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https://www.readbyqxmd.com/read/29026804/the-effect-of-cardamom-supplementation-on-serum-lipids-glycemic-indices-and-blood-pressure-in-overweight-and-obese-pre-diabetic-women-a-randomized-controlled-trial
#1
Yaghooblou Fatemeh, Fereydoun Siassi, Abbas Rahimi, Fariba Koohdani, Farideh Doostan, Mostafa Qorbani, Gity Sotoudeh
BACKGROUND: Spice consumption helps the treatment of diseases due to their antioxidant and anti-inflammatory contents. Cardamom is one of this spices; therefore, this study is designed to determine the effect of cardamom supplementation on serum lipids, glycemic indices, and blood pressure in pre-diabetic women. METHODS: Eighty overweight or obese pre-diabetic women were randomly allocated to two groups. The intervention group received 3 g of green cardamom and the placebo group received 3 g of rusk powder for 2 months...
2017: Journal of Diabetes and Metabolic Disorders
https://www.readbyqxmd.com/read/29024341/modulation-of-human-subcutaneous-adipose-tissue-microrna-profile-associated-with-changes-in-adiposity-related-parameters
#2
Simona Giardina, Pablo Hernández-Alonso, Jordi Salas-Salvadó, Antoni Rabassa-Soler, Mònica Bulló
SCOPE: To analyze the effect of three calorie-restricted diets with different amount and quality of carbohydrates on subcutaneous adipose tissue (SAT) miRNA profile. METHODS AND RESULTS: 6-month, parallel, randomized trial conducted on overweight and obese subjects randomized to: 1) low glycemic index diet (LGI), 2) high glycemic index diet (HGI), and 3) low-fat (LF). The genome-wide SAT miRNA profile was assessed in 8 randomly selected participants and the most relevant changing miRNAs (n = 13) were validated in 48 subjects...
October 10, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/29021286/pomegranate-juice-but-not-an-extract-confers-a-lower-glycemic-response-on-a-high-glycemic-index-food-randomized-crossover-controlled-trials-in-healthy-subjects
#3
Asimina Kerimi, Hilda Nyambe-Silavwe, Julia S Gauer, Francisco A Tomás-Barberán, Gary Williamson
Background: Low-glycemic index diets have demonstrated health benefits associated with a reduced risk of developing type 2 diabetes.Objectives: We tested whether pomegranate polyphenols could lower the glycemic response of a high-glycemic index food when consumed together and the mechanism by which this might occur.Design: We compared the acute effect of a pomegranate juice and a polyphenol-rich extract from pomegranate (supplement) on the bread-derived postprandial blood glucose concentration in 2 randomized, crossover, controlled studies (double-blinded for the supplements), each on 16 healthy volunteers...
October 11, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29021277/cardiometabolic-risk-variables-in-preadolescent-children-a-factor-analysis
#4
Lee Stoner, Mark Weatherall, Paula Skidmore, Nicholas Castro, Sally Lark, James Faulkner, Michelle A Williams
BACKGROUND: Atherosclerosis begins during preadolescence and is occurring at an accelerated rate. This acceleration has been linked to poor lifestyle behaviors and subsequent cardiometabolic complications. Although the clustering of cardiometabolic risk factors has been recognized for over 2 decades, previous studies in children have predominantly examined the relationships between atherosclerosis and individual cardiometabolic risk factors or have grouped together preadolescent and adolescent children...
October 11, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29018489/effects-of-resveratrol-on-glucose-control-and-insulin-sensitivity-in-subjects-with-type-2-diabetes-systematic-review-and-meta-analysis
#5
REVIEW
Xiangyun Zhu, Chunhua Wu, Shanhu Qiu, Xuelu Yuan, Ling Li
Although the regular consumption of resveratrol has been known to improve glucose homeostasis and reverse insulin resistance in type 2 diabetes mellitus (T2DM), the reported results are inconsistent. Thus, we aimed to assess the effects of resveratrol on glycemic control and insulin sensitivity among patients with T2DM. We searched for relevant articles published until June 2017 on PubMed-Medline, Embase, Cochrane Library, and Web of Science. Randomized controlled trials in T2DM patients administered with resveratrol as intervention were included...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/29017497/the-effects-of-vildagliptin-compared-with-metformin-on-vascular-endothelial-function-and-metabolic-parameters-a-randomized-controlled-trial-sapporo-athero-incretin-study-3
#6
Naoyuki Kitao, Hideaki Miyoshi, Tomoo Furumoto, Kota Ono, Hiroshi Nomoto, Aika Miya, Chiho Yamamoto, Atsushi Inoue, Kenichi Tsuchida, Naoki Manda, Yoshio Kurihara, Shin Aoki, Akinobu Nakamura, Tatsuya Atsumi
BACKGROUND: Dipeptidyl peptidase-4 (DPP-4) inhibitors may have protective effects in the early stage of atherosclerosis in patients with type 2 diabetes, although similar effects in advanced atherosclerosis were not shown in recent randomized placebo-controlled studies. Therefore, we investigated the efficacy of DPP-4 inhibitor on endothelial function and glycemic metabolism compared with high-dose metformin. METHODS: In this multicenter, open-labeled, prospective, randomized, parallel-group comparison study, patients with type 2 diabetes treated with low-dose metformin (500-750 mg/day) were enrolled and randomly assigned to a vildagliptin, a DPP-4 inhibitor, add-on group (Vilda) or a double dose of metformin group (high Met) for 12 weeks...
