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Good clinical evidence — Neurology

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7 papers 0 to 25 followers The most important evidence to take decisions in the practice of Neurology
By Daniel Vela-Duarte Neurology / Vascular Neurology
Duncan Wilson, Andreas Charidimou, Gareth Ambler, Zoe V Fox, Simone Gregoire, Phillip Rayson, Toshio Imaizumi, Felix Fluri, Hiromitsu Naka, Solveig Horstmann, Roland Veltkamp, Peter M Rothwell, Vincent I H Kwa, Vincent Thijs, Yong-Seok Lee, Young Dae Kim, Yining Huang, Ka Sing Wong, Hans Rolf Jäger, David J Werring
OBJECTIVE: To determine associations between cerebral microbleed (CMB) burden with recurrent ischemic stroke (IS) and intracerebral hemorrhage (ICH) risk after IS or TIA. METHODS: We identified prospective studies of patients with IS or TIA that investigated CMBs and stroke (ICH and IS) risk during ≥3 months follow-up. Authors provided aggregate summary-level data on stroke outcomes, with CMBs categorized according to burden (single, 2-4, and ≥5 CMBs) and distribution...
October 4, 2016: Neurology
Agnes van Sonderen, Roland D Thijs, Elias C Coenders, Lize C Jiskoot, Esther Sanchez, Marienke A A M de Bruijn, Marleen H van Coevorden-Hameete, Paul W Wirtz, Marco W J Schreurs, Peter A E Sillevis Smitt, Maarten J Titulaer
OBJECTIVE: This nationwide study gives a detailed description of the clinical features and long-term outcome of anti-leucine-rich glioma-inactivated 1 (LGI1) encephalitis. METHODS: We collected patients prospectively from October 2013, and retrospectively from samples sent to our laboratory from January 2007. LGI1 antibodies were confirmed with both cell-based assay and immunohistochemistry. Clinical information was obtained in interviews with patients and their relatives and from medical records...
October 4, 2016: Neurology
Seung Yoon Song, Seong Yeol Ahn, Jong Ju Rhee, Jong Won Lee, Jin Woo Hur, Hyun Koo Lee
OBJECTIVE: To determine whether the use of contrast enhancement (especially its extent) predicts malignant brain edema after intra-arterial thrombectomy (IAT) in patients with acute ischemic stroke. METHODS: We reviewed the records of patients with acute ischemic stroke who underwent IAT for occlusion of the internal carotid artery or the middle cerebral artery between January 2012 and March 2015. To estimate the extent of contrast enhancement (CE), we used the contrast enhancement area ratio (CEAR)-i...
October 2015: Journal of Korean Neurosurgical Society
Yilong Wang, S Claiborne Johnston, Yongjun Wang
No abstract text is available yet for this article.
October 3, 2013: New England Journal of Medicine
S Horstmann, T Rizos, M Lauseker, M Möhlenbruch, E Jenetzky, W Hacke, Th Steiner, R Veltkamp
Intracerebral hemorrhage (ICH) is the most devastating complication of oral anticoagulation (OAC). As the number of patients on long-term OAC is expected to rise, the proportion of intracerebral hemorrhage related to OAC (OAC-ICH) in relation to spontaneous ICH (spont-ICH) is expected to increase as well. We determined the proportion of OAC-ICH in consecutive stroke patients and explored differences between OAC-ICH and spont-ICH regarding initial volume, hematoma expansion and outcome. Our prospective study consecutively enrolled patients with supra- and infratentorial ICH...
August 2013: Journal of Neurology
Y-W Chen, S-C Tang, L-K Tsai, S-J Yeh, H-Y Chiou, P-K Yip, J-S Jeng
BACKGROUND AND PURPOSE: Anticoagulant and antiplatelets for prevention of ischaemic stroke and cardiovascular diseases may increase the risk of intracerebral hemorrhage (ICH). This study aimed to investigate the influence of pre-ICH use of anticoagulant and antiplatelets on ICH patients. METHODS: Consecutive patients with acute spontaneous ICH registered in a single-center stroke registry during 2001 to 2010 were analyzed and categorized according to their pre-ICH use of warfarin (Group I), antiplatelets (Group II), or neither (Group III)...
August 2013: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
Thomas G Brott, Robert W Hobson, George Howard, Gary S Roubin, Wayne M Clark, William Brooks, Ariane Mackey, Michael D Hill, Pierre P Leimgruber, Alice J Sheffet, Virginia J Howard, Wesley S Moore, Jenifer H Voeks, L Nelson Hopkins, Donald E Cutlip, David J Cohen, Jeffrey J Popma, Robert D Ferguson, Stanley N Cohen, Joseph L Blackshear, Frank L Silver, J P Mohr, Brajesh K Lal, James F Meschia
BACKGROUND: Carotid-artery stenting and carotid endarterectomy are both options for treating carotid-artery stenosis, an important cause of stroke. METHODS: We randomly assigned patients with symptomatic or asymptomatic carotid stenosis to undergo carotid-artery stenting or carotid endarterectomy. The primary composite end point was stroke, myocardial infarction, or death from any cause during the periprocedural period or any ipsilateral stroke within 4 years after randomization...
July 1, 2010: New England Journal of Medicine
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