collection
MENU ▼
Read by QxMD icon Read
search

Coenzyme Q

shared collection
4 papers 0 to 25 followers
By Faye Kehler Family Physician and GP Anesthetist since 1987 interested in all aspects of Medicine
https://www.readbyqxmd.com/read/22431837/antioxidants-for-alzheimer-disease-a-randomized-clinical-trial-with-cerebrospinal-fluid-biomarker-measures
#1
RANDOMIZED CONTROLLED TRIAL
Douglas R Galasko, Elaine Peskind, Christopher M Clark, Joseph F Quinn, John M Ringman, Gregory A Jicha, Carl Cotman, Barbara Cottrell, Thomas J Montine, Ronald G Thomas, Paul Aisen
OBJECTIVE: To evaluate whether antioxidant supplements presumed to target specific cellular compartments affected cerebrospinal fluid (CSF) biomarkers. DESIGN: Double-blind, placebo-controlled clinical trial. SETTING: Academic medical centers. PARTICIPANTS: Subjects with mild to moderate Alzheimer disease. INTERVENTION: Random assignment to treatment for 16 weeks with 800 IU/d of vitamin E (α-tocopherol) plus 500 mg/d of vitamin C plus 900 mg/d of α-lipoic acid (E/C/ALA); 400 mg of coenzyme Q 3 times/d; or placebo...
July 2012: Archives of Neurology
https://www.readbyqxmd.com/read/20818733/coenzyme-q-and-mitochondrial-disease
#2
REVIEW
Catarina M Quinzii, Michio Hirano
Coenzyme Q(10) (CoQ(10)) is an essential electron carrier in the mitochondrial respiratory chain and an important antioxidant. Deficiency of CoQ(10) is a clinically and molecularly heterogeneous syndrome, which, to date, has been found to be autosomal recessive in inheritance and generally responsive to CoQ(10) supplementation. CoQ(10) deficiency has been associated with five major clinical phenotypes: (1) encephalomyopathy, (2) severe infantile multisystemic disease, (3) cerebellar ataxia, (4) isolated myopathy, and (5) nephrotic syndrome...
2010: Developmental Disabilities Research Reviews
https://www.readbyqxmd.com/read/20012276/current-state-of-coenzyme-q-10-production-and-its-applications
#3
REVIEW
Marimuthu Jeya, Hee-Jung Moon, Jeong-Lim Lee, In-Won Kim, Jung-Kul Lee
Coenzyme Q(10) (CoQ(10)), an obligatory cofactor in the aerobic respiratory electron transfer for energy generation, is formed from the conjugation of a benzoquinone ring with a hydrophobic isoprenoid chain. CoQ(10) is now used as a nutritional supplement because of its antioxidant properties and is beneficial in the treatment of several human diseases when administered orally. Bioprocesses have been developed for the commercial production of CoQ(10) because of its increased demand, and these bioprocesses depend on microbes that produce high levels of CoQ(10) naturally...
February 2010: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/17950797/effect-of-coenzyme-q-10-supplementation-on-simvastatin-induced-myalgia
#4
RANDOMIZED CONTROLLED TRIAL
Joanna M Young, Christopher M Florkowski, Sarah L Molyneux, Roberta G McEwan, Christopher M Frampton, Peter M George, Russell S Scott
Myalgia is the most frequently reported adverse side effect associated with statin therapy and often necessitates reduction in dose, or the cessation of therapy, compromising cardiovascular risk management. One postulated mechanism for statin-related myalgia is mitochondrial dysfunction through the depletion of coenzyme Q(10), a key component of the mitochondrial electron transport chain. This pilot study evaluated the effect of coenzyme Q(10) supplementation on statin tolerance and myalgia in patients with previous statin-related myalgia...
November 1, 2007: American Journal of Cardiology
1
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"