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https://www.readbyqxmd.com/read/28507727/correlation-between-hemoglobin-a1c-and-serum-lipid-profile-in-afghani-patients-with-type-2-diabetes-hemoglobin-a1c-prognosticates-dyslipidemia
#1
Arshad Hussain, Iftikhar Ali, Muhammad Ijaz, Afaq Rahim
BACKGROUND: Patients with type 2 diabetes (T2DM) have an increased prevalence of dyslipidemia, which contributes to their high risk of cardiovascular diseases (CVDs). This study is an attempt to determine the correlation between hemoglobin A1c (HbA1c) and serum lipid profile and to evaluate the importance of HbA1c as an indicator of dyslipidemia in Afghani patients with T2DM. METHODS: A total of 401 Afghani patients with T2DM (men, 175; women, 226; mean age, 51...
April 2017: Therapeutic Advances in Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28502503/the-effects-of-vitamin-d-and-omega-3-fatty-acid-co-supplementation-on-glycemic-control-and-lipid-concentrations-in-patients-with-gestational-diabetes
#2
Mehri Jamilian, Mansooreh Samimi, Faraneh Afshar Ebrahimi, Teibeh Hashemi, Mohsen Taghizadeh, Maryamalsadat Razavi, Marzieh Sanami, Zatollah Asemi
OBJECTIVE: This study was performed to evaluate the effects of vitamin D and omega-3 fatty acids co-supplementation on glucose metabolism and lipid concentrations in gestational diabetes (GDM) patients. METHODS: This randomized double-blind placebo-controlled clinical trial was done among 140 GDM patients. Participants were randomly divided into 4 groups to receive: (1) 1000 mg omega-3 fatty acids containing 360 mg eicosapentaenoic acid and 240 mg docosahexaenoic acid (DHA) twice a day + vitamin D placebo (n = 35); (2) 50,000 IU vitamin D every 2 weeks + omega-3 fatty acids placebo (n = 35); (3) 50,000 IU vitamin D every 2 weeks + 1000 mg omega-3 fatty acids twice a day (n = 35), and (4) vitamin D placebo + omega-3 fatty acids placebo (n = 35) for 6 weeks...
March 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28493502/fasiglifam-for-glycemic-control-in-patients-with-type-2-diabetes-a-phase-3-placebo-controlled-study
#3
John Marcinak, Charles Cao, Douglas Lee, Zhan Ye
AIM: To investigate the effect of fasiglifam on glycemic control in patients with type 2 diabetes mellitus (T2DM). METHODS: In total, 421 patients with T2DM and glycosylated hemoglobin (HbA1c) ≥7.0% but ≤10.5% who had been treated with diet and exercise only for ≥12 weeks prior to screening were randomized to receive fasiglifam 25 mg or 50 mg or placebo. The primary efficacy endpoint was change from baseline in HbA1c at week 24. RESULTS: Patient mean age was 53...
May 11, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28490113/mitigating-the-in-vitro-enzymatic-digestibility-of-noodles-by-aqueous-extracts-of-malay-cherry-leaves
#4
Yan Zhang, Xiaonan Sui, Dejian Huang
Aqueous extracts of Malay cherry leaves was incorporated into wheat, rice, tapioca, and potato flours with the purpose to formulate noodles with slow digestibility. In vitro digestion studies of these noodle prototypes were carried out to evaluate their digestibility under simulated gastrointestinal conditions. Upon incorporation of 2-8% of aqueous extracts, all four different types of noodles exhibited dose dependency with varying degree of digestibility. The greatest reduction in digestibility was observed in 8% tapioca noodles (69...
October 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28472140/validation-of-a-diabetes-numeracy-test-in-arabic
#5
Hussah Alghodaier, Hoda Jradi, Najwa Samantha Mohammad, Amen Bawazir
BACKGROUND: The prevalence of diabetes Mellitus in Saudi Arabia is 24%, ranking it among the top ten Worldwide. Diabetes education focuses on self-management and relies on numeracy skills. Poor numeracy may go unrecognized and it is important to have an assessment tool in Arabic to measure such a skill in diabetes care. OBJECTIVES: To validate a 15-item Diabetes Numeracy Test (DNT-15) in the Arabic Language as a tool to assess the numeracy skills of patients with diabetes and to test its properties among Saudi patients with diabetes...
