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Epilepsy

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69 papers 0 to 25 followers
https://www.readbyqxmd.com/read/28677853/response-to-the-numbering-of-seizure-types
#1
LETTER
Robert S Fisher, J Helen Cross, Carol D'Souza, Jacqueline A French, Sheryl Haut, Norimichi Higurashi, Edouard Hirsch, Floor E Jansen, Lieven Lagae, Solomon L Moshe, Saul R Korey, Dominick P Purpura, Jukka Peltola, Eliane Roulet Perez, Ingrid E Scheffer, Andreas Schulze-Bonhage, Ernest Somerville, Michael Sperling, Elza Marcia Yacubian, Sameer M Zuberi
No abstract text is available yet for this article.
July 2017: Epilepsia
https://www.readbyqxmd.com/read/28677857/the-new-ilae-seizure-classification-63-seizure-types
#2
LETTER
Sándor Beniczky, Guido Rubboli, Harald Aurlien, Lawrence J Hirsch, Eugen Trinka, Donald L Schomer
No abstract text is available yet for this article.
July 2017: Epilepsia
https://www.readbyqxmd.com/read/28744852/phenomenological-network-models-lessons-for-epilepsy-surgery
#3
Jurgen Hebbink, Hil Meijer, Geertjan Huiskamp, Stephan van Gils, Frans Leijten
The current opinion in epilepsy surgery is that successful surgery is about removing pathological cortex in the anatomic sense. This contrasts with recent developments in epilepsy research, where epilepsy is seen as a network disease. Computational models offer a framework to investigate the influence of networks, as well as local tissue properties, and to explore alternative resection strategies. Here we study, using such a model, the influence of connections on seizures and how this might change our traditional views of epilepsy surgery...
October 2017: Epilepsia
https://www.readbyqxmd.com/read/18777484/the-use-of-psychotropic-drugs-in-epilepsy-what-every-neurologist-should-know
#4
REVIEW
Andres M Kanner
Psychiatric disorders, such as mood, anxiety, attention deficit, and psychotic disorders, are among the most frequent comorbidities experienced by patients with epilepsy. While these psychiatric disorders have typically been considered as one of its complications, there is increasing evidence of a bidirectional relationship between the seizure disorder and mood and ADHD. Indeed, not only are patients with epilepsy at greater risk of developing these two disorders, but patients with mood and attention deficit disorders are at greater risk of developing epilepsy...
July 2008: Seminars in Neurology
https://www.readbyqxmd.com/read/23021287/uncovering-the-neurobehavioural-comorbidities-of-epilepsy-over-the-lifespan
#5
REVIEW
Jack J Lin, Marco Mula, Bruce P Hermann
Epilepsy is a common neurological disorder that is complicated by psychiatric, cognitive, and social comorbidities that have become a major target of concern and investigation in view of their adverse effect on the course and quality of life. In this report we define the specific psychiatric, cognitive, and social comorbidities of paediatric and adult epilepsy, their epidemiology, and real life effects; examine the relation between epilepsy syndromes and the risk of neurobehavioural comorbidities; address the lifespan effect of epilepsy on brain neurodevelopment and brain ageing and the risk of neurobehavioural comorbidities; consider the overarching effect of broader brain disorders on both epilepsy and neurobehavioural comorbidities; examine directions of causality and the contribution of selected epilepsy-related characteristics; and outline clinic-friendly screening approaches for these problems and recommended pharmacological, behavioural, and educational interventions...
September 29, 2012: Lancet
https://www.readbyqxmd.com/read/24929650/epilepsy-and-its-main-psychiatric-comorbidities-in-adults-and-children
#6
REVIEW
Alberto Verrotti, Danilo Carrozzino, Maddalena Milioni, Maria Minna, Mario Fulcheri
Psychiatric disorders seem to be more frequent in patients with epilepsy (PWE) than the general population. Although researchers have documented a strong association between epilepsy and psychiatric comorbidities, the nature of this relationship is poorly understood. According to this, psychiatric diseases are often underdiagnosed and undertreated in PWE with further decrease of the quality of life of patients. The aim of the review was to examine the most frequent psychiatric comorbidities in adults with epilepsy (AWE) and the main psychiatric comorbidities in children with epilepsy (CWE) in order to better understand the relationship between epilepsy and the development of psychiatric disorders...
