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Allergy testing

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3 papers 0 to 25 followers
Jörg Kleine-Tebbe, Paolo M Matricardi, Robert G Hamilton
Symptoms are recorded by obtaining a clinical history. Allergen sensitization is demonstrated by skin prick test or allergen-specific IgE serology. IgE sensitizations to allergen sources can be identified knowing the relationship between major aeroallergens and homologous allergen families. Some develop allergic sensitization to pan-allergens. Allergen extracts do not allow definitive separation of the sources. IgE antibody analysis of the major allergenic molecules facilitates differentiation of sensitizing allergen sources...
February 2016: Immunology and Allergy Clinics of North America
P M Matricardi, J Kleine-Tebbe, H J Hoffmann, R Valenta, C Hilger, S Hofmaier, R C Aalberse, I Agache, R Asero, B Ballmer-Weber, D Barber, K Beyer, T Biedermann, M B Bilò, S Blank, B Bohle, P P Bosshard, H Breiteneder, H A Brough, L Caraballo, J C Caubet, R Crameri, J M Davies, N Douladiris, M Ebisawa, P A EIgenmann, M Fernandez-Rivas, F Ferreira, G Gadermaier, M Glatz, R G Hamilton, T Hawranek, P Hellings, K Hoffmann-Sommergruber, T Jakob, U Jappe, M Jutel, S D Kamath, E F Knol, P Korosec, A Kuehn, G Lack, A L Lopata, M Mäkelä, M Morisset, V Niederberger, A H Nowak-Węgrzyn, N G Papadopoulos, E A Pastorello, G Pauli, T Platts-Mills, D Posa, L K Poulsen, M Raulf, J Sastre, E Scala, J M Schmid, P Schmid-Grendelmeier, M van Hage, R van Ree, S Vieths, R Weber, M Wickman, A Muraro, M Ollert
The availability of allergen molecules ('components') from several protein families has advanced our understanding of immunoglobulin E (IgE)-mediated responses and enabled 'component-resolved diagnosis' (CRD). The European Academy of Allergy and Clinical Immunology (EAACI) Molecular Allergology User's Guide (MAUG) provides comprehensive information on important allergens and describes the diagnostic options using CRD. Part A of the EAACI MAUG introduces allergen molecules, families, composition of extracts, databases, and diagnostic IgE, skin, and basophil tests...
May 2016: Pediatric Allergy and Immunology
Amandine Chauveau, Marie-Laure Dalphin, Vincent Kaulek, Caroline Roduit, Aurore Pugin, Erika von Mutius, Dominique Angèle Vuitton, Jean-Charles Dalphin
BACKGROUND: Accurate diagnosis of allergic sensitization is essential in clinical practice and allergy research, and the choice of assessment method may have an important impact. The PASTURE study (Protection against Allergy: Study of Rural Environment) examines the influence of exposure to a dairy farm environment on the occurrence of allergy in a cohort of rural European children from birth to 10 years. The aim of our study was to analyze agreement between skin prick tests (SPTs), to aeroallergens and food allergens, and specific IgE and to evaluate the association of SPT with atopic dermatitis in the 204 French children of the PASTURE study...
2016: International Archives of Allergy and Immunology
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