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multiparametric magnetic resonance imaging

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https://www.readbyqxmd.com/read/28426840/multimodality-multiparametric-brain-tumors-evaluation
#1
Vasiliki Tsitsia, Patricia Svolou, Eftichia Kapsalaki, Kyriaki Theodorou, Katerina Vassiou, Varvara Valotassiou, Panagiotis Georgoulias, Ioannis Fezoulidis, Ioannis Tsougos
Brain tumors represent a vast group of lesions, originating from different neuronal cells with different degrees of aggressiveness. Despite some technological advances either pre or post-treatment, these tumors may share similar imaging findings and properties, rendering diagnosis/prognosis, an ambiguous process. Gadolinium-enhanced magnetic resonance imaging remains the gold standard for providing detailed morphologic information, but presents several limitations due to the overlap of findings, in cases such as progressive tumor and post-radiation related effects...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28424829/-mri-of-the-prostate
#2
D Nörenberg, O Solyanik, B Schlenker, G Magistro, B Ertl-Wagner, D A Clevert, C Stief, M F Reiser, M D'Anastasi
New clinical and technological advances in the field of magnetic resonance imaging (MRI) and targeted image-guided biopsy techniques have significantly improved the detection, localization and staging as well as active surveillance of prostate cancer in recent years. Multiparametric MRI (mpMRI) is currently the main imaging technique for the detection, characterization and diagnostics of metastasizing prostate cancer and is of high diagnostic importance for local staging within the framework of the detection of prostate cancer...
April 19, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28401579/mri-assessment-of-tissue-effects-after-180-w-xps-greenlight-laser-vaporization-of-the-prostate
#3
Romain Huet, Romain Mathieu, Tanguy Rohou, Benoit Peyronnet, Andrea Manunta, Gregory Verhoest, Karim Bensalah, Sebastien Vincendeau
BACKGROUND AND OBJECTIVE: Photoselective vaporization of the prostate (PVP) is an alternative to transurethral resection of the prostate (TURP) in the surgical management of Benign Prostate Obtruction (BPO), with a better hemostatic effect due to a coagulation depth of several millimeters. The objective of this study was to prospectively assess the tissue effects of PVP by Magnetic Resonance Imaging (MRI). MATERIALS AND METHODS: From December to February 2014, ten patients were included in a prospective study and underwent PVP performed by a single surgeon with the Greenlight™ laser 180-W XPS...
April 11, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28400169/combined-clinical-parameters-and-multiparametric-magnetic-resonance-imaging-for-advanced-risk-modeling-of-prostate-cancer-patient-tailored-risk-stratification-can-reduce-unnecessary-biopsies
#4
Jan Philipp Radtke, Manuel Wiesenfarth, Claudia Kesch, Martin T Freitag, Celine D Alt, Kamil Celik, Florian Distler, Wilfried Roth, Kathrin Wieczorek, Christian Stock, Stefan Duensing, Matthias C Roethke, Dogu Teber, Heinz-Peter Schlemmer, Markus Hohenfellner, David Bonekamp, Boris A Hadaschik
BACKGROUND: Multiparametric magnetic resonance imaging (mpMRI) is gaining widespread acceptance in prostate cancer (PC) diagnosis and improves significant PC (sPC; Gleason score≥3+4) detection. Decision making based on European Randomised Study of Screening for PC (ERSPC) risk-calculator (RC) parameters may overcome prostate-specific antigen (PSA) limitations. OBJECTIVE: We added pre-biopsy mpMRI to ERSPC-RC parameters and developed risk models (RMs) to predict individual sPC risk for biopsy-naïve men and men after previous biopsy...
April 8, 2017: European Urology
https://www.readbyqxmd.com/read/28391284/gleason-score-within-prostate-abnormal-areas-defined-by-multiparametric-magnetic-resonance-imaging-did-not-vary-according-to-the-pirads-score
#5
Hakim Slaoui, Yann Neuzillet, Tarek Ghoneim, Mathieu Rouanne, Abdelali Abdou, Pierre Marie Lugagne-Delpon, Antoine Scherrer, Camelia Radulescu, Christian Delancourt, Vincent Molinié, Thierry Lebret
BACKGROUND: We aim to correlate multiparametric magnetic resonance imaging (mpMRI) of the prostate reporting (Prostate Imaging Reporting and Data System [PI-RADS] version 2) with the Gleason score into both radical prostatectomy (RP) specimen and MRI fusion-targeted biopsies (FTB). METHODS: mpMRI of 74 patients who underwent an RP after FTB were retrospectively reviewed. The Gleason score distribution was compared according to the PI-RADS score using the Kruskal-Wallis test...
