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Food allergy

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101 papers 25 to 100 followers
https://www.readbyqxmd.com/read/29117431/food-allergy-and-atopic-dermatitis-prediction-progression-and-prevention
#1
REVIEW
Carla Mastrorilli, Carlo Caffarelli, Karin Hoffmann-Sommergruber
The rising burden of allergic diseases in childhood requires a compelling need to identify individuals at risk for atopy very early in life or even predict the onset of food allergy and atopic dermatitis since pregnancy. The development and clinical phenotypes of atopic diseases in childhood depends on a complex interaction between genetic and environmental factors, such as allergen exposure, air pollution and infections. Preventive strategies may include avoidance measures, diet supplements and early complementary food introduction...
November 8, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29097103/the-allergen-specificity-of-early-peanut-consumption-and-the-impact-on-the-development-of-allergic-disease-in-the-leap-study-cohort
#2
George du Toit, Peter H Sayre, Graham Roberts, Kaitie Lawson, Michelle L Sever, Henry T Bahnson, Helen R Fisher, Mary Feeney, Suzana Radulovic, Monica Basting, Marshall Plaut, Gideon Lack
BACKGROUND: Early introduction of dietary peanut in high-risk infants with severe eczema and/or egg allergy prevented peanut allergy at 5 years of age in the LEAP Study; the protective effect persisted after 12 months of avoiding peanuts in the LEAP-On Study. It is unclear whether this benefit is allergen and allergic-disease specific. OBJECTIVE: To assess the impact of early introduction of peanut on the development of allergic disease, food sensitization and aeroallergen sensitization...
October 30, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29025431/specific-ige-and-skin-prick-tests-to-diagnose-allergy-to-fresh-and-baked-cow-s-milk-according-to-age-a-systematic-review
#3
REVIEW
Barbara Cuomo, Giovanni Cosimo Indirli, Annamaria Bianchi, Stefania Arasi, Davide Caimmi, Arianna Dondi, Stefania La Grutta, Valentina Panetta, Maria Carmen Verga, Mauro Calvani
BACKGROUND: The diagnosis of IgE-mediated cow's milk allergy is often based on anamnesis, and on specific IgE (sIgE) levels and/or Skin Prick Tests (SPT), which have both a good sensitivity but a low specificity, often causing positive results in non-allergic subjects. Thus, oral food challenge is still the gold standard test for diagnosis, though being expensive, time-consuming and possibly at risk for severe allergic reactions. AIM: The aim of the present study was to perform a systematic review of the studies that have so far analyzed the positive predictive values for sIgE and SPT in the diagnosis of allergy to fresh and baked cow's milk according to age, and to identify possible cut-offs that may be useful in clinical practice...
October 12, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28944625/allergy-to-peanut-soybean-and-other-legumes-recent-advances-in-allergen-characterization-stability-to-processing-and-ige-cross-reactivity
#4
REVIEW
Beatriz Cabanillas, Uta Jappe, Natalija Novak
Peanut and soybean are members of the Leguminosae family. They are two of the eight foods that account for the most significant food allergies in the US and Europe. Allergic reactions to other legume species can be of importance in other regions of the world. The major allergens from peanut and soybean have been extensively analyzed and members of new protein families identified as potential marker allergens for symptom severity. Important recent advances concerning their molecular properties or clinical relevance have been made...
September 25, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28890356/multicenter-prevalence-of-anaphylaxis-in-clinic-based-oral-food-challenges
#5
MULTICENTER STUDY
Kwei Akuete, Danielle Guffey, Ryan B Israelsen, John M Broyles, Lori Jo Higgins, Todd D Green, David R Naimi, Andrew J MacGinnitie, Girish Vitalpur, Charles G Minard, Carla M Davis
BACKGROUND: Although previous single-center studies report the rate of anaphylaxis for oral food challenges (OFCs) as 9% to 11%, little is known regarding the epidemiology of clinical OFCs across multiple centers in the United States. OBJECTIVE: To examine the epidemiology, symptoms, and treatment of clinical low-risk OFCs in the nonresearch setting. METHODS: Data were obtained from 2008 to 2013 through a physician survey in 5 food allergy centers geographically distributed across the United States...
