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8 papers 0 to 25 followers
Colin Reardon
Communication between the nervous and immune systems can significantly alter immune cell function in a number of inflammatory diseases. Elegant studies have defined a basic functional circuit in a "cholinergic anti-inflammatory pathway" that highlights a unique role for the vagus nerve, and has brought about a resurgence in the field of neuro-immunology. This research has further identified that in addition to tonic signals that can restrain immune cell activation; the anti-inflammatory reflex arc is amiable to targeted stimulation as a therapeutic modality...
October 2016: Immunology Letters
Hosan Kim, Soon Park, Greggory Housler, Vanessa Marcel, Sue Cross, Mina Izadjoo
Novel approaches including nonpharmacological methodologies for prevention and control of microbial pathogens and emerging antibiotic resistance are urgently needed. Procellera is a wound care device consisting of a matrix of alternating silver (Ag) and zinc (Zn) dots held in position on a polyester substrate with a biocompatible binder. This electroceutical medical device is capable of generating a direct current voltage (0.5-0.9 Volts). Wound dressings containing metals such as Ag and/or Zn as active ingredients are being used for control of colonized and infected wounds...
May 2016: Military Medicine
J F Guest, N Ayoub, T Greaves
OBJECTIVE: To estimate the cost-effectiveness of treating patients with a venous leg ulcer (VLU) with an externally applied electroceutical (EAE) device, plus dressings and compression bandaging or continuing with their previous care plan, from the perspective of the National Health Service (NHS) in the UK. METHOD: This was a prospective, single-arm, non-blinded, clinical and economic evaluation of EAE therapy performed in 2013/14. Patients' VLUs were treated with six active units of EAE therapy (each unit for two days) plus dressings and compression bandaging over a period of 12 days...
December 2015: Journal of Wound Care
Piya Das Ghatak, Richard Schlanger, Kasturi Ganesh, Lynn Lambert, Gayle M Gordillo, Patsy Martinsek, Sashwati Roy
Objective: To test whether the use of a wireless electroceutical dressing (WED) (Procellera(®)) in conjunction with a 5-day negative pressure wound therapy (NPWT) may reduce the number of dressing changes required per week with this therapy. Approach: At the Ohio State University Comprehensive Wound Center, chronic wound patients (n=30) undergoing NPWT were randomized into two arms following consent as approved by the institutional review board. The control arm received standard of care NPWT, where the dressing change was performed thrice a week...
May 1, 2015: Advances in Wound Care
Gunjan Sinha
No abstract text is available yet for this article.
March 2015: Nature Biotechnology
Frankie James Rawson
No abstract text is available yet for this article.
January 2015: Therapeutic Delivery
Lawrence Steinman
No abstract text is available yet for this article.
February 2015: Brain, Behavior, and Immunity
Gunjan Sinha
No abstract text is available yet for this article.
June 2013: Nature Medicine
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