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https://www.readbyqxmd.com/read/28729782/holding-strength-of-suture-an-experimental-study-using-porcine-kidney
#1
Ünsal Özkuvanci, Haluk Akpinar, Mert Ali Karadag, Muhammet İrfan Dönmez, Fatih Altunrende
BACKGROUND AND OBJECTIVES: The search for the perfect suture is going on and has resulted in the introduction of many different suture types into the market. The purpose of this study is to investigate the holding strength (HS) of different sutures in the renal parenchyma in an experimental study on pig kidneys. METHODS: The HS that caused sliding of the suture was investigated in 5 adult porcine kidneys with 7 suture variants. HS-caused tearing of the kidney was investigated with 3 suture types on 5 kidneys...
July 2017: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/28723749/effects-of-sealing-the-intramedullary-femoral-canal-in-total-knee-arthroplasty-a-randomized-study
#2
Xu Li, Xiang-Bei Qi, Xue Han, Wei Wang, Jian-Ning Liu, Ji-Chao Guo, Zhi-Yong Li
BACKGROUND: This study investigates the clinical effects of sealing the femoral canal by intramedullary alignment instrumentation in total knee arthroplasty (TKA). METHODS: One hundred twenty consecutive patients with knee osteoarthritis, who underwent unilateral TKA, were enrolled in the study and equally randomized into 2 groups: the sealing group and the control group. In the sealing group, the femoral canal was sealed with autogenous bone and cement using intramedullary alignment instrumentation, while the femoral hole was left open for patients in the control group...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28701670/impact-of-compound-hypertonic-saline-solution-on-decompensated-heart-failure
#3
Yanfang Wan, Lei Li, Heping Niu, Xiaoli Ma, Jing Yang, Chen Yuan, Guichen Mu, Jun Zhang
The aim of the present study was to evaluate the effects of hypertonic saline solution (C-HSS) with high dose furosemide on hospitalization time, readmission, and mortality in patients with New York Heart Association (NYHA) class III heart failure.Decompensated heart failure patients (NYHA III) with chronic ischemic or nonischemic cardiomyopathy and ejection fraction < 40% were divided into 2 groups in an open-label random manner: the first group received a 1-hour intravenous infusion of furosemide (100 mg) plus compound C-HSS (100 mL) twice daily and underwent serious water restriction (500 mL/day); the second group received furosemide intravenous bolus (100 mg) twice a day and water restriction (500 mL/day), without C-HSS...
July 13, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28693888/do-patient-expectations-influence-patient-reported-outcomes-and-satisfaction-in-total-hip-arthroplasty-a-prospective-multicenter-study
#4
Deeptee Jain, Ilya Bendich, Long-Co L Nguyen, Long L Nguyen, Courtland G Lewis, James I Huddleston, Paul J Duwelius, Brian T Feeley, Kevin J Bozic
BACKGROUND: The relationship between patient expectations and patient-reported outcomes (PROs) in total hip arthroplasty (THA) patients is controversial. The purpose of this study was to examine the impact of preoperative patient expectations on postoperative PROs and patient satisfaction. METHODS: This was a prospective multicenter observational cohort study of primary THA patients. Preoperatively, patients completed Hospital for Special Surgery (HSS) Hip Replacement Expectations Survey (expectations), 12 item Short Form Survey (SF-12), University of California, Los Angeles (UCLA) activity score, and Hip Disability and Osteoarthritis Score (HOOS)...
June 16, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28690461/hospital-for-special-surgery-acl-registry-2-year-outcomes-suggest-low-revision-and-return-to-or-rates
#5
Moira McCarthy, Katherine Mallett, Matthew Abola, Sherrie Vassallo, Joseph Nguyen
BACKGROUND: Anterior cruciate ligament (ACL) injuries are among the most common knee injuries. Patient outcomes, rate of subsequent operations, and rate of subsequent ACL reconstruction following primary ACL reconstruction need to be evaluated. QUESTIONS/PURPOSES: This study was designed to answer the following questions: (1) What is the return to surgery (OR) rate following primary ACL reconstruction and (2) what is the revision ACL reconstruction rate? METHODS: Data was drawn from the Hospital for Special Surgery (HSS) ACL Registry...
