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https://www.readbyqxmd.com/read/29655711/characterizations-of-the-endogenous-starch-hydrolase-inhibitors-in-acorns-of-quercus-fabri-hance
#1
Yi Lin, Yuyun Lu, Zhixuan Song, Dejian Huang
The acorns of Quercus fabri Hance tree, or the mandarin duck fruits have been consumed by locals in the form of noodle, yet there is little scientific study. We found that they have much lower digestibility compared with that of rice flour. Solvent extraction using hexane, dichloromethane, and acetone-ethanol-water (AEW) mixture yielded three fractions but the starch hydrolase inhibitors were only found in the AEW fraction. Using assay-guided fractionation of the extracts, we were able to further separate the active compounds by using Sephadex LH-20 column and characterize the inhibitor chemical identities by LC-MS( n ) ...
August 30, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29629525/high-dietary-glycemic-load-is-associated-with-poor-functional-outcome-in-patients-with-acute-cerebral-infarction
#2
Tae Jin Song, Yoonkyung Chang, Min Young Chun, Chan Young Lee, A Ram Kim, Yuri Kim, Yong Jae Kim
BACKGROUND AND PURPOSE: Elevated postprandial blood glucose is a critical risk factor for stroke. The dietary glycemic load (GL) and glycemic index (GI) are frequently used as markers of the postprandial blood glucose response to estimate the overall glycemic effect of diets. We hypothesized that high dietary GL, GI, or total carbohydrate intake is associated with a poor functional outcome in patients with acute ischemic stroke. METHODS: We prospectively included 263 first-ever ischemic stroke patients who completed a semiquantitative food-frequency questionnaire...
April 2018: Journal of Clinical Neurology
https://www.readbyqxmd.com/read/29618311/predicting-factors-affecting-glucose-monitoring-treatment-satisfaction-and-drug-attitude-inventory-adherence-among-patients-with-type-2-diabetes-mellitus-cross-sectional-observational-study
#3
Syed Ata Ur Rahman
OBJECTIVES: The study aimed to explore the predictors affecting patient satisfaction to glucose monitoring system (GMSS) and drug attitude inventory (DAI) / treatment adherence among type 2 diabetes mellitus patients. METHODS: Cross-sectional observational study design was used to conduct this study. Subjective assessments were made by questionnaires and objective data was collected from the patients' medication profiles registered to diabetic clinics. Patients were recruited from five different public hospitals of Hyderabad region, India...
April 4, 2018: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29617350/co-ingestion-of-rice-bran-soymilk-or-plain-soymilk-with-white-bread-effects-on-the-glycemic-and-insulinemic-response
#4
Stefan Gerardus Camps, Joseph Lim, Atsushi Ishikado, Yumi Inaba, Makoto Suwa, Motonobu Matsumoto, Christiani Jeyakumar Henry
The regular consumption of soy products is associated with inverse incidence of type 2 diabetes, and there has been an increasing interest in the glycemia reducing potential of rice bran and its components. In this study, we investigated whether consuming soymilk with the addition of rice bran (fiber) can reduce the glycemic response of a carbohydrate meal. Seventeen healthy Asian men (BMI: 18.5-29 kg/m²) participated in this randomized crossover trial. On four occasions, they consumed white bread (two times) and white bread with two different soymilks differing in protein and rice bran content...
April 4, 2018: Nutrients
https://www.readbyqxmd.com/read/29610581/bridging-glycated-hemoglobin-with-quality-of-life-and-health-state-a-randomized-case-control-study-among-type-2-diabetes-patients
#5
Syed Wasif Gillani, Irfan Altaf Ansari, Hisham A Zaghloul, Mohi Iqbal Mohammad Abdul, Syed Azhar Syed Sulaiman, Mirza R Baig
Background: The aim of this study was to explore the predictors of QOL and health state and examine the relationship with glycemic control among type 2 diabetes mellitus (T2DM) patients. Methods: A randomized cross-sectional case-control study was conducted among n = 600 T2DM patients of Malaysia. Study population was distributed into three groups as: controls: patients with HbA1c ≤ 7 (n = 199), cases arm 1: with HbA1c 7-7.9 (n = 204) and cases arm 2 (n = 197): with HbA1c ≥ 8 consecutively last 3 times...