2017: PloS One
https://www.readbyqxmd.com/read/28453522/potential-biological-pathways-linking-type-d-personality-and-poor-health-a-cross-sectional-investigation
#6
Vera K Jandackova, Julian Koenig, Marc N Jarczok, Joachim E Fischer, Julian F Thayer
BACKGROUND: Type-D personality, defined as a combination of high negative affect and high social isolation, has been associated with poor health outcomes. However, pathways underlying this association are largely unknown. We investigated the relationship between Type-D personality and several biological and behavioral pathways including the autonomic nervous system, the immune system, glucose regulation and sleep in a large, apparently healthy sample. METHODS: Data from a total of 646 respondents (age 41...
2017: PloS One
https://www.readbyqxmd.com/read/28448779/effect-of-a-pharmacist-led-program-on-improving-outcomes-in-patients-with-type-2-diabetes-mellitus-from-northern-cyprus-a-randomized-controlled-trial
#7
Eylem Ilktac Korcegez, Mesut Sancar, Kutay Demirkan
BACKGROUND: The management of type 2 diabetes mellitus is complex, requiring continuous medical care by health care professionals and considerable self-care efforts by patients. Pharmacist-led care programs have been shown to help patients with diabetes succeed in achieving treatment goals and improving outcomes. Pharmacist-led care is a new health care concept in Northern Cyprus. OBJECTIVE: To evaluate the effect of a pharmacist-led care program on glycemic control, determined by hemoglobin A1c (A1c), and secondarily on blood pressure, lipid profile, body mass index (BMI), waist circumference, medication adherence, and self-care activities, for patients with type 2 diabetes over a 12-month period...
May 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28446494/effects-of-the-mean-amplitude-of-glycemic-excursions-and-vascular-endothelial-dysfunction-on-cardiovascular-events-in-nondiabetic-patients-with-coronary-artery-disease
#8
Tomonori Akasaka, Daisuke Sueta, Noriaki Tabata, Seiji Takashio, Eiichiro Yamamoto, Yasuhiro Izumiya, Kenichi Tsujita, Sunao Kojima, Koichi Kaikita, Kunihiko Matsui, Seiji Hokimoto
BACKGROUND: Mean amplitude of glycemic excursion (MAGE) is commonly used to gauge the degree of glucose level fluctuations. MAGE plays a significant role in vascular endothelial dysfunction and cardiovascular events in patients with diabetes mellitus (DM), but its significance is not clear in non-DM patients. Thus, we examined the impact of MAGE and vascular endothelial dysfunction on clinical outcomes in non-DM patients with coronary artery disease. METHODS AND RESULTS: We followed non-DM patients (n=65) for 12 months who underwent percutaneous coronary intervention and assessed the relationship among MAGE, reactive hyperemia index (RHI) measured by reactive hyperemia peripheral arterial tonometry as endothelial function, and cardiovascular events...
April 26, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28445783/jump-starting-shared-medical-appointments-for-diabetes-with-weight-management-rationale-and-design-of-a-randomized-controlled-trial
#9
Matthew J Crowley, David Edelman, Corrine I Voils, Matthew L Maciejewski, Cynthia J Coffman, Amy S Jeffreys, Marsha J Turner, Leslie A Gaillard, Teresa A Hinton, Elizabeth Strawbridge, Jennifer Zervakis, Anna Beth Barton, William S Yancy
BACKGROUND: Rates of glycemic control remain suboptimal nationwide. Medication intensification for diabetes can have undesirable side effects (weight gain, hypoglycemia), which offset the benefits of glycemic control. A Shared Medical Appointment (SMA) intervention for diabetes that emphasizes weight management could improve glycemic outcomes and reduce weight while simultaneously lowering diabetes medication needs, resulting in less hypoglycemia and better quality of life. We describe the rationale and design for a study evaluating a novel SMA intervention for diabetes that primarily emphasizes low-carbohydrate diet-focused weight management...
