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Viraje a mania o hipomania

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2 papers 0 to 25 followers
Giulio Perugi, Michele Fornaro, Hagop S Akiskal
The constructs of atypical depression, bipolar II disorder and borderline personality disorder (BPD) overlap. We explored the relationships between these constructs and their temperamental underpinnings. We examined 107 consecutive patients who met DSM-IV criteria for major depressive episode with atypical features. Those who also met the DSM-IV criteria for BPD (BPD+), compared with those who did not (BPD-), had a significantly higher lifetime comorbidity for body dysmorphic disorder, bulimia nervosa, narcissistic, dependent and avoidant personality disorders, and cyclothymia...
February 2011: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
R M Post, L L Altshuler, G S Leverich, M A Frye, W A Nolen, R W Kupka, T Suppes, S McElroy, P E Keck, K D Denicoff, H Grunze, J Walden, C M R Kitchen, J Mintz
BACKGROUND: Few studies have examined the relative risks of switching into hypomania or mania associated with second-generation antidepressant drugs in bipolar depression. AIMS: To examine the relative acute effects of bupropion, sertraline and venlafaxine as adjuncts to mood stabilisers. METHOD: In a 10-week trial, participants receiving out-patient treatment for bipolar disorder (stratified for rapid cycling) were randomly treated with a flexible dose of one of the antidepressants, or their respective matching placebos, as adjuncts to mood stabilisers...
August 2006: British Journal of Psychiatry: the Journal of Mental Science
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