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Hisato Takagi, Takuya Umemoto
OBJECTIVES: To determine whether transcatheter aortic valve implantation (TAVI) improves (or impairs) follow-up overall survival compared with surgical aortic valve replacement (SAVR), we performed a meta-analysis of observational studies with a propensity-score analysis and another meta-analysis of randomized controlled trials (RCTs). METHODS: Databases including MEDLINE and EMBASE were searched through October 2015 using PubMed and OVID. Eligible studies were observational studies with a propensity-score analysis or RCTs of TAVI versus SAVR enrolling patients with severe aortic stenosis and reporting follow-up overall survival or all-cause mortality as an outcome...
October 1, 2016: International Journal of Cardiology
Stefano Rosato, Francesco Santini, Marco Barbanti, Fausto Biancari, Paola D'Errigo, Francesco Onorati, Corrado Tamburino, Marco Ranucci, Remo Daniel Covello, Gennaro Santoro, Claudio Grossi, Martina Ventura, Danilo Fusco, Fulvia Seccareccia
BACKGROUND: The proven efficacy of transcatheter aortic valve implantation (TAVI) in high-risk patients is leading to the expansion of its indications toward lower-risk patients. However, this shift is not supported by meaningful evidence of its benefit over surgical aortic valve replacement (SAVR). This analysis aims to describe outcomes of TAVI versus SAVR in low-risk patients. METHODS AND RESULTS: We compared the outcome after TAVI and SAVR of low-risk patients (European System for Cardiac Operative Risk Evaluation II [EuroSCORE II] <4%) included in the Observational Study of Effectiveness of SAVR-TAVI Procedures for Severe Aortic Stenosis Treatment (OBSERVANT) study...
May 2016: Circulation. Cardiovascular Interventions
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