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Susan Leslie Clinic for Neuroendocrine Tumours

https://read.qxmd.com/read/12831921/surgical-treatment-of-neuroendocrine-metastases-to-the-liver-a-plea-for-resection-to-increase-survival
#21
JOURNAL ARTICLE
Juan M Sarmiento, Glenroy Heywood, Joseph Rubin, Duane M Ilstrup, David M Nagorney, Florencia G Que
BACKGROUND: Hepatic metastases from neuroendocrine tumors have a protracted natural history and are associated with endocrinopathies. Resection is indicated for symptom control. Previous reports have suggested improvement in survival for patients undergoing debulking procedures. STUDY DESIGN: The records of all consecutive patients undergoing resection of hepatic metastases from neuroendocrine tumors between 1977 and 1998 were reviewed. Tumors were classified according to histology, endocrine activity, and primary location...
July 2003: Journal of the American College of Surgeons
https://read.qxmd.com/read/12717354/liver-resection-and-associated-extrahepatic-resections-for-metastatic-well-differentiated-endocrine-tumors-a-15-year-single-center-prospective-study
#22
JOURNAL ARTICLE
Dominique Elias, Philippe Lasser, Michel Ducreux, Pierre Duvillard, Jean-Francois Ouellet, Clarice Dromain, Martin Schlumberger, Marc Pocard, Valérie Boige, Catherine Miquel, Eric Baudin
BACKGROUND: The timing and benefits of hepatectomy remain controversial for metastatic well-differentiated endocrine neoplasms, which are generally considered slow growth tumors. However, surveillance alone yields only a 22% 5-year survival when metastases occur. The aim of this study was to determine the results of hepatic and extra hepatic resections and to clarify the indications of surgery. METHODS: To define the role of hepatic resection, a database regrouping all patients (n = 47) who underwent hepatectomy with curative intent (R0 status) for well-differentiated endocrine neoplasms in the Gustave-Roussy Institute was constructed in 1984...
April 2003: Surgery
https://read.qxmd.com/read/12016480/effect-of-surgery-on-the-outcome-of-midgut-carcinoid-disease-with-lymph-node-and-liver-metastases
#23
JOURNAL ARTICLE
Per Hellman, Tobias Lundström, Ulf Ohrvall, Barbro Eriksson, Britt Skogseid, Kjell Oberg, Eva Tiensuu Janson, Göran Akerström
We have evaluated survival and tumor-related symptoms in the presence of mesenteric lymph node and liver metastases in relation to surgical procedures in 314 patients (148 women, mean age at diagnosis 61 years; 249 with liver metastases) treated for midgut carcinoid tumors. Of the operated patients, 46% presented with severe abdominal pain and intestinal obstruction and were operated on before the diagnosis. Medical treatment (somatostatin analogs, interferon-a) was initiated in 67% and 86%, respectively. Surgical attempts included small intestine or ileocecal/right-sided colon resection with excision of mesenteric lymph node metastases...
August 2002: World Journal of Surgery
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