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https://www.readbyqxmd.com/read/29772623/-a-case-of-seminal-vesicle-cyst-incidentally-diagnosed-during-rupture-of-abdominal-subcutaneous-abscess
#1
Shinya Somiya, Masahiro Tamaki, Shohei Fujikawa, Yuya Yamada, Yuki Kamiyama, Toshio Kanaoka
Seminal vesicle cyst is a rare disease and is often asymptomatic. We present a case of huge seminal vesicle cyst connected to the abdominal wall and observed as a subcutaneous abscess. An 89-year-old man presented with asymptomatic spontaneous rupture of the left lower abdominal subcutaneous abscess. Computed tomography (CT) showed a relatively low intensity cystic mass located in the Retzius' space just below the abscess, surrounding the right bladder wall laterally and connecting to the right seminal vesicle posteriorly...
April 2018: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29772077/a-feature-alignment-score-for-online-cone-beam-ct-based-image-guided-radiotherapy-for-prostate-cancer
#2
Catriona Hargrave, Timothy Deegan, Michael Poulsen, Tomasz Bednarz, Fiona Harden, Kerrie Mengersen
PURPOSE: To develop a method for scoring online cone-beam CT (CBCT)-to-planning CT image feature alignment to inform prostate image-guided radiotherapy (IGRT) decision-making. The feasibility of incorporating volume variation metric thresholds, predictive of delivering planned dose into weighted functions, was investigated. METHODS: Radiation therapists and radiation oncologists participated in workshops where they reviewed prostate CBCT-IGRT case examples and completed a paper-based survey of image feature matching practices...
May 17, 2018: Medical Physics
https://www.readbyqxmd.com/read/29772061/an-image-guided-radiotherapy-decision-support-framework-incorporating-a-bayesian-network-and-visualization-tool
#3
Catriona Hargrave, Timothy Deegan, Tomasz Bednarz, Michael Poulsen, Fiona Harden, Kerrie Mengersen
PURPOSE: To describe a Bayesian network (BN) and complementary visualization tool, that aim to support decision-making during online cone-beam computed tomography (CBCT)-based image guide radiotherapy (IGRT) for prostate cancer patients. METHODS: The BN was created to represent relationships between observed prostate, proximal seminal vesicle (PSV), bladder and rectum volume variations, an image feature alignment score (FASTV _ OAR ), delivered dose and treatment plan compliance (TPC)...
May 17, 2018: Medical Physics
https://www.readbyqxmd.com/read/29764692/combined-high-dose-rate-brachytherapy-and-external-beam-radiotherapy-for-clinically-localised-prostate-cancer
#4
Iosif Strouthos, Georgios Chatzikonstantinou, Nikolaos Zamboglou, Natasa Milickovic, Sokratis Papaioannou, Dimitra Bon, Constantinos Zamboglou, Claus Rödel, Dimos Baltas, Nikolaos Tselis
PURPOSE: To report the clinical outcomes and treatment-related toxicities after combined high-dose-rate (HDR) brachytherapy (BRT) with external beam radiotherapy (EBRT) for patients with clinically localised high-risk prostate cancer. MATERIAL AND METHODS: Between 2008 and 2012, three hundred and three consecutive patients with organ-confined high-risk prostate cancer were treated with definitive radiotherapy consisting of HDR-BRT followed by supplemental EBRT. The transrectal 3D-ultrasound-based HDR-BRT boost consisted of two single-fraction implants of 10...
May 12, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29757474/automated-patient-specific-transperineal-ultrasound-probe-setups-for-prostate-cancer-patients-undergoing-radiotherapy
#5
Saskia Maria Camps, Frank Verhaegen, Ben G L Vanneste, Peter H N de With, Davide Fontanarosa
PURPOSE: The use of ultrasound imaging is not widespread in prostate cancer radiotherapy workflows, despite several advantages (e.g. allowing real-time volumetric organ tracking). This can be partially attributed to the need for a trained operator during acquisition and interpretation of the images. We introduce and evaluate an algorithm that can propose a patient-specific transperineal ultrasound probe setup, based on a CT scan and anatomical structure delineations. The use of this setup during the simulation and treatment stage could improve usability of ultrasound imaging for relatively untrained operators (radiotherapists with less than one year experience with ultrasound)...
