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Pediatric critical care medicine

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20 papers 0 to 25 followers
https://www.readbyqxmd.com/read/26719183/dopamine-increases-mortality-in-pediatric-septic-shock
#1
COMMENT
Paul E Marik
No abstract text is available yet for this article.
January 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27683607/clinical-classification-in-pediatric-pulmonary-arterial-hypertension-associated-with-congenital-heart-disease
#2
Willemijn M H Zijlstra, Johannes M Douwes, Mark-Jan Ploegstra, Usha Krishnan, Marcus T R Roofthooft, Hans L Hillege, D Dunbar Ivy, Erika B Rosenzweig, Rolf M F Berger
Congenital heart disease (CHD) is a frequent cause of pediatric pulmonary arterial hypertension (PAH), with diverse etiology and outcome. We aimed to describe phenotypic heterogeneity in pediatric PAH associated with CHD (PAH-CHD), assess the applicability of the Nice CHD classification, and explore whether this classification accurately reflects patient/disease characteristics and survival. All children with CHD from a contemporary cohort of consecutive pediatric PAH patients followed in three major referral centers (Denver, New York, the Netherlands) were characterized and classified on the basis of the latest proposed clinical classification for PAH-CHD (World Symposium on Pulmonary Hypertension, Nice, 2013)...
September 2016: Pulmonary Circulation
https://www.readbyqxmd.com/read/27749512/2016-update-for-the-rogers-textbook-of-pediatric-intensive-care-recognition-and-initial-management-of-shock
#3
Julie C Fitzgerald, Scott L Weiss, Niranjan Kissoon
OBJECTIVE: To review important articles in the field of pediatric shock and pediatric septic shock published subsequent to the Fifth Edition of the Rogers' Textbook of Pediatric Intensive Care. DATA SOURCES: The U.S. National Library of Medicine PubMed (www.ncbi.nlm.nih.gov/pubmed) was searched for combination of the term "pediatric" and the following terms: "sepsis, septic shock, shock, antibiotics, extracorporeal membrane oxygenation, and steroid." The abstract lists generated by these searches were screened for potential inclusion...
November 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27604388/high-dose-methylprednisolone-and-endothelial-glycocalyx-in-paediatric-heart-surgery
#4
E Pesonen, J Keski-Nisula, S Andersson, R Palo, J Salminen, P K Suominen
BACKGROUND: Corticosteroids are used in paediatric heart surgery to attenuate systemic inflammatory response. Glycocalyx regulates vascular permeability, shear stress and cell adhesion on the endothelium. Syndecan-1 serves as a biomarker of glycocalyx degradation. Hydrocortisone decreased endothelial glycocalyx degradation in an experimental model. Our hypothesis was that high-dose methylprednisolone decreases glycocalyx degradation as measured by plasma sydecan-1 concentration in children undergoing cardiac surgery...
November 2016: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/27585052/the-intracranial-pressure-cerebral-perfusion-pressure-time-integral-can-it-be-a-more-robust-predictor-of-outcomes-in-children-with-severe-traumatic-brain-injury
#5
Saptharishi Lalgudi Ganesan
No abstract text is available yet for this article.
September 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/26835574/rapid-intravenous-rehydration-therapy-in-children-with-acute-gastroenteritis-a-systematic-review
#6
REVIEW
Fatihi Hassan Soliman Toaimah, Hala Mohammad Fathi Mohammad
BACKGROUND: Rapid intravenous (IV) rehydration is commonly used for the management of pediatric gastroenteritis in the emergency department. The current practice shows wide variation in the volume and rate of rapid IV hydration. The aim of this review was to assess the efficacy of rapid IV rehydration compared with standard method in children with gastroenteritis. METHOD: MEDLINE (1946-2014), EMBASE (1974-2014), and CENTRAL via the Cochrane Library (Issue 8, 2014) were systematically searched to identify eligible studies...
February 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27077832/evaluation-of-the-early-use-of-albumin-in-children-with-extensive-burns-a-randomized-controlled-trial
#7
Maria Helena Müller Dittrich, Werther Brunow de Carvalho, Edson Lopes Lavado
OBJECTIVE: To compare early versus delayed albumin resuscitation in children with burns in terms of clinical outcome and response. DESIGN: Randomized controlled trial. SETTING: Burn center at a tertiary care teaching hospital. PATIENTS: Forty-six children aged 1-12 years with burns greater than 15-45% total body surface area admitted within 12 hours of burn injury. INTERVENTIONS: Fluid resuscitation was based on the Parkland formula (3 mL/kg/% total body surface area), adjusted according to urine output...