July 2017: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://www.readbyqxmd.com/read/28689325/factors-affecting-separation-and-detection-of-bile-acids-by-liquid-chromatography-coupled-with-mass-spectrometry-in-negative-mode
#6
Shanshan Yin, Mingming Su, Guoxiang Xie, Xuejing Li, Runmin Wei, Changxiao Liu, Ke Lan, Wei Jia
Bile acids (BAs) are cholesterol metabolites with important biological functions. They undergo extensive host-gut microbial co-metabolisms during the enterohepatic circulation, creating a vast structural diversity and resulting in great challenges to separate and detect them. Based on the bioanalytical reports in the past decade, this work developed three chromatographic gradient methods to separate a total of 48 BA standards on an ethylene-bridged hybrid (BEH) C18 column and high-strength silica (HSS) T3 column and accordingly unraveled the factors affecting the separation and detection of them by liquid chromatography coupled with mass spectrometry (LC-MS)...
July 8, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28689038/a-phylogenetic-view-of-the-out-of-asia-eurasia-and-out-of-africa-hypotheses-in-the-light-of-recent-molecular-and-palaeontological-finds
#7
REVIEW
Úlfur Árnason
The substantiality of the Out of Africa hypothesis was addressed in the light of recent genomic analysis of extant humans (Homo sapiens sapiens, Hss) and progress in Neanderthal palaeontology. The examination lent no support to the commonly assumed Out of Africa scenario but favoured instead a Eurasian divergence between Neanderthals and Hss (the Askur/Embla hypothesis) and an Out of Asia/Eurasia hypothesis according to which all other parts of the world were colonized by Hss migrations from Asia. The examination suggested furthermore that the ancestors of extant KhoeSan and Mbuti composed the first Hss dispersal(s) into Africa and that the ancestors of Yoruba made up a later wave into the same continent...
July 5, 2017: Gene
https://www.readbyqxmd.com/read/28679895/residence-as-a-diagnostic-and-therapeutic-area-a-smart-home-approach
#8
Corinna Mielke, Thorsten Voss, Reinhold Haux
The "research apartment Halberstadtstraße" (HSS) in Braunschweig, Germany, is the attempt to realize a personal living environment as a room for diagnostics and therapy with the support of health-enabling and ambient assistive technologies (HEAAT). As a research tool, the HSS will enable the efficient implementation of new HEAAT and help in evaluating these under controlled real-life conditions. This new research tool will therefore be the missing link between artificial laboratory and complete real-life conditions...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28676850/current-therapeutic-approach-to-hypertrophic-scars
#9
REVIEW
Zrinka Bukvić Mokos, Anamaria Jović, Lovorka Grgurević, Ivo Dumić-Čule, Krešimir Kostović, Romana Čeović, Branka Marinović
Abnormal scarring and its accompanying esthetic, functional, and psychological sequelae still pose significant challe nges. To date, there is no satisfactory prevention or treatment option for hypertrophic scars (HSs), which is mostly due to not completely comprehending the mechanisms underlying their formation. That is why the apprehension of regular and controlled physiological processes of scar formation is of utmost importance when facing hypertrophic scarring, its pathophysiology, prevention, and therapeutic approach...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28659156/the-arm-movement-detection-amd-test-a-fast-robotic-test-of-proprioceptive-acuity-in-the-arm
#10
Leigh Ann Mrotek, Maria Bengtson, Tina Stoeckmann, Lior Botzer, Claude P Ghez, John McGuire, Robert A Scheidt
BACKGROUND: We examined the validity and reliability of a short robotic test of upper limb proprioception, the Arm Movement Detection (AMD) test, which yields a ratio-scaled, objective outcome measure to be used for evaluating the impact of sensory deficits on impairments of motor control, motor adaptation and functional recovery in stroke survivors. METHODS: Subjects grasped the handle of a horizontal planar robot, with their arm and the robot hidden from view...