October 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28947906/oral-food-challenge-outcomes-in-a-pediatric-tertiary-care-center
#6
Elissa M Abrams, Allan B Becker
BACKGROUND: Oral food challenges are the clinical standard for diagnosis of food allergy. Little data exist on predictors of oral challenge failure and reaction severity. METHODS: A retrospective chart review was done on all pediatric patients who had oral food challenges in a tertiary care pediatric allergy clinic from 2008 to 2010. RESULTS: 313 oral challenges were performed, of which the majority were to peanut (105), egg (71), milk (41) and tree nuts (29)...
2017: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/28836701/bsaci-guideline-for-the-diagnosis-and-management-of-peanut-and-tree-nut-allergy
#7
G Stiefel, K Anagnostou, R J Boyle, N Brathwaite, P Ewan, A T Fox, P Huber, D Luyt, S J Till, C Venter, A T Clark
Peanut nut and tree nut allergy are characterised by IgE mediated reactions to nut proteins. Nut allergy is a global disease. Limited epidemiological data suggest varying prevalence in different geographical areas. Primary nut allergy affects over 2% of children and 0.5% of adults in the UK. Infants with severe eczema and/or egg allergy have a higher risk of peanut allergy. Primary nut allergy presents most commonly in the first five years of life, often after the first known ingestion with typical rapid onset IgE-mediated symptoms...
June 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28986924/physician-s-appraisal-versus-documented-signs-and-symptoms-in-the-interpretation-of-food-challenge-tests-the-europrevall-birth-cohort
#8
Linus B Grabenhenrich, Andreas Reich, Doreen McBride, Aline Sprikkelman, Graham Roberts, Kate E C Grimshaw, Alessandro G Fiocchi, Photini Saxoni-Papageorgiou, Nikolaos G Papadopoulos, Ana Fiandor, Santiago Quirce, Marek L Kowalski, Sigurveig T Sigurdardottir, Ruta Dubakiene, Jonathan O B Hourihane, Leonard Rosenfeld, Bodo Niggemann, Thomas Keil, Kirsten Beyer
BACKGROUND: Blinded food challenges are considered the current gold standard for the diagnosis of food allergies. We used data from a pan-European multicentre project to assess differences between study centres, aiming to identify the impact of subjective aspects for the interpretation of oral food challenges. METHODS: Nine study centres of the EuroPrevall birth cohort study on food allergy recruited 12,049 newborns and followed them for up to 30 months in regular intervals...
October 6, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28743426/sesame-allergy-in-adults-investigation-and-outcomes-of-oral-food-challenges
#9
Philip H Li, Natasha Gunawardana, Iason Thomas, Kok Loong Ue, Leonard Siew, Timothy J Watts, Keyna Bintcliffe, Rubaiyat Haque, Krzysztof Rutkowski, Isabel Skypala, Stephen J Till
No abstract text is available yet for this article.
September 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28847653/a-three-level-stepwise-oral-food-challenge-for-egg-milk-and-wheat-allergy
#10
Noriyuki Yanagida, Takanori Minoura, Setsuko Kitaoka, Motohiro Ebisawa
No abstract text is available yet for this article.
August 25, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28779526/the-role-of-environmental-exposure-to-peanut-in-the-development-of-clinical-allergy-to-peanut
#11
REVIEW
R X Foong, H Brough
The prevalence of peanut allergy has increased over the years and still remains one of the most common causes of food-related anaphylaxis. The way in which peanut sensitization occurs has been explored, such as via maternal consumption in pregnancy, via breastmilk and through a disrupted skin barrier. It has previously been shown that environmental exposure to aeroallergens in household dust can be a risk factor for the development of allergic asthma. There is an increasing body of evidence that the combination of cutaneous sensitization via a disrupted skin barrier (ie children with eczema or with filaggrin mutations) and environmental peanut exposure influences the development of peanut allergy...
