Ghada El-Hajj Fuleihan, Marlene Chakhtoura, Cristiana Cipriani, Richard Eastell, Tatiana Karonova, Jian-Min Liu, Salvatore Minisola, Ambrish Mithal, Carolina A Moreira, Munro Peacock, Marian Schini, Barbara Silva, Marcella Walker, Ola El Zein, Claudio Marcocci
This narrative review summarizes data on classical and nonclassical manifestations of primary hyperparathyroidism (PHPT). It is based on a rigorous literature search, inclusive of a Medline search for systematic reviews from 1940 to December 2020, coupled with a targeted search for original publications, covering four databases, from January 2013-December 2020, and relevant articles from authors' libraries. We present the most recent information, identify knowledge gaps, and suggest a research agenda. The shift in the presentation of PHPT from a predominantly symptomatic to an asymptomatic disease, with its varied manifestations, has presented several challenges...
November 2022: Journal of Bone and Mineral Research