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Alzheimer and Keto

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https://www.readbyqxmd.com/read/26766547/can-ketones-compensate-for-deteriorating-brain-glucose-uptake-during-aging-implications-for-the-risk-and-treatment-of-alzheimer-s-disease
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Stephen C Cunnane, Alexandre Courchesne-Loyer, Valérie St-Pierre, Camille Vandenberghe, Tyler Pierotti, Mélanie Fortier, Etienne Croteau, Christian-Alexandre Castellano
Brain glucose uptake is impaired in Alzheimer's disease (AD). A key question is whether cognitive decline can be delayed if this brain energy defect is at least partly corrected or bypassed early in the disease. The principal ketones (also called ketone bodies), β-hydroxybutyrate and acetoacetate, are the brain's main physiological alternative fuel to glucose. Three studies in mild-to-moderate AD have shown that, unlike with glucose, brain ketone uptake is not different from that in healthy age-matched controls...
March 2016: Annals of the New York Academy of Sciences
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