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https://www.readbyqxmd.com/read/28231704/genetic-correlations-between-behavioural-responses-and-performance-traits-in-laying-hens
#1
Iwona Rozempolska-Rucińska, Grzegorz Zięba, Lucyna Kibała, Tomasz Paweł Próchniak, Marek Łukaszewicz
The aim of the study was to evaluate genetic correlations between the behavioural profile and performance in laying hens as an indirect answer to the question whether the observed behavioural responses are associated with increased levels of stress in these birds. The assessment of birds' temperament was carried out using the Novel Objects Test. The behavioural test was conducted in two successive generations comprising 9483 Rhode Island White birds (approx. 4700 individuals per generation) and 4326 Rhode Island Red birds (approx...
February 23, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28231600/validation-of-the-36-item-version-of-the-who-disability-assessment-schedule-2-0-whodas-2-0-for-assessing-women-s-disability-and-functioning-associated-with-maternal-morbidity
#2
Carla Silveira, Mary Angela Parpinelli, Rodolfo Carvalho Pacagnella, Carla Betina Andreucci, Carina Robles Angelini, Elton Carlos Ferreira, José Guilherme Cecatti
Objective To validate the translation and adaptation to Brazilian Portuguese of 36 items from the World Health Organizaton Disability Assessment Schedule 2.0 (WHODAS 2.0), regarding their content and structure (construct), in a female population after pregnancy. Methods This is a validation of an instrument for the evaluation of disability and functioning and an assessment of its psychometric properties, performed in a tertiary maternity and a referral center specialized in high-risk pregnancies in Brazil...
February 23, 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28231551/acute-effect-of-ozone-exposure-on-daily-mortality-in-seven-cities-of-jiangsu-province-china-no-clear-evidence-for-threshold
#3
Kai Chen, Lian Zhou, Xiaodong Chen, Jun Bi, Patrick L Kinney
BACKGROUND: Few multicity studies have addressed the health effects of ozone in China due to the scarcity of ozone monitoring data. A critical scientific and policy-relevant question is whether a threshold exists in the ozone-mortality relationship. METHODS: Using a generalized additive model and a univariate random-effects meta-analysis, this research evaluated the relationship between short-term ozone exposure and daily total mortality in seven cities of Jiangsu Province, China during 2013-2014...
February 20, 2017: Environmental Research
https://www.readbyqxmd.com/read/28231485/the-importance-of-teacher-support-differential-impacts-by-gender-and-sexuality
#4
Adrienne B Dessel, Alex Kulick, Laura J Wernick, Daniel Sullivan
Teachers play an important role in shaping the experiences of high school students with regard to patterns of heteronormativity and binary gender norms, particularly for lesbian, gay, bisexual, transgender, and questioning (LGBTQ) students. A climate survey of high school students (n = 953) in the United States examined the association between students' well-being and their relationships with teachers. The sample was majority white (65.8%) and multiracial (14.1%). Cisgender (cis)-girls (49.6%), cis-boys (41...
February 20, 2017: Journal of Adolescence
https://www.readbyqxmd.com/read/28231460/delivering-the-sense-of-touch-to-the-human-brain
#5
Radu Darie, Marc Powell, David Borton
Intracortical somatosensory interfaces have now entered the clinical domain. Darie et al. explore the implications of research published in Science Translational Medicine by Flesher et al. (2016), discuss how to design such a system given current technology, and question how to effectively communicate with users about their experience.
February 22, 2017: Neuron
https://www.readbyqxmd.com/read/28231408/climbing-bloom-s-taxonomy-pyramid-lessons-from-a-graduate-histology-course
#6
Nikki B Zaidi, Charles Hwang, Sara Scott, Stefanie Stallard, Joel Purkiss, Michael Hortsch
Bloom's taxonomy was adopted to create a subject-specific scoring tool for histology multiple-choice questions (MCQs). This Bloom's Taxonomy Histology Tool (BTHT) was used to analyze teacher- and student-generated quiz and examination questions from a graduate level histology course. Multiple-choice questions using histological images were generally assigned a higher BTHT level than simple text questions. The type of microscopy technique (light or electron microscopy) used for these image-based questions did not result in any significant differences in their Bloom's taxonomy scores...
February 23, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28231404/express-or-repress-the-transcriptional-dilemma-of-damaged-chromatin
#7
Ilaria Capozzo, Fabio Iannelli, Sofia Francia, Fabrizio d'Adda di Fagagna
The fine modulation of transcriptional activity around DNA lesions is essential to carefully regulate the crosstalk between transcription, the DNA damage response, and DNA repair, particularly when the lesion occurs next to, or within, actively transcribed genes. Recently, several studies have been carried out to investigate how DNA lesions have an impact on local transcription, but the emerging model remains incomplete. Transcription of genes around damaged DNA is actively down-regulated by the DNA damage response through different mechanisms, which appear specific to the chromatin context, the type of DNA damage or its complexity...