April 8, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28390098/noninvasive-characterization-of-pancreatic-tumor-mouse-models-using-magnetic-resonance-imaging
#6
Navid Farr, Yak-Nam Wang, Samantha D'Andrea, Kayla M Gravelle, Joo Ha Hwang, Donghoon Lee
The preclinical models of pancreatic adenocarcinoma provide an alternative means for determining the mechanisms of malignancy and possibilities for treatments, thus representing a resource of immense potential for cancer treatment in medicine. To evaluate different tumor models, quantifiable magnetic resonance imaging (MRI) techniques can play a significant role in identifying valuable in vivo biomarkers of tumor characteristics. We characterized three models of pancreatic cancer with multiparametric MRI techniques...
April 7, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28386721/multiparametric-magnetic-resonance-imaging-of-the-prostate-with-computer-aided-detection-experienced-observer-performance-study
#7
Valentina Giannini, Simone Mazzetti, Enrico Armando, Silvia Carabalona, Filippo Russo, Alessandro Giacobbe, Giovanni Muto, Daniele Regge
OBJECTIVES: To compare the performance of experienced readers in detecting prostate cancer (PCa) using likelihood maps generated by a CAD system with that of unassisted interpretation of multiparametric magnetic resonance imaging (mp-MRI). METHODS: Three experienced radiologists reviewed mp-MRI prostate cases twice. First, readers observed CAD marks on a likelihood map and classified as positive those suspicious for cancer. After 6 weeks, radiologists interpreted mp-MRI examinations unassisted, using their favourite protocol...
April 6, 2017: European Radiology
https://www.readbyqxmd.com/read/28385253/prostate-cancer-state-of-the-art-imaging-and-focal-treatment
#8
REVIEW
D A Woodrum, A Kawashima, K R Gorny, L A Mynderse
In 2016, it is estimated 180,890 men are newly diagnosed with prostate cancer and 3,306,760 men live with prostate cancer in the United States. The introduction of multiparametric (mp) magnetic resonance imaging (MRI) of the prostate, standardised interpretation guidelines such as Prostate Imaging Reporting and Data System (PI-RADS version 2), and MRI-based targeted biopsy has improved detection of clinically significant prostate cancer. Accurate risk stratification (Gleason grade/score and tumour stage) using imaging and image-guided targeted biopsy has become critical for the management of patients with prostate cancer...
April 3, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28379863/improved-magnetic-resonance-imaging-pathology-correlation-with-imaging-derived-3d-printed-patient-specific-whole-mount-molds-of-the-prostate
#9
Daniel N Costa, Yonatan Chatzinoff, Niccolo M Passoni, Payal Kapur, Claus G Roehrborn, Yin Xi, Neil M Rofsky, Jose Torrealba, Franto Francis, Cecil Futch, Phyllis Hagens, Hollis Notgrass, Susana Otero-Muinelo, Ivan Pedrosa, Rajiv Chopra
OBJECTIVES: The aim of this study was to compare the anatomical registration of preoperative magnetic resonance imaging (MRI) and prostate whole-mount obtained with 3D-printed, patient-specific, MRI-derived molds (PSM) versus conventional whole-mount sectioning (WMS). MATERIALS AND METHODS: Based on an a priori power analysis, this institutional review board-approved study prospectively included 50 consecutive men who underwent 3 T multiparametric prostate MRI followed by radical prostatectomy...
April 4, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28360260/multiparametric-imaging-of-organ-system-interfaces
#10
Katrien Vandoorne, Matthias Nahrendorf
Cardiovascular diseases are a consequence of genetic and environmental risk factors that together generate arterial wall and cardiac pathologies. Blood vessels connect multiple systems throughout the entire body and allow organs to interact via circulating messengers. These same interactions facilitate nervous and metabolic system's influence on cardiovascular health. Multiparametric imaging offers the opportunity to study these interfacing systems' distinct processes, to quantify their interactions, and to explore how these contribute to cardiovascular disease...
April 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28351193/measurement-of-serum-isoform-2-propsa-derivatives-shows-superior-accuracy-to-magnetic-resonance-imaging-in-the-diagnosis-of-prostate-cancer-in-patients-with-a-total-prostate-specific-antigen-level-of-2-10%C3%A2-ng-ml
#11
Kazuhiro Furuya, Takashi Kawahara, Masaki Narahara, Takashi Tokita, Sachi Fukui, Masashi Imano, Taku Mitome, Yusuke Ito, Koji Izumi, Kimito Osaka, Yumiko Yokomizo, Narihiko Hayashi, Hisashi Hasumi, Shintaro Nawata, Tsuyoshi Kawano, Masahiro Yao, Hiroji Uemura
OBJECTIVE: More accurate diagnostic procedures for prostate cancer are needed to avoid unnecessary biopsy due to the low specificity of prostate-specific antigen (PSA). Recent studies showed that the percentage of serum isoform [-2]proPSA (p2PSA) to free PSA (%p2PSA), the Prostate Health Index (PHI) and magnetic resonance imaging (MRI) were more accurate than PSA. The aim of this study was to test the accuracy of %p2PSA, PHI and MRI in discriminating patients with and without prostate cancer...