May 14, 2018: Medical Physics
https://www.readbyqxmd.com/read/29743042/predictors-of-adverse-pathologic-features-after-radical-prostatectomy-in-low-risk-prostate-cancer
#6
Jae Won Park, Dong Hoon Koh, Won Sik Jang, Kang Su Cho, Won Sik Ham, Koon Ho Rha, Sung Joon Hong, Young Deuk Choi
BACKGROUND: Prostate-specific antigen (PSA) screening more frequently detects early stage prostate cancer (PC). However, adverse pathologic features (APFs) after radical prostatectomy (RP) in low-risk PC occur. Previous related studies had utilized outdated staging criteria or small sample cohorts. In this study, we analyzed predictors of APFs after RP in low-risk PC using classification under the current criteria. MATERIALS AND METHODS: We retrospectively reviewed medical records of 546 low-risk PC patients who had undergone RP...
May 9, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29738172/-seminal-vesiculoscopy-past-status-quo-and-prospects
#7
Qi Wang, Liang-Gong Liao, Yan-Feng Li
Seminal vesiculoscopy is a new technology in uro-andrology developed in recent 10 years, which is a set of clinical operational techniques for observing the ejaculatory duct, seminal vesicle, ampullar region of the vas deferens and their surrounding structure, determining the cause, location and degree of the disease, and accomplishing such treatment procedures as irrigation, resection, incision, fulguration, hemostasis, expansion, drainage, and removal of hematocele, stones or obstruction in the distal seminal duct region...
November 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29734926/parastar-insecticide-induced-changes-in-reproductive-parameters-and-testicular-oxidative-stress-biomarkers-in-wistar-male-rats
#8
Edouard Akono Nantia, Antoine S Kada, Faustin Pt Manfo, Nehemiah N Tangu, Kaghou M Mbifung, Desire H Mbouobda, Augustave Kenfack
Parastar is an insecticide formulation of lambda-cyhalothrin and imidacloprid, and it is largely used for crop production improvement in Santa, North West Region of Cameroon. This study aimed at evaluating the effects of Parastar on reproductive parameters and testicular oxidative stress in adult albino Wistar male rats. Twenty rats (154 g ± 28 g) were divided into four groups of five animals each and treated daily with either distilled water (10 mL/kg), 1.25, 2.49 or 6.23 mg/kg of Parastar, respectively, for 35 days...
January 1, 2018: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/29730198/long-term-outcomes-after-deferred-radical-prostatectomy-in-men-initially-managed-by-active-surveillance
#9
Rebecka Arnsrud Godtman, Max Schafferer, Carl-Gustaf Pihl, Johan Stranne, Jonas Hugosson
PURPOSE: To determine the long-term outcomes after deferred radical prostatectomy. MATERIAL AND METHODS: The study population consisted of all men with screening-detected prostate cancer who underwent deferred radical prostatectomy (n=132; 1 Jan 1995-31 Dec 2014) after active surveillance in the Göteborg Randomized, Population-based Prostate Cancer Screening Trial. The last date of follow-up was 15 May 2017. Follow-up during active surveillance was performed with prostate-specific antigen (PSA)-tests every 3-6 months and repeat biopsies every 2-4 years...
May 3, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29726126/human-prostasomes-from-normozoospermic-and-non-normozoospermic-men-show-a-differential-protein-expression-pattern
#10
A García-Rodríguez, M de la Casa, H Peinado, J Gosálvez, R Roy
Prostasomes are exosomes such as extracellular vesicles, produced in the prostatic epithelium and released into the seminal plasma, that play an important role enhancing male fertility. Although some studies have demonstrated that prostasomes have a rich proteomic content, it is still unclear if that proteomic content varies depending on the male fertility status. Prostasomes from 12 normozoospermic and 14 non-normozoospermic seminal samples were isolated by differential ultracentrifugation. Protein content was studied by quantitative mass spectrometry and compared between both cohorts...
May 3, 2018: Andrology
https://www.readbyqxmd.com/read/29723459/-clinicopathological-features-of-primary-seminal-vesicle-adenocarcinoma-a-report-of-4-cases-and-review-of-the-literature
#11
Jia-Ning Guo, Hui Li, Zhan-Dong Hu, En-Li Liang, Ji-Wu Chang
Objective: To investigate the clinicopathological characteristics, diagnosis, and treatment of primary seminal vesicle adenocarcinoma (SVAC). METHODS: We analyzed the clinical data and clinicopathological characteristics of 4 cases of primary SVAC treated in the Department of Urology of the Second Hospital of Tianjin Medical University and reviewed relevant literature. RESULTS: All the 4 patients were treated by open radical resection of the seminal vesicle and prostate and pathologically diagnosed with SVAC...