June 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27566963/reduction-in-procalcitonin-level-and-outcome-in-critically-ill-children-with-severe-sepsis-septic-shock-a-pilot-study
#8
Banani Poddar, Mohan Gurjar, Sushma Singh, Amita Aggarwal, Arvind Baronia
PURPOSE: To investigate if reduction in procalcitonin (PCT) provides useful information about 28-day mortality in children with severe sepsis or septic shock. MATERIALS AND METHODS: Design: Prospective observational study. SETTING: Mixed adult-pediatric intensive care unit in a teaching hospital. SUBJECTS: Children up to 18 years of age admitted with severe sepsis or septic shock between March 2011 and June 2013. Procalcitonin measured using electrochemiluminescence immunoassay on the day of admission with sepsis (D0) and 72-96 hours later (D4)...
December 2016: Journal of Critical Care
https://www.readbyqxmd.com/read/27230550/nutritional-support-for-critically-ill-children
#9
REVIEW
Ari Joffe, Natalie Anton, Laurance Lequier, Ben Vandermeer, Lisa Tjosvold, Bodil Larsen, Lisa Hartling
BACKGROUND: Nutritional support in the critically ill child has not been well investigated and is a controversial topic within paediatric intensive care. There are no clear guidelines as to the best form or timing of nutrition in critically ill infants and children. This is an update of a review that was originally published in 2009. . OBJECTIVES: The objective of this review was to assess the impact of enteral and parenteral nutrition given in the first week of illness on clinically important outcomes in critically ill children...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27198497/graft-versus-host-disease-in-paediatric-solid-organ-transplantation-a-review-of-the-literature
#10
REVIEW
Thomas Green, Jonathan Hind
GvHD is a rare and serious complication of organ transplantation. The literature is sparse following solid organ transplantation. The aim of this report was to review the literature of GvHD in paediatric solid organ transplantation. We searched PubMed for English-language full-text manuscripts between 1990 and 2015 for eligible studies. A total of 28 publications were found pertaining to paediatric GvHD following solid organ transplantation. GvHD had a mean incidence of 11% (range 8.3-13.4%) following SBTx and 1...
August 2016: Pediatric Transplantation
https://www.readbyqxmd.com/read/27501478/perioperative-complications-and-outcomes-in-children-with-cerebral-palsy-undergoing-scoliosis-surgery
#11
Anju A Bendon, Khristine A George, Davandra Patel
INTRODUCTION: Neuromuscular scoliosis is a known risk factor for postoperative complications after corrective spine surgery. Few studies have looked at the preoperative factors affecting postoperative complications in children with cerebral palsy. AIM: The aim of this study was to examine the factors that might influence postoperative course in patients with cerebral palsy undergoing spine surgery for scoliosis. METHODS: Nineteen case notes of children with cerebral palsy who had spine surgery (2008-2014) were reviewed retrospectively...
October 2016: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/27081478/probiotics-in-critically-ill-children
#12
REVIEW
Sunit C Singhi, Suresh Kumar
Gut microflora contribute greatly to immune and nutritive functions and act as a physical barrier against pathogenic organisms across the gut mucosa. Critical illness disrupts the balance between host and gut microflora, facilitating colonization, overgrowth, and translocation of pathogens and microbial products across intestinal mucosal barrier and causing systemic inflammatory response syndrome and sepsis. Commonly used probiotics, which have been developed from organisms that form gut microbiota, singly or in combination, can restore gut microflora and offer the benefits similar to those offered by normal gut flora, namely immune enhancement, improved barrier function of the gastrointestinal tract (GIT), and prevention of bacterial translocation...
2016: F1000Research
https://www.readbyqxmd.com/read/27456509/management-of-pediatric-trauma
#13
(no author information available yet)
Injury is still the number 1 killer of children ages 1 to 18 years in the United States (http://www.cdc.gov/nchs/fastats/children.htm). Children who sustain injuries with resulting disabilities incur significant costs not only for their health care but also for productivity lost to the economy. The families of children who survive childhood injury with disability face years of emotional and financial hardship, along with a significant societal burden. The entire process of managing childhood injury is enormously complex and varies by region...
August 2016: Pediatrics
https://www.readbyqxmd.com/read/27472255/risk-factors-of-acute-kidney-injury-in-critically-ill-children
#14
Morgan B Slater, Andrea Gruneir, Paula A Rochon, Andrew W Howard, Gideon Koren, Christopher S Parshuram
OBJECTIVES: Acute kidney injury may be promoted by critical illness, preexisting medical conditions, and treatments received both before and during ICU admission. We aimed to estimate the frequency of acute kidney injury during ICU treatment and to determine factors, occurring both before and during the ICU stay, associated with the development of acute kidney injury. DESIGN: Cohort study of critically ill children. SETTING: University-affiliated PICU...
