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https://read.qxmd.com/read/24070911/high-dose-atorvastatin-reduces-periodontal-inflammation-a-novel-pleiotropic-effect-of-statins
#1
RANDOMIZED CONTROLLED TRIAL
Sharath Subramanian, Hamed Emami, Esad Vucic, Parmanand Singh, Jayanthi Vijayakumar, Kenneth M Fifer, Achilles Alon, Sudha S Shankar, Michael Farkouh, James H F Rudd, Zahi A Fayad, Thomas E Van Dyke, Ahmed Tawakol
OBJECTIVES: The purpose of this study was to test whether high-dose statin treatment would result in a reduction in periodontal inflammation as assessed by (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET)/computed tomography (CT). BACKGROUND: Periodontal disease (PD) is an independent risk factor for atherosclerosis. METHODS: Eighty-three adults with risk factors or with established atherosclerosis and who were not taking high-dose statins were randomized to atorvastatin 80 mg vs...
December 24, 2013: Journal of the American College of Cardiology
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