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Palliative

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By Saadvik Raghuram Mbbs graduate, persuing radiation oncology
https://www.readbyqxmd.com/read/27604504/dexamethasone-and-supportive-care-with-or-without-whole-brain-radiotherapy-in-treating-patients-with-non-small-cell-lung-cancer-with-brain-metastases-unsuitable-for-resection-or-stereotactic-radiotherapy-quartz-results-from-a-phase-3-non-inferiority-randomised
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Paula Mulvenna, Matthew Nankivell, Rachael Barton, Corinne Faivre-Finn, Paula Wilson, Elaine McColl, Barbara Moore, Iona Brisbane, David Ardron, Tanya Holt, Sally Morgan, Caroline Lee, Kathryn Waite, Neil Bayman, Cheryl Pugh, Benjamin Sydes, Richard Stephens, Mahesh K Parmar, Ruth E Langley
BACKGROUND: Whole brain radiotherapy (WBRT) and dexamethasone are widely used to treat brain metastases from non-small cell lung cancer (NSCLC), although there have been no randomised clinical trials showing that WBRT improves either quality of life or overall survival. Even after treatment with WBRT, the prognosis of this patient group is poor. We aimed to establish whether WBRT could be omitted without a significant effect on survival or quality of life. METHODS: The Quality of Life after Treatment for Brain Metastases (QUARTZ) study is a non-inferiority, phase 3 randomised trial done at 69 UK and three Australian centres...
October 22, 2016: Lancet
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