Ahmed Mokhtar, Thomas Arnason, Daniel Gaston, Weei-Yuarn Huang, Heather MacKenzie, Rayan Al-Hazmi, Nadine Vaninetti, Barna Tugwell, Daniel Rayson
BACKGROUND: Approximately 30% of neuroendocrine tumors (NETs) present with secretory syndromes or develop one during the course of the disease. Cushing syndrome caused by a gastrointestinal tract NET is rare, with limited published information. We describe a patient with florid Cushing syndrome due to ectopic adrenocorticotropic hormone (ACTH) from a NET of colonic origin. A literature review was conducted to describe the spectrum of this clinical and pathologic entity as reported in the scientific literature...
March 2019: Clinical Colorectal Cancer