2018: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29603657/changes-in-plasma-metabolite-concentrations-after-a-low-glycemic-index-diet-intervention
#6
Pablo Hernández-Alonso, Simona Giardina, Daniel Cañueto, Jordi Salas-Salvadó, Nicolau Cañellas, Mònica Bulló
SCOPE: To examine whether a low-glycemic index (LGI) diet improves a set of plasma metabolites related to different metabolic diseases and compared to a high-glycemic index (HGI) diet and a low-fat (LF) diet. METHODS AND RESULTS: We conducted a parallel, randomized trial with three intervention diets: a LGI diet, a HGI diet and a LF diet. A total of 122 adult overweight and obese subjects were enrolled in the study for 6 months. Blood samples were collected at baseline and at the end of the intervention...
March 30, 2018: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/29602622/the-application-of-simple-metrics-in-the-assessment-of-glycaemic-variability
#7
REVIEW
L Monnier, C Colette, D R Owens
The assessment of glycaemic variability (GV) remains a subject of debate with many indices proposed to represent either short- (acute glucose fluctuations) or long-term GV (variations of HbA1c ). For the assessment of short-term within-day GV, the coefficient of variation for glucose (%CV) defined as the standard deviation adjusted on the 24-h mean glucose concentration is easy to perform and with a threshold of 36%, recently adopted by the international consensus on use of continuous glucose monitoring, separating stable from labile glycaemic states...
March 6, 2018: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29602522/high-glycemic-index-metabolic-damage-a-pivotal-role-of-gip-and-glp-1
#8
REVIEW
Andreas F H Pfeiffer, Farnaz Keyhani-Nejad
When glucose-fructose dimers are supplied as the slowly digestible, completely absorbable, low glycemic index (GI) sugar isomaltulose, the detrimental effects of high GI sucrose are avoided. This difference requires the presence of intact glucose-induced insulinotropic peptide receptor (GIPR) and is mediated by the rapid uptake of glucose and the stimulation of GIP release from K cells in the upper small intestine. GIP promotes lipogenesis, fatty liver, insulin resistance, and postprandial inflammation, and reduces fat oxidation in skeletal muscle, partly by hypothalamic interference with energy partitioning and epigenetic programming...
March 27, 2018: Trends in Endocrinology and Metabolism: TEM
https://www.readbyqxmd.com/read/29596052/the-impact-of-mild-hypercholesterolemia-on-glycemic-and-hormonal-profiles-menstrual-characteristics-and-the-ovarian-morphology-of-women-with-polycystic-ovarian-syndrome
#9
Vasilios Pergialiotis, Eftihios Trakakis, Charalampos Chrelias, Nikolaos Papantoniou, Erifili Hatziagelaki
Background The severity of polycystic ovarian syndrome (PCOS) has been clearly associated with insulin resistance, obesity and metabolic syndrome. The purpose of the present cross-sectional study is to investigate whether mild hypercholesterolemia alters the biochemical and clinical profile of PCOS patients. Methods Our study is based on a prospectively collected population of women of reproductive age who were diagnosed with PCOS according to the definition of the Rotterdam European Society of Human Reproduction and Embryology/American Society for Reproductive Medicine (ASRM/ESHRE) criteria...
March 29, 2018: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/29588983/ketogenic-diet-for-treatment-of-intractable-epilepsy-in-adults-a-meta-analysis-of-observational-studies
#10
REVIEW
Hongyan Liu, Yi Yang, Yunbing Wang, Hong Tang, Fan Zhang, Yong Zhang, Yong Zhao
The ketogenic diet (KD) is an effective treatment for children with drug-resistant epilepsy and has been widely used in young children. Adult patients with intractable epilepsy would also benefit from this dietary treatment. However, only a few studies have been published, and the use of the KD in intractable epilepsy in adults has been limited. This meta-analysis summarized the findings of the relevant published studies to identify the efficacy of the KD for the treatment of intractable epilepsy in adults...
