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77 papers 25 to 100 followers
https://www.readbyqxmd.com/read/27865536/breast-cancer
#1
REVIEW
Nadia Harbeck, Michael Gnant
Breast cancer is one of the three most common cancers worldwide. Early breast cancer is considered potentially curable. Therapy has progressed substantially over the past years with a reduction in therapy intensity, both for locoregional and systemic therapy; avoiding overtreatment but also undertreatment has become a major focus. Therapy concepts follow a curative intent and need to be decided in a multidisciplinary setting, taking molecular subtype and locoregional tumour load into account. Primary conventional surgery is not the optimal choice for all patients any more...
November 16, 2016: Lancet
https://www.readbyqxmd.com/read/27892919/practice-bulletin-no-165-summary-prevention-and-management-of-obstetric-lacerations-at-vaginal-delivery-correction
#2
(no author information available yet)
No abstract text is available yet for this article.
August 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27885797/postpartum-haemorrhage-a-single-definition-is-no-longer-enough
#3
R S Kerr, A D Weeks
No abstract text is available yet for this article.
November 24, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27875472/practice-bulletin-no-175-ultrasound-in-pregnancy
#4
(no author information available yet)
No abstract text is available yet for this article.
December 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27840142/evaluation-of-normalizing-cerebroplacental-ratio-as-a-potential-predictor-for-adverse-outcome-in-intrauterine-growth-restriction-results-of-the-multicenter-prospective-observational-trial-to-optimize-pediatric-health-in-intrauterine-growth-restriction-porto
#5
Cathy Monteith, Karen Flood, Sieglinde Mullers, Julia Unterscheider, Fionnuala Breathnach, Sean Daly, Michael P Geary, Mairead M Kennelly, Fionnuala M McAuliffe, Keelin O'Donoghue, Alison Hunter, John J Morrison, Gerald Burke, Patrick Dicker, Elizabeth C Tully, Fergal D Malone
BACKGROUND: Intrauterine growth restriction accounts for a significant proportion of perinatal morbidity and mortality currently encountered in obstetric practice. The primary goal of antenatal care is the early recognition of such conditions to allow treatment and optimization of both maternal and fetal outcomes. Management of pregnancies complicated by intrauterine growth restriction remains one of the greatest challenges in obstetrics. Frequently, however, clinical evidence of underlying uteroplacental dysfunction may only emerge at a late stage in the disease process...
November 11, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27865945/episiotomy-in-vacuum-assisted-delivery-affects-the-risk-of-obstetric-anal-sphincter-injury-a-systematic-review-and-meta-analysis
#6
REVIEW
Ninna S Lund, Lisa K G Persson, Hanna Jangö, Ditte Gommesen, Hanne B Westergaard
The risk of obstetric anal sphincter injury (OASIS) is increased in vacuum-assisted delivery. However, it remains unclear whether episiotomy may protect against OASIS in this type of delivery. The objective of this study was to assess whether mediolateral or lateral episiotomy affects the risk of OASIS in vacuum-assisted delivery among primiparous women. Data were found searching The PubMed, Cochrane library and Embase databases electronically. Studies investigating the risk of OASIS in vacuum-assisted delivery with and without the use of mediolateral or lateral episiotomy were considered for inclusion...
October 26, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27318182/shoulder-dystocia-guidelines-for-clinical-practice-from-the-french-college-of-gynecologists-and-obstetricians-cngof
#7
REVIEW
Loïc Sentilhes, Marie-Victoire Sénat, Anne-Isabelle Boulogne, Catherine Deneux-Tharaux, Florent Fuchs, Guillaume Legendre, Camille Le Ray, Emmanuel Lopez, Thomas Schmitz, Véronique Lejeune-Saada
Shoulder dystocia (SD) is defined as a vaginal delivery in cephalic presentation that requires additional obstetric maneuvers to deliver the fetus after the head has delivered and gentle traction has failed. It complicates 0.5-1% of vaginal deliveries. Risks of brachial plexus birth injury (level of evidence [LE]3), clavicle and humeral fracture (LE3), perinatal asphyxia (LE2), hypoxic-ischemic encephalopathy (LE3) and perinatal mortality (LE2) increase with SD. Its main risk factors are previous SD and macrosomia, but both are poorly predictive; 50-70% of SD cases occur in their absence, and most deliveries when they are present do not result in SD...
