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6 papers 0 to 25 followers Medical doctor, nephrology
By Ergün Parmaksız Medical doctor(nefrology special)
Mark A Lusco, Agnes B Fogo, Behzad Najafian, Charles E Alpers
No abstract text is available yet for this article.
October 2015: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
Patricia Palcu, Natalie Dion, Louis-Georges Ste-Marie, David Goltzman, Ina Radziunas, Paul D Miller, Sophie A Jamal
Teriparatide, a recombinant form of parathyroid hormone, is an anabolic agent approved for use in women and men with osteoporosis. However, it is not well studied in people with chronic kidney disease (CKD). We report on a patient with stage 5 CKD treated with dialysis who presented to our clinic with multiple fractures, including bilateral nondisplaced pelvic fractures resulting in chronic pain and interfering with the patient's ability to work. Bone histomorphometry demonstrated low-turnover bone disease, and he was treated with 20μg of teriparatide (subcutaneous injection) every morning for 24 months...
June 2015: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
Rosa Marlene Viero, Márcia Guimarães da Silva, Daniela Cristina dos Santos, Maria Fernanda Cordeiro de Carvalho, Luis Gustavo Modelli de Andrade
BACKGROUND: Evidences suggest a role of renin-angiotensin system (RAS) in the development of chronic allograft injury. METHODS: We correlated intrarenal angiotensin-converting enzyme, angiotensin II (Angio II) and transforming growth factor β1 (TGFβ1) expression in 58 biopsies-proven chronic allograft nephropathy (CAN) with tissue injury and allograft survival. RESULTS: The biopsies with CAN were graded according to Banff classification as I (22 cases), II (17) and III (19); 27 biopsies also showed a mononuclear inflammatory infiltrate in scarred areas...
June 2015: Renal Failure
D Farmakiotis, D P Kontoyiannis
Invasive fungal infections (IFIs) are being increasingly recognized in solid organ transplant (SOT) recipients, and delayed diagnosis can lead to graft loss and death. Therefore, there is a low threshold for prophylaxis and early initiation of empiric antifungal treatment, in this patient population. Meanwhile, the increasing consumption of antifungals is associated with high cost, medication toxicities and the emergence of resistance in Candida species, all of which call for rational use of antifungal agents...
May 2015: American Journal of Transplantation
Chantal Loirat, Véronique Frémeaux-Bacchi
Atypical hemolytic uremic syndrome (HUS) secondary to anti-factor H autoantibodies has a poor prognosis. The study by Sinha et al. of a large cohort of Indian children makes a substantial contribution to improved management of this form of HUS by showing that standardized titration of anti-factor H autoantibodies is applicable worldwide and that early treatment initiation and guidance of maintenance treatment by autoantibody titer monitoring significantly improve outcomes.
May 2014: Kidney International
Ala A Abudayyeh, Amit Lahoti, Abdulla K Salahudeen
No abstract text is available yet for this article.
May 2014: Kidney International
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