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Infections

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260 papers 100 to 500 followers
By M KKhan Pediatric Intensivist
https://www.readbyqxmd.com/read/29440502/influenza-associated-pediatric-deaths-in-the-united-states-2010-2016
#1
Mei Shang, Lenee Blanton, Lynnette Brammer, Sonja J Olsen, Alicia M Fry
BACKGROUND: Influenza-associated pediatric deaths became a notifiable condition in the United States in 2004. METHODS: We analyzed deaths in children aged <18 years with laboratory-confirmed influenza virus infection reported to the Centers for Disease Control and Prevention during the 2010-2011 to 2015-2016 influenza seasons. Data were collected with a standard case report form that included demographics, medical conditions, and clinical diagnoses. RESULTS: Overall, 675 deaths were reported...
April 2018: Pediatrics
https://www.readbyqxmd.com/read/29298496/tuberculosis-testing-in-children
#2
Jessica L Coleman, Barley R Halton, Russell W Steele
No abstract text is available yet for this article.
January 1, 2018: Clinical Pediatrics
https://www.readbyqxmd.com/read/29462280/clinical-practice-guidelines-for-clostridium-difficile-infection-in-adults-and-children-2017-update-by-the-infectious-diseases-society-of-america-idsa-and-society-for-healthcare-epidemiology-of-america-shea
#3
L Clifford McDonald, Dale N Gerding, Stuart Johnson, Johan S Bakken, Karen C Carroll, Susan E Coffin, Erik R Dubberke, Kevin W Garey, Carolyn V Gould, Ciaran Kelly, Vivian Loo, Julia Shaklee Sammons, Thomas J Sandora, Mark H Wilcox
A panel of experts was convened by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) to update the 2010 clinical practice guideline on Clostridium difficile infection (CDI) in adults. The update, which has incorporated recommendations for children (following the adult recommendations for epidemiology, diagnosis, and treatment), includes significant changes in the management of this infection and reflects the evolving controversy over best methods for diagnosis...
February 15, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/21873693/urinary-tract-infection-clinical-practice-guideline-for-the-diagnosis-and-management-of-the-initial-uti-in-febrile-infants-and-children-2-to-24-months
#4
Kenneth B Roberts
OBJECTIVE: To revise the American Academy of Pediatrics practice parameter regarding the diagnosis and management of initial urinary tract infections (UTIs) in febrile infants and young children. METHODS: Analysis of the medical literature published since the last version of the guideline was supplemented by analysis of data provided by authors of recent publications. The strength of evidence supporting each recommendation and the strength of the recommendation were assessed and graded...
September 2011: Pediatrics
https://www.readbyqxmd.com/read/29384980/infectious-diseases-consultation-improves-treatment-and-decreases-mortality-by-enterococcal-bacteremia-in-children
#5
Munehiro Furuichi, Mihoko Furuichi, Yuho Horikoshi, Isao Miyairi
BACKGROUND: Enterococci can cause severe infectious diseases. Delaying appropriate antibiotic therapy for enterococcal bacteremia is associated with increased patient mortality. METHODS: We conducted a retrospective analysis examining the characteristics of children with enterococcal bacteremia at the two largest children's hospitals in Japan. We compared outcomes of enterococcal bacteremia patients who received infectious diseases (ID) consultation with those who did not...
January 29, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28687212/sepsis-and-challenging-infections-in-the-immunosuppressed-patient-in-the-intensive-care-unit
#6
REVIEW
Diana F Florescu, Uriel Sandkovsky, Andre C Kalil
In 2017, most intensive care units (ICUs) worldwide are admitting a growing population of immunosuppressed patients. The most common causes of pre-ICU immunosuppression are solid organ transplantation, hematopoietic stem cell transplantation, and infection due to human immunodeficiency virus. In this article, the authors review the most frequent infections that cause critical care illness in each of these 3 immunosuppressed patient populations.