February 23, 2017: FEBS Journal
https://www.readbyqxmd.com/read/28231389/response-slykerman-et%C3%A2-al-s-antibiotics-in-the-first-year-of-life-and-subsequent-neurocognitive-outcome
#8
Kate Rylance, Allison Low
We read with interest Slykerman et al's article regarding the effect of antibiotics in infancy on neurocognitive outcomes (1). The abstract suggests evidence of significant findings, however, discussion at our journal club raised a number of questions. This article is protected by copyright. All rights reserved.
February 23, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28231250/corticospinal-excitability-measurements-using-transcranial-magnetic-stimulation-are-valid-with-intramuscular-electromyography
#9
Rebekah L S Summers, Mo Chen, Teresa J Kimberley
OBJECTIVES: Muscular targets that are deep or inaccessible to surface electromyography (sEMG) require intrinsic recording using fine-wire electromyography (fEMG). It is unknown if fEMG validly record cortically evoked muscle responses compared to sEMG. The purpose of this investigation was to establish the validity and agreement of fEMG compared to sEMG to quantify typical transcranial magnetic stimulation (TMS) measures pre and post repetitive TMS (rTMS). The hypotheses were that fEMG would demonstrate excellent validity and agreement compared with sEMG...
2017: PloS One
https://www.readbyqxmd.com/read/28231240/galectin-3-histone-deacetylases-and-hedgehog-signaling-possible-convergent-targets-in-schistosomiasis-induced-liver-fibrosis
#10
REVIEW
Felipe Leite de Oliveira, Katia Carneiro, José Marques Brito, Mariana Cabanel, Jonathas Xavier Pereira, Ligia de Almeida Paiva, Wingkin Syn, Neil C Henderson, Marcia Cury El-Cheikh
Schistosomiasis affects approximately 240 million people in the world. Schistosoma mansoni eggs in the liver induce periportal fibrosis and hepatic failure driven by monocyte recruitment and macrophage activation, resulting in robust Th2 response. Here, we suggested a possible involvement of Galectin-3 (Gal-3), histone deacetylases (HDACs), and Hedgehog (Hh) signaling with macrophage activation during Th1/Th2 immune responses, fibrogranuloma reaction, and tissue repair during schistosomiasis. Gal-3 is highly expressed by liver macrophages (Kupffer cells) around Schistosoma eggs...
February 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28231239/surveillance-for-health-care-access-and-health-services-use-adults-aged-18-64-years-behavioral-risk-factor-surveillance-system-united-states-2014
#11
Catherine A Okoro, Guixiang Zhao, Jared B Fox, Paul I Eke, Kurt J Greenlund, Machell Town
PROBLEM/CONDITION: As a result of the 2010 Patient Protection and Affordable Care Act, millions of U.S. adults attained health insurance coverage. However, millions of adults remain uninsured or underinsured. Compared with adults without barriers to health care, adults who lack health insurance coverage, have coverage gaps, or skip or delay care because of limited personal finances might face increased risk for poor physical and mental health and premature mortality. PERIOD COVERED: 2014...
February 24, 2017: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/28231161/food-leftover-practices-among-consumers-in-selected-countries-in-europe-south-and-north-america
#12
Kadri Koppel, Federica Higa, Sandria Godwin, Nelson Gutierrez, Roman Shalimov, Paula Cardinal, Brizio Di Donfrancesco, Miriam Sosa, Angel A Carbonell-Barrachina, Loreida Timberg, Edgar Chambers
Foodborne illnesses may be related to many food production factors with home practices of consumers playing an important role in food safety. Consumer behavior for handling food leftovers has been studied, however little work on comparisons among countries has been published. The objective of this study was to investigate home food leftover practices of people from North American, South American, and European countries. Surveys were conducted with approximately 100 or more consumers in Argentina, Colombia, the United States, Estonia, Italy, Russia, and Spain...
September 21, 2016: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28231134/motivations-for-food-consumption-during-specific-eating-occasions-in-turkey
#13
Delores Chambers, Uyen T X Phan, Sirichat Chanadang, Curtis Maughan, Karolina Sanchez, Brizio Di Donfrancesco, David Gomez, Federica Higa, Han Li, Edgar Chambers, Eyyup Esen
Several studies in different countries have been conducted to investigate factors affecting food choices. The objective of this study was to understand the motivations of specific food and beverage choices for different eating occasions in a typical diet of the Turkish people. A convenience sample of 141 respondents from seven different geographical regions in Turkey completed an online survey questionnaire that included questions about demographic information and details about their latest eating occasion...
May 24, 2016: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28231021/high-complication-rate-after-introduction-of-transbronchial-cryobiopsy-into-clinical-practice-at-an-academic-medical-center
#14
David M DiBardino, Andrew R Haas, Anthony R Lanfranco, Leslie A Litzky, Daniel Sterman, Jamie L Bessich
RATIONALE: Transbronchial cryobiopsy is an emerging technique for obtaining biopsies of lung parenchyma. Despite limited evidence of safety and efficacy in direct comparison to other available biopsy procedures, pulmonologists are integrating this technique into clinical practice with the hope of avoiding the risks of surgical lung biopsy. OBJECTIVES: To report the rate of severe complications and diagnostic outcomes immediately after introduction of transbronchial cryobiopsy into the clinical practice of a single-center, high-volume, interventional pulmonary group at a large academic medical center in the United States...