March 2018: Epilepsia Open
https://www.readbyqxmd.com/read/29581738/effect-of-probucol-on-hemodynamics-rheology-and-blood-lipid-of-diabetic-retinopathy
#11
Hong Liu, Mingming Cai
The effect of probucol in the treatment of diabetic retinopathy was investigated to analyze its impact on its hemodynamics, rheology and blood lipid. A total of 80 patients with diabetic retinopathy who were treated in the Ninth People's Hospital of Chongqing (Chongqing, China) from January 2015 to August 2016 were selected and divided into two groups by random number table, with 40 patients in each group. Control group was treated by conventional and intensive glycemic control and antihypertensive therapy, while observation group was orally administered with 0...
April 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29562613/effects-of-low-versus-moderate-glycemic-index-diets-on-aerobic-capacity-in-endurance-runners-three-week-randomized-controlled-crossover-trial
#12
Krzysztof Durkalec-Michalski, Emilia E Zawieja, Bogna E Zawieja, Dominika Jurkowska, Maciej S Buchowski, Jan Jeszka
The glycemic index (GI) of ingested carbohydrates may influence substrate oxidation during exercise and athletic performance. Therefore, the aim of this study was to assess the effect of low- and moderate-GI three-week diets on aerobic capacity and endurance performance in runners. We conducted a randomized crossover feeding study of matched diets differing only in GI (low vs. moderate) in 21 endurance-trained runners. Each participant consumed both, low- (LGI) and moderate-GI (MGI) high-carbohydrate (~60%) and nutrient-balanced diets for three weeks each...
March 17, 2018: Nutrients
https://www.readbyqxmd.com/read/29558830/naturopathic-oncology-care-for-thoracic-cancers-a-practice-survey
#13
Dugald Seely, Julie K Ennis, Ellen McDonell, Linlu Zhao
BACKGROUND AND OBJECTIVES: There is a lack of information on therapies recommended by naturopathic doctors (NDs) for lung and gastroesophageal cancer care. Study objectives were to: (1) identify the most common interventions considered for use by NDs; (2) identify interventions NDs recommend to support key therapeutic goals; and (3) identify potential contraindications between integrative and conventional therapies. METHODS: Oncology Association of Naturopathic Physicians (OncANP) members (n = 351) were invited to complete an electronic survey...
March 1, 2018: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/29546070/d-tagatose-is-a-promising-sweetener-to-control-glycaemia-a-new-functional-food
#14
REVIEW
Marion Guerrero-Wyss, Samuel Durán Agüero, Lisse Angarita Dávila
The objective of the current research was to review and update evidence on the dietary effect of the consumption of tagatose in type 2 diabetes, as well as to elucidate the current approach that exists on its production and biotechnological utility in functional food for diabetics. Articles published before July 1, 2017, were included in the databases PubMed, EBSCO, Google Scholar, and Scielo, including the terms "Tagatose", "Sweeteners", "Diabetes Mellitus type 2", "Sweeteners", "D-Tag"...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29535944/lipid-profile-in-relation-to-glycemic-control-in-type-1-diabetes-children-and-adolescents-in-bangladesh
#15
Bedowra Zabeen, Ana Margarida Balsa, Nasreen Islam, Mukta Parveen, Jebun Nahar, Kishwar Azad
Introduction: Dyslipidemia and hyperglycemia are metabolic abnormalities commonly found in young patients with Type 1 diabetes mellitus (T1DM) and both increase the risk of cardiovascular disease. Methods: This cross-sectional study was aimed to evaluate the pattern of dyslipidemia and its relationship with other risk factors in children and adolescents with T1DM. A total of 576 T1DM patients aged 10-18 years who attended Changing Diabetes in Children, a pediatric diabetes clinic in Bangladesh Institute of Research and Rehabilitation for Diabetes, Endocrine and Metabolic Disorders over 1 year period from July 2015 to June 2016 were included in this study...
