#1
RANDOMIZED CONTROLLED TRIAL
David G Armstrong, Lawrence A Lavery
BACKGROUND: Diabetic foot wounds, particularly those secondary to amputation, are very complex and difficult to treat. We investigated whether negative pressure wound therapy (NPWT) improves the proportion and rate of wound healing after partial foot amputation in patients with diabetes. METHODS: We enrolled 162 patients into a 16-week, 18-centre, randomised clinical trial in the USA. Inclusion criteria consisted of partial foot amputation wounds up to the transmetatarsal level and evidence of adequate perfusion...
November 12, 2005: Lancet
#2
REVIEW
Joan Webster, Paul Scuffham, Monica Stankiewicz, Wendy P Chaboyer
BACKGROUND: Indications for the use of negative pressure wound therapy (NPWT) are broadening with a range of systems now available on the market, including those designed for use on clean, closed incisions and skin grafts. Reviews have concluded that the evidence for the effectiveness of NPWT remains uncertain, however, it is a rapidly evolving therapy. Consequently, an updated systematic review of the evidence for the effects of NPWT on postoperative wounds expected to heal by primary intention is required...
October 7, 2014: Cochrane Database of Systematic Reviews
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