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Lidocaine lignocaine infusion surgery

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33 papers 0 to 25 followers Lidocaine Lignocaine intravenous infusion in surgery papers
Geertrui Barbara Erika Dewinter, An Teunkens, Kristien Vermeulen, Layth Al Tmimi, Marc Van de Velde, Steffen Rex
BACKGROUND AND OBJECTIVES: Perioperative systemic lidocaine provides postoperative analgesia, decreases opioid consumption, and facilitates rehabilitation in abdominal surgery. We hypothesized that systemic lidocaine has analgesic effects in women undergoing day-case laparoscopic sterilization. METHODS: Eighty women were randomized in this prospective, double-blind trial to receive either lidocaine (intravenous bolus of 1.5 mg/kg at induction of anesthesia, followed by an infusion of 1...
May 2016: Regional Anesthesia and Pain Medicine
Yuan-Ching Chang, Chien-Liang Liu, Tsang-Pai Liu, Po-Sheng Yang, Ming-Jen Chen, Shih-Ping Cheng
OBJECTIVES: Intravenous lidocaine infusion has been shown to reduce postoperative pain among patients undergoing abdominal surgery. This study aimed to evaluate the effects of perioperative lidocaine administration in breast surgery. METHODS: A meta-analysis of randomized controlled trials comparing lidocaine infusion vs. placebo/routine treatment was performed. Standardized mean difference (SMD) or risk ratio (RR) with 95% confidence intervals (CIs) was calculated from pooled data...
February 23, 2016: Pain Practice: the Official Journal of World Institute of Pain
Jeffrey A Klein, Daniel R Jeske
BACKGROUND: Tumescent lidocaine anesthesia consists of subcutaneous injection of relatively large volumes (up to 4 L or more) of dilute lidocaine (≤1 g/L) and epinephrine (≤1 mg/L). Although tumescent lidocaine anesthesia is used for an increasing variety of surgical procedures, the maximum safe dosage is unknown. Our primary aim in this study was to measure serum lidocaine concentrations after subcutaneous administration of tumescent lidocaine with and without liposuction. Our hypotheses were that even with large doses (i...
May 2016: Anesthesia and Analgesia
Abdullah S Terkawi, Siny Tsang, Ali Kazemi, Steve Morton, Roy Luo, Daniel T Sanders, Lindsay A Regali, Heather Columbano, Nicole Y Kurtzeborn, Marcel E Durieux
BACKGROUND: Epidural analgesia provides good pain control after many postoperative procedures, but it can lead to complications, has some contraindications, and occasionally fails. Intravenous lidocaine infusion has been suggested as an alternative. We assessed, in our clinical practice, the effects of perioperative intravenous lidocaine infusion compared with epidural analgesia for major abdominal surgery. METHODS: We conducted a retrospective review of patients who had received intravenous lidocaine (1 mg/kg per hour) perioperatively after a major abdominal surgery...
January 2016: Regional Anesthesia and Pain Medicine
James S Khan, Maaz Yousuf, J Charles Victor, Abhinav Sharma, Naveed Siddiqui
STUDY OBJECTIVE: There exists no commonly accepted regimen for an intravenous lidocaine infusion (IVLI). This study aims to determine an appropriate end time for an IVLI during bowel surgery. DESIGN: A systematic search for randomized controlled trials assessing IVLI for bowel surgery was conducted using Ovid MEDLINE, EMBASE, CINAHL, Cochrane CENTRAL, Google Scholar, hand-searching references, and grey literature. Data were pooled for studies that stopped IVLI ≤60 minutes (intraoperative IVLI) after skin closure and where IVLI continued >60 minutes after surgery (postoperative continued IVLI)...
February 2016: Journal of Clinical Anesthesia
Patrick J Bafuma, Arun Nandi, Michael Weisberg
A 24-year-old female patient presented to our community emergency department (ED) for abdominal pain that had progressively worsened over the last 28 hours. Of note, 1 month prior to her presentation, the patient had a colostomy due to a rectal abscess and required stoma revision 5 days prior to her visit to our ED. The patient's pain was refractory to opiate analgesia in our ED, but experienced significant relief after an intravenous lidocaine infusion. Computer tomography of the abdomen and pelvis ultimately revealed a large bowel obstruction just proximal to the colostomy site...
October 2015: American Journal of Emergency Medicine
Shruti Jain, Rashid M Khan
BACKGROUND AND AIMS: Lignocaine in intravenous (IV) bolus dose has been used for minimising haemodynamic changes associated with intubation and extubation. Furthermore, IV infusion has been used for post-operative analgesia. We investigated whether IV peri-operative lignocaine (bolus and infusion) would be able to produce both the effects simultaneously in elective laparoscopic cholecystectomies. METHODS: In this randomised prospective study, 60 patients undergoing elective laparoscopic cholecystectomy were randomly divided into two groups of 30 each...
