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6 papers 0 to 25 followers
https://www.readbyqxmd.com/read/28012935/idiopathic-systemic-capillary-leak-syndrome-clarkson-disease
#1
Kirk M Druey, Samir M Parikh
In 1960, Dr. Bayard Clarkson described a woman experiencing sporadic, recurrent episodes of shock and anasarca. Plasma from an acute attack induced a "shock"-like syndrome when injected into rats. The enigmatic "Systemic Capillary Leak Syndrome" (SCLS) named for Dr. Clarkson is characterized by transient and severe, but reversible, hemoconcentration and hypoalbuminemia due to leakage of fluids and macromolecules into tissues. Although < 500 cases of SCLS have been reported in the literature since 1960, the condition is probably under-diagnosed due to lack of awareness and a high mortality without treatment...
December 21, 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27997286/kounis-syndrome-following-canned-tuna-fish-ingestion
#2
Luisa De Gennaro, Natale Daniele Brunetti, Nicola Locuratolo, Massimo Ruggiero, Manuela Resta, Giuseppe Diaferia, Michele Rana, Pasquale Caldarola
Kounis syndrome (KS) is a complex of cardiovascular symptoms and signs following either allergy or hypersensitivity and anaphylactic or anaphylactoid insults. We report the case of 57-year-old man, with hypertension and history of allergy, referred for facial rash and palpitations appeared after consumption of canned tuna fish. Suddenly, the patient collapsed: electrocardiogram showed ST-elevation in inferior leads. The patient was transferred from the spoke emergency room for coronary angio, which did not show any sign of coronary atherosclerosis...
December 20, 2016: Acta Clinica Belgica
https://www.readbyqxmd.com/read/27986511/anaphylaxis-after-zoster-vaccine-implicating-alpha-gal-allergy-as-a-possible-mechanism
#3
Cosby A Stone, Jonathan A Hemler, Scott P Commins, Alexander J Schuyler, Elizabeth J Phillips, R Stokes Peebles, John M Fahrenholz
No abstract text is available yet for this article.
December 14, 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27878468/the-risk-of-adverse-pregnancy-outcome-after-first-trimester-exposure-to-h1-antihistamines-a-systematic-review-and-meta-analysis
#4
REVIEW
Fatma Etwel, Lauren H Faught, Michael J Rieder, Gideon Koren
INTRODUCTION: H1 antihistamines are used for the treatment of nausea and vomiting during pregnancy as well as the symptomatic relief of asthma, urticaria, allergy, and the common cold. Although they are overall felt to be safe during pregnancy, recently several studies have challenged this assumption, as millions of women are exposed to them in the first trimester. METHODS: Following the guidelines of PRISMA, a systematic review was performed to retrieve all published articles involving H1-antihistamine exposure during pregnancy...
November 22, 2016: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/27650241/allergy-medications-during-pregnancy
#5
REVIEW
Alexei Gonzalez-Estrada, Stephen A Geraci
Allergic diseases are common in women of childbearing age. Both asthma and atopic conditions may worsen, improve or remain the same during pregnancy. Primary care physicians commonly encounter women receiving multiple medications for pre-existing atopic conditions, who then become pregnant and require medication changes to avoid potential fetal injury or congenital malformations. Each medication should be evaluated; intranasal and inhaled steroids are relatively safe to continue during pregnancy (budesonide is the drug of choice), second-generation antihistamines of choice are cetirizine and loratadine, leukotriene receptor antagonists are safe, sparing use of oral decongestants during the first trimester and omalizumab may be used for both uncontrolled asthma and for antihistamine-resistant urticaria...
September 2016: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/26454318/primary-immunodeficiency-masquerading-as-allergic-disease
#6
REVIEW
Sanny K Chan, Erwin W Gelfand
Primary immune deficiencies (PIDs) are an uncommon heterogeneous group of diseases that result from fundamental defects in the proteins and cells that enable specific immune responses. Common allergic reactions (eczema, allergic rhinitis, asthma, and food allergies) are exaggerated immune responses that may be manifestations of an underlying PID. Early diagnosis and treatment has significant bearing on outcome. Immune suppression with systemic corticosteroids in these immune compromised individuals can lead to life threatening dissemination of infections...
November 2015: Immunology and Allergy Clinics of North America
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