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Thyroid cancer

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8 papers 0 to 25 followers
Yuri E Nikiforov, Raja R Seethala, Giovanni Tallini, Zubair W Baloch, Fulvio Basolo, Lester D R Thompson, Justine A Barletta, Bruce M Wenig, Abir Al Ghuzlan, Kennichi Kakudo, Thomas J Giordano, Venancio A Alves, Elham Khanafshar, Sylvia L Asa, Adel K El-Naggar, William E Gooding, Steven P Hodak, Ricardo V Lloyd, Guy Maytal, Ozgur Mete, Marina N Nikiforova, Vania Nosé, Mauro Papotti, David N Poller, Peter M Sadow, Arthur S Tischler, R Michael Tuttle, Kathryn B Wall, Virginia A LiVolsi, Gregory W Randolph, Ronald A Ghossein
IMPORTANCE: Although growing evidence points to highly indolent behavior of encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC), most patients with EFVPTC are treated as having conventional thyroid cancer. OBJECTIVE: To evaluate clinical outcomes, refine diagnostic criteria, and develop a nomenclature that appropriately reflects the biological and clinical characteristics of EFVPTC. DESIGN, SETTING, AND PARTICIPANTS: International, multidisciplinary, retrospective study of patients with thyroid nodules diagnosed as EFVPTC, including 109 patients with noninvasive EFVPTC observed for 10 to 26 years and 101 patients with invasive EFVPTC observed for 1 to 18 years...
August 1, 2016: JAMA Oncology
Qiang Zhang, Shuai Yang, Xian-ying Meng, Guang Chen, Ren-zhu Pang
OBJECTIVE: To analyze the clinical characteristics of familial nonmedullary thyroid carcinoma (FNMTC), in order to provide evidence for early diagnosis and treatment. METHODS: We retrospectively investigated the inpatients between September 2006 and September 2013 in the First Bethune Hospital of Jilin University, in which 78 patients with FNMTC from 31 families were analyzed by a comparison with 3445 control cases from the patients with sporadic nonmedullary thyroid carcinoma (SNMTC)...
March 2016: World Journal of Surgery
Jun Cao, Can Chen, Chao Chen, Qing-Liang Wang, Ming-Hua Ge
OBJECTIVE: It remains controversial whether or not the aggressiveness of familial nonmedullary thyroid cancer (FNMTC) differs from sporadic carcinoma. The aim of this study was to determine the clinicopathological features and prognosis of FNMTC. DESIGN: A matched-case comparative study. METHODS: Three hundred and seventy-two patients with familial papillary thyroid carcinoma (FPTC) were enrolled as the study group, and another 372 patients with sporadic PTC were enrolled as controls and matched for gender, age, tumour/node/metastasis (TNM) staging and approximate duration of follow-up...
April 2016: Clinical Endocrinology
Antonio Ríos, J M Rodríguez, D Navas, A Cepero, N M Torregrosa, M D Balsalobre, P Parrilla
INTRODUCTION: Blood relatives of patients with familial papillary thyroid carcinoma (FPTC) have a higher rate of thyroid disease. This study analyzed the utility of a screening protocol for thyroid disease on blood relatives of patients with FPTC. METHODS: <AbstractText Label="STUDY POPULATION" NlmCategory="METHODS">Members of families diagnosed with FPTC. INCLUSION CRITERIA: (1) first- and second-degree relatives; and (2) older than age 11 years...
August 2016: Annals of Surgical Oncology
Xiaofei Wang, Wenli Cheng, Jingdong Li, Anping Su, Tao Wei, Feng Liu, Jingqiang Zhu
OBJECTIVE: There is controversy as to whether familial nonmedullary thyroid carcinoma (FNMTC) is more aggressive than sporadic NMTC (SNMTC). The aim of the study was to evaluate the biological characteristics of patients with FNMTC by a meta-analysis. METHODS: Four databases (PubMed, EMBASE, the Cochrane library databases, and the Web of Science) were searched to identify studies published before September, 2014. All original studies that compared clinical characteristics and prognosis of patients with FNMTC and SNMTC were included...
June 2015: European Journal of Endocrinology
Hyeong Sik Ahn, Hyun Jung Kim, Kyoung Hoon Kim, Young Sung Lee, Seung Jin Han, Yuri Kim, Min Ji Ko, Juan P Brito
BACKGROUND: The incidence of thyroid cancer has increased worldwide. The country where the incidence has increased most is South Korea. The goal of this study is to understand the magnitude of association between opportunistic thyroid cancer screening and thyroid cancer incidence, thyroid cancer subtype, and disease-specific mortality. METHODS: We used the 2010 Korea Community Health Survey, which queried 226,873 individuals if they had been screened for thyroid cancer in the last two years...
November 2016: Thyroid: Official Journal of the American Thyroid Association
Young Jun Choi, Jung Hwan Baek, Chong Hyun Suh, Woo Hyun Shim, Boseul Jeong, Jae Kyun Kim, Dong Eun Song, Tae Yong Kim, Ki-Wook Chung, Jeong Hyun Lee
BACKGROUND: The purpose of this study was to evaluate the role of core-needle biopsy (CNB) by comparing the results of CNB and repeat fine-needle aspiration (FNA) for thyroid nodules that are initially read as atypia/follicular lesion of undetermined significance (AUS/FLUS) on FNA. METHODS: Among 2631 initial AUS/FLUS FNA results, 505 consecutive nodules (295 repeat FNAs and 210 CNBs) were retrospectively analyzed. The primary outcome was inconclusive (ie, nondiagnostic or AUS/FLUS)...
February 2017: Head & Neck
Joseph Scharpf, Michael Tuttle, Richard Wong, Drew Ridge, Russell Smith, Dana Hartl, Robert Levine, Gregory Randolph
This American Head and Neck Society (AHNS) consensus statement focuses on the detection and management of recurrent thyroid cancer. This document describes the radiologic approach to defining structural recurrent disease and the operative and nonoperative rationale in addressing identified structural disease to create equipoise in the personalized treatment strategy for the patient. The recommendations of this AHNS multidisciplinary consensus panel of the American Head and Neck Society are intended to help guide all multidisciplinary clinicians who diagnose or manage adult patients with thyroid cancer...
December 2016: Head & Neck
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