October 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28739336/oral-tolerance-and-allergy
#12
REVIEW
Ahmad Hamad, Wesley Burks
Food allergy prevalence is increasing in the developed world. It's estimated that each year in the US, anaphylaxis to food results in 30,000 emergency room visits and 150 deaths. Over the past few decades, there has been a tremendous effort to better understand the pathogenesis of food allergy and mechanisms of food tolerance. In this article we review the structural of the gastrointestinal immune system and mechanisms of natural tolerance to food. We then review the factors that may result in the IgE mediated hypersensitivity reaction to food allergens resulting in clinical food allergy...
April 2017: Seminars in Immunology
https://www.readbyqxmd.com/read/28757143/methods-in-allergy-immunology-food-challenges
#13
EDITORIAL
Barbara K Ballmer-Weber, Kirsten Beyer
Since there is no in vitro test, which can accurately predict the clinical relevance of a sensitization to food, the oral food challenge still remains the most reliable procedure to confirm or exclude food allergy and to assess the development of tolerance in children with potentially transient food allergies such as to cow's milk, hen's egg, wheat or soy. Although in the last few years component-resolved diagnostic has improved the food allergy diagnostics, especially in peanut and tree nut allergy, the majority of patients still need to undergo oral food challenge...
July 27, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28649294/randomised-controlled-trial-of-a-baked-egg-intervention-in-young-children-allergic-to-raw-egg-but-not-baked-egg
#14
Merryn Netting, Michael Gold, Patrick Quinn, Adaweyah El-Merhibi, Irmeli Penttila, Maria Makrides
BACKGROUND: Consumption of baked egg by raw egg allergic children is associated with immune changes suggesting development of tolerance. However, causation has not been tested using a double blind randomized controlled trial (RCT). We aimed to compare clinical and immunological outcomes after baked egg (BE) consumption in young BE tolerant egg allergic children. METHODS: In a double blind RCT, BE tolerant egg allergic children consumed 10 g BE (1.3 g protein) 2 to 3 times per week for 6 months (n = 21 intervention group) or similar egg free baked goods (n = 22 control group) while maintaining an otherwise egg free diet...
2017: World Allergy Organization Journal
https://www.readbyqxmd.com/read/28676231/oral-immunotherapy-for-food-allergy-a-spanish-guideline-egg-and-milk-immunotherapy-spanish-guide-items-guide-part-2-maintenance-phase-of-cow-milk-cm-and-egg-oral-immunotherapy-oit-special-treatment-dosing-schedules-models-of-dosing-schedules-of-oit-with-cm
#15
REVIEW
A Martorell, E Alonso, L Echeverría, C Escudero, R García-Rodríguez, C Blasco, J Bone, J Borja-Segade, T Bracamonte, A Claver, J L Corzo, B De la Hoz, R Del Olmo, O Dominguez, V Fuentes-Aparicio, I Guallar, H Larramona, F Martín-Muñoz, V Matheu, A Michavila, I Ojeda, P Ojeda, M Piquer, P Poza, M Reche, P Rodríguez Del Río, M Rodríguez, F Ruano, S Sánchez-García, S Terrados, L Valdesoiro, M Vazquez-Ortiz
INTRODUCTION: Cow's milk and egg are the most frequent causes of food allergy in the first years of life. Treatments such as oral immunotherapy (OIT) have been investigated as an alternative to avoidance diets. No clinical practice guides on the management of OIT with milk and egg are currently available. OBJECTIVES: To develop a clinical guide on OIT based on the available scientific evidence and the opinions of experts. METHODS: A review was made of studies published in the period between 1984 and June 2016, Doctoral Theses published in Spain, and summaries of communications at congresses (SEAIC, SEICAP, EAACI, AAAAI), with evaluation of the opinion consensus established by a group of experts pertaining to the scientific societies SEICAP and SEAIC...