September 2017: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/28687213/prevention-of-central-line-associated-bloodstream-infections
#7
REVIEW
Taison Bell, Naomi P O'Grady
Central venous catheters (CVCs) are commonly used in critically ill patients and offer several advantages to peripheral intravenous access. However, indwelling CVCs have the potential to lead to bloodstream infections, with the risk increasing with an array of characteristics, such as catheter choice, catheter location, insertion technique, and catheter maintenance. Evidence-based guidelines have led to a significant reduction in the incidence of bloodstream infections associated with CVCs. The combination of guideline implementation and newer technologies has the potential to further reduce morbidity and mortality from infections related to CVCs...
September 2017: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/28687214/severe-respiratory-viral-infections-new-evidence-and-changing-paradigms
#8
REVIEW
James M Walter, Richard G Wunderink
Lower respiratory tract infection is a leading cause of death in the United States. Advances in diagnostic testing have improved our ability to detect pathogens. Viral pathogens are important causal pathogens in immunocompetent patients. As the number of elderly adults and those with chronic medical conditions increases, the burden of viral respiratory infections will increase. Clinicians must be familiar with the characteristics of rhinovirus, human adenoviruses, respiratory syncytial virus, and human metapneumovirus...
September 2017: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/28687215/invasive-fungal-infections-in-the-intensive-care-unit
#9
REVIEW
Luis Ostrosky-Zeichner, Mohanad Al-Obaidi
Patients in the intensive care unit are exposed to multiple stressors that predispose them to invasive fungal infections (IFIs), which carry high morbidity and mortality. Getting acquainted with the diagnostic methods and therapies is imperative for patient safety and for providing high-quality health care. This article focuses on the most frequent IFIs: invasive candidiasis and invasive aspergillosis.
September 2017: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/28779833/high-containment-pathogen-preparation-in-the-intensive-care-unit
#10
REVIEW
Brian T Garibaldi, Daniel S Chertow
The recent Ebola virus disease outbreak highlighted the need to build national and worldwide capacity to provide care for patients with highly infectious diseases. Specialized biocontainment units were successful in treating several critically ill patients with Ebola virus disease both in the United States and Europe. Several key principles underlie the care of critically ill patients in a high-containment environment. Environmental factors, staffing, equipment, training, laboratory testing, procedures, and waste management each present unique challenges...
September 2017: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/29269189/pediatric-community-acquired-pneumonia-in-the-united-states-changing-epidemiology-diagnostic-and-therapeutic-challenges-and-areas-for-future-research
#11
REVIEW
Sophie E Katz, Derek J Williams
Community-acquired pneumonia (CAP) is one of the most common serious infections in childhood. This review focuses on pediatric CAP in the United States and other industrialized nations, specifically highlighting the changing epidemiology of CAP, diagnostic and therapeutic challenges, and areas for further research.
March 2018: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/29406977/emerging-respiratory-viruses-in-children
#12
REVIEW
Jennifer E Schuster, John V Williams
Respiratory viral infections are a leading cause of pediatric disease. Emerging respiratory viruses can cause outbreaks with significant morbidity and mortality or circulate routinely. The rapid identification of pathogens, epidemiologic tracing, description of symptoms, and development of preventative and therapeutic measures are crucial to limiting the spread of these viruses. Some emerging viruses, such as rhinovirus C and influenza C, circulate yearly but were previously undetected due to limited diagnostic methods...
March 2018: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/29221616/dengue-fever-report-from-the-task-force-on-tropical-diseases-by-the-world-federation-of-societies-of-intensive-and-critical-care-medicine
#13
REVIEW
Pravin Amin, Özlem Acicbe, Jorge Hidalgo, Juan Ignacio Silesky Jiménez, Tim Baker, Guy A Richards
Dengue is an arbovirus affecting humans and spread by mosquitoes. Severe dengue follows a secondary infection with a different virus serotype. The problem is truly global as it is endemic in over 100 countries. Severe dengue can be a life-threatening because of increased vascular permeability, resulting in leakage of fluid from the intravascular compartment to the extravascular space. When major bleeding does occur, it is almost invariably combined with profound shock since this, in combination with thrombocytopenia, hypoxia, and acidosis, can lead to multiple organ failure and disseminated intravascular coagulation...
