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Allergic rhinitis

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3 papers 0 to 25 followers
Moisés A Calderón, Jörg Kleine-Tebbe, Allan Linneberg, Frédéric De Blay, Dolores Hernandez Fernandez de Rojas, Johann Christian Virchow, Pascal Demoly
Although house dust mite (HDM) allergy is a major cause of respiratory allergic disease, specific diagnosis and effective treatment both present unresolved challenges. Guidelines for the treatment of allergic rhinitis and asthma are well supported in the literature, but specific evidence on the efficacy of pharmacotherapy treatment for known HDM-allergic patients is weaker. The standard diagnostic techniques--skin prick test and specific IgE testing--can be confounded by cross-reactivity. However, component-resolved diagnosis using purified and recombinant allergens can improve the accuracy of specific IgE testing, but availability is limited...
November 2015: Journal of Allergy and Clinical Immunology in Practice
Geusa Felipa de Barros Bezerra, Denise Maria Costa Haidar, Marcos Antonio Custódio Neto da Silva, Walbert Edson Muniz Filho, Ramon Moura Dos Santos, Ivone Garros Rosa, Graça Maria de Castro Viana, Luís Zaror, Maria do Desterro Soares Brandão Nascimento
BACKGROUND: To evaluate total and specific E immunoglobulin (IgE) antibody concentrations in underage subjects with respiratory allergic diseases. METHODS: This study was a transversal-type study in 100 underage subjects between 4 and 14 years old, with asthma and/or allergic rhinitis. Total and specific IgE were quantified for airborne fungi in the city of São Luís, Maranhão, Brazil. Five distinct regions-North, South, Center, East and West-were selected so fungi could be collected monthly for 1 year...
2016: Allergy, Asthma, and Clinical Immunology
Xue Yan Wang, Margaret Lim-Jurado, Narayanan Prepageran, Pongsakorn Tantilipikorn, De Yun Wang
Allergic rhinitis and urticaria are common allergic diseases that may have a major negative impact on patients' quality of life. Bilastine, a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action. This agent does not interact with the cytochrome P450 system and does not undergo significant metabolism in humans, suggesting that it has very low potential for drug-drug interactions, and does not require dose adjustment in renal impairment...
2016: Therapeutics and Clinical Risk Management
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