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Zika virus

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No abstract text is available yet for this article.
August 4, 2016: New England Journal of Medicine
Iara J F Motta, Bryan R Spencer, Suely G Cordeiro da Silva, Monica B Arruda, Jane A Dobbin, Yung B M Gonzaga, Ingrid P Arcuri, Rita C B S Tavares, Elias H Atta, Regina F M Fernandes, Deise A Costa, Liane J Ribeiro, Fabio Limonte, Luiza M Higa, Carolina M Voloch, Rodrigo M Brindeiro, Amilcar Tanuri, Orlando C Ferreira
To the Editor: Zika virus (ZIKV) is a mosquito-borne virus that has important secondary means of transmission that include perinatal and sexual modes. The potential for transmission in transfused donated blood components has been a concern owing to the detection of ZIKV viremia in healthy blood..
September 15, 2016: New England Journal of Medicine
Patrícia Brasil, Jose P Pereira, Claudia Raja Gabaglia, Luana Damasceno, Mayumi Wakimoto, Rita M Ribeiro Nogueira, Patrícia Carvalho de Sequeira, André Machado Siqueira, Liege M Abreu de Carvalho, Denise Cotrim da Cunha, Guilherme A Calvet, Elizabeth S Neves, Maria E Moreira, Ana E Rodrigues Baião, Paulo R Nassar de Carvalho, Carla Janzen, Stephanie G Valderramos, James D Cherry, Ana M Bispo de Filippis, Karin Nielsen-Saines
Background Zika virus (ZIKV) has been linked to neonatal microcephaly. To characterize the spectrum of ZIKV disease in pregnancy, we followed patients in Rio de Janeiro to describe clinical manifestations in mothers and repercussions of acute ZIKV infection in fetuses. Methods We enrolled pregnant women in whom a rash had developed within the previous 5 days and tested blood and urine specimens for ZIKV by reverse-transcriptase-polymerase-chain-reaction assays. We followed the women prospectively and collected clinical and ultrasonographic data...
March 4, 2016: New England Journal of Medicine
Jasper F W Chan, Garnet K Y Choi, Cyril C Y Yip, Vincent C C Cheng, Kwok-Yung Yuen
Unlike its mosquito-borne relatives, such as dengue, West Nile, and Japanese encephalitis viruses, which can cause severe human diseases, Zika virus (ZIKV) has emerged from obscurity by its association with a suspected "congenital Zika syndrome", while causing asymptomatic or mild exanthematous febrile infections which are dengue- or rubella-like in infected individuals. Despite having been discovered in Uganda for almost 60 years, <20 human cases were reported before 2007. The massive epidemics in the Pacific islands associated with the ZIKV Asian lineage in 2007 and 2013 were followed by explosive outbreaks in Latin America in 2015...
May 2016: Journal of Infection
Caroline Marrs, Gayle Olson, George Saade, Gary Hankins, Tony Wen, Janak Patel, Scott Weaver
The latest Zika virus (ZIKV) outbreak has reached epidemic proportions as it spreads throughout South and Central America. In November 2015, the Brazilian Ministry of Health reported a 20-fold increase in the number of cases of neonatal microcephaly, which corresponds geographically and temporally to the ZIKV outbreak. Case reports have provided some evidence of a causal link between maternal ZIKV infection, fetal microcephaly, and intracranial calcifications. The sparse data regarding ZIKV in pregnancy come solely from case reports and personal communications, and recommendations for management of ZIKV exposure during pregnancy are rapidly evolving...
June 2016: American Journal of Perinatology
Robert W Malone, Jane Homan, Michael V Callahan, Jill Glasspool-Malone, Lambodhar Damodaran, Adriano De Bernardi Schneider, Rebecca Zimler, James Talton, Ronald R Cobb, Ivan Ruzic, Julie Smith-Gagen, Daniel Janies, James Wilson
INTRODUCTION: Reports of high rates of primary microcephaly and Guillain-Barré syndrome associated with Zika virus infection in French Polynesia and Brazil have raised concerns that the virus circulating in these regions is a rapidly developing neuropathic, teratogenic, emerging infectious public health threat. There are no licensed medical countermeasures (vaccines, therapies or preventive drugs) available for Zika virus infection and disease. The Pan American Health Organization (PAHO) predicts that Zika virus will continue to spread and eventually reach all countries and territories in the Americas with endemic Aedes mosquitoes...
March 2016: PLoS Neglected Tropical Diseases
Rachael M Burke, Pranav Pandya, Eleni Nastouli, Philip Gothard
No abstract text is available yet for this article.
March 2016: British Journal of General Practice: the Journal of the Royal College of General Practitioners
Jernej Mlakar, Misa Korva, Nataša Tul, Mara Popović, Mateja Poljšak-Prijatelj, Jerica Mraz, Marko Kolenc, Katarina Resman Rus, Tina Vesnaver Vipotnik, Vesna Fabjan Vodušek, Alenka Vizjak, Jože Pižem, Miroslav Petrovec, Tatjana Avšič Županc
A widespread epidemic of Zika virus (ZIKV) infection was reported in 2015 in South and Central America and the Caribbean. A major concern associated with this infection is the apparent increased incidence of microcephaly in fetuses born to mothers infected with ZIKV. In this report, we describe the case of an expectant mother who had a febrile illness with rash at the end of the first trimester of pregnancy while she was living in Brazil. Ultrasonography performed at 29 weeks of gestation revealed microcephaly with calcifications in the fetal brain and placenta...
March 10, 2016: New England Journal of Medicine
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