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Immunotherapy

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5 papers 0 to 25 followers
https://www.readbyqxmd.com/read/26739402/shellfish-and-house-dust-mite-allergies-is-the-link-tropomyosin
#1
REVIEW
Lydia Wong, Chiung Hui Huang, Bee Wah Lee
Crustacean shellfish allergy is an important cause of food allergy and anaphylaxis in Asia. The major allergen in shellfish allergy is tropomyosin, a pan-allergen that is also found in house dust mites and cockroaches. Tropomyosins from house dust mites (HDMs) have a high sequence homology to shellfish tropomyosins, and cross-reactivity between HDM and shrimp tropomyosins has been demonstrated. Exposure to inhaled tropomyosins from house dust mites has been postulated to be the primary sensitizer for shellfish allergy, in a reaction analogous to the oral allergy (inhalant-food) syndrome...
March 2016: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/27864091/diurnal-variations-in-subcutaneous-allergen-immunotherapy-reactions
#2
Aakash A Bavishi, Leslie C Grammer, Jacqueline Pongracic, Karen Rychlik, Rajesh Kumar, Phyllis Zee, Paul A Greenberger, Anna B Fishbein
BACKGROUND: Circadian rhythms underlie many immune responses and allergic diseases. Subcutaneous immunotherapy (SCIT) can result in adverse reactions; however, it is unclear whether such reactions have a diurnal pattern. OBJECTIVE: To assess whether the timing of SCIT affects the rate of adverse reactions. METHODS: This study was a retrospective medical record review of adult patients (n = 289) who received SCIT at the Northwestern Medical Faculty Foundation, Chicago, Illinois, during a 10-year period (2004-2014)...
November 15, 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27755183/allergen-immunotherapy-for-the-polyallergic-patient
#3
Ulrich Wahn
PURPOSE OF REVIEW: Currently, dramatic changes in allergy treatment can be observed in many countries: The availability of monocomponent products with pharmaceutical quality for sublingual immunotherapy is likely to have a strong impact on all immunotherapy practices and the specialty in general. The market for patient-named products with allergenic mixtures can be expected to shrink. Allergists are concerned about the possibility that single-source products for immunotherapy might be insufficient to serve the needs of all 'polyallergic' patients...
December 2016: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27152601/allergen-immunotherapy-in-polysensitized-patient
#4
REVIEW
M Hrubiško, V Špičák
Specific allergen immunotherapy (AIT) is the only therapeutic method with positive impact on natural course of allergic disease - affecting clinical development (including the progression of rhinitis to asthma) and new sensitisations. The actual problem is the increasing number of patients manifesting poly-sensitivity in allergy skin tests and / or in specific IgE tests. Usually, AIT is not recommended in such individuals. The objective we are facing is that in many patients tested as poly-reactive, we have to distinguish in which cases it is a true polysensitization, and when it is due to cross-reactivity of specific IgE antibodies induced by panallergens...
May 2016: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/26522255/allergen-stabilities-and-compatibilities-in-immunotherapy-mixtures-that-contain-cat-dog-dust-mite-and-cockroach-extracts
#5
Thomas J Grier, Dawn M Hall, Elizabeth A Duncan, Satyen M Gada
BACKGROUND: Indoor allergen mixtures that contain cat, dog, dust mite, and cockroach extracts are commonly used in allergy clinics for subcutaneous immunotherapy, but product-specific stabilities and mixing compatibilities in these complex patient formulas have not been determined. OBJECTIVES: To assess the recoveries of cat, dog epithelia, dog dander, dust mite Dermatophagoides farinae, and cockroach mix allergen activities in 5 component mixtures and 1:10 (vol/vol) dilutions stored for up to 12 months...
December 2015: Annals of Allergy, Asthma & Immunology
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