June 28, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28646508/hepatic-stimulator-substance-resists-hepatic-ischemia-reperfusion-injury-by-regulating-drp1-translocation-and-activation
#11
Chao Zhang, Jing Huang, Wei An
Ischemia-reperfusion injury (IRI), induced by abnormal mitochondrial fission related apoptosis, is a major concern in liver transplantation settings. Our previous studies have demonstrated that hepatic stimulator substance (HSS) is an anti-apoptotic effector and could protect liver from IRI. However, the underlying mechanism remains unclear. In the present study, we report that in vitro and in vivo HSS could regulate mitochondrial fission and hepatocyte apoptosis during liver IRI by orchestrating the translocation and activation of dynamin-related protein 1 (Drp1)...
June 23, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28627051/investigating-the-job-satisfaction-of-healthcare-providers-at%C3%A2-primary-healthcare-centres-in-lebanon-a-national-cross-sectional-study
#12
Mohamad Alameddine, Maysa Baroud, Samer Kharroubi, Randa Hamadeh, Walid Ammar, Hikma Shoaib, Hiba Khodr
Low job satisfaction is linked to higher staff turnover and intensified shortages in healthcare providers (HCP). This study investigates the level of, and factors associated with, HCP job satisfaction in the national primary healthcare (PHC) network in Lebanon. The study adopts a cross-sectional design to survey HCP at 99 PHC centres distributed across the country between October 2013 and May 2014. The study questionnaire consisted of four sections: socio-demographics/professional background, employment characteristics, level of job satisfaction (Measure of Job Satisfaction scale) and level of professional burnout (Maslach Burnout Inventory-HSS scale)...
June 18, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28626303/the-comparison-of-clinical-features-and-quality-of-life-after-total-knee-replacement
#13
Jiyeon Lee, Jung-Hee Kim, Eun-Jung Jung, Byoung-Hee Lee
[Purpose] The purpose of this study is to provide fundamental information for efficient management of patients after a total knee replacement (TKR) through the evaluation of changes of range of motion, pain, functional level, and quality of life. [Subjects and Methods] For a total of 63 knee osteoarthritis patients, VAS, KSKS, KSFS, HSS, WOMAC scores and quality of life were evaluated for functional levels at pre-operation, post-operation, six months after operation, and 12 months after operation. [Results] After the TKR operations, participants showed significant improvement in KSKS, KSFS, WOMAC, and SF-36 scores when compared to pre-operation...
June 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28622027/communicating-with-sensation-seekers-an-fmri-study-of-neural-responses-to-antidrug-public-service-announcements
#14
Lewis Donohew, Michelle DiBartolo, Xun Zhu, Chelsie Benca, Elizabeth Lorch, Seth M Noar, Thomas H Kelly, Jane E Joseph
This study examined the neural basis of processing high- and low-message sensation value (MSV) antidrug public service announcements (PSAs) in high (HSS) and low sensation seekers (LSS) using fMRI. HSS more strongly engaged the salience network when processing PSAs (versus LSS), suggesting that high-MSV PSAs attracted their attention. HSS and LSS participants who engaged higher level cognitive processing regions reported that the PSAs were more convincing and believable and recalled the PSAs better immediately after testing...
June 16, 2017: Health Communication
https://www.readbyqxmd.com/read/28621206/baseline-population-health-conditions-ahead-of-a-health-system-strengthening-program-in-rural-madagascar
#15
Ann C Miller, Ranto H Ramananjato, Andres Garchitorena, Victor R Rabeza, Djordje Gikic, Amber Cripps, Laura Cordier, Hery-Tiana Rahaniraka Razanadrakato, Marius Randriamanambintsoa, Lara Hall, Megan Murray, Felicite Safara Razanavololo, Michael L Rich, Matthew H Bonds
BACKGROUND: A model health district was initiated through a program of health system strengthening (HSS) in Ifanadiana District of southeastern Madagascar in 2014. We report population health indicators prior to initiation of the program. METHODS: A representative household survey based on the Demographic Health Survey was conducted using a two-stage cluster sampling design in two strata - the initial program catchment area and the future catchment area. Chi-squared and t-tests were used to compare data by stratum, using appropriate sampling weights...
