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https://www.readbyqxmd.com/read/28644003/chemical-sensor-based-upon-stress-induced-changes-in-the-permeability-of-a-magnetoelastic-wire
#1
Nahla A Hatab, Nichole A Crane, David K Mee, L Neville Howell, Larry R Mooney, Russell L Hallman, Michael J Sepaniak, Vincent E Lamberti
We introduce a chemical sensing technology, named ChIMES (Chemical Identification through Magneto-Elastic Sensing), that can detect a broad range of targets and that has the capability of untethered communication through a metallic or nonmetallic barrier. These features enable many applications in which penetrations into the sampled environment are unwanted or infeasible because of health, safety, or environmental concerns, such as following the decomposition of a dangerous material in a sealed container. The sensing element is passive and consists of a target response material hard-coupled to a magnetoelastic wire...
June 23, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28639791/insight-into-the-final-step-of-the-supramolecular-buildup-of-eumelanin
#2
Anne Büngeler, Benjamin Hämisch, Klaus Huber, Wolfgang Bremser, Oliver Ingolf Strube
The final step in the supramolecular buildup of eumelanin particles is investigated regarding involved species and mechanism. Time resolved in situ light scattering and scanning electron microscopy reveal an aggregation of particles with narrow size distribution around 40 nm, previously only observed as substructures. These form larger particles with again very uniform size and diameters around 200 nm. Aggregation of each single particle takes only a few minutes to complete, whereas the entire process goes on for at least three hours, partly due to kinetics of the precursors...
June 22, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28632306/analytical-modeling-provides-new-insight-into-complex-mutual-coupling-between-surface-loops-at-ultrahigh-fields
#3
N I Avdievich, A Pfrommer, I A Giapitzakis, A Henning
Ultrahigh-field (UHF) (≥7 T) transmit (Tx) human head surface loop phased arrays improve both the Tx efficiency (B1(+) /√P) and homogeneity in comparison with single-channel quadrature Tx volume coils. For multi-channel arrays, decoupling becomes one of the major problems during the design process. Further insight into the coupling between array elements and its dependence on various factors can facilitate array development. The evaluation of the entire impedance matrix Z for an array loaded with a realistic voxel model or phantom is a time-consuming procedure when performed using electromagnetic (EM) solvers...
June 20, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28629619/slow-interconversion-in-a-heterogeneous-unfolded-state-ensemble-of-outer-membrane-phospholipase-a
#4
Georg Krainer, Pablo Gracia, Erik Frotscher, Andreas Hartmann, Philip Gröger, Sandro Keller, Michael Schlierf
Structural and dynamic investigations of unfolded proteins are important for understanding protein-folding mechanisms as well as the interactions of unfolded polypeptide chains with other cell components. In the case of outer-membrane proteins (OMPs), unfolded-state properties are of particular physiological relevance, because these proteins remain unfolded for extended periods of time during their biogenesis and rely on interactions with binding partners to support proper folding. Using a combination of ensemble and single-molecule spectroscopy, we have scrutinized the unfolded state of outer-membrane phospholipase A (OmpLA) to provide a detailed view of its structural dynamics on timescales from nanoseconds to milliseconds...
June 16, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28622656/a-combined-experimental-setup-for-op-and-odnmr
#5
Erika L Sesti, Matthew M Willmering, Zayd L Ma, Dustin D Wheeler, Mark S Conradi, Sophia E Hayes
Instrumentation for optically-pumped and optically-detected nuclear magnetic resonance (OPNMR and ODNMR) has been developed and implemented as a single experimental apparatus to study semiconductors such as GaAs and CdTe. These two measurement schemes use many of the same components for experiments. Here we describe, in two parts, the apparatus that can record such measurements and give examples of representative data. In Part 1, the radio-frequency probe and low-temperature cryostat are described, including single-channel and two-channel static cryogenic probes that both incorporate a modified solenoid coil that permits better optical access...