March 29, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28350785/the-picture-study-diagnostic-accuracy-of-multiparametric-mri-in-men-requiring-a-repeat-prostate-biopsy
#12
Lucy A M Simmons, Abi Kanthabalan, Manit Arya, Tim Briggs, Dean Barratt, Susan C Charman, Alex Freeman, James Gelister, David Hawkes, Yipeng Hu, Charles Jameson, Neil McCartan, Caroline M Moore, Shonit Punwani, Navin Ramachandran, Jan van der Meulen, Mark Emberton, Hashim U Ahmed
BACKGROUND: Transrectal prostate biopsy has limited diagnostic accuracy. Prostate Imaging Compared to Transperineal Ultrasound-guided biopsy for significant prostate cancer Risk Evaluation (PICTURE) was a paired-cohort confirmatory study designed to assess diagnostic accuracy of multiparametric magnetic resonance imaging (mpMRI) in men requiring a repeat biopsy. METHODS: All underwent 3 T mpMRI and transperineal template prostate mapping biopsies (TTPM biopsies)...
March 28, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28349978/patient-selection-for-prostate-focal-therapy-in-the-era-of-active-surveillance-an-international-delphi-consensus-project
#13
K J Tay, M J Scheltema, H U Ahmed, E Barret, J A Coleman, J Dominguez-Escrig, S Ghai, J Huang, J S Jones, L H Klotz, C N Robertson, R Sanchez-Salas, S Scionti, A Sivaraman, J de la Rosette, T J Polascik
BACKGROUND: Whole-gland extirpation or irradiation is considered the gold standard for curative oncological treatment for localized prostate cancer, but is often associated with sexual and urinary impairment that adversely affects quality of life. This has led to increased interest in developing therapies with effective cancer control but less morbidity. We aimed to provide details of physician consensus on patient selection for prostate focal therapy (FT) in the era of contemporary prostate cancer management...
March 28, 2017: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/28349351/advanced-mri-techniques-in-the-monitoring-of-treatment-of-gliomas
#14
REVIEW
Harpreet Hyare, Steffi Thust, Jeremy Rees
With advances in treatments and survival of patients with glioblastoma (GBM), it has become apparent that conventional imaging sequences have significant limitations both in terms of assessing response to treatment and monitoring disease progression. Both 'pseudoprogression' after chemoradiation for newly diagnosed GBM and 'pseudoresponse' after anti-angiogenesis treatment for relapsed GBM are well-recognised radiological entities. This in turn has led to revision of response criteria away from the standard MacDonald criteria, which depend on the two-dimensional measurement of contrast-enhancing tumour, and which have been the primary measure of radiological response for over three decades...
March 2017: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/28346073/detection-of-clinically-significant-prostate-cancer-short-dual-pulse-sequence-versus-standard-multiparametric-mr-imaging-a-multireader-study
#15
Borna K Barth, Pieter J L De Visschere, Alexander Cornelius, Carlos Nicolau, Hebert Alberto Vargas, Daniel Eberli, Olivio F Donati
Purpose To compare the diagnostic performance of a short dual-pulse sequence magnetic resonance (MR) imaging protocol versus a standard six-pulse sequence multiparametric MR imaging protocol for detection of clinically significant prostate cancer. Materials and Methods This HIPAA-compliant study was approved by the regional ethics committee. Between July 2013 and March 2015, 63 patients from a prospectively accrued study population who underwent MR imaging of the prostate including transverse T1-weighted; transverse, coronal, and sagittal T2-weighted; diffusion-weighted; and dynamic contrast material-enhanced MR imaging with a 3-T imager at a single institution were included in this retrospective study...
March 27, 2017: Radiology
https://www.readbyqxmd.com/read/28344811/the-role-of-imaging-in-the-diagnosis-of-primary-prostate-cancer
#16
Hugh Harvey, Nandita M deSouza
Ultrasound and magnetic resonance imaging (MRI) are key imaging modalities in prostate cancer diagnosis. MRI offers a range of intrinsic contrast mechanisms (T2, diffusion-weighted imaging (DWI), MR spectroscopy (MRS)) and extrinsic contrast-generating options based on tumour vascular state following injection of weakly paramagnetic agents such as gadolinium. Together these parameters are referred to as multiparametric (mp)MRI and are used for detecting and guiding biopsy and staging prostate cancer. Although sensitivity of mpMRI is <75% for disease detection, specificity is >90% and a standardised reporting system together with MR-guided targeted biopsy is the optimal diagnostic pathway...
