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pica and dialysis

Zachary Z Brener, Michael Bergman
Pica refers to the persistent, compulsive craving for and ingestion of nonfood items and certain food items. Pica is quite common among dialysis patients. The nutrient composition of some of the substances ingested may contribute to severe metabolic and mineral disturbances and other serious medical complications. We report the first case of a hemodialysis patient with chalk pica associated hypercalcemia who developed acute necrotizing pancreatitis. Hydration, nutritional support and hemodialysis treatments with low-calcium bath led to clinical improvement and correction of his calcium...
August 2014: Clinical Kidney Journal
Maria Fusaro, Marianna Noale, Giovanni Tripepi, Sandro Giannini, Angela D'Angelo, Angelo Pica, Lorenzo A Calò, Davide Miozzo, Maurizio Gallieni
BACKGROUND: Proton pump inhibitors (PPIs) are a class of drugs that is extensively used for common gastrointestinal disorders and often prescribed long-term for years. Long-term PPI treatment is associated with an increased risk of fractures in the general population. Several studies have suggested a relationship between vascular calcification, which is a predictor of cardiovascular morbidity and mortality, impaired bone metabolism and fractures. In dialysis patients, vascular calcifications are widespread and are connected to bone health...
August 2013: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
Osasuyi Iyasere, Ying Allington, Michele Cafferkey
Maintaining fluid balance in haemodialysis patients is important because of the adverse effects of excessive interdialytic weight gain. This often requires fluid restriction that patients often struggle with. We report a case of a 31-year-old female diabetic patient on haemodialysis with repeated excessive interdialytic weight gains despite fluid restriction and dry weight adjustment. It was subsequently discovered that she devised an unusual, albeit unsuccessful, strategy of eating the polyurethane foam from her dialysis chair while increasing her fluid intake hoping that it would absorb excess water in the gut! This under-diagnosed phenomenon known as pica has been reported in renal patients with substances such as ice, clay and baking soda...
2010: BMJ Case Reports
Chryso Pefkaros Katsoufis, Myerly Kertis, Judith McCullough, Tanya Pereira, Wacharee Seeherunvong, Jayanthi Chandar, Gaston Zilleruelo, Carolyn Abitbol
OBJECTIVE: Pica is the compulsive consumption of non-nutritive substances, and this disorder may occur more frequently in dialysis patients. The purpose of our study was to determine the prevalence of pica and the associated demographic and metabolic characteristics. DESIGN: Retrospective, cross-sectional analysis. SETTING: Hospital-based, outpatient, pediatric hemodialysis unit. SUBJECTS: Eighty-seven pediatric patients on chronic dialysis therapy were interviewed...
November 2012: Journal of Renal Nutrition
O Bailon, P-Y Garcia, M Logak, S Timsit
INTRODUCTION: Wallenberg's syndrome and ipsilateral paresis due to combined infarction of the lateral medullary and cervical spinal infarction is known as Opalski syndrome. This rarely described syndrome was reported, to our knowledge, with DWI MRI, only once. CASE REPORT: We report the case of a 43-year-old man with autosomal dominant polycystic kidney disease who, after a brief episode of coma, developed Wallenberg syndrome and ipsilateral hemiparesis. Initial diffusion weighted-imaging MRI showed a high-intensity signal involving the lateral medulla oblongata and the spinal cord; but FLAIR MRI sequences showed bilateral high-intensity signals in the lateral medulla oblongata and spinal cord and high-intensity signals in the right and left cerebellar hemisphere in the PICA territories...
February 2011: Revue Neurologique
Livia Pica-Mattoccia, Daniele Carlini, Alessandra Guidi, Velasco Cimica, Fabio Vigorosi, Donato Cioli
Available evidence suggests that the antischistosomal drug oxamniquine is converted to a reactive ester by a schistosome enzyme that is missing in drug-resistant parasites. This study presents data supporting the idea that the active ester is a sulfate and the activating enzyme is a sulfotransferase. Evidence comes from the fact that the parasite extract loses its activating capability upon dialysis, implying the requirement of some dialyzable cofactor. The addition of the sulfate donor 3'-phosphoadenosine 5'-phosphosulfate (PAPS) restored activity of the dialyzate, a strong indication that a sulfotransferase is probably involved...