June 2015: Indian Journal of Anaesthesia
Peter Kranke, Johanna Jokinen, Nathan Leon Pace, Alexander Schnabel, Markus W Hollmann, Klaus Hahnenkamp, Leopold H J Eberhart, Daniel M Poepping, Stephanie Weibel
BACKGROUND: The management of postoperative pain and recovery is still unsatisfactory in clinical practice. Opioids used for postoperative analgesia are frequently associated with adverse effects including nausea and constipation. These adverse effects prevent smooth postoperative recovery. On the other hand not all patients may be suited to, and take benefit from, epidural analgesia used to enhance postoperative recovery. The non-opioid lidocaine was investigated in several studies for its use in multi-modal management strategies to reduce postoperative pain and enhance recovery...
July 16, 2015: Cochrane Database of Systematic Reviews
Seniyye Ulgen Zengin, Ayten Saracoglu, Zeynep Eti, Tumay Umuroglu, Fevzi Yilmaz Gogus
OBJECTIVES: To evaluate and compare the effects of preoperative oral pregabalin and perioperative intravenous lidocaine infusion on postoperative morphine requirement, adverse effects, patients' satisfaction, mobilization, time to first defecation and time to discharge in patients undergoing laparotomy. METHODS: Eighty patients (18 to 65 years of age) undergoing elective laparotomy were randomly divided into four groups (n=20 in each group): group C, placebo capsules and normal saline infusion perioperatively (control); group L, placebo capsules and lidocaine 1 mg⁄kg intravenous bolus dose followed by 2 mg⁄kg⁄h infusion until skin closure; group P, 150 mg oral pregabalin and normal saline infusion perioperatively; and group PL, 150 mg oral pregabalin and lidocaine 2 mg⁄kg⁄h infusion until skin closure...
July 2015: Pain Research & Management: the Journal of the Canadian Pain Society
Abdullah S Terkawi, Sonal Sharma, Marcel E Durieux, Swapna Thammishetti, David Brenin, Mohamed Tiouririne
BACKGROUND: Chronic post-surgical pain (CPSP) is a not uncommon complication after mastectomy, with a reported incidence between 20% and 68%. Careful dissection, the use of minimally invasive surgical techniques, and attempts to reduce the associated inflammatory and hyperalgesic responses are suggested methods to prevent CPSP. OBJECTIVE: To determine if the use of perioperative lidocaine infusion is associated with decreased incidence of CPSP after mastectomy. STUDY DESIGN: Double-blind, placebo-controlled randomized trial...
March 2015: Pain Physician
EunJin Ahn, Hyun Kang, Geun Joo Choi, Yong Hee Park, So Young Yang, Beom Gyu Kim, Seung Won Choi
A perioperative intravenous lidocaine infusion has been reported to decrease postoperative pain. The goal of this study was to evaluate the effectiveness of intravenous lidocaine in reducing postoperative pain for laparoscopic colectomy patients. Fifty-five patients scheduled for an elective laparoscopic colectomy were randomly assigned to 2 groups. Group L received an intravenous bolus injection of lidocaine 1.5 mg/kg before intubation, followed by 2 mg/kg/h continuous infusion during the operation. Group C received the same dosage of saline at the same time...
March 2015: International Surgery
Abdullah S Terkawi, Marcel E Durieux, Antje Gottschalk, David Brenin, Mohamed Tiouririne
BACKGROUND: One of the modalities of treatment for breast cancer surgery pain is opioids, and opioids are associated with adverse effects such as itching and postoperative nausea and vomiting (PONV). Intravenous (IV) lidocaine has been shown to reduce opioid consumption and to improve overall postoperative outcomes in abdominal surgery. In this study, we tested the effect of intraoperative IV lidocaine infusion on the quality of postoperative recovery after breast cancer surgery. METHODS: Seventy-one patients undergoing breast cancer surgery were randomly assigned to receive either placebo (group P; n = 34) or IV lidocaine (group L; n = 37, bolus 1...
November 2014: Regional Anesthesia and Pain Medicine
Chryssoula Staikou, Alexandra Avramidou, Georgios D Ayiomamitis, Spyros Vrakas, Eriphili Argyra
BACKGROUND: We compared the effects of intravenous lidocaine (IVL) with lumbar epidural lidocaine analgesia (LEA) on pain and ileus after open colonic surgery. METHODS: Between December 2011 and February 2013, 60 patients were randomly allocated to IVL, LEA, or control group. The IVL group received intraoperatively lidocaine 2 % intravenously (1.5 mg/kg bolus, 2 mg/kg/h infusion) and normal saline (NS) epidurally. The LEA group received lidocaine epidurally (1.5 mg/kg bolus, 2 mg/kg/h infusion) and NS intravenously...