April 23, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28431772/low-glycemic-index-treatment-in-patients-with-drug-resistant-epilepsy
#10
Se Hee Kim, Hoon-Chul Kang, Eun Joo Lee, Joon Soo Lee, Heung Dong Kim
OBJECTIVE: Low glycemic index treatment (LGIT) is a newly developed dietary therapeutic option for epilepsy that is less restrictive than the ketogenic diet (KD). Our objective was to determine the efficacy and tolerability of LGIT. METHODS: From March 2014 to February 2015, 36 patients received LGIT at Severance Children's Hospital. One-year seizure outcomes and side effects were evaluated. RESULTS: A total of 36 patients were assessed. Fourteen were female...
April 18, 2017: Brain & Development
https://www.readbyqxmd.com/read/28417910/effects-of-three-commercially-available-sports-drinks-on-substrate-metabolism-and-subsequent-endurance-performance-in-a-postprandial-state
#11
Lu Qin, Qi-Rong Wang, Zi-Long Fang, Ting Wang, Ai-Qi Yu, Yu-Jie Zhou, Yi Zheng, Mu-Qing Yi
Purpose: To examine the effects of commercially available sports beverages with various components on substrate metabolism and subsequent performance. Methods: Two studies were conducted in a double-blinded, counterbalanced manner. Study I was designed to determine the glycemic index, while study II determined the utilization of substrates and subsequent exercise performance. Ten healthy male participants (age 21.70 ± 2.41 years, height 176.60 ± 5.23 cm, weight 66.58 ± 5.38 kg, V̇O2max 48.1 ± 8.4 mL/kg/min) participated in both study I and study II...
April 12, 2017: Nutrients
https://www.readbyqxmd.com/read/28416531/treatment-deintensification-is-uncommon-in-adults-with-type-2-diabetes-mellitus-a-retrospective-cohort-study
#12
Finlay A McAlister, Erik Youngson, Dean T Eurich
BACKGROUND: Whether treatment deintensification in Americans with diabetes mellitus varies by glycemic control, health status, and calendar year (before/after February 2008 when safety concerns about intensive glucose control were reported in the ACCORD trial [Action to Control Cardiovascular Risk in Diabetes]) is unclear. METHODS AND RESULTS: We defined deintensification as discontinuation or dosage decrease of at least 1 glycemic medication without addition of, or uptitration of, another agent in the 120 days after the index glycosylated hemoglobin (HbA1C) measurement...
April 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28416368/nutritional-management-in-women-with-polycystic-ovary-syndrome-a-review-study
#13
REVIEW
Zeinab Faghfoori, Siavash Fazelian, Mahdi Shadnoush, Reza Goodarzi
Polycystic ovary syndrome (PCOS) is endocrine disorder in women of reproductive age, which leads to reproductive, hormonal and metabolic abnormalities. Due to the presence of insulin resistance, PCOS increases the risk of chronic diseases like type 2 diabetes, hypertension, lipid disorders, cardiovascular diseases and malignancies such as breast and endometrial cancer. The actual cause of this syndrome is unknown but environmental factors such as dietary habits play an important role in prevention and treatment and lifestyle modifications are the most important therapeutic strategies in these patients...
April 5, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28406437/low-glycemic-index-prototype-isomaltulose-update-of-clinical-trials
#14
REVIEW
Constanze Christin Maresch, Sebastian Friedrich Petry, Stephan Theis, Anja Bosy-Westphal, Thomas Linn
Low glycemic index diets are supposed to achieve a more beneficial effect on blood glucose control in people with diabetes mellitus and may also provide metabolic benefits for the general population. A prototype of a low-glycemic index carbohydrate is the natural occurring disaccharide isomaltulose that can be commercially produced from sucrose (beet sugar) to industrial scale. It is currently used in various food and drink applications as well as special and clinical nutrition feeds and formula diet as a food ingredient and alternative sugar...