June 7, 2017: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/28622420/technical-note-comparison-of-megavoltage-dual-energy-and-single-energy-ct-based-%C3%AE-maps-for-a-4-channel-breast-coil-in-pet-mri
#6
John C Patrick, R Terry Thompson, Aaron So, John Butler, David Faul, Robert Z Stodilka, Slav Yartsev, Frank S Prato, Stewart Gaede
PURPOSE: The purpose of this study was to describe and evaluate methods for calculating a megavoltage computed tomography (MVCT) derived MR hardware attenuation map (μ-map) and dual-energy CT (DECT) for 511 keV photons. METHODS: Phantom measurements were acquired on a whole-body hybrid PET/MRI system, using a four-channel receive-only MR radiofrequency (RF) breast coil. Two acquisitions were performed: with the phantoms positioned in the four-channel RF breast coil, and without the breast coil...
June 16, 2017: Medical Physics
https://www.readbyqxmd.com/read/28616928/-clinical-study-of-rs-epi-dwi-to-improve-imaging-quality-and-assessment-on-intracranial-mass-lesions
#7
Kai Zhang, Chun-Chao Xia, Qiang Yue, Tao Guo, Wan-Lin Peng, Yu-Ming Li, Lei Li, Fei Zhao, Jin Pu, Qi Leng, Zhen-Lin Li
OBJECTIVES: To explore the clinical value of readout-segmented echo planar imaging (Rs-EPI) sequence in the assessment of intracranial mass lesions compared to the standard single-shot EPI (Ss-EPI) sequence. METHODS: We included 21 patients with intracranial mass lesions who underwent both Ss-EPI diffusion weighted imaging (DWI) and Rs-EPI DWI at 3.0T MR scanner with a twenty-channel head-neck coil. The quality of images was assessed by two experienced radiologists independently...
May 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28606549/molecular-weight-and-helix-conformation-determine-intestinal-anti-inflammatory-effects-of-exopolysaccharide-from-schizophyllum-commune
#8
Bin Du, Yuedong Yang, Zhaoxiang Bian, Baojun Xu
Intestinal anti-inflammatory activities of exopolysaccharide from S. commune were assessed using dextran sulfate sodium (DSS)-induced colitis in mice model. The changes of molecular weight (MW), atomic force microscope morphology, X-ray diffraction, particle size distribution, and viscosity were recorded after sonication treatment. The results indicated that the triple helical structure of exopolysaccharide was dissociated into single helical structure and random coiled structure by ultrasonication via breaking of inter- and intramolecular hydrogen bonds...
September 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28606255/-incidence-and-risk-factors-of-recurrence-after-endovascular-treatment-of-vertebrobasilar-dissecting-aneurysms
#9
Y Z Zang, Z G Wang, C W Wang, Y Zhang, X Ding, X F Wang
Objective: To evaluate the incidence and risk factors of recurrence after endovascular treatment of vertebrobasilar dissecting aneurysms (VBDAs). Methods: Retrospective analysis was used for the clinical information of 40 cases of vertebrobasilar dissecting aneurysms treated with endovascular methods in our department between January 2007 and December 2015.According to whether recurrence occurred, the patients were divided into recurrence group (10 patients) and non-recurrence group (30 patients). The data of the patients' age, sex, hypertension history, smoking history, aneurismal size, presenting symptoms, degree of embolization, GCS scores, aneurismal localization and treatment methods were analyzed to evaluate the risk factors for recurrence after endovascular treatment...
June 6, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28603934/model-based-t1-mapping-with-sparsity-constraints-using-single-shot-inversion-recovery-radial-flash
#10
Xiaoqing Wang, Volkert Roeloffs, Jakob Klosowski, Zhengguo Tan, Dirk Voit, Martin Uecker, Jens Frahm
PURPOSE: To develop a model-based reconstruction technique for single-shot T1 mapping with high spatial resolution, accuracy, and precision using an inversion-recovery (IR) fast low-angle shot (FLASH) acquisition with radial encoding. METHODS: The proposed model-based reconstruction jointly estimates all model parameters, that is, the equilibrium magnetization, steady-state magnetization, 1/ T1*, and all coil sensitivities from the data of a single-shot IR FLASH acquisition with a small golden-angle radial trajectory...