September 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27472254/platelet-transfusions-in-pediatric-intensive-care
#15
Geneviève Du Pont-Thibodeau, Marisa Tucci, Nancy Robitaille, Thierry Ducruet, Jacques Lacroix
OBJECTIVES: To characterize the determinants of platelet transfusion in a PICU and determine whether there exists an association between platelet transfusion and adverse outcomes. DESIGN: Prospective observational single center study, combined with a self-administered survey. SETTING: PICU of Sainte-Justine Hospital, a university-affiliated tertiary care institution. PATIENTS: All children admitted to the PICU from April 2009 to April 2010...
September 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27472253/ketosis-after-cardiopulmonary-bypass-in-children-is-associated-with-an-inadequate-balance-between-oxygen-transport-and-consumption
#16
Philippe Klee, Delphine Arni, Sonja Saudan, Valérie M Schwitzgebel, Ruchika Sharma, Oliver Karam, Peter C Rimensberger
OBJECTIVES: Hyperglycemia after cardiac surgery and cardiopulmonary bypass in children has been associated with worse outcome; however, causality has never been proven. Furthermore, the benefit of tight glycemic control is inconsistent. The purpose of this study was to describe the metabolic constellation of children before, during, and after cardiopulmonary bypass, in order to identify a subset of patients that might benefit from insulin treatment. DESIGN: Prospective observational study, in which insulin treatment was initiated when postoperative blood glucose levels were more than 12 mmol/L (216 mg/dL)...
September 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27472252/a-randomized-controlled-comparison-of-the-internal-jugular-vein-and-the-subclavian-vein-as-access-sites-for-central-venous-catheterization-in-pediatric-cardiac-surgery
#17
Aynur Camkiran Firat, Pinar Zeyneloglu, Murat Ozkan, Arash Pirat
OBJECTIVES: To compare internal jugular vein and subclavian vein access for central venous catheterization in terms of success rate and complications. DESIGN: A 1:1 randomized controlled trial. SETTING: Baskent University Medical Center. PATIENTS: Pediatric patients scheduled for cardiac surgery. INTERVENTIONS: Two hundred and eighty children undergoing central venous catheterization were randomly allocated to the internal jugular vein or subclavian vein group during a period of 18 months...
September 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27472251/clinical-impact-of-accurate-point-of-care-glucose-monitoring-for-tight-glycemic-control-in-severely-burned-children
#18
Nam K Tran, Zachary R Godwin, Amanda N Steele, Steven E Wolf, Tina L Palmieri
OBJECTIVES: The goal of this study was to retrospectively evaluate the clinical impact of an accurate autocorrecting blood glucose monitoring system in children with severe burns. Blood glucose monitoring system accuracy is essential for providing appropriate intensive insulin therapy and achieving tight glycemic control in critically ill patients. Unfortunately, few comparison studies have been performed to evaluate the clinical impact of accurate blood glucose monitoring system monitoring in the high-risk pediatric burn population...
September 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27455114/protocolized-treatment-is-associated-with-decreased-organ-dysfunction-in-pediatric-severe-sepsis
#19
Fran Balamuth, Scott L Weiss, Julie C Fitzgerald, Katie Hayes, Sierra Centkowski, Marianne Chilutti, Robert W Grundmeier, Jane Lavelle, Elizabeth R Alpern
OBJECTIVES: To determine whether treatment with a protocolized sepsis guideline in the emergency department was associated with a lower burden of organ dysfunction by hospital day 2 compared to nonprotocolized usual care in pediatric patients with severe sepsis. DESIGN: Retrospective cohort study. SETTING: Tertiary care children's hospital from January 1, 2012, to March 31, 2014. SUBJECTS: Patients older than 56 days old and younger than 18 years old with international consensus defined severe sepsis and who required PICU admission within 24 hours of emergency department arrival were included...
September 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27387786/effect-of-ondansetron-on-qt-interval-in-patients-cared-for-in-the-picu
#20
Sangita Trivedi, Brenda Schiltz, Rakesh Kanipakam, Johan Martijn Bos, Michael J Ackerman, Yves Ouellette
OBJECTIVES: There is no evidence regarding the effect of ondansetron on the QT interval in pediatric patients in the ICU. This study aimed to describe the effect of ondansetron on the corrected QT interval in patients cared for in the PICU. DESIGN: Retrospective cohort, consecutive enrollment study. SETTING: Single-center, tertiary-level, medical/surgical PICU. PATIENTS: All patients less than 8 years old who received ondansetron over an 11-month period were included...
July 2016: Pediatric Critical Care Medicine
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