April 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28405345/lower-glycemic-load-meals-reduce-diurnal-glycemic-oscillations-in-women-with-risk-factors-for-gestational-diabetes
#15
Nathalie V Kizirian, Janina Goletzke, Shannon Brodie, Fiona S Atkinson, Tania P Markovic, Glynis P Ross, Anette Buyken, Jennie P Brand-Miller
OBJECTIVE: Maternal glycemia plays a key role in fetal growth. We hypothesized that lower glycemic load (GL) meals (lower glycemic index, modestly lower carbohydrate) would substantially reduce day-long glucose variability in women at risk of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS: A crossover study of 17 women (mean±SD age 34.8±4 years; gestational weeks 29.3±1.3; body mass index 23.8±4.7 kg/m(2)) who consumed a low GL or a high GL diet in random order, 1-day each, over 2 consecutive days...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28405340/association-of-physiological-and-psychological-health-outcomes-with-physical-activity-and-sedentary-behavior-in-adults-with-type-2-diabetes
#16
Jeanette M Garcia, Daniel Cox, David J Rice
PURPOSE: To examine the association between change in moderate-to-vigorous physical activity (MVPA) and sedentary behavior (SB) over a 6-month period with physiological and psychological factors in adults with type 2 diabetes (T2D). METHODS: Participants included 26 middle-aged (mean age=56.1±10.8 years; 42% women), overweight/obese (mean body mass index (BMI) =37.22±8.78 kg/m(2)) adults who had been diagnosed with T2D within the past 5 years (mean HbA1c=7...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28404579/glycemic-index-glycemic-load-and-blood-pressure-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#17
Charlotte El Evans, Darren C Greenwood, Diane E Threapleton, Chris P Gale, Christine L Cleghorn, Victoria J Burley
Background: High blood pressure is a strong risk factor for cardiovascular disease.Objective: The aim of this study was to determine the associations of dietary glycemic index (GI) and glycemic load (GL) with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in healthy individuals.Design: A systematic review and meta-analysis of randomized controlled trials (RCTs) was carried out. Databases were searched for eligible RCTs in 2 phases. MEDLINE, Embase, CAB Abstracts, BIOSIS, ISI Web of Science, and the Cochrane Library were searched from January 1990 to December 2009...
April 12, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28399076/effects-of-a-10-day-intensive-health-promotion-program-combining-diet-and-physical-activity-on-body-composition-physical-fitness-and-blood-factors-of-young-adults-a-randomized-pilot-study
#18
Kyoung Soon Lee, Jae Koo Lee, Young Ran Yeun
BACKGROUND A lifestyle characterized by poor eating habits and physical inactivity is a risk factor for multiple lifestyle diseases in young adults. This study assessed the effects of implementing an intensive 10-day health promotion program combining diet and physical activities on body composition, physical fitness, and biochemical parameters of young adults. MATERIAL AND METHODS In this randomized pilot study, 30 female undergraduate students were randomly allocated to an intervention and a control group...
April 11, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28392166/legume-consumption-is-inversely-associated-with-type-2-diabetes-incidence-in-adults-a-prospective-assessment-from-the-predimed-study
#19
Nerea Becerra-Tomás, Andrés Díaz-López, Núria Rosique-Esteban, Emilio Ros, Pilar Buil-Cosiales, Dolores Corella, Ramon Estruch, Montserrat Fitó, Lluís Serra-Majem, Fernando Arós, Rosa Maria Lamuela-Raventós, Miquel Fiol, José Manuel Santos-Lozano, Javier Díez-Espino, Olga Portoles, Jordi Salas-Salvadó
BACKGROUND & AIMS: Legumes, a low-energy, nutrient-dense and low glycemic index food, have shown beneficial effects on glycemic control and adiposity. As such, legumes are widely recommended in diabetic diets, even though there is little evidence that their consumption protects against type 2 diabetes. Therefore the aim of the present study was to examine the associations between consumption of total legumes and specific subtypes, and type 2 diabetes risk. We also investigated the effect of theoretically substituting legumes for other protein- or carbohydrate-rich foods...
March 24, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28392017/medical-nutrition-therapy-for-post-bariatric-hypoglycemia-practical-insights
#20
Emmy Suhl, Sue-Ellen Anderson-Haynes, Christopher Mulla, Mary-Elizabeth Patti
Hypoglycemia is increasingly recognized as a complication of bariatric surgery. Although medications are often required, medical nutrition therapy remains the key cornerstone for successful prevention of hypoglycemia in patients with post-bariatric hypoglycemia (PBH). We provide suggested approaches to the dietary management of PBH, incorporating data from both the medical literature and extensive clinical experience in an academic referral center for PBH. The overall goal of medical nutrition therapy for PBH is to reduce postprandial surges in glucose, which often trigger surges in insulin secretion and promote subsequent hypoglycemia...
January 16, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
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