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Neurodevelopmental outcome

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Fredrik Serenius, Uwe Ewald, Aijaz Farooqi, Vineta Fellman, Maria Hafström, Kerstin Hellgren, Karel Maršál, Andreas Ohlin, Elisabeth Olhager, Karin Stjernqvist, Bo Strömberg, Ulrika Ådén, Karin Källén
Importance: Active perinatal care increases the rate of survival of extremely preterm infants, but there are concerns that improved survival might increase the rate of disabled survivors. Objective: To determine the neurodevelopmental outcomes of a national cohort of children 6.5 years of age who had been born extremely preterm (<27 weeks' gestational age) in Sweden. Design, Setting, and Participants: Population-based prospective cohort study of consecutively born extremely preterm infants...
October 1, 2016: JAMA Pediatrics
Milla Ylijoki, Liisa Lehtonen, Annika Lind, Eeva Ekholm, Helena Lapinleimu, Harry Kujari, Leena Haataja
BACKGROUND: Chorioamnionitis, a risk factor for preterm delivery, has been suggested to be associated with suboptimal neurological development in premature infants. OBJECTIVE: To evaluate the association between chorioamnionitis and neurodevelopment in preterm infants at 5 years of age. Methods Very low birth weight and very low gestational age infants (n = 197) were recruited. Placental samples (n = 117) were evaluated for histological chorioamnionitis. Fetal histological chorioamnionitis was analyzed as a subgroup...
June 29, 2016: Neonatology
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