrufo, Ashley Holt, Aneesha Kulkarni, Oscar Hernandez, Ry Young
Coliphage lambda proteins Rz and Rz1 are the inner membrane and outer membrane subunits of the spanin complex, a heterotetramer that bridges the periplasm and is essential for the disruption of the outer membrane during phage lysis. Recent evidence suggests the spanin complex functions by fusing the inner and outer membrane. Here we use a genetics approach to investigate and characterize determinants of spanin function. Because Rz1 is entirely embedded in the +1 reading frame of Rz, the genes were dis-embedded before using random mutagenesis to construct a library of lysis-defective alleles for both genes...
December 30, 2016: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28040269/comparison-of-the-peak-resolution-and-the-stationary-phase-retention-between-the-satellite-and-the-planetary-motions-using-the-coil-satellite-centrifuge-with-counter-current-chromatographic-separation-of-4-methylumbelliferyl-sugar-derivatives
#17
Kazufusa Shinomiya, Kazumasa Zaima, Yukina Harada, Miho Yasue, Naoki Harikai, Koji Tokura, Yoichiro Ito
Coil satellite centrifuge (CSC) produces the complex satellite motion consisting of the triplicate rotation of the coiled column around three axes including the sun axis (the angular velocity, ω1), the planet axis (ω2) and the satellite axis (the central axis of the column) (ω3) according to the following formula: ω1=ω2+ω3. Improved peak resolution in the separation of 4-methylumbelliferyl sugar derivatives was achieved using the conventional multilayer coiled columns with ethyl acetate/1-butanol/water (3: 2: 5, v/v) for the lower mobile phase at the combination of the rotation speeds (ω1, ω2, ω3)=(300, 150, 150rpm), and (1:4:5, v/v) for the upper mobile phase at (300:100:200rpm)...
January 20, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28038746/self-assembly-of-acetylated-dextran-with-various-acetylation-degrees-in-aqueous-solutions-studied-by-light-scattering
#18
Isala Dueramae, Masaru Yoneyama, Naoki Shinyashiki, Shin Yagihara, Rio Kita
Self-assembly of acetylated dextran (Ac-DEXs) was investigated with a modified dextran with acetic anhydride in the presence of pyridine. The effect of acetylation degree on solution properties has been investigated by static and dynamic light scattering (DLS). Molecular weight (Mw) and the radius of gyration (Rg) of dextran significantly increased with acetylation degree due to the aggregates formation. However, those aggregates noticeably reduced with further increase of acetylation degree. It suggested that the aggregates have shrinkage...
March 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28034580/canadian-cardiovascular-society-canadian-heart-rhythm-society-2016-implantable-cardioverter-defibrillator-guidelines
#19
Matthew Bennett, Ratika Parkash, Pablo Nery, Mario Sénéchal, Blandine Mondesert, David Birnie, Laurence D Sterns, Claus Rinne, Derek Exner, François Philippon, Debra Campbell, Jafna Cox, Paul Dorian, Vidal Essebag, Andrew Krahn, Jaimie Manlucu, Franck Molin, Michael Slawnych, Mario Talajic
Sudden cardiac death is a major public health issue in Canada. However, despite the overwhelming evidence to support the use of implantable cardioverter defibrillators (ICDs) in the prevention of cardiac death there remains significant variability in implantation rates across Canada. Since the most recent Canadian Cardiovascular Society position statement on ICD use in Canada in 2005, there has been a plethora of new scientific information to assist physicians in their discussions with patients considered for ICD implantation to prevent sudden cardiac death due to ventricular arrhythmias...
October 6, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28029593/pulse-width-affects-scalp-sensation-of-transcranial-magnetic-stimulation
#20
Angel V Peterchev, Bruce Luber, Gregory G Westin, Sarah H Lisanby
BACKGROUND: Scalp sensation and pain comprise the most common side effect of transcranial magnetic stimulation (TMS), which can reduce tolerability and complicate experimental blinding. OBJECTIVE: We explored whether changing the width of single TMS pulses affects the quality and tolerability of the resultant somatic sensation. METHODS: Using a controllable pulse parameter TMS device with a figure-8 coil, single monophasic magnetic pulses inducing electric field with initial phase width of 30, 60, and 120 µs were delivered in 23 healthy volunteers...
October 6, 2016: Brain Stimulation
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