February 23, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28230923/predicting-phenotype-from-genotype-improving-accuracy-through-more-robust-experimental-and-computational-modeling
#15
Jonathan Gallion, Amanda Koire, Panagiotis Katsonis, Anne-Marie Schoenegge, Michel Bouvier, Olivier Lichtarge
Computational prediction yields efficient and scalable initial assessments of how variants of unknown significance (VUS) may affect human health. However, when discrepancies between these predictions and direct experimental measurements of functional impact arise, inaccurate computational predictions are frequently assumed as the source. Here we present a methodological analysis indicating that shortcomings in both computational and biological data can contribute to these disagreements. We demonstrate that incomplete assaying of multifunctional proteins can affect the strength of correlations between prediction and experiments; a variant's full impact on function is better quantified by considering multiple assays that probe an ensemble of protein functions...
February 23, 2017: Human Mutation
https://www.readbyqxmd.com/read/28230901/-1-h-nmr-with-multivariate-analysis-for-automobile-lubricant-comparison
#16
Siwon Kim, Dahye Yoon, Dong-Kye Lee, Changshin Yoon, Suhkmann Kim
Identification of suspected automobile-related lubricants could provide valuable information in forensic cases. We examined that automobile lubricants might exhibit the chemometric characteristics to their individual usages. To compare the degree of clustering in the plots, we co-plotted general industrial oils that were highly dissimilar with automobile lubricants in additive compositions. (1) H-NMR spectroscopy was used with multivariate statistics as a tool for grouping, clustering, and identification of automobile lubricants in laboratory conditions...
February 23, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28230899/shared-care-across-the-interface-between-primary-and-specialty-care-in-management-of-long-term-conditions
#17
REVIEW
Susan M Smith, Gráinne Cousins, Barbara Clyne, Shane Allwright, Tom O'Dowd
BACKGROUND: Shared care has been used in the management of many chronic conditions with the assumption that it delivers better care than primary or specialty care alone; however, little is known about the effectiveness of shared care. OBJECTIVES: To determine the effectiveness of shared care health service interventions designed to improve the management of chronic disease across the primary/specialty care interface. This is an update of a previously published review...
February 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28230838/studying-neuroanatomy-using-mri
#18
REVIEW
Jason P Lerch, André J W van der Kouwe, Armin Raznahan, Tomáš Paus, Heidi Johansen-Berg, Karla L Miller, Stephen M Smith, Bruce Fischl, Stamatios N Sotiropoulos
The study of neuroanatomy using imaging enables key insights into how our brains function, are shaped by genes and environment, and change with development, aging and disease. Developments in MRI acquisition, image processing and data modeling have been key to these advances. However, MRI provides an indirect measurement of the biological signals we aim to investigate. Thus, artifacts and key questions of correct interpretation can confound the readouts provided by anatomical MRI. In this review we provide an overview of the methods for measuring macro- and mesoscopic structure and for inferring microstructural properties; we also describe key artifacts and confounds that can lead to incorrect conclusions...
February 23, 2017: Nature Neuroscience
https://www.readbyqxmd.com/read/28230825/molecular-markers-of-apoptosis-in-cancer-patients-exposed-to-ionizing-radiation-the-post-chornobyl-view
#19
A A Philchenkov, E K Balcer-Kubiczek
During the past three decades, the deleterious consequences of Chornobyl accident including carcinogenic effects in the people who were accidentally exposed to radiation have been intensively studied. In particular, recent studies provided increased knowledge of the molecular pathogenesis of thyroid tumors in children exposed to Chornobyl fallout. The risk of several forms of leukemia including myelodysplastic syndromes is elevated in Chornobyl liquidators. Furthermore, the upward trends of increases in a variety of other tumors including breast cancer, cancers of central nervous system and renal cancer have been reported in the persons exposed to Chornobyl fallout...
December 2016: Experimental Oncology
https://www.readbyqxmd.com/read/28230809/association-of-sleep-duration-sleep-quality-and-shift-work-schedule-in-relation-to-hypertension-prevalence-in-chinese-adult-males-a-cross-sectional-survey
#20
Kai Lu, Jia Chen, Li Wang, Changying Wang, Rongjing Ding, Shouling Wu, Dayi Hu
Background: Previous studies indicated that measurement of sleep only by duration and quality may be biased. This study aimed to investigate the interactive association of self-reported sleep duration, quality and shift-work schedule with hypertension prevalence in Chinese adult males. Methods: A total of 4519 Chinese adult males (≥18 years) were enrolled into the cross-sectional survey. Sleep attributes were measured from the responses to the standard Pittsburgh Sleep Quality Index and relevant questions in a structured questionnaire survey...
February 21, 2017: International Journal of Environmental Research and Public Health
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