October 10, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/28991272/%C3%A3-ndice-gluc%C3%A3-mico-y-carga-gluc%C3%A3-mica-en-el-fruto-de-la-especie-vegetal-opuntia-ficus-indica
#7
María de Jesús Ibarra-Salas, Hilda Irene Novelo-Huerta, Marcela Alejandra De León-Salas, Mayra Elisa Sánchez-Murillo, María Del Carmen Mata-Obregón, Aurora de Jesús Garza-Juárez
other: Existe evidencia que apoya la utilidad clínica de que el índice glucémico (IG) y la carga glucémica (CG) podrían ser importantes en la prevención de enfermedades crónicas. Objetivo: Determinar el IG y la CG del fruto de Opuntia ficus-indica (tuna). Metodología: Se realizó un estudio analítico, transversal, con 25 voluntarios sanos con valores normales de índice de masa corporal, glucosa, hemoglobina glucosilada, colesterol y triglicéridos séricos, que mediante consentimiento informado aceptaron participar...
2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28985731/screening-for-celiac-disease-in-poorly-controlled-type-2-diabetes-mellitus-worth-it-or-not
#8
Muhammed Kizilgul, Ozgur Ozcelik, Selvihan Beysel, Hakan Akinci, Seyfullah Kan, Bekir Ucan, Mahmut Apaydin, Erman Cakal
BACKGROUND: Recent studies have demonstrated that immune factors might have a role in the pathophysiology of insulin resistance and type 2 diabetes mellitus (T2DM). Inappropriate glycemic control in patients with T2DM is an important risk factor for the occurrence of diabetes complications. The prevalence of celiac disease (CD) is high in type 1 diabetes mellitus however, there are scarce data about its prevalence in T2DM. Our aim was to investigate the prevalence of celiac disease among insulin-using type 2 diabetes patients with inappropriate glycemic control...
October 6, 2017: BMC Endocrine Disorders
https://www.readbyqxmd.com/read/28983746/performance-of-granular-starch-with-controlled-pore-size-during-hydrolysis-with-digestive-enzymes
#9
Yaiza Benavent-Gil, Cristina M Rosell
Studies on porous starch have been directed to explore different industrial applications as bio-adsorbents of a variety of compounds. However, the analysis of starch digestibility is essential for food application. The objective of this study was to determine the impact of porous structure on in vitro starch digestibility. Porous starches were obtained using a range of concentrations of amyloglucosidase (AMG), α-amylase (AM), cyclodextrin-glycosyltransferase (CGTase) or branching enzyme (BE). Porous starches exhibited major content of digestible starch (DS) that increased with the intensity of the enzymatic treatment, and very low amount of resistant starch (RS)...
October 5, 2017: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/28978672/magnesium-intake-quality-of-carbohydrates-and-risk-of-type-2-diabetes-results-from-three-u-s-cohorts
#10
Adela Hruby, Marta Guasch-Ferré, Shilpa N Bhupathiraju, JoAnn E Manson, Walter C Willett, Nicola M McKeown, Frank B Hu
OBJECTIVE: Magnesium intake is inversely associated with risk of type 2 diabetes in many observational studies, but few have assessed this association in the context of the carbohydrate quality of the diet. We hypothesized that higher magnesium intake is associated with lower risk of type 2 diabetes, especially in the context of a poor-carbohydrate-quality diet characterized by low cereal fiber or high glycemic index (GI) or glycemic load (GL). RESEARCH DESIGN AND METHODS: In the Nurses' Health Study (NHS; 1984-2012, n = 69,176), NHS2 (1991-2013, n = 91,471), and the Health Professionals' Follow-Up Study (1986-2012, n = 42,096), dietary intake was assessed from food frequency questionnaires every 4 years...