December 2016: Journal of Clinical Urology
https://www.readbyqxmd.com/read/28336078/what-is-the-negative-predictive-value-of-multiparametric-magnetic-resonance-imaging-in-excluding-prostate-cancer-at-biopsy-a-systematic-review-and-meta-analysis-from-the-european-association-of-urology-prostate-cancer-guidelines-panel
#17
REVIEW
Paul C Moldovan, Thomas Van den Broeck, Richard Sylvester, Lorenzo Marconi, Joaquim Bellmunt, Roderick C N van den Bergh, Michel Bolla, Erik Briers, Marcus G Cumberbatch, Nicola Fossati, Tobias Gross, Ann M Henry, Steven Joniau, Theo H van der Kwast, Vsevolod B Matveev, Henk G van der Poel, Maria De Santis, Ivo G Schoots, Thomas Wiegel, Cathy Yuhong Yuan, Philip Cornford, Nicolas Mottet, Thomas B Lam, Olivier Rouvière
CONTEXT: It remains unclear whether patients with a suspicion of prostate cancer (PCa) and negative multiparametric magnetic resonance imaging (mpMRI) can safely obviate prostate biopsy. OBJECTIVE: To systematically review the literature assessing the negative predictive value (NPV) of mpMRI in patients with a suspicion of PCa. EVIDENCE ACQUISITION: The Embase, Medline, and Cochrane databases were searched up to February 2016. Studies reporting prebiopsy mpMRI results using transrectal or transperineal biopsy as a reference standard were included...
March 20, 2017: European Urology
https://www.readbyqxmd.com/read/28333020/-18-f-choline-positron-emission-tomography-computed-tomography-and-multiparametric-magnetic-resonance-imaging-for-the-detection-of-early-local-recurrence-of-prostate-cancer-initially-treated-by-radiation-therapy-comparison-with-systematic-3-dimensional-transperineal
#18
Salim Kanoun, Paul Walker, Jean-Marc Vrigneaud, Edouard Depardon, Vincent Barbier, Olivier Humbert, Morgan Moulin, Gilles Créhange, Luc Cormier, Romaric Loffroy, François Brunotte, Alexandre Cochet
PURPOSE: To compare the diagnostic performance of (18)F-fluorocholine positron emission tomography/computed tomography (FCH-PET/CT), multiparametric prostate magnetic resonance imaging (mpMRI), and a combination of both techniques for the detection of local recurrence of prostate cancer initially treated by radiation therapy. METHODS AND MATERIALS: This was a retrospective, single-institution study of 32 patients with suspected prostate cancer recurrence who underwent both FCH-PET/CT and 3T mpMRI within 3 months of one another for the detection of recurrence...
April 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28333017/effect-of-prostate-magnetic-resonance-imaging-ultrasound-fusion-guided-biopsy-on-radiation-treatment-recommendations
#19
Aaron Reed, Luca F Valle, Uma Shankavaram, Andra Krauze, Aradhana Kaushal, Erica Schott, Theresa Cooley-Zgela, Bradford Wood, Peter Pinto, Peter Choyke, Baris Turkbey, Deborah E Citrin
PURPOSE: Targeted magnetic resonance imaging (MRI)/ultrasound fusion prostate biopsy (MRI-Bx) has recently been compared with the standard of care extended sextant ultrasound-guided prostate biopsy (SOC-Bx), with the former associated with an increased rate of detection of clinically significant prostate cancer. The present study sought to determine the influence of MRI-Bx on radiation therapy and androgen deprivation therapy (ADT) recommendations. METHODS AND MATERIALS: All patients who had received radiation treatment and had undergone SOC-Bx and MRI-Bx at our institution were included...
April 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28330587/comparison-of-semi-automated-and-manual-methods-to-measure-the-volume-of-prostate-cancer-on-magnetic-resonance-imaging
#20
L Marin, M Ezziane, E Comperat, P Mozer, G Cancel-Tassin, J-F Coté, D Racoceanu, F Boudghene, O Lucidarme, O Cussenot, R Renard Penna
PURPOSE: The purpose of this study was to determine the accuracy of manual semi-automated and volumetric measurements to assess prostate cancer volume on multiparametric magnetic resonance imaging (MP-MRI) using whole-mount histopathology for validation. MATERIALS AND METHODS: We evaluated 30 consecutive men (median age, 65.7 years; interquartile range [IQR], 61.5-70.9 years) with a median prostatic specific antigen of 8.5ng/dL (IQR, 5.5-10.5ng/dL), who underwent MP-MRI before radical prostatectomy...
March 15, 2017: Diagnostic and Interventional Imaging
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