September 2017: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/28634899/primary-prevention-of-food-allergy
#16
REVIEW
Rachel L Peters, Melanie R Neeland, Katrina J Allen
PURPOSE OF REVIEW: This article summarises recent developments on the prevention of food allergy in terms of the 5 D's of the development of food allergy: dry skin, diet, dogs, dribble, and vitamin D. RECENT FINDINGS: While several advances have improved our understanding of the development of food allergy, few preventive strategies have been implemented beyond changes in infant feeding guidelines. These now state that the introduction of allergenic solids such as peanuts should occur in the first year of life...
August 2017: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/28516451/evidence-that-eating-baked-egg-or-milk-influences-egg-or-milk-allergy-resolution-a-systematic-review
#17
REVIEW
R Lambert, K E C Grimshaw, B Ellis, J Jaitly, G Roberts
BACKGROUND: It has been proposed that the frequent ingestion of baked hen's egg or cow's milk accelerates the resolution of hen's egg or cow's milk allergy. This practice is being introduced into clinical practice. OBJECTIVE: To systematically review the evidence to determine whether the introduction of baked hen's egg or cow's milk into the diet of children with hen's egg or cow's milk allergies respectively leads to a larger proportion of children outgrowing these allergies than expected...
June 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28601052/evaluation-of-food-allergy-in-children-by-skin-prick-tests-with-commercial-extracts-and-fresh-foods-specific-ige-and-open-oral-food-challenge-our-five-years-experience-in-food-allergy-work-up
#18
Mirjana Zivanovic, Marina Atanasković-Marković, Biljana Medjo, Marija Gavrović-Jankulović, Katarina Smiljanić, Vladimir Tmušić, Vojislav Djurić
IgE- mediated food allergy affects 6-8% of children. Our study aimed to define the correlations between the results obtained with skin prick tests (SPTs) using commercial extracts and fresh foods, and the correlations between these result and those obtained with specific IgE (sIgE) and/ or challenge. Children aged from 2 months to 6 years were recruited prospectively. Overall 571 children were positive to one food. In all children we performed  SPT using commercial extracts of suspected food and fresh foods and sIgE...
April 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/28416249/prognostic-accuracy-of-clinical-signs-and-diagnostic-tests-in-cow-s-milk-allergy-in-newborns
#19
Gregor Nosan, Maja Jakic, Miha Jager, Darja Paro-Panjan
BACKGROUND: The aim of the study was to explore the correlation between clinical signs and confirmatory tests for cow's milk allergy (CMA) in the neonatal period and their relation to family history and the occurrence of food allergies in the postneonatal period. METHODS: The medical documentation of 361 newborns with suspected CMA and exclusion of other comorbidities was analyzed. The correlations between clinical signs and methods to confirm CMA [elevated levels of total immunoglobulin E (IgE) and/or specific IgE for cow's milk, improvement after the introduction of a cow's milk-free diet and positive challenge procedure] were studied...
March 27, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/27613460/prevalence-of-fish-and-shellfish-allergy-a-systematic-review
#20
REVIEW
Harriet Moonesinghe, Heather Mackenzie, Carina Venter, Sally Kilburn, Paul Turner, Kellyn Weir, Taraneh Dean
BACKGROUND: Accurate information on the prevalence of food allergy facilitates a more evidence-based approach to planning of allergy services and can identify important geographic variations. OBJECTIVE: To conduct a systematic review to assess the age-specific prevalence of fish and shellfish allergy worldwide. METHODS: Searches were conducted using Web of Science and PubMed. Population-based cross-sectional studies and cohort studies that examined the prevalence of fish and shellfish allergy (IgE mediated and non-IgE mediated) at an identifiable point in time were eligible for inclusion in the study...
September 2016: Annals of Allergy, Asthma & Immunology
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