July 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29720747/wnt-signaling-pathway-in-uterus-of-normal-and-seminal-vesicle-excised-mated-mice-during-pre-implantation-window
#12
Zeinab Latifi, Amir Fattahi, Kobra Hamdi, Aliye Ghasemzadeh, Pouran Karimi, Hamid Reza Nejabati, Marefat Ghaffari Novin, Leila Roshangar, Mohammad Nouri
Introduction: The importance of seminal vesicle secretion and uterine Wnt signaling for uterus preparation and embryo implantation has been described. Materials and Methods: In this study, we evaluated the gene expression of Wnt ligands (Wnt4 and Wnt5a) and their corresponding receptors (Fzd2 and Fzd6) using qRT-PCR and active β-catenin protein levels using western blotting in the uterine tissue of female mice mated with intact and seminal vesicle-excised (SVX) males during the pre-implantation window...
April 2018: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/29720516/seminal-siv-in-chronically-infected-cynomolgus-macaques-is-dominated-by-virus-originating-from-multiple-genital-organs
#13
Laurent Houzet, Marcos Pérez-Losada, Giulia Matusali, Claire Deleage, Nathalie Dereuddre-Bosquet, Anne-Pascale Satie, Florence Aubry, Emmanuelle Becker, Bernard Jégou, Roger Le Grand, Brandon F Keele, Keith A Crandall, Nathalie Dejucq-Rainsford
The sexual transmission of viruses is responsible for the spread of multiple infectious diseases. Although the HIV/AIDS pandemic remains fueled by sexual contacts with infected semen, the origin of virus in semen is still unknown. In a substantial number of HIV- infected men, viral strains present in semen differ from the ones in blood, suggesting that HIV is locally produced within the genital tract. Such local production may be responsible for the persistence of HIV in semen despite effective antiretroviral therapy...
May 2, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29709315/salvage-hdr-brachytherapy-multiple-hypothesis-testing-versus-machine-learning-analysis
#14
Gilmer Valdes, Albert J Chang, Yannet Interian, Kenton Owen, Shane T Jensen, Lyle H Ungar, Adam Cunha, Timothy D Solberg, I-Chow Hsu
PURPOSE: Salvage high-dose-rate brachytherapy (sHDRB) is a treatment option for recurrences after prior radiation therapy. However, only approximately 50% of patients benefit, with the majority of second recurrences after salvage brachytherapy occurring distantly. Therefore, identification of characteristics that can help select patients who may benefit most from sHDRB is critical. Machine learning may be used to identify characteristics that predict outcome following sHDRB. We aimed to use machine learning to identify patient characteristics associated with biochemical failure (BF) following prostate sHDRB...
March 13, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29707681/hershberger-assays-for-di-2-ethylhexyl-phthalate-and-its-substitute-candidates
#15
Hee-Su Kim, Yong-Pil Cheon, Sung-Ho Lee
In the present study, we employed Hershberger assay to determine possible androgenic or antiandrogenic activities of three di-2-ethylhexyl phthalate (DEHP) substitute candidates. The assay was carried out using immature castrated Sprague-Dawley male rats. After 7 days of the surgery, testosterone propionate (TP, 0.4 mg/kg/day) and test materials (low dose, 40 mg/kg/day; high dose, 400 mg/kg/day) were administered for 10 consecutive days by subcutaneous (s.c.) injection and oral gavage, respectively. Test materials were DEHP, 2-ethylhexyl oleate (IOO), 2-ethylhexyl stearate (IOS) and triethyl 2-acetylcitrate (ATEC)...
March 2018: Balsaeng'gwa Saengsig
https://www.readbyqxmd.com/read/29706418/seminal-plasma-differentially-alters-the-resistance-of-dog-ram-and-boar-spermatozoa-to-hypotonic-stress
#16
Guillaume Tsikis, Karine Reynaud, Stéphane Ferchaud, Xavier Druart
During ejaculation and the deposition in the female genital tract, spermatozoa undergo hypo-osmotic stress and need to withstand it for optimal fertility. Resistance to hypo-osmotic stress may be affected by the interaction of the spermatozoa with seminal fluid components. The hypo-osmotic resistance of epididymal and ejaculated spermatozoa from dogs, rams and boars was assessed by flow cytometric measurement of sperm viability after incubation in NaCl solutions with osmolalities ranging from 0 to 300 mmol/kg...
