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Meijun Liu, Dongbo Shi, Jiang Li
Humanities and Social Sciences (HSS) increasingly absorb knowledge from Hard Sciences, i.e., Science, Technology, Agriculture and Medicine (STAM), as testified by a growing number of citations. However, whether citing more Hard Sciences brings more citations to HSS remains to be investigated. Based on China's HSS articles indexed by the Web of Science during 1998-2014, this paper estimated two-way fixed effects negative binomial models, with journal effects and year effects. Findings include: (1) An inverse U-shaped curve was observed between the percentage of STAM references to the HSS articles and the number of citations they received; (2) STAM contributed increasing knowledge to China's HSS, while Science and Technology knowledge contributed more citations to HSS articles...
2017: PloS One
Gabrielle Lafrenière, Patrick Béliveau, Jean-Yves Bégin, David Simonyan, Sylvain Côté, Valérie Gaudreault, Zeev Israeli, Shahar Lavi, Rodrigo Bagur
AIM: To test the safety and effectiveness of hypertonic saline solution (HSS + F) as a strategy for weight loss and prevention of further deterioration of renal function. METHODS: Patients admitted with acute decompensated heart failure (ADHF) who received HSS + F were included in the study. After a period of a standard ADHF treatment, our patients received an intravenous infusion of furosemide (250 mg) combined with HSS (150 mL of 3% NaCl) twice a day for a mean duration of 2...
August 26, 2017: World Journal of Cardiology
Youguo Ying, Haizhou Xu, Min Yao, Zonghe Qin
BACKGROUND: The purpose of the study is to investigate the role and mechanisms of hydrogen-saturated saline (HSS) in the acute lung injury (ALI) induced by oleic acid (OA) in rats. METHODS: Rats were treated with OA (0.1 mL/kg) to induce ALI and then administered with HSS (5 mL/kg) by intravenous (iv) and intraperitoneal (ip) injection, respectively. Three hours after the injection with OA, the arterial oxygen partial pressure (PaO2), arterial oxygen saturation (SaO2), carbon dioxide partial pressure (PaCO2), and bicarbonate (HCO3(-)) levels were analyzed using blood gas analyzer...
September 19, 2017: Journal of Orthopaedic Surgery and Research
Andreas Fuchs, Helge Eberbach, Kaywan Izadpanah, Gerrit Bode, Norbert P Südkamp, Matthias J Feucht
PURPOSE: To systematically review the results of focal metallic inlay resurfacing prosthesis for the treatment of isolated cartilage defects of the femoral condyles. METHODS: A systematic electronic search of the PubMed database and the Cochrane Library was performed in April 2017 to identify studies that reported clinical or radiographic outcome of focal metallic inlay resurfacing prosthesis for the treatment of isolated cartilage defects of the femoral condyles...
September 16, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Volodymyr Pauk, Tomáš Pluháček, Vladimír Havlíček, Karel Lemr
The ultra-high performance supercritical fluid chromatography-mass spectrometry (UHPSFC/MS) procedure for analysis of native monosaccharides was developed. Chromatographic conditions were investigated to separate a mixture of four hexoses, three pentoses, two deoxyhexoses and two uronic acids. Increasing water content in methanol modifier to 5% and formic acid to 4% improved peak shapes of neutral monosaccharides and allowed complete elution of highly polar uronic acids in a single run. An Acquity HSS C18SB column outperformed other three tested stationary phases (BEH (silica), BEH 2-ethylpyridine, CSH Fluoro-Phenyl) in terms of separation of isomers and analysis time (4...
October 9, 2017: Analytica Chimica Acta
Nour J Youssef, Alain G Rizk, Omar A Ibrahimi, Zeina S Tannous
BACKGROUND The 800 nm long-pulsed diode laser machine is safe and effective for permanent hair reduction. Traditionally, most long-pulsed diode lasers used for hair removal had a relatively small spot size. Recently, a long-pulsed diode laser with a large spot size and vacuum assisted suction handpiece was introduced. The treatment parameters of each type of handpiece differ. Short and long-term clinical efficacy, treatment associated pain, and patient satisfaction are important factors to be considered. OBJECTIVE: This study aims to conduct a direct head to head comparison of both handpieces of the 800nm long-pulsed diode laser by evaluating long term hair reduction, treatment associated pain and patient satisfaction...