June 11, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28602943/in-vivo-b0-field-shimming-methods-for-mri-at-7-t
#11
Jason P Stockmann, Lawrence L Wald
Functional MRI (fMRI) at 7 T and above provides improved Signal-to-Noise Ratio and Contrast-to-Noise Ratio compared to 3 T acquisitions. In addition to the beneficial effects on spin polarization and magnetization of deoxyhemoglobin, the increased applied field also further magnetizes air and tissue. While the magnets themselves typically provide a static B0 field with sufficient spatial homogeneity, the diamagnetism of tissue and the paramagnetism of air causes local field deviations inside the human head...
June 7, 2017: NeuroImage
https://www.readbyqxmd.com/read/28602898/endovascular-treatment-of-visceral-artery-pseudoaneurysms-psas-in-patients-with-chronic-pancreatitis-our-single-center-experience
#12
Daniela Gabrielli, Francesco Taglialatela, Cesare Mantini, Alberto Giammarino, Francesco Modestino, Antonio Raffaele Cotroneo
PURPOSE: to analyse our experience in endovascular treatment as first-line approach for severe and acute hemorrhage in patients with chronic pancreatitis. MATERIAL AND METHODS: from 2010 to 2016 at our institution 12 males (mean age 66 years) with bleeding pseudoaneurysms (PSAs) underwent urgent visceral angiography and endovascular treatment. All patients had chronic pancreatitis. True visceral artery aneurysms and PSAs arising after surgery were excluded from the study...
June 7, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28600229/the-structural-basis-of-alpha-tropomyosin-linked-asp230asn-familial-dilated-cardiomyopathy
#13
M L Lynn, L Tal Grinspan, T A Holeman, J Jimenez, J Strom, J C Tardiff
Recently, linkage analysis of two large unrelated multigenerational families identified a novel dilated cardiomyopathy (DCM)-linked mutation in the gene coding for alpha-tropomyosin (TPM1) resulting in the substitution of an aspartic acid for an asparagine (at residue 230). To determine how a single amino acid mutation in α-tropomyosin (Tm) can lead to a highly penetrant DCM we generated a novel transgenic mouse model carrying the D230N mutation. The resultant mouse model strongly phenocopied the early onset of cardiomyopathic remodeling observed in patients as significant systolic dysfunction was observed by 2months of age...
June 7, 2017: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/28598274/evaluation-of-ischemic-lesion-prevalence-after-endovascular-treatment-of-intracranial-aneurysms-as-documented-by-3-t-diffusion-weighted-imaging-a-2-year-single-center-cohort-study
#14
Christina Iosif, Jean-Christophe Lecomte, Eduardo Pedrolo-Silveira, George Mendes, Marie-Paule Boncoeur Martel, Suzana Saleme, Charbel Mounayer
OBJECTIVE Even though published data exist concerning the prevalence of ischemic lesions detected by diffusion-weighted imaging (DWI) following endovascular treatment of intracranial aneurysms, a single-center cross-evaluation of the different endovascular techniques has been lacking. The authors sought to prospectively evaluate the prevalence and clinical significance of ischemic lesions occurring after endovascular treatment of intracranial aneurysms and to compare the safety and effectiveness of a broad spectrum of currently accepted endovascular techniques in a single-center setting...
June 9, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28595331/the-use-of-single-stent-assisted-coiling-in-treatment-of-bifurcation-aneurysms-a-multicenter-cohort-study-with-proposal-of-a-scoring-system-to-predict-complete-occlusion
#15
Nimer Adeeb, Christoph J Griessenauer, Apar S Patel, Paul M Foreman, Carlos E Baccin, Justin M Moore, Raghav Gupta, Abdulrahman Alturki, Mark R Harrigan, Christopher S Ogilvy, Ajith J Thomas
BACKGROUND: The development of stent-assisted coiling has allowed for the endovascular treatment of wide-necked bifurcation aneurysms. A variety of options exist, and little is known about the optimal stent configuration in this setting. We report a large multicenter experience of stent-assisted coiling of bifurcations aneurysms using a single stent, with attention to factors predisposing to aneurysm recanalization. OBJECTIVE: To assess the safety and efficacy of single stent-assisted coiling, in addition to analyzing the factors associated with recanalization, and proposal of a predictive scoring scale...
