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https://www.readbyqxmd.com/read/26483395/association-of-sex-hormone-binding-globulin-and-free-testosterone-with-mortality-in-men-with-type-2-diabetes-mellitus
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Aye N Tint, Rudolf Hoermann, Henry Wong, Elif I Ekinci, Richard J MacIsaac, George Jerums, Jeffrey D Zajac, Mathis Grossmann
OBJECTIVE: Low circulating testosterone levels have been associated with increased mortality in men. We hypothesized that the prognostic role of testosterone in men with type 2 diabetes mellitus (T2DM) is influenced by its carrier protein sex hormone-binding globulin (SHBG). DESIGN: We conducted a prospective cohort study at a tertiary referral centre. METHODS: In total, 531 men with T2DM presenting to a diabetes clinic in 2004-2005 were followed prospectively until death, or July 31, 2014, and a survival analysis was performed...
January 2016: European Journal of Endocrinology
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