August 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27862859/management-of-monochorionic-twin-pregnancy-green-top-guideline-no-51
#8
(no author information available yet)
No abstract text is available yet for this article.
November 16, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27727018/macrosomia
#9
Edward Araujo Júnior, Alberto Borges Peixoto, Ana Cristina Perez Zamarian, Júlio Elito Júnior, Gabriele Tonni
Fetal macrosomia is defined as birth weight >4000 g and is associated with several maternal and fetal complications such as maternal birth canal trauma, shoulder dystocia, and perinatal asphyxia. Early identification of risk factors could allow preventive measures to be taken to avoid adverse perinatal outcomes. Prenatal diagnosis is based on two-dimensional ultrasound formulae, but accuracy is low, particularly at advanced gestation. Three-dimensional ultrasound could be an alternative to soft tissue monitoring, allowing better prediction of birth weight than two-dimensional ultrasound...
September 15, 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27729208/screening-and-prevention-of-stillbirth
#10
Gordon C S Smith
Stillbirth is delivery of a baby at or after 24 weeks of gestational age (UK definition) not showing any signs of life. It affects almost one in 200 pregnancies and is the single major cause of perinatal death. Stillbirth is associated with a wide range of maternal demographic characteristics, but most of the variations in stillbirth risk are independent of these characteristics. Stillbirth is the end point of multiple processes, but the single most common cause is probably placental dysfunction. Stillbirth is associated with a wide range of biochemical and ultrasonic predictors, but there is limited evidence to support population-based screening...
September 15, 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27743768/epidemiology-of-epithelial-ovarian-cancer
#11
Penelope M Webb, Susan J Jordan
Globally, ovarian cancer is the seventh most common cancer in women and the eighth most common cause of cancer death, with five-year survival rates below 45%. Although age-standardised rates are stable or falling in most high-income countries, they are rising in many low and middle income countries. Furthermore, with increasing life-expectancy, the number of cases diagnosed each year is increasing. To control ovarian cancer we need to understand the causes. This will allow better prediction of those at greatest risk for whom screening might be appropriate, while identification of potentially modifable causes provides an opportunity for intervention to reduce rates...
October 3, 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27756534/antenatal-fetal-surveillance-assessment-of-the-afv
#12
Dawn S Hughes, Everett F Magann
The evaluation of amniotic fluid volume (AFV) is an established part of the antenatal surveillance of pregnancies at risk for an adverse pregnancy outcome. The two most commonly used ultrasound techniques to estimate AFV are the amniotic fluid index (AFI) and the single deepest pocket (SDP). Four studies have defined normal AFVs, and although their normal volumes have similarities, there are also differences primarily due to the statistical methodology used in each study. Dye-determined AFV correlates with ultrasound estimates for normal fluid volumes but correlates poorly for oligohydramnios and polyhydramnios...
September 16, 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27780698/management-of-borderline-ovarian-tumours
#13
REVIEW
David M Gershenson
Approximately 3000 American women are diagnosed with borderline ovarian tumours annually. Borderline tumours are similar to other types of adnexal masses. Prognostic factors include the International Federation of Gynecology and Obstetrics (FIGO) stage, presence of peritoneal implants, micropapillary pattern (for serous histology), microinvasion and intra-epithelial carcinoma (for mucinous histology). Approximately 65-70% of serous tumours and 90% of mucinous tumours are stage I, and 30% and 10%, respectively, are associated with extra-ovarian spread...