2017: Global Health Action
https://www.readbyqxmd.com/read/28601765/application-of-volumetric-absorptive-microsampling-device-for-quantification-of-tacrolimus-in-human-blood-as-a-model-drug-of-high-blood-cell-partition
#16
Kenji Kita, Yuji Mano
Volumetric absorptive microsampling device (VAMS) was evaluated for bioanalysis of tacrolimus, which was used as a model drug with high blood cell partition. Aliquots of blood (ca. 10μL) with different hematocrits and fortified with tacrolimus were wicked up by VAMS and tacrolimus was extracted with a methanol-water mixture (1:1, v/v) via sonication. After chromatography on an AQUITY UPLC HSS T3 column (100×2.1 i.d., mm, 1.8μm), tacrolimus and the internal standard ascomycin, were detected in the positive ion mode with electrospray ionization by monitoring of transitions m/z 826...
September 5, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28591307/schistosomiasis-and-hepatopulmonary-syndrome-the-role-of-concomitant-liver-cirrhosis
#17
Liana Gonçalves-Macedo, Edmundo Pessoa Lopes, Ana Lucia Coutinho Domingues, Brivaldo Markman, Vitor Gomes Mota, Carlos Feitosa Luna
BACKGROUND: Hepatopulmonary syndrome (HPS) is defined as an oxygenation defect induced by intrapulmonary vasodilation in patients with liver disease or portal hypertension. It is investigated in patients with liver cirrhosis and less frequently in those with portal hypertension without liver cirrhosis, as may occur in hepatosplenic schistosomiasis (HSS). OBJECTIVES: To investigate the prevalence of HPS in patients with HSS, and to determine whether the occurrence of HPS is influenced by concomitant cirrhosis...
July 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28590136/controlling-photocatalytic-activity-and-size-selectivity-of-tio2-encapsulated-in-hollow-silica-spheres-by-tuning-silica-shell-structures-using-sacrificial-biomolecules
#18
Kensei Fujiwara, Yasutaka Kuwahara, Yuki Sumida, Hiromi Yamashita
Yolk-shell nanostructured photocatalyst which consists of inner core photocatalytic particles and outer silica shell exhibits high photocatalytic efficiency and molecular size selectivity due to the molecular sieving property of the outer shell. Creation of extended porosity in the shell endows it with improved adsorption properties and size selectivity toward targeted reactants. In this study, yolk-shell nanostructured photocatalyst consisting of TiO2 NPs core and porous silica shell with controllable pore size was fabricated through a facile single-step dual-templating approach utilizing oil-in-water (O/W) microemulsions and amphiphilic protein molecules...
June 14, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28587218/determination-and-pharmacokinetic-study-of-three-diterpenes-in-rat-plasma-by-uhplc-esi-ms-ms-after-oral-administration-of-rosmarinus-officinalis-l-extract
#19
Liqian Wang, Chunli Gan, Zhibin Wang, Lu Liu, Mingjie Gao, Qian Li, Chunjuan Yang
Rosmarinus officinalis L. is commonly used as a spice and flavoring agent. Diterpenes are the main active compounds of R. officinalis. An Ultra High Performance Liquid Chromatography-Tandem Mass Spectrometry (UHPLC-ESI-MS/MS) method was developed for the determination of carnosol, rosmanol, and carnosic acid isolated from R. officinalis in rat plasma, and applied to a pharmacokinetic study after oral administration of R. officinalis extract. Sample preparation involved a liquid-liquid extraction of the analytes with ethyl acetate...
June 4, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28579770/proteasome-activity-related-with-the-daily-physical-activity-of-copd-patients
#20
Kang-Yun Lee, Tzu-Tao Chen, Ling-Ling Chiang, Hsiao-Chi Chuang, Po-Hao Feng, Wen-Te Liu, Kuan-Yuan Chen, Shu-Chuan Ho
BACKGROUND: COPD is a debilitating disease that affects patients' daily lives. One's daily physical activity (DPA) decreases due to multifactorial causes, and this decrease is correlated with a poor prognosis in COPD patients. Muscle wasting may at least be partly due to increased activity of the ubiquitin proteasome pathway and apoptosis. METHODS: This study investigated the relationships among DPA, circulating proteasome activity, and protein carbonyl in COPD patients and healthy subjects (HSs)...
2017: International Journal of Chronic Obstructive Pulmonary Disease
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