June 8, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28593394/double-balloon-assisted-coil-embolization-bace-combined-with-proximal-and-distal-balloon-inflation-for-short-abdominal-arterial-segments-comparison-with-single-bace
#16
Mitsunari Maruyama, Takeshi Yoshizako, Tomonori Nakamura, Megumi Nakamura, Rika Yoshida, Shinji Ando, Hajime Kitagaki
PURPOSE: To evaluate the differences of technique between coil embolization for short abdominal arterial segments with only proximal balloon inflation and combined proximal and distal balloon inflation, as well as the volume embolization ratio (VER) and the ratio of the first coil diameter to the target vessel diameter (first coil diameter ratio). MATERIALS AND METHODS: From January 2014 to August 2016, we performed coil embolization of the short segment in seven patients...
June 7, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28587530/endovascular-treatment-of-wide-neck-intracranial-bifurcation-aneurysms-with-y-configuration-double-neuroform%C3%A2-stents-assisted-coiling-technique-experience-in-a-single-center
#17
C Castaño, M Terceño, S Remollo, M R García-Sort, C Domínguez
Background Intracranial wide-neck aneurysms at the arterial bifurcations, especially in the aneurysms where the bifurcating branches emanate directly from the base of the aneurysm, have been particularly difficult on which to perform endovascular treatment. The 'Y'-configuration, double stent-assisted coil embolization is an option for the treatment of these difficult aneurysms, allowing the closure of the aneurysm, preserving the parent arteries. Material and methods In a nine-year period, 546 intracranial aneurysms in 493 patients were treated at our center by endovascular approach...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28583450/intraprocedural-rupture-of-unruptured-cerebral-aneurysms-during-coil-embolization-a-single-center-experience
#18
Su Hee Cho, Mohammed Denewer, Won Hyong Park, Jae Sung Ahn, Byung Duk Kwun, DeokHee Lee, Jung Cheol Park
OBJECTIVE: The incidence of intraprocedural rupture (IPR) during endovascular coiling is reported to range from 2% to 5%. In this study, we reviewed the single center experiences of IPR during coil embolization for unruptured intracranial aneurysm. METHODS: At our institution, 849 patients were treated with endovascular therapy for unruptured intracranial aneurysm between January 2011 and April 2016. Ten (1.18%) of these patients had documented IPR. We reviewed the medical data to evaluate the characteristics of the aneurysms, angiographic findings related to rupture, management, and outcomes...
June 2, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28582441/in-vivo-mr-angiography-for-the-assessment-of-aortic-aneurysms-in-an-experimental-mouse-model-on-a-clinical-mri-scanner-comparison-with-high-frequency-ultrasound-and-histology
#19
Christian H P Jansen, Carolin Reimann, Julia Brangsch, René M Botnar, Marcus R Makowski
BACKGROUND: MR-angiography currently represents one of the clinical reference-standards for the assessment of aortic-dimensions. For experimental research in mice, dedicated preclinical high-field MRI scanners are used in most studies. This type of MRI scanner is not available in most institutions. The aim of this study was to evaluate the potential of MR-angiography performed on a clinical MR scanner for the assessment of aortic aneurysms in an experimental mouse model, compared to a preclinical high-resolution ultrasound imaging system and histopathology...
2017: PloS One
https://www.readbyqxmd.com/read/28572554/-die-symmetrie-von-spiralketten
#20
Ulrich Müller
In crystals, polymeric chain molecules often adopt helical structures. Neglecting small distortions possibly caused by an anisotropic environment within the crystal, the symmetry of the single helix can be described by a rod group, which has translational symmetry in one dimension. The rod groups have Hermann-Mauguin symbols similar to space groups, beginning with a script style \scr p followed by a screw-axis symbol; the order of the screw axis can adopt any value. In a crystal, the rod-site symmetry, the so-called penetration rod group, must be a common crystallographic rod subgroup of the molecular rod group and the space group...
June 1, 2017: Acta Crystallographica Section B, Structural Science, Crystal Engineering and Materials
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