October 3, 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27784616/the-role-of-leiomyomas-in-the-genesis-of-abnormal-uterine-bleeding-aub
#14
REVIEW
Ricardo Bassil Lasmar, Bernardo Portugal Lasmar
Abnormal uterine bleeding (AUB) is the major complaint in approximately one-third of gynecological visits in premenopausal women, and in >70% of appointments of perimenopausal and postmenopausal women. Uterine myoma is one of the main causes of AUB during menacme, especially when it is submucosal. The association of myoma and AUB may be related to several factors, from local alterations of angiogenic and vasoactive substances to changes in uterine contractility. The objective of this paper is to show the different associations of myoma and AUB...
October 1, 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27810281/adenomyosis-and-abnormal-uterine-bleeding-aub-a-pathogenesis-diagnosis-and-management
#15
REVIEW
Jason A Abbott
The complex pathogenesis and variable presentation of adenomyosis make it one of the most difficult of the FIGO PALM-COIEN abnormal uterine bleeding group to diagnose and treat. Basic clinical parameters such as prevalence are difficult to accurately assess because histological confirmation is usually employed; however, because of the access to and accuracy and utilization of transvaginal ultrasound and other advanced imaging techniques such as MRI, noninvasive diagnosis is recognized to be highly accurate...
September 30, 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27815588/the-new-sepsis-consensus-definitions-the-good-the-bad-and-the-ugly
#16
EDITORIAL
Charles L Sprung, Roland M H Schein, Robert A Balk
No abstract text is available yet for this article.
December 2016: Intensive Care Medicine
https://www.readbyqxmd.com/read/27810551/antiplatelet-therapy-before-or-after-16-weeks-gestation-for-preventing-preeclampsia-an-individual-participant-data-meta-analysis
#17
REVIEW
Shireen Meher, Lelia Duley, Kylie Hunter, Lisa Askie
BACKGROUND: The optimum time for commencing antiplatelet therapy for the prevention of preeclampsia and its complications is unclear. Aggregate data meta-analyses suggest that aspirin is more effective if given prior to 16 weeks' gestation, but data are limited because of an inability to place women in the correct gestational age subgroup from relevant trials. OBJECTIVE: The objective of the study was to use the large existing individual participant data set from the Perinatal Antiplatelet Review of International Studies Collaboration to assess whether the treatment effects of antiplatelet agents on preeclampsia and its complications vary based on whether treatment is started before or after 16 weeks' gestation...
November 1, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27466209/uterine-fibroid-management-from-the-present-to-the-future
#18
REVIEW
Jacques Donnez, Marie-Madeleine Dolmans
Uterine fibroids (also known as leiomyomas or myomas) are the most common form of benign uterine tumors. Clinical presentations include abnormal bleeding, pelvic masses, pelvic pain, infertility, bulk symptoms and obstetric complications.Almost a third of women with leiomyomas will request treatment due to symptoms. Current management strategies mainly involve surgical interventions, but the choice of treatment is guided by patient's age and desire to preserve fertility or avoid 'radical' surgery such as hysterectomy...
November 2016: Human Reproduction Update
https://www.readbyqxmd.com/read/27825977/management-of-women-with-human-papillomavirus-persistence-long-term-follow-up-of-a-randomized-clinical%C3%A2-trial
#19
Kristina Elfgren, K Miriam Elfström, Pontus Naucler, Lisen Arnheim-Dahlström, Joakim Dillner
BACKGROUND: Introduction of human papillomavirus-based screening is ongoing in many countries, given its higher sensitivity and longer-lasting protection compared with cytology-based screening. However, optimal clinical management of human papillomavirus-positive but cytology-negative women is unclear, and additional studies with clinical follow-up are warranted. OBJECTIVE: The aim of the current study was to investigate the long-term outcomes of the clinical management used in a double-blind, randomized clinical trial of human papillomavirus screening conducted in the context of the routine, organized screening program in Sweden...
November 5, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27813249/diagnosis-and-management-of-ectopic-pregnancy-green-top-guideline-no-21
#20
(no author information available yet)
No abstract text is available yet for this article.
November 3, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
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