December 2014: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
Parnandi Sridhar, Sarath Chandra Sistla, Sheik Manwar Ali, Vilvapathy Senguttuvan Karthikeyan, Ashok Shankar Badhe, Palghat Hariharan Ananthanarayanan
BACKGROUND: Perioperative stress response can be detrimental if excessive and prolonged. Intravenous (i.v.) lignocaine, while being an effective analgesic, has the added benefit of anti-inflammatory activity. This study was done to assess the effect of i.v. lignocaine on operative stress response and post-surgical ileus after elective open abdominal surgeries. METHODS: Patients (n = 134) were randomized into two groups (n = 67 each) to receive an i.v. infusion of lignocaine (group L) or saline (group S) as a bolus of 1...
June 2015: ANZ Journal of Surgery
So Young Yang, Hyun Kang, Geun Joo Choi, Hwa Yong Shin, Chong Wha Baek, Yong Hun Jung, Yoo Shin Choi
OBJECTIVES: This randomized, double-blind, placebo-controlled trial evaluated intraperitoneal (IP) lidocaine administration and intravenous (IV) lidocaine infusion for postoperative pain control after laparoscopic cholecystectomy (LC). METHODS: Patients who underwent LC were randomized to either group IV (intravenous lidocaine infusion), group IP (intraperitoneal lidocaine administration), or group C (control, IP and IV saline). Outcome measures were total postoperative pain severity (TPPS), total fentanyl consumption (TFC), frequency of administering patient-controlled analgesia (FPB), and a pain control satisfaction score (PCSS)...
April 2014: Journal of International Medical Research
Kyoung-Tae Kim, Dae-Chul Cho, Joo-Kyung Sung, Young-Baeg Kim, Hyun Kang, Kwang-Sup Song, Geun-Joo Choi
BACKGROUND CONTEXT: Analgesic effect of lidocaine infusion on postoperative pain. PURPOSE: The aim of this study was to evaluate the analgesic effect of lidocaine infusion on postoperative pain after lumbar microdiscectomy. STUDY DESIGN: This study used a prospective, randomized, double-blinded, and placebo-controlled clinical trial. PATIENT SAMPLE: Fifty-one patients participated in this randomized, double-blinded study...
August 1, 2014: Spine Journal: Official Journal of the North American Spine Society
Gildasio S De Oliveira, Kenyon Duncan, Paul Fitzgerald, Antoun Nader, Robert W Gould, Robert J McCarthy
BACKGROUND: Few multimodal strategies to minimize postoperative pain and improve recovery have been examined in morbidly obese patients undergoing laparoscopic bariatric surgery. The main objective of this study was to evaluate the effect of systemic intraoperative lidocaine on postoperative quality of recovery when compared to saline. METHODS: The study was a prospective randomized, double-blinded placebo-controlled clinical trial. Subjects undergoing laparoscopic bariatric surgery were randomized to receive lidocaine (1...
February 2014: Obesity Surgery
R Tikuišis, P Miliauskas, N E Samalavičius, A Žurauskas, R Samalavičius, V Zabulis
BACKGROUND: Perioperative intravenous (IV) infusion of lidocaine has been shown to decrease post-operative pain, shorten time to return of bowel function, and reduce the length of hospital stay. This randomized, prospective, double-blinded, placebo-controlled clinical trial evaluated the impact of IV lidocaine on the quality of post-operative analgesia and other outcomes after hand-assisted laparoscopic colon surgery. METHODS: Sixty four patients with colon cancer scheduled for elective colon resection were involved in this study...
April 2014: Techniques in Coloproctology
Tod B Sloan, Paul Mongan, Clark Lyda, Antoun Koht
Total intravenous anesthesia (TIVA) with propofol and opioids is frequently utilized for spinal surgery where somatosensory evoked potentials (SSEP) and motor evoked potentials (tcMEP) are monitored. Lidocaine infusions can contribute to antinociception and unconsciousness, thus allowing for a reduction in the total dose of propofol. We examined our recent experience with lidocaine infusions to quantify this effect. After institutional review board approval, we conducted a retrospective review of propofol usage in propofol-opioid TIVA (with and without lidocaine) for spine cases monitored with SSEP and tcMEP over a 7 months period...
April 2014: Journal of Clinical Monitoring and Computing
Ehab Farag, Michael Ghobrial, Daniel I Sessler, Jarrod E Dalton, Jinbo Liu, Jae H Lee, Sherif Zaky, Edward Benzel, William Bingaman, Andrea Kurz
BACKGROUND: The authors tested the primary hypothesis that perioperative IV lidocaine administration during spine surgery (and in the postanesthesia care unit for no more than 8 h) decreases pain and/or opioid requirements in the initial 48 postoperative hours. Secondary outcomes included major complications, postoperative nausea and vomiting, duration of hospitalization, and quality of life. METHODS: One hundred sixteen adults having complex spine surgery were randomly assigned to perioperative IV lidocaine (2 mg·kg·h) or placebo during surgery and in the postanesthesia care unit...
October 2013: Anesthesiology
2016-09-15 10:03:38
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