January 2018: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29528768/effect-of-low-energy-dense-diet-rich-in-multiple-functional-foods-on-weight-loss-maintenance-inflammation-and-cardiovascular-risk-factors-a-randomized-controlled-trial
#16
Vajihe Izadi, Fahimeh Haghighatdoost, Parisa Moosavian, Leila Azadbakht
BACKGROUND: There are no investigations regarding the effects of consuming low-energy-dense diets rich in multiple functional foods on weight-loss maintenance, inflammatory markers, and cardiovascular disease (CVD) risk factors simultaneously. METHOD: This randomized controlled trial design was conducted on 90 men and women who were under a previous weight loss diet. Three months of intervention with recruitment at Allzahra Hospital, Isfahan, Iran, was done. Intervention was conducted following achieving 7-11 kg weight loss...
March 12, 2018: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/29504728/the-role-of-lifestyle-changes-in-the-treatment-of-polycystic-ovary-syndrome
#17
Magdalena Smyka, Barbara Grzechocinska, Miroslaw Wielgos
Polycystic ovary syndrome is one of the most common endocrinopathy of the reproductive age. Heterogenity of its clinical symptoms is related to the presence of a number of phenotypes of this disfunction, hence the necessity for individualized treatment is needed. A change of a lifestyle, well-balanced diet and physical activity are the most effective medical way contributing to the improvement of carbohydrate metabolism parameters and weight reduction which reactivates regular ovulation and facilitates getting pregnant...
February 6, 2018: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29502926/phenylketonuric-diet-negatively-impacts-on-butyrate-production
#18
E Verduci, F Moretti, G Bassanini, G Banderali, V Rovelli, M C Casiraghi, G Morace, F Borgo, E Borghi
BACKGROUND AND AIMS: Phenylalanine (Phe) restricted diet, combined with Phe-free l-amino acid supplementation, is the mainstay of treatment for phenylketonuria (PKU). Being the diet a key factor modulating gut microbiota composition, the aim of the present paper was to compare dietary intakes, gut microbiota biodiversity and short chain fatty acids (SCFAs) production in children with PKU, on low-Phe diet, and in children with mild hyperphenylalaninemia (MHP), on unrestricted diet. METHODS AND RESULTS: We enrolled 21 PKU and 21 MHP children matched for gender, age and body mass index z-score...
January 31, 2018: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29502278/the-effects-of-laparoscopic-sleeve-gastrectomy-with-duodenojejunal-bypass-on-japanese-patients-with-bmi-35-kg-m-2-on-type-2-diabetes-mellitus-and-the-prediction-of-successful-glycemic-control
#19
Yosuke Seki, Kazunori Kasama, Kazuki Yasuda, Renzo Yokoyama, Jose Paolo Porciuncula, Yoshimochi Kurokawa
BACKGROUND: Laparoscopic sleeve gastrectomy with duodenojejunal bypass (LSG-DJB) is a combination of sleeve gastrectomy and proximal intestinal bypass through duodenal exclusion. This technique has shown excellent weight loss and anti-diabetic effects in severely obese patients. In this retrospective study, we examined the clinical effects of LSG-DJB on mildly obese patients (body mass index (BMI) < 35 kg/m2 ) with type 2 diabetes mellitus (T2DM) and analyzed factors contributing to the successful postoperative glycemic control...
March 3, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29463026/the-nile-rat-arvicanthis-niloticus-as-a-superior-carbohydrate-sensitive-model-for-type-2-diabetes-mellitus-t2dm
#20
REVIEW
Avinaash Subramaniam, Michelle Landstrom, Alice Luu, K C Hayes
Type II diabetes mellitus (T2DM) is a multifactorial disease involving complex genetic and environmental interactions. No single animal model has so far mirrored all the characteristics or complications of diabetes in humans. Since this disease represents a chronic nutritional insult based on a diet bearing a high glycemic load, the ideal model should recapitulate the underlying dietary issues. Most rodent models have three shortcomings: (1) they are genetically or chemically modified to produce diabetes; (2) unlike humans, most require high-fat feeding; (3) and they take too long to develop diabetes...
February 18, 2018: Nutrients
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