September 1, 2017: Journal of Drugs in Dermatology: JDD
M V van Outeren, J H Waarsing, R W Brouwer, J A N Verhaar, M Reijman, S M A Bierma-Zeinstra
OBJECTIVE: No randomized controlled trial (RCT) has compared the high tibial osteotomy (HTO) with non-surgical treatment in patients with medial knee osteoarthritis and varus malalignment. The aim was to compare the effectiveness of an unloader brace treatment or a usual care program to the HTO regarding pain severity and knee function. DESIGN: Surgical treatment (HTO) to two non-surgical options was compared by combining the data of two RCTs. One RCT (n=117) compared an unloader brace to usual care treatment; the other RCT (n=92) compared closing to opening wedge HTO...
September 10, 2017: Osteoarthritis and Cartilage
Sijie Liu, Yongning Wu, Chiguang Fang, Yong Cui, Nan Jiang, Hui Wang
In this study, a highly sensitive and fast method of QuEChERS (acronym of quick, easy, cheap, effective, rugged, safe) combined with isotope dilution-ultra performance liquid chromatography coupled to tandem mass spectrometry was developed for the simultaneous determination of 19 plant growth regulators in plant-originated foods. The samples were initially extracted with acetonitrile containing 1% acetic acid and then the QuEChERS method was applied after the pH value was adjusted to 5.5 - 6.0, using 3-indolepropionic-d2 acid and forchlorfenuron-d5 as internal standard...
2017: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
Federico Roncarolo, Antoine Boivin, Jean-Louis Denis, Rejean Hébert, Pascale Lehoux
BACKGROUND: While there is an extensive literature on Health System (HS) strengthening and on the performance of specific HSs, there are few exhaustive syntheses of the challenges HSs are facing worldwide. This paper reports the findings of a scoping review aiming to classify the challenges of HSs investigated in the scientific literature. Specifically, it determines the kind of research conducted on HS challenges, where it was performed, in which health sectors and on which populations...
September 8, 2017: BMC Health Services Research
Róbert Kormány, Katalin Tamás, Davy Guillarme, Szabolcs Fekete
The goal of the present study was to develop a generic workflow to evaluate the chromatographic resolution in a large design space and easily find some replacement column for the method. To attain this objective from a limited number of initial experiments, modern LC modeling software (Drylab) was employed to study the behaviour of the compounds and visually compare the parts of design spaces obtained with different columns, where a given criterion of critical resolution is fullfilled. A zone of robust space can then easily be found by overlapping design spaces...
September 1, 2017: Journal of Pharmaceutical and Biomedical Analysis
Ya Zheng, Qi Li, Moqian Tian, Weizhi Nan, Guochun Yang, Jin Liang, Xun Liu
Sensation seeking has been associated with substance use and other risk-taking behaviors. The present functional magnetic resonance imaging (fMRI) study investigated the neural correlates underlying risk taking in sensation seeking. Twenty-eight high sensation seekers (HSS; 14 female and 14 male young adults) and 28 low sensation seekers (LSS; 14 female and 14 male young adults) performed an interactive, sequential gambling task that allowed for voluntary pursuit or inhibition of risk taking. Behaviorally, HSS versus LSS exhibited a stronger tendency toward risk taking...
September 8, 2017: Human Brain Mapping
Bingchen Ouyang, Fang Zhou, Le Zhen, Ying Peng, Jianguo Sun, Qianying Chen, Xiaoliang Jin, Guangji Wang, Jingwei Zhang
Tenofovir (TFV), a first-line anti-viral agent, has been prepared as various forms of prodrugs for better bioavailability, lower systemic exposure and higher target cells loading of TFV to enhance efficacy and reduce toxicity. TFV undergoes intracellular phosphorylation to form TFV diphosphate (TFV-DP) in target cell to inhibit viral DNA replication. Hence, TFV-DP is the key active metabolite that exhibits anti-virus activity, its intracellular exposure and half-life determine the final activity. Therefore, simultaneous monitoring prodrug, TFV and TFV-DP in target cells will comprehensively evaluate TFV prodrugs, both considering the stability of ester prodrug, and the intracellular exposure of TFV-DP...
August 30, 2017: Journal of Pharmaceutical and Biomedical Analysis
Shujuan Yang, Chao Yang, Qiang Liao, Wenwen Zhai, Gang Yu, Lin Xiao, Qixing Wang, Yuhan Gong, Suhua Zhang, Yongna Yao, Ke Wang, Ju Wang, Shaochao Bian, Qian Liu
BACKGROUND: Yi people make up about 50% of the population in Liangshan Prefecture, Sichuan Province, China, but accounted for 88.07% of new HIV cases in the prefecture from 2011 to 2013. This study evaluated HIV prevalence in pregnant women of Liangshan Prefecture using HIV sentinel surveillance (HSS) data over the period of 2009 to 2015. METHODS: Xichang, Zhaojue County, and Butuo County were selected as HSS sites. We investigated the temporal trends in HIV prevalence in these areas, and the association between demographic and behavioral characteristics and risk of HIV infection...
