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Evasio Pasini, Roberto Aquilani, Francesco S Dioguardi, Giuseppe D'Antona, Mihai Gheorghiade, Heinrich Taegtmeyer
Hypercatabolic syndrome (HS) is a biochemical state characterized by increased circulating catabolic hormones (eg, cortisol, catecholamines) and inflammatory cytokines (eg, tumor necrosis factors, interleukin-1beta), and decreased anabolic insulin effects with consequent insulin resistance. The most important metabolic consequence of HS is the skeletal and cardiac muscle protein breakdown that releases amino acids (AAs), which in turn supports indispensable body energy requirements but also reduces skeletal and cardiac physiologic and metabolic functions...
June 2, 2008: American Journal of Cardiology
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