February 2018: Journal of Critical Care
https://www.readbyqxmd.com/read/29333566/principles-of-management-of-central-nervous-system-infections
#14
REVIEW
Sunit Singhi, Suresh Kumar Angurana
CNS infections in children are medical emergency and are associated with high mortality and morbidity. For diagnosis, a high index of suspicion is required. Clinical assessment should be supplemented by laboratory investigations including CSF Gram stain and cultures, blood culture, PCR on CSF, serological tests, and imaging. Commonly associated life threatening complications include coma, seizure, raised intracranial pressure (ICP), focal deficits, shock, respiratory failure, and fluid and electrolyte abnormalities...
January 15, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29480032/current-and-future-treatment-options-for-community-associated-mrsa-infection
#15
A Khan, B Wilson, I M Gould
Community-associated MRSA (CA-MRSA) represents a global epidemic which beautifully encapsulates the fascinating ability of bacterial organisms to adapt quickly on an evolutionary basis to the extreme selective pressure of antibiotic exposure. In stark contrast to Healthcare-associated MRSA (HA-MRSA), it has become apparent that CA-MRSA is less straight forward of a challenge in terms of controlling its transmission, and has forced clinicians to adjust empiric management of clinical syndromes such as skin and soft tissue infection (SSTI) as well as pneumonia...
April 2018: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/29288160/committee-on-infectious-diseases-recommendations-for-prevention-and-control-of-influenza-in-children-2017-2018-pediatrics-2017-140-4-e20172550
#16
(no author information available yet)
No abstract text is available yet for this article.
January 2018: Pediatrics
https://www.readbyqxmd.com/read/29249277/rifampicin-for-staphylococcus-aureus-bacteraemia-give-it-arrest
#17
Thomas L Holland, Vance G Fowler
No abstract text is available yet for this article.
December 14, 2017: Lancet
https://www.readbyqxmd.com/read/29194529/2017-infectious-diseases-society-of-america-clinical-practice-guidelines-for-the-diagnosis-and-management-of-infectious-diarrhea
#18
Andi L Shane, Rajal K Mody, John A Crump, Phillip I Tarr, Theodore S Steiner, Karen Kotloff, Joanne M Langley, Christine Wanke, Cirle Alcantara Warren, Allen C Cheng, Joseph Cantey, Larry K Pickering
These guidelines are intended for use by healthcare professionals who care for children and adults with suspected or confirmed infectious diarrhea. They are not intended to replace physician judgement regarding specific patients or clinical or public health situations. This document does not provide detailed recommendations on infection prevention and control aspects related to infectious diarrhea.
November 29, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29356694/the-optimal-duration-of-treatment-for-skin-and-soft-tissue-infections-and-acute-bacterial-skin-and-skin-structure-infections
#19
Silvia Corcione, Francesco Giuseppe De Rosa
PURPOSE OF REVIEW: To summarize the current finding on SSTIs/ABSSSIs treatment duration. RECENT FINDINGS: In 2013, the FDA approved the definition of acute bacterial skin and skin structure infections (ABSSSIs). From a clinical point of view, the new definition may present some advantages: the definition of the severity of the disease, the measurement of reduction in lesion size, and effectiveness of treatment primary endpoint at 48-72 h after treatment initiation...
April 2018: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/29305250/diagnosis-and-treatment-of-urinary-tract-infections-across-age-groups
#20
REVIEW
Christine M Chu, Jerry L Lowder
Urinary tract infections are the most common outpatient infections, but predicting the probability of urinary tract infections through symptoms and test results can be complex. The most diagnostic symptoms of urinary tract infections include change in frequency, dysuria, urgency, and presence or absence of vaginal discharge, but urinary tract infections may present differently in older women. Dipstick urinalysis is popular for its availability and usefulness, but results must be interpreted in context of the patient's pretest probability based on symptoms and characteristics...
January 2, 2018: American Journal of Obstetrics and Gynecology
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