2017: PloS One
Lu Jin, Jonas Bemetz, Xia Meng, Hua Wu, Massimo Morbidelli
We have developed a new class of thermoresponsive colloids that can exhibit a sharp reversible transition between dispersion and aggregation in binary BuAc/EtOH solvents based on the UCST (upper critical solution temperature)-type phase separation. This is realized by grafting linear PMMA-BA (random) copolymer onto the colloidal particles. We have selected TiO2/PS hybrid spheres (HSs) as a model system to demonstrate our general design concept. By grafting the linear PMMA-BA copolymer onto the HS surface, with the molecular weight from 30 to 40 kDa, we found that the thermoresponsive transition between dispersion and aggregation is fast, sharp, and reversible...
September 7, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
Shaohua Li, Dawei Chen
Aconitum alkaloid poisoning is a type of poisoning caused by accidental ingestion and clinical use of herbal drugs in many countries. In this study, we developed an in-syringe dispersive micro solid-phase extraction (DMSPE) method for selective extraction of aconitine, benzoylaconine and aconine from human urine using a type of polymer material. All of the parameters influencing the extraction efficiency such as the type and amount of sorbent, the extraction time and the desorption solvent and volume in DMSPE were carefully investigated and optimized...
September 1, 2017: Journal of Analytical Toxicology
Andrés Antonio González-Garrido, Fernando Alejandro Barrios, Fabiola Reveca Gómez-Velázquez, Daniel Zarabozo-Hurtado
Orthographic competence allows automatic word recognition and reading fluency. To elucidate how the orthographic competence in Spanish-speaking adults might affect the neurofunctional mechanisms of visual word recognition, 32 young adults equally divided in two groups (HSS: High Spelling Skills, and LSS: Low Spelling Skills) were evaluated using fMRI methods, while they performed an orthographic recognition task involving pseudohomophones. HSS achieved significantly more correct responses and lower reaction times than LSS...
August 30, 2017: Brain and Language
Ido Lurie
After World War II, traumatic after effects often caused persistent sleep disorders for Holocaust survivors (HSs). This is a review of studies reporting on sleep disturbances and nightmares (as primary or secondary outcomes) among HSs between 1939 and 2015, conducted in various countries and contexts (clinical settings, pension claims, community surveys, sleep laboratories). Most studies revealed various sleep disturbances among HSs. Some studies found those disturbances in the absence of clinical disorders...
September 2017: Journal of Nervous and Mental Disease
Zhibiao Yi, Lin Ma, Baoqiang Wang, Wenxuan Cai, Zheng Xiang
INTRODUCTION: Geraniin has many biological activities including anti-osteoporotic and anti-hyperglycemic efficacies. MATERIALS AND METHODS: A rapid and simple method for the determination of geraniin in rat plasma using ultra performance liquid chromatography coupled to ultraviolet detector was developed. The plasma sample, spiked with epicatechin as an internal standard, was subjected to ethyl acetate extraction prior to analysis. Chromatographic separation was performed on the HSS T3 column and monitored at a wavelength of 280 nm...
August 2017: Current Pharmaceutical Analysis
Mohit Thummar, Prinesh N Patel, S Gananadhamu, R Srinivas
RATIONALE: The presence of impurities and degradation products will affect the pharmacokinetic, pharmacodynamic properties and alter the safety of the drug. Hence, development of stability indicating assay method is an integral part of quality product development and is crucial for the regulatory approval of drug products. METHODS: Acotiamide was subjected to stress degradation under hydrolytic, oxidative, photo and thermal stress conditions. The resulted degradation products (DPs), as well as process related impurity (IMP), were selectively separated from the drug on Waters Acquity HSS cyano column (100 × 2...
August 24, 2017: Rapid Communications in Mass Spectrometry: RCM
Rakshathi Basavaraju, Tarasingh N Sanjay, Urvakhsh M Mehta, Keshavan Muralidharan, Jagadisha Thirthalli
OBJECTIVES: Transcranial magnetic stimulation (TMS)-derived cortical reactivity studies provide a unique opportunity to non-invasively study gamma amino butyric acid (GABA)-mediated inhibitory neurotransmission in bipolar disorder (BD). Earlier studies were conducted in smaller samples and on patients who were on medications that can potentially confound the results. We aimed to study short-interval (SICI) and long-interval intracortical inhibition (LICI) in medication-naïve/free symptomatic (manic) BD patients (n=39), first episode mania (FEM) patients who had recently (≤6 months) remitted with treatment (remitted FEM; n = 28) and healthy subjects (HSs; n = 45)...
August 23, 2017: Bipolar Disorders
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