October 4, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28976933/glycemic-response-to-black-beans-and-chickpeas-as-part-of-a-rice-meal-a-randomized-cross-over-trial
#11
Donna M Winham, Andrea M Hutchins, Sharon V Thompson
Legumes, such as black beans (Phaseolus vulgaris L.) and chickpeas (Cicer arietinum L.), have a low glycemic index, and may reduce the glycemic load of meals in which they are included. Although the low glycemic response of beans consumed alone has been documented, few studies have examined the glycemic response to traditional food combinations such as black beans and rice or chickpeas and rice. This randomized cross-over study examined the glycemic and insulinemic impact of 50 grams of available carbohydrate from three test meals: plain white rice (control), black beans with rice, and chickpeas with rice among healthy adult women (n = 12, 18-65 years)...
October 4, 2017: Nutrients
https://www.readbyqxmd.com/read/28972240/fruit-form-influences-postprandial-glycemic-response-in-elderly-and-young-adults
#12
S L Tey, D E M Lee, C J Henry
OBJECTIVES: This study compared the effects of consuming different forms (bite size, puree) and two fruit types (guava, papaya) on glycemic response (GR) in elderly and young adults. DESIGN: This study was conducted using a randomized, crossover design. PARTICIPANTS: Nineteen healthy participants (9 elderly, 10 young adults) were recruited from the general public in Singapore. INTERVENTION: Participants consumed glucose (reference food) on three occasions and test fruits (guava bites, guava puree, papaya bites, and papaya puree) on one occasion each...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28959813/investigating-the-relationship-between-lentil-carbohydrate-fractions-and-in-vivo-postprandial-blood-glucose-response-by-use-of-the-natural-variation-in-starch-fractions-among-20-lentil-varieties
#13
D Dan Ramdath, Qiang Liu, Elizabeth Donner, Aileen Hawke, Danusha Kalinga, Jordan Winberg, Thomas M S Wolever
Consumption of pulses is associated with many health benefits by mechanisms that are not fully understood. This study sought to identify the starch component(s) in cooked lentils responsible for lowering postprandial glycemic response (PPGR). Rapidly digestible (RDS), slowly digestible (SDS) and resistant starch (RS) content of 20 varieties of cooked lentil were determined by in vitro methods and 8 varieties, representing a linear range of SDS, were chosen for a human trial with 10 participants to determine PPGR and glycemic index (GI)...
September 29, 2017: Food & Function
https://www.readbyqxmd.com/read/28958804/effect-of-a-low-glycemic-index-diet-versus-a-high-cereal-fiber-diet-on-markers-of-subclinical-cardiac-injury-in-healthy-individuals-with-type-2-diabetes-mellitus-an-exploratory-analysis-of-a-randomized-dietary-trial
#14
Vanessa Ha, Effie Viguiliouk, Cyril W C Kendall, Bashyam Balachandran, David J A Jenkins, Peter A Kavsak, John L Sievenpiper
BACKGROUND: Markers of subclinical cardiac injury are elevated in individuals with type 2 diabetes mellitus (T2DM) compared to healthy individuals. Low glycemic index (LGI) diets may improve both diabetes and cardiovascular risk but their effects on cardiac injury and fibrosis have not been previously studied. To test the effect of a LGI diet on markers of subclinical cardiac injury and fibrosis, we assessed the effect of a LGI compared with a high-cereal fiber diet on high-sensitivity cardiac troponin I (hs-cTnI) and galectin-3 in otherwise healthy individuals with T2DM in an exploratory analysis of a completed randomized trial...
September 25, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28956658/short-term-supplementation-of-a-moderate-carbohydrate-diet-with-psyllium-reduces-fasting-plasma-insulin-and-tumor-necrosis-factor-%C3%AE-in-patients-with-type-2-diabetes-mellitus
#15
Mahdieh Kamalpour, Hamid Ghalandari, Javad Nasrollahzadeh
The purpose of this study was to compare effects of a moderate carbohydrate diet supplemented with psyllium with those of a lower carbohydrate diet supplemented with placebo powder on glycemic control in patients with type 2 diabetes (T2D). In an open randomized controlled trial, 37 patients with T2D with body mass index (BMI) 25-35 kg/m2 received either a low-energy, moderate carbohydrate diet plus 7 grams of psyllium powder (MoCyllium group) or a low-energy, lower carbohydrate diet plus placebo powder (LoCarb group) for 2 weeks...