February 2, 2018: Animal Reproduction Science
https://www.readbyqxmd.com/read/29692359/seminal-fluid-metabolome-and-epididymal-changes-after-antibiotic-treatment-in-mice
#17
Cheryl Susan Rosenfeld, Angela B Javurek, Sarah A Johnson, Zhentian Lei, Lloyd W Summer, Rex A Hess
Paternal environment can induce detrimental developmental origins of health and disease (DOHaD) effects in resulting offspring and even future descendants. Such paternal-induced DOHaD effects might originate from alterations in a possible seminal fluid microbiome (SFM) and composite metabolome. Seminal vesicles secrete a slightly basic product enriched with fructose and other carbohydrates, providing an ideal habitat for microorganisms. Past studies confirm the existence of a SFM that is influenced by genetic and nutritional status...
April 24, 2018: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/29690004/a-new-species-of-temnocephala-platyhelminthes-with-an-unusual-pharynx-including-an-amendment-of-the-diagnosis-of-the-genus
#18
Rodrigo Ponce De leÓn, Odile Volonterio
Three species of Temnocephala have been reported on Aegla from Uruguay: Temnocephala axenos, Temnocephala mertoni and Temnocephala talicei. As part of a systematic review of the Uruguayan species of Temnocephala, a fourth species was found on Aegla platensis and Aegla uruguayana. This species, new for the genus, has the following diagnostic characters: Large temnocephalan; slightly curved penial stylet (225 µm in length) with a symmetrical introvert (27 long by 18 µm in diameter) that has at least 44 spine-like projections, each bearing 7 rows of internal spines; a seminal vesicle that opens sub-polarly into the contractile vesicle; a muscular vagina with a strong asymmetrical sphincter; preequatorial nephridiopores close to the internal borders of the elongate-oval excretory syncytia; a large pharynx with anterior and posterior sphincters of about the same diameter and a narrow pharyngeal lumen with nearly uniform width...
February 8, 2018: Zootaxa
https://www.readbyqxmd.com/read/29686966/a-rare-case-of-suspected-intravascular-large-b-cell-lymphoma-forming-nodular-masses-in-the-brain-and-around-the-prostate-and-seminal-vesicle
#19
Takuto Ogasawara, Yoshinori Ikehata, Ryuichi Kato, Noriomi Miyao, Yasuhiro Konishi, Shinichiro Kon
Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of diffuse large B-cell lymphoma (DLBCL). Furthermore, tumorigenesis is extremely rare. An 80-year-old man was admitted to our hospital with nervous symptoms. Imaging tests showed a brain tumor and mass lesions in the seminal vesicle and retroperitoneum. Transrectal biopsy of the seminal vesicle helped diagnose the patient with DLBCL. The patient's general status deteriorated rapidly, and he died on the 23rd day after admission. An autopsy was performed and the pathological diagnosis was DLBCL, specifically suspected as IVLBCL, with nodular masses in the brain and seminal vesicle...
May 2018: Urology Case Reports
https://www.readbyqxmd.com/read/29666266/dna-methylation-and-transcriptome-aberrations-mediated-by-er%C3%AE-in-mouse-seminal-vesicles-following-developmental-des-exposure
#20
Yin Li, Katherine J Hamilton, Tianyuan Wang, Laurel A Coons, Wendy N Jefferson, Ruifang Li, Yu Wang, Sara A Grimm, J Tyler Ramsey, Liwen Liu, Kevin E Gerrish, Carmen J Williams, Paul A Wade, Kenneth S Korach
Early transient developmental exposure to an endocrine active compound, diethylstilbestrol (DES), a synthetic estrogen, causes late-stage effects in the reproductive tract of adult mice. Estrogen receptor alpha (ERα) plays a role in mediating these developmental effects. However, the developmental mechanism is not well known in male tissues. Here, we present genome-wide transcriptome and DNA methylation profiling of the seminal vesicles (SVs) during normal development and after DES exposure. ERα mediates aberrations of the mRNA transcriptome in SVs of adult mice following neonatal DES exposure...
April 16, 2018: Proceedings of the National Academy of Sciences of the United States of America
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