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First-Episode Psychosis

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2 papers 0 to 25 followers A collection addresing questions about recent onset psychotic illness, including diagnosing, evaluating, treating and managing psychosis
By Gabriel Elias Correa de Oliveira Psychiatrist, acting as supervisor in a Psychiatric Emergency ward and in a First-Episode Psychosis ambulatory
Benedicto Crespo-Facorro, Jose Maria Pelayo-Teran, Jacqueline Mayoral-van Son
Implementing the most suitable treatment strategies and making appropriate clinical decisions about individuals with a first episode of psychosis (FEP) is a complex and crucial task, with relevant impact in illness outcome. Treatment approaches in the early stages should go beyond choosing the right antipsychotic drug and should also address tractable factors influencing the risk of relapse. Effectiveness and likely metabolic and endocrine disturbances differ among second-generation antipsychotics (SGAs) and should guide the choice of the first-line treatment...
December 2016: Neurology and Therapy
Enrico Paolini, Patrizia Moretti, Michael T Compton
Although delusions represent one of the core symptoms of psychotic disorders, it is remarkable that few studies have investigated distinct delusional themes. We analyzed data from a large sample of first-episode psychosis patients (n=245) to understand relations between delusion types and demographic and clinical correlates. First, we conducted a principal component analysis (PCA) of the 12 delusion items within the Scale for the Assessment of Positive Symptoms (SAPS). Then, using the domains derived via PCA, we tested a priori hypotheses and answered exploratory research questions related to delusional content...
September 30, 2016: Psychiatry Research
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