September 28, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28954707/a-systematic-review-on-the-relations-between-pasta-consumption-and-cardio-metabolic-risk-factors
#16
REVIEW
M Huang, J Li, M-A Ha, G Riccardi, S Liu
AIMS: The traditional Italian dish pasta is a major food source of starch with low glycemic index (GI) and an important low-GI component of the Mediterranean diet. This systematic review aimed at assessing comprehensively and in-depth the potential benefit of pasta on cardio-metabolic disease risk factors. DATA SYNTHESIS: Following a standard protocol, we conducted a systematic literature search of PubMed, CINAHL, and Cochrane Central Register of Controlled Trials for prospective cohort studies and randomized controlled dietary intervention trials that examined pasta and pasta-related fiber and grain intake in relation to cardio-metabolic risk factors of interest...
July 18, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/28942668/recent-exposure-to-hypoglycemia-increases-glucose-variability-following-a-hyper-hypoglycemic-metabolic-challenge-in-t1d
#17
Chiara Fabris, Leon S Farhy, Stacey M Anderson, Ralf M Nass, Boris P Kovatchev, Marc D Breton
AIMS: In type 1 diabetes (T1D), repeated hypoglycemic episodes may reduce hormonal defenses and increase the risk for severe hypoglycemia. In this work, we investigate the effect of a structured hyper/hypoglycemic metabolic challenge on the postintervention glucose variability in T1D subjects studied at home. METHODS: Thirty T1D subjects using insulin pump were monitored with blood glucose meters (SMBG) during a 1-month observation period. After 2 weeks of monitoring, participants were admitted at the University of Virginia Clinical Research Unit to undergo an 8-hour metabolic challenge...
September 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28924074/postprandial-glucose-surges-after-extremely-low-carbohydrate-diet-in-healthy-adults
#18
Koji Kanamori, Noriko Ihana-Sugiyama, Ritsuko Yamamoto-Honda, Tomoka Nakamura, Chie Sobe, Shigemi Kamiya, Miyako Kishimoto, Hiroshi Kajio, Kimiko Kawano, Mitsuhiko Noda
Carbohydrate-restricted diets are prevalent not only in obese people but also in the general population to maintain appropriate body weight. Here, we report that extreme carbohydrate restriction for one day affects the subsequent blood glucose levels in healthy adults. Ten subjects (median age 30.5 years, BMI 21.1 kg/m(2), and HbA1c 5.5%), wearing with a continuous glucose monitoring device, were given isoenergetic test meals for 4 consecutive days. On day 1, day 2 (D2), and day 4 (D4), they consumed normal-carbohydrate (63-66% carbohydrate) diet, while on day 3, they took low-carbohydrate/high-fat (5% carbohydrate) diet...
2017: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28902144/implementing-low-cost-community-based-exercise-programs-for-middle-aged-and-older-patients-with-type-2-diabetes-what-are-the-benefits-for-glycemic-control-and-cardiovascular-risk
#19
Romeu Mendes, Nelson Sousa, Victor Machado Reis, Jose Luis Themudo-Barata
BACKGROUND: The purpose of this study was to analyze the effects of a long-term, community-based, combined exercise program developed with low-cost exercise strategies on glycemic control and cardiovascular risk factors in middle-aged and older patients with type 2 diabetes. METHODS: Participants (n = 124; 63.25 ± 7.20 years old) engaged in either a 9-month supervised exercise program (n = 39; consisting of combined aerobic, resistance, agility/balance, and flexibility exercise; three sessions per week; 70 min per session) or a control group (n = 85) who maintained their usual care...
September 13, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28899393/the-mixed-benefit-of-low-lipoprotein-a-in-type-2-diabetes
#20
Michel P Hermans, Sylvie A Ahn, Michel F Rousseau
BACKGROUND: Lipoprotein(a) (Lp(a)), a variant low-density lipoprotein (LDL), is a major genetic risk factor for cardiovascular disease. It is unknown whether an inverse relationship exists between Lp(a) and β-cell function (BCF), as for LDL-cholesterol (LDL-C) lowering by statins. We therefore assessedthe cardiometabolic phenotype of 340 men with type 2 diabetes mellitus (T2DM) in relation to Lp(a), focusing on BCF and hyperbolic product [BxS], which adjusts BCF to insulin sensitivity and secretion...
September 12, 2017: Lipids in Health and Disease
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