August 15, 2014: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/26874243/psychiatric-comorbidity-in-psychogenic-nonepileptic-seizures-compared-with-epilepsy
#7
REVIEW
William Diprose, Frederick Sundram, David B Menkes
OBJECTIVES: Psychogenic nonepileptic seizures (PNESs) are closely linked with psychological distress, but their etiology is not well-understood. We reviewed psychiatric comorbidity in PNESs and epileptic seizures (ESs) with an aim to assist understanding, diagnosis, and management of PNESs. METHODS: A search of Web of Science, MEDLINE (PubMed), PsycINFO, and Scopus identified 32 relevant studies on the prevalence of psychiatric comorbidity in PNESs. We used meta-analysis to compare psychiatric comorbidity between PNESs and ESs...
March 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28621770/epilepsy-a-new-guideline-on-sudden-unexpected-death-in-epilepsy
#8
Daniel Friedman
No abstract text is available yet for this article.
July 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28625946/educational-needs-of-epileptologists-regarding-psychiatric-comorbidities-of-the-epilepsies-a-descriptive-quantitative-survey
#9
Marco Mula, Esper Cavalheiro, Alla Guekht, Andres M Kanner, Hyang Woon Lee, Çiğdem Özkara, Alfredo Thomson, Sarah J Wilson
Psychiatric disorders are relatively frequent comorbidities in epilepsy and they have an impact on morbidity, mortality, and quality of life. This is a report from the Task Force on Education of the ILAE Commission on Neuropsychiatry based on a survey about educational needs of epileptologists regarding management of the psychiatric comorbidities of epilepsy. The Task Force designed a quantitative questionnaire to survey the self-perceived confidence of child and adult epileptologists and psychiatrists in managing major psychiatric comorbidities of epilepsy to identify: (1) critical areas of improvement from a list of skills that are usually considered necessary for effective management of these conditions, and (2) the preferred educational format for improving these skills...
June 1, 2017: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/28622545/diagnosing-psychogenic-nonepileptic-seizures-video-eeg-monitoring-suggestive-seizure-induction-and-diagnostic-certainty
#10
Stoyan Popkirov, Johannes Jungilligens, Wenke Grönheit, Jörg Wellmer
Psychogenic nonepileptic seizures (PNES) can remain undiagnosed for many years, leading to unnecessary medication and delayed treatment. A recent report by the International League Against Epilepsy Nonepileptic Seizures Task Force recommends a staged approach to the diagnosis of PNES (LaFrance, et al., 2013). We aimed to investigate its practical utility, and to apply the proposed classification to evaluate the role of long-term video-EEG monitoring (VEEG) and suggestive seizure induction (SSI) in PNES workup...
June 13, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28623727/current-clinical-magnetoencephalography-practice-across-europe-are-we-closer-to-use-meg-as-an-established-clinical-tool
#11
Xavier De Tiège, Daniel Lundqvist, Sándor Beniczky, Stefano Seri, Ritva Paetau
PURPOSE: This comprehensive survey aims at characterizing the current clinical use of magnetoencephalography (MEG) across European MEG centres. METHODS: Forty-four MEG centres across Europe were contacted in May 2015 via personalized e-mail to contribute to survey. The web-based survey was available on-line for 1 month and the MEG centres that did not respond were further contacted to maximize participation. RESULTS: Among the 57% of responders, 12 centres from 10 different countries reported to use MEG for clinical applications...
August 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28621765/epilepsy-cannabidiol-reduces-seizure-frequency-in-dravet-syndrome
#12
Charlotte Ridler
No abstract text is available yet for this article.
July 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28622421/how-to-record-high-frequency-oscillations-in-epilepsy-a-practical-guideline
#13
REVIEW
Maeike Zijlmans, Gregory A Worrell, Matthias Dümpelmann, Thomas Stieglitz, Andrei Barborica, Marcel Heers, Akio Ikeda, Naotaka Usui, Michel Le Van Quyen
OBJECTIVE: Technology for localizing epileptogenic brain regions plays a central role in surgical planning. Recent improvements in acquisition and electrode technology have revealed that high-frequency oscillations (HFOs) within the 80-500 Hz frequency range provide the neurophysiologist with new information about the extent of the epileptogenic tissue in addition to ictal and interictal lower frequency events. Nevertheless, two decades after their discovery there remain questions about HFOs as biomarkers of epileptogenic brain and there use in clinical practice...
August 2017: Epilepsia
https://www.readbyqxmd.com/read/28544889/juvenile-myoclonic-epilepsy-as-a-spectrum-disorder-a-focused-review
#14
REVIEW
Betül Baykan, Peter Wolf
In consequence of newer research juvenile myoclonic epilepsy (JME) is no longer seen as a homogeneous disease. The causes of the existing variance are only partially known yet. We discuss to what extent the phenotypical spectrum of this polygenetically determined disorder expresses genetically defined endophenotypes, or is due to mere quantitative differences in the expression of the core phenotype. Of the three common seizure types of JME, myoclonic, generalized tonic-clonic and absences, absences also occur independently and are strong candidates for an endophenotype...
July 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28551500/psychiatric-side-effects-and-antiepileptic-drugs-observations-from-prospective-audits
#15
Linda J Stephen, Abbie Wishart, Martin J Brodie
Psychiatric comorbidities are common in people with epilepsy. A retrospective study of characteristics associated with withdrawal due to psychiatric side effects was undertaken in patients with treated epilepsy participating in prospective audits with new antiepileptic drugs (AEDs). A total of 1058 treated patients with uncontrolled seizures (942 focal-onset seizures, 116 generalized genetic epilepsies [GGEs]) participated in eight prospective, observational audits from 1996 to 2014. These patients were prescribed adjunctive topiramate (n=170), levetiracetam (n=220), pregabalin (n=135), zonisamide (n=203), lacosamide (n=160), eslicarbazepine acetate (n=52), retigabine (n=64), or perampanel (n=54)...
June 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28543030/defining-epileptogenic-networks-contribution-of-seeg-and-signal-analysis
#16
REVIEW
Fabrice Bartolomei, Stanislas Lagarde, Fabrice Wendling, Aileen McGonigal, Viktor Jirsa, Maxime Guye, Christian Bénar
Epileptogenic networks are defined by the brain regions involved in the production and propagation of epileptic activities. In this review we describe the historical, methodologic, and conceptual bases of this model in the analysis of electrophysiologic intracerebral recordings. In the context of epilepsy surgery, the determination of cerebral regions producing seizures (i.e., the "epileptogenic zone") is a crucial objective. In contrast with a traditional focal vision of focal drug-resistant epilepsies, the concept of epileptogenic networks has been progressively introduced as a model better able to describe the complexity of seizure dynamics and realistically describe the distribution of epileptogenic anomalies in the brain...
July 2017: Epilepsia
https://www.readbyqxmd.com/read/27322347/modern-management-of-seizures-and-epilepsy
#17
REVIEW
Markus Gschwind, Margitta Seeck
Complete seizure control is achieved in 40-50% of all epileptic patients with drug treatment, as reported in most epidemiological studies. Many effective antiepileptic drugs with a favourable profile are available in Switzerland, allowing treatment tailored to the patient's needs. Unfortunately, up to 40-50% of all patients will eventually relapse (pharmacoresistant epilepsy). These patients run a high risk of additional morbidity and mortality. Possible pharmacoresistant epilepsy should be considered early in the disease, when there is a lack of response to the first antiepileptic drug, since only 14% of those will respond to a second drug, and only 2% to a third drug if the second fails too...
2016: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28532712/photosensitivity-and-epilepsy-current-concepts-and-perspectives-a-narrative-review
#18
REVIEW
A Martins da Silva, Bárbara Leal
The authors review the influence of photic stimuli on the generation of epileptic seizures, addressing the first descriptions of the phenomenon and its subsequent exploration. Initially defined in the 1950's, links between intermittent photic stimulation (IPS) and seizures were well understood by the 1970. Since then the increasing exposure to photic stimuli associated with modern life (for instance through TVs, patterns, computer games and electronic instruments with flickering displays) has led to an increased interest in this issue...
April 5, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28499853/epilepsy-and-two-evolving-societies
#19
Adrian Burton
No abstract text is available yet for this article.
May 9, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28460793/forced-normalization-antagonism-between-epilepsy-and-psychosis
#20
REVIEW
Yasuhiko Kawakami, Yasuhiko Itoh
The antagonism between epilepsy and psychosis has been discussed for a long time. Landolt coined the term "forced normalization" in the 1950s to describe psychotic episodes associated with the remission of seizures and disappearance of epileptiform activity on electroencephalograms in individuals with epilepsy. Since then, neurologists and psychiatrists have been intrigued by this phenomenon. However, although collaborative clinical studies and basic experimental researches have been performed, the mechanism of forced normalization remains unknown...
May 2017: Pediatric Neurology
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