September 2006: Memórias do Instituto Oswaldo Cruz
Manish Garg, Mary Jo Shaver, Andrea Easom
No abstract text is available yet for this article.
April 2004: Nephrology News & Issues
C I Obialo, A K Crowell, X J Wen, A C Conner, E L Simmons
OBJECTIVE: Clay pica is a form of compulsive ingestion of non-nutritive substances frequently practiced by dialysis patients. Its consequences are unknown. In this study, we evaluated the effect of regular consumption of clay on hematologic and metabolic profiles in hemodialysis patients. DESIGN: A prospective, case-control study with use of structured questionnaire. SETTING: Free-standing hemodialysis units. PATIENTS: One hundred thirty-eight patients on hemodialysis for at least 12 months were interviewed...
January 2001: Journal of Renal Nutrition
P A Ward
No abstract text is available yet for this article.
January 2000: Seminars in Dialysis
P Ward, N G Kutner
In a prospective study, pica behavior was investigated during baseline interviews with a cohort of incident patients (n = 226) who began chronic dialysis therapy in metropolitan Atlanta, GA, during 1996 to 1997. Pica, defined as current pica behavior and/or reported history of pica behavior, was reported by 16% of the sample. Patients reporting pica were significantly more likely to be African American women and were significantly younger than the remainder of the sample. Approximately two thirds of patients who reported pica behaviors craved and excessively consumed ice; the remainder craved and consumed starch, dirt, flour, or aspirin...
January 1999: Journal of Renal Nutrition
J P Griffith, V K Bhanot
Geophagia, the deliberate ingestion of earth, is a serious clinical problem, particularly for dialysis patients. This article presents a geophagic patient with end stage renal disease and reviews the etiology, consequences and treatment of this disorder.
March 1994: West Virginia Medical Journal
D K Abu-Hamdan, J H Sondheimer, S K Mahajan
A male patient undergoing hemodialysis in whom the cause of severe hyperkalemia (more than 8 mmol/liter) was found to be an unusual pica is described. His pica consisted of ingestion of burnt match heads (cautopyreiophagia). The potassium content of his daily consumption of burnt matches added 80 mmol to his 45 mmol dietary potassium intake. Hypogeusia and hypozincemia were documented. Oral zinc supplementation (zinc sulfate 220 mg per day for 10 weeks) normalized his plasma zinc level and taste acuity. He abandoned his pica and his plasma potassium level dropped significantly to 5...
October 1985: American Journal of Medicine
L Pica-Mattoccia, D Cioli, S Archer
Hycanthone-sensitive and hycanthone-resistant schistosomes (which are also sensitive and resistant to oxamniquine) were exposed in vitro to tritium-labelled oxamniquine. The initial uptake of the drug into the schistosomes was essentially the same for the 2 strains. The homogenate of worms incubated with tritiated oxamniquine was fractionated and a purified DNA fraction was obtained by ethanol precipitation, RNAase and protease digestion, repeated phenolchloroform extractions, CsC1 gradient centrifugation and extensive dialysis...
May 1989: Transactions of the Royal Society of Tropical Medicine and Hygiene
J Duclos
Absolute or functional iron deficiency decreases the effectiveness of erythropoietin in patients undergoing hemodialysis. We describe a patient who developed pica associated to a ferritin level of 800 ng/ml during recombinant human erythropoietin treatment. The symptom subsided after supplementation with iron dextran. Therefore we recommend iron supplementation during the initial phase of treatment with erythropoietin until serum ferritin levels raise above 1000 ng/ml.
March 1992: Revista Médica de Chile
S H Armstrong, R F Kourany
No abstract text is available yet for this article.
December 1979: Journal of the Tennessee Medical Association
M Kensit
No abstract text is available yet for this article.
1979: Journal of the American Association of Nephrology Nurses & Technicians
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