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Chagas

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https://www.readbyqxmd.com/read/27550362/pharmacokinetics-of-benznidazole-in-chagas-disease-a-systematic-review-and-meta-analysis
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Matthew O Wiens, Steve Kanters, Edward Mills, Alejandro A Peregrina Lucano, Silvia Gold, Dieter Ayers, Luis Ferrero, Alejandro Krolewiecki
BACKGROUND: Chagas disease is a neglected parasitic illness affecting approximately 8 million people, predominantly in Latin America. Benznidazole is the drug of choice for treatment, although availability has been limited. A paucity of knowledge of the pharmacokinetic properties of this drug have contributed to limited availability in several jurisdictions. OBJECTIVE: To conduct systematic literature review and Bayesian meta-analysis of pharmacokinetic studies to improve estimates of basic pharmacokinetic properties of benznidazole...
August 22, 2016: